To the Editor: We read with great interest the article by Chong and Jalihal [1] regarding endoscopic management of biliary disorders during pregnancy which reaffirms that endoscopic retrograde cholangiopancreatography...To the Editor: We read with great interest the article by Chong and Jalihal [1] regarding endoscopic management of biliary disorders during pregnancy which reaffirms that endoscopic retrograde cholangiopancreatography(ERCP)is safe and effective in managing choledocholithiasis during pregnancy. The authors use ERCP under fluoroscopic guidance with lead apron shielding as well as non-fluoroscopic cannulation using bile flow and bile aspiration as indicators of successful展开更多
Microbes are commonly sensitive to shifts in the physiological and pathological state of their hosts,including mothers and babies.From this perspective,the microbiome may be a good indicator for diseases during pregna...Microbes are commonly sensitive to shifts in the physiological and pathological state of their hosts,including mothers and babies.From this perspective,the microbiome may be a good indicator for diseases during pregnancy and has the potential to be used for perinatal health monitoring.This is embodied in the application of microbiome from multi body sites for auxiliary diagnosis,early prediction,prolonged monitoring,and retrospective diagnosis of pregnancy and infant complications,as well as nutrition management and health products developments of mothers and babies.Here we summarized the progress in these areas and explained that the microbiome of different body sites is sensitive to different diseases and their microbial biomarkers may overlap between each other,thus we need to make a diagnosis prudently for those diseases.Based on the microbiome variances and additional anthropometric and physical data,individualized responses of mothers and neonates to meals and probiotics/prebiotics were predictable,which is of importance for precise nutrition and probiotics/prebiotics managements and developments.Although a great deal of encouraging performance was manifested in previous studies,the efficacy could be further improved by combining multi-aspect data such as multi-omics and time series analysis in the future.This review reconceptualizes maternal and infant health from a microbiome perspective,and the knowledge in it may inspire the development of new options for the prevention and treatment of adverse pregnancy outcomes and bring a leap forward in perinatal health care.展开更多
文摘To the Editor: We read with great interest the article by Chong and Jalihal [1] regarding endoscopic management of biliary disorders during pregnancy which reaffirms that endoscopic retrograde cholangiopancreatography(ERCP)is safe and effective in managing choledocholithiasis during pregnancy. The authors use ERCP under fluoroscopic guidance with lead apron shielding as well as non-fluoroscopic cannulation using bile flow and bile aspiration as indicators of successful
基金This work was supported by the National Key R&D Program of China(2022YFA1304102)the National Natural Science Foundation of China(32070122),the Chinese Universities Scientific Fund(2022RC027)the 2115 Talent Development Program of China Agricultural University.The authors thank Liwen Xiao,Bing Zhang,Jinyang Zhang,Liuling Ma,Xiaoai Zhang,Xiaoqing Li,and Fangqing Zhao for their contributions in our previously published research paper related to this review.
文摘Microbes are commonly sensitive to shifts in the physiological and pathological state of their hosts,including mothers and babies.From this perspective,the microbiome may be a good indicator for diseases during pregnancy and has the potential to be used for perinatal health monitoring.This is embodied in the application of microbiome from multi body sites for auxiliary diagnosis,early prediction,prolonged monitoring,and retrospective diagnosis of pregnancy and infant complications,as well as nutrition management and health products developments of mothers and babies.Here we summarized the progress in these areas and explained that the microbiome of different body sites is sensitive to different diseases and their microbial biomarkers may overlap between each other,thus we need to make a diagnosis prudently for those diseases.Based on the microbiome variances and additional anthropometric and physical data,individualized responses of mothers and neonates to meals and probiotics/prebiotics were predictable,which is of importance for precise nutrition and probiotics/prebiotics managements and developments.Although a great deal of encouraging performance was manifested in previous studies,the efficacy could be further improved by combining multi-aspect data such as multi-omics and time series analysis in the future.This review reconceptualizes maternal and infant health from a microbiome perspective,and the knowledge in it may inspire the development of new options for the prevention and treatment of adverse pregnancy outcomes and bring a leap forward in perinatal health care.
