Acupuncture as a vital component of traditional medical systems of the Far East has been used to restore and maintain health for over three millennia. However, the neurobiological correlates of this therapy remain lar...Acupuncture as a vital component of traditional medical systems of the Far East has been used to restore and maintain health for over three millennia. However, the neurobiological correlates of this therapy remain largely unknown. The purpose of this study was therefore to determine the effect of enpishin acupuncture (press tack needles (PTN)) on autonomic function, WBC count, and oxidative stress between subjects that received either verum or placebo PTN treatment. Twenty men (mean(SD) age: 36.7(5.1) years) who provided oral consent were randomized to receive either verum PTN (n = 9) or placebo PTN (n = 11). Bi-Digital O-Ring Test (BDORT) was used to select the acupoints for each participant. Autonomic function and oxidative stress level were analyzed before and after the treatment via heart rate variability (HRV) and free radical analysis system (FRAS4), respectively. Pre- and post-treatment WBC count was also evaluated. Verum PTN group had a statistically significant increase (p = 0.008) in Ln TP, an index of overall autonomic activity. Subjects in this group also had a significantly greater (p = 0.006) variation in Ln TP than the placebo PTN group in response to the treatment. Similarly, Ln HF of subjects receiving verum PTN showed a marked increase (p = 0.0026) after the treatment. Moreover, a significantly greater (p < 0.001) variation in mean Ln HF before and after the treatment was noted in the verum group than the placebo group, reflecting a greater parasympathetic activation in the former. In contrast, sympathetic activity was not significantly influenced by verum PTN based on the lack of observed changes in LF/HF ratio. In addition, both groups failed to demonstrate significant variations in pre- and post-treatment mean Ln LF/HF ratio. Further, no significant intergroup difference was found with regard to mean variation in Ln LF/HF ratio. Verum PTN did not induce significant changes in WBC count and markers of oxidative stress, namely reactive oxygen species (ROM) and biological antioxidant potential (BAP). However, a comparison of variations in pre- and post-treatment mean WBC count showed a significant difference (p = 0.020) between the two treatment modes: verum group showed a slight increase (225 ± 384.5), while placebo group showed a minimal decrease (–190 ± 272.6). Our findings suggest that PTN increases overall autonomic activity, particularly the parasympathetic function.展开更多
This article introduces 186 cases of sciatica treated by acupuncture with thebalance of the human body as a whole.Jianzhen(SI 9)was selected as the main acupoint.Atthe same time,Fengchi(GB 20)or Dazhui(GV14)was select...This article introduces 186 cases of sciatica treated by acupuncture with thebalance of the human body as a whole.Jianzhen(SI 9)was selected as the main acupoint.Atthe same time,Fengchi(GB 20)or Dazhui(GV14)was selected as the pressing point.Therewas statistically significant difference(p【0.001)between the treatment group and the othertwo control groups.In the result,147 cases were basically cured.28 markedly improved,5improved and the total effective rate was 97.31%.展开更多
Radical mastectomy may lead to suppression of cellular immune function in patients with malignant tumors,and affect the quality of life(QOL)of patients.Immune suppression is a common cause of complications and adverse...Radical mastectomy may lead to suppression of cellular immune function in patients with malignant tumors,and affect the quality of life(QOL)of patients.Immune suppression is a common cause of complications and adverse reactions in adjuvant therapy after radical mastectomy of breast cancer.Currently,there are few proven effective treatments for immune suppression.Therefore,it’s necessary to develop a new treatment method.Press needle is widely used in clinical practice.However,there have been relatively few studies that evaluate the effects of press needle on postoperative immune function.The aim of the present study is to assess the effects of press needle on immune function and QOL in female breast cancer patients undergoing radical mastectomy.This study will be a single-center,randomized and single-blinded trial.Totally 78 eligible patients will be randomized in a ratio of 1:1 to the press needle group or the sham press needle group.During the treatment phase,patients will undergo five times weekly of verum press needle or sham press needle for 2 weeks.The primary outcome measures will be the peripheral blood levels of CD8^(+),CD4^(+),CD3^(+),and CD4^(+)/CD8^(+)T cells.The secondary outcome measures will be the changