“主题陈述+应用实践”模式在“社会学概论”课程教学中的运用——以H高校社会工作专业为例

文章通过对H高校“社会学概论”课程传统教学模式进行诊析,发现存在教学内容上重知识传授、轻立德树人;教学设计上重理论灌输、轻实践教学;教学方法上重教师主导、轻学生参与等问题。因此,课程教学团队以建构主义学习理论为指导,秉持“为学习者设计教学”的理念,创新性地提出以“主题陈述+应用实践”(Presentation+Practice)为核心的教学模式。该模式在理论教学部分增设“悦读经典”新环节,与学生共同选择高质量文献进行研讨,培养学生的研究能力与表达能力;在实践教学部分,创造性地移植并导入工科专业的“课程设计”环节,要求学生选择研究主题进行社会实践、撰写研究报告,帮助学生初步形成了运用专业理论知识和技术解决相关工作中实际问题的本领,提升了学生的能力。这一教学模式的创新契合“00后”大学生的学情特点,取得了显著的教学成效。

深度学习对截断类密钥扩展算法的强度测试

密钥扩展算法的强度是影响分组密码算法安全性的重要因素之一。在实际应用中,通过子密钥还原主密钥,对算法可靠性也构成了一定威胁,但是却没有足够的研究专门对其进行安全强度分析。关注轻量级分组密码一类带有截断运算的密钥扩展算法,并根据算法将初始密钥比特分为截断位和非截断位。使用深度学习技术,通过根据最后一轮子密钥还原初始密钥的方式探索这类密钥扩展算法的强度。训练全连接网络对非截断位恢复准确率均高于截断位;训练卷积网络还原初始密钥绝大部分比特的准确率大于0.7,根据训练效果进一步辅助分析轻量级分组密码PRESENT、GIFT和MIBS的截断类密钥扩展算法的安全性强度。

基于Present算法的无线网络通信数据安全加密方法

为降低无线网络通信中数据传输节点的损失系数,引进Present算法,设计一种针对无线网络通信数据的安全加密方法。将贝叶斯定理作为参照,计算得到无线网络通信中数据处于安全状态的概率,推断得到数据通信的安全等级,实现对无线网络通信数据类别的划分;引进Present算法,生成无线网络通信数据轮密钥;根据窗口分割的结果,提取通信网络敏感数据,设定无线网络通信数据的时间序列,实现对无线网络通信数据中敏感数据的主动安全加密。实验结果表明:所提方法应用效果较好,可以将加密后节点损失系数控制在一个相对较低的水平,通过此种方式,降低节点在通信与传输信息时的损失。

Chlorfenapyr poisoning:mechanisms,clinical presentations,and treatment strategies

BACKGROUND:Chlorfenapyr is used to kill insects that are resistant to organophosphorus insecticides.Chlorfenapyr poisoning has a high mortality rate and is difficult to treat.This article aims to review the mechanisms,clinical presentations,and treatment strategies for chlorfenapyr poisoning.DATA RESOURCES:We conducted a review of the literature using PubMed,Web of Science,and SpringerLink from their beginnings to the end of October 2023.The inclusion criteria were systematic reviews,clinical guidelines,retrospective studies,and case reports on chlorfenapyr poisoning that focused on its mechanisms,clinical presentations,and treatment strategies.The references in the included studies were also examined to identify additional sources.RESULTS:We included 57 studies in this review.Chlorfenapyr can be degraded into tralopyril,which is more toxic and reduces energy production by inhibiting the conversion of adenosine diphosphate to adenosine triphosphate.High fever and altered mental status are characteristic clinical presentations of chlorfenapyr poisoning.Once it occurs,respiratory failure occurs immediately,ultimately leading to cardiac arrest and death.Chlorfenapyr poisoning is diflcult to treat,and there is no specific antidote.CONCLUSION:Chlorfenapyr is a new pyrrole pesticide.Although it has been identified as a moderately toxic pesticide by the World Health Organization(WHO),the mortality rate of poisoned patients is extremely high.There is no specific antidote for chlorfenapyr poisoning.Therefore,based on the literature review,future efforts to explore rapid and effective detoxification methods,reconstitute intracellular oxidative phosphorylation couplings,identify early biomarkers of chlorfenapyr poisoning,and block the conversion of chlorfenapyr to tralopyril may be helpful for emergency physicians in the diagnosis and treatment of this disease.

Clustering in nuclei:progress and perspectives

Nucleus is essentially composed of protons and neutrons,which are commonly known as nucleons.Interestingly,some of nucleons may group together and exhibit collective behavior inside a nucleus.Such clustering efects have been known since the early stages of nuclear physics because of the observation and description ofα-cluster decay from many heavy nuclei.Subsequent studies demonstrated that cluster structures exist in many nuclear systems,especially in weakly bound or excited states,and are complementary to the shell-like structures.In this review article,we provide a brief historical recall of the feld,and follow it with a conceptual and logical description of the major theoretical models that have been frequently applied in the literature to describe nuclear clustering.Experimental methods and progress are outlined,recent outcomes are emphasized,and perspectives relevant to future studies of heavy neutron-rich systems are discussed.

Impact of nanoparticles on immune cells and their potential applications in cancer immunotherapy

Nanoparticles represent a heterogeneous collection of materials,whether natural or synthetic,with dimensions aligning in the nanoscale.Because of their intense manifestation with the immune system,they can be harvested for numerous bio-medical and biotechnological advancements mainly in cancer treatment.This review article aims to scrutinize various types of nanoparticles that interact differently with immune cells like macrophages,dendritic cells,T lymphocytes,and natural killer(NK)cells.It also underscores the importance of knowing how nanoparticles influence immune cell functions,such as the production of cytokines and the presentation of antigens which are crucial for effective cancer immunotherapy.Hence overviews of bio-molecular mechanisms are provided.Nanoparticles can improve antigen presentation,boost T-cell responses,and overcome the immunosuppressive tumor environment.The regulatory mechanisms,signaling pathways,and nanoparticle characteristics are also presented for a comprehensive understanding.We review the nanotechnology platform options and challenges in nanoparticlesbased immunotherapy,from an immunotherapy perspective including precise targeting,immune modulation,and potential toxicity,as well as personalized approaches based on individual patient and tumor characteristics.The development of emerging multifunctional nanoparticles and theranostic nanoparticles will provide new solutions for the precision and efficiency of cancer therapies in next-generation practice.

Signet-ring cell carcinoma of the transverse colon in a 10-year-old girl:A case report

BACKGROUND Signet-ring cell carcinoma(SRCC)is a rare subtype of colorectal cancer.The incidence of primary colonic SRCC is relatively rare in pediatric patients,with a limited number of reported cases currently available.The prognosis for this specific tumor type is unfavorable,and the preoperative diagnosis presents challenges,potentially leading to misdiagnosis.This case report describes the diagnosis of primary SRCC in the colon of a 10-year-old girl.CASE SUMMARY The patient was admitted to the hospital due to abdominal pain and vomiting.A computed tomography scan revealed an irregular mass with soft tissue density in her transverse colon,showing uneven density and multiple calcifications.The patient underwent surgical resection of the affected bowel and lymph node dissection,which was confirmed by pathological examination to be SRCC infiltrating both nerves and the entire intestinal wall.Additionally,tumor thrombus formation was observed in blood vessels and lymphatic vessels,multiple cancerous nodules were found in the omentum,and metastasis to 18 of 26 mesenteric lymph nodes examined.Immunohistochemistry for mismatch repair gene protein demonstrated microsatellite stability.No mutations in KRAS,NRAS,BRAF,or PIK3CA genes were detected through molecular pathology analysis.After surgery,she received standard chemotherapy for 8 cycles without tumor progression or other abnormalities during a 12-month follow-up period CONCLUSION Primary colonic SRCC is a rare malignant tumor with atypical clinical symptoms,and timely identification and intervention are crucial for improving the prognosis.

Recent Advances for Global Perspectives on Etiology, Pathophysiology, Clinical Presentations, and Management of Moyamoya Disease

Moyamoya disease (MMD) is a condition characterized by the gradual narrowing and blockage of blood vessels in the brain, specifically those in the circle of Willis and the arteries that supply it. This results in reduced blood flow and oxygen to the brain, leading to progressive symptoms and potential complications. The underlying pathophysiological mechanism remains elucidated. However, recent studies have highlighted numerous etiologic factors: abnormal immune complex responses, susceptibility genes, branched-chain amino acids, antibodies, heritable diseases, and acquired diseases, which may be the great potential triggers for the development of moyamoya disease. Its clinical presentation has varying degrees from transient asymptomatic events to significant neurological deficits. Moyamoya disease (MMD) shows different patterns in children and adults. Children with MMD are more susceptible to ischemic events due to decreased blood flow to the brain. Conversely, adults with MMD are more prone to hemorrhagic events involving brain bleeding. Children with MMD may experience a range of symptoms including motor impairments, sensory issues, seizures, headaches, dizziness, cognitive delays, or ongoing neurological problems. Although adults may present with similar clinical symptoms as children, they are more prone to experiencing sudden onset intraventricular, subarachnoid, or intracerebral hemorrhages. One of the challenges in moyamoya disease is the potential for misdiagnosis or delayed diagnosis, particularly when physicians fail to consider MMD as a possible cause in stroke patients. This review aims to provide a comprehensive overview of recent global studies on the pathophysiology of MMD, along with advancements in its management. Additionally, the review will delve into various surgical treatment options for MMD, as well as its rare occurrence alongside atrioventricular malformations. Exciting prospects include the use of autologous bone marrow transplant and the potential role of Connexin 43 protein treatment in the development of moyamoya disease.

Beyond the Usual Suspects (Aortic Dissection in Patients with Chronic Kidney Disease)

A comprehensive differential diagnosis is essential in the emergency department, even when patient presentations are atypical. Timely recognition of life-threatening conditions, such as aortic dissection, hinges on this critical diagnostic approach.

Thinking on Improving Presentation Teaching-Based on the Empirical Analysis of Presentation in College English Classes of Junior Non-English Majors in Universities of Science and Engineering

Based on the empirical investigation of presentation in college English classes for junior non-English majors in science and engineering universities,the author explains her own thinking on how to improve presentation teaching from four aspects:setting teaching objectives,selecting teaching contents,using teaching methods,and evaluating and implementing methods.

Cultivate Critical Thinking Ability via Students’ Presentations in College English Classes

In the new era when demands for flexible intellectual skills are increasing,strengthening the cultivation of critical thinking ability of students has become one of the key purposes of higher education.This paper intends to discuss how to cultivate students’critical thinking ability through English classroom presentations.It points out that during the whole process,teachers’guidance plays an indispensable role.Only when both teachers and students are aware that classroom presentations are a golden opportunity for the cultivation of students’critical thinking ability and carry this awareness into their English classes,can English presentations be brought into full play.

Clinical Presentation and Treatment Outcomes of Pregnancy-Related Acute Kidney Injury among Pregnant Women Admitted at the Benjamin Mkapa Hospital in Tanzania

Background: Globally, PRAKI is among the leading causes of death in pregnant women. The prevalence, causes and outcome of this condition vary among countries due to differences in environmental, socioeconomic, and health delivery systems. The common causes that have been reported in several studies are PIH, Haemorrhages and Sepsis while the outcomes may be either complete renal recovery, progression to CKD and hence dialysis dependency or death. This study aimed at determining clinical presentation and treatment outcomes of Pregnancy-Related Acute Kidney Injury in Pregnant women admitted at the Benjamin Mkapa Hospital, Dodoma, Tanzania. Results: Out of 4007 pregnant women who were admitted to the maternity ward 51 pregnant women were found to have PRAKI. Of those with PRAKI, 74.5% were between 21 to 25 years. The leading causes of PRAKI were PPH 12 (23.53%), Eclampsia 12 (23.53%), and pre-eclampsia 12 (23.5%). Hemodialysis therapy was provided to 22 (43.1%) patients, 15 (29.4%) individuals recovered spontaneously with medical management and 14 (27.5%) missed haemodialysis therapy due to various reasons. The mortality due to PRAKI was 17 (33.3%). Conclusion and Recommendation: Pre-eclampsia/eclampsia and post-partum haemorrhage were found to be the main causes of PRAKI. The mortality related to PRAKI is high and Hemodialysis therapy is vital help to prevent deaths for pregnant women with PRAKI. Pregnant women who develop acute kidney injury should be followed closely and a nephrologist should be consulted early. Early referral should be done by the lower level facilities for all at-risk pregnant women to a specialized multidisciplinary health facility.

Research on Strategies for Enhancing the Ability of Chinese German Learners to Tell Chinese Stories Through Short Videos

In the age of new media,short videos play an increasingly important role in international cultural exchange.However,German learners often encounter challenges when producing and sharing short videos due to factors such as technology and language proficiency.Such challenges can affect the professionalism and attractiveness of the videos.This study focuses on German learners at the University of Shanghai for Science and Technology.The aim of this study is to investigate students’experiences in producing short videos,identify issues through surveys and interviews,and concentrate on editing skills,language proficiency,and intercultural communication abilities.It proposes strategies for developing these skills and aims to provide insights for German and other foreign language learners in telling Chinese stories using short videos.

Fournier’s Gangrene: 13-Year Experience in a Tertiary Center, North Eastern Nigeria

Background: Fournier’s gangrene is a fulminant infection of the genitourinary tract characterized by progressive necrosis of the skin and subcutaneous tissue of the external genitalia. Initially mainly seen involving the scrotum of elderly men with different moods of occurrence each unpleasantly lethal. With varying types of presentation only one thing has remained constant;the poor prognosis of this condition. Purpose/Aim: Thus, it’s important to study the trends of the presentation of this condition laying emphasis on the challenges in the management of these patients;both the negative and positive prognostic factors. Materials and Methods: Urology ward record books, clinic record books and operating theater records were used to identify patients managed for Fournier gangrene in ATBUTH Bauchi. A retrospective study of the medical files of all the patients managed from January 2011 to January 2024 was done. Data was analyzed using SPSS version 29. Results: Data from 47 patients seen during the period of study were carefully collected and analyzed. The age range is 2 weeks to 97 years. There were two neonates, one at 2nd week of life and the other at 3rd week. Mortality rate is 36%. The average time duration before presentation for patients that died was two weeks, a minimum of 9 days prior to presentation and a maximum of 21 days, about 10 of which came in septic shock and the remaining presented with fever and very extensive necrotizing fasciitis of the perineum. All the patients that died had diabetes mellitus as a comorbidity except the neonate. All the patients that survived were much younger, all were below 60 years of age (2 weeks - 53 years). Conclusion: Here, we share our experience managing patients with Fournier’s gangrene in our facility in the past 13-year period from January 2011 to January 2024. .

Mathematical Modeling of Multiple Capacitor Coupled Substations (CCS) Impact on Transmission Lines and Approaches for Ferroresonance Suppression

Rural electrification remains a critical challenge in achieving equitable access to electricity, a cornerstone for poverty alleviation, economic growth, and improved living standards. Capacitor Coupled Substations (CCS) offer a promising solution for delivering cost-effective electricity to these underserved areas. However, the integration of multiple CCS units along a transmission network introduces complex interactions that can significantly impact voltage, current, and power flow. This study presents a detailed mathematical model to analyze the effects of varying distances and configurations of multiple CCS units on a transmission network, with a focus on voltage stability, power quality, and reactive power fluctuations. Furthermore, the research addresses the phenomenon of ferroresonance, a critical issue in networks with multiple CCS units, by developing and validating suppression strategies to ensure stable operation. Through simulation and practical testing, the study provides insights into optimizing CCS deployment, ultimately contributing to more reliable and efficient rural electrification solutions.

Research on Heterogeneous Information Network Link Prediction Based on Representation Learning

A heterogeneous information network,which is composed of various types of nodes and edges,has a complex structure and rich information content,and is widely used in social networks,academic networks,e-commerce,and other fields.Link prediction,as a key task to reveal the unobserved relationships in the network,is of great significance in heterogeneous information networks.This paper reviews the application of presentation-based learning methods in link prediction of heterogeneous information networks.This paper introduces the basic concepts of heterogeneous information networks,and the theoretical basis of representation learning,and discusses the specific application of the deep learning model in node embedding learning and link prediction in detail.The effectiveness and superiority of these methods on multiple real data sets are demonstrated by experimental verification.

Losartan Induced Angioedema, a Rare Case Report and the Dilemma of Using Angiotensin II Receptor Blockers in Patients with Previous Angioedema with Angiotensin Converting Enzyme Inhibitors

Angiotensin Receptor Blockers (ARB) are used as an alternative of Angiotensin Converting Enzyme Inhibitors (ACEI) in patients where ACEIs cannot be used because of their known adverse effects, cough and angioedema. Thus ARB induced angioedema is considered to be a rare phenomenon and it is continued to be used as an alternatives of ACEIs. In this case report, we reported a case of 78-year-old gentleman who presented to emergency department with losartan, an ARB induced angioedema, who did not have history of any previous use of ACEIs. He was given steroids and antihistamine as a treatment. His angioedema resolved rapidly and he was discharged after six hours of emergency department (ED) observation with stable hemodynamically. We, the authors by reporting this case, wants to make clinicians aware ARB, however rarely, can cause angioedema, which can be life threatening if clinicians are not aware of it and diagnose and stop the offending drug promptly and treat it early.

PRESENT密码代数故障攻击

提出了一种新的PRESENT密码故障分析方法——代数故障攻击。将代数攻击和故障攻击相结合,首先利用代数攻击方法建立密码算法等效布尔代数方程组;然后通过故障攻击手段获取错误密文信息,并将故障差分和密文差分转化为额外的布尔代数方程组;最后使用CryptoMiniSAT解析器求解方程组恢复密钥。结果表明:在PRESENT-80的第29轮注入宽度为4的故障,故障位置和值未知时,2次故障注入可在50s内恢复64bit后期白化密钥,将PRESENT-80密钥搜索空间降低为216,经1min暴力破解恢复完整主密钥;和现有PRESENT故障攻击相比,该攻击所需样本量是最小的;此外该代数故障分析方法也可为其他分组密码故障分析提供一定思路。

基于Feistel结构的超轻量级分组密码算法(PFP)

面向无线终端资源受限环境对加密算法的应用需求,借鉴PRESENT算法的设计思想,采用Feistel结构,并修改扩散层的P置换,设计了一种超轻量级分组密码算法PFP。其硬件实现需要1355GE,优于PRESENT算法,满足资源极端受限环境的需求(2000GE以下)。速度测试结果表明,PFP算法的软件实现效率约为PRESENT算法的1.5倍。依赖性测试、线性分析、差分分析、不可能差分分析和密钥编排攻击表明,PFP算法满足轻量级分组密码的安全需求。

PRESENT密码硬件语言实现及其优化研究

PRESENT密码算法是2007年提出来的一种轻量级分组密码算法,适合于物联网环境下的安全加密.研究了PRESENT密码算法结构,在原算法结构基础上优化了密钥扩展的实现方法,把密钥扩展不在原算法图的右边实现,而是放入轮运算中.在硬件实现上,31轮重复运算只实现一次,采用31次调用完成,从而可以大幅节约PRESENT密码实现面积.最后,对PRESENT密码的各核心模块进行了Verilog HDL实现,并分模块进行了测试数据验证.经FPGA综合下载后,实验结果表明优化的PRESENT密码硬件语言实现正确,面积相对原始算法更少.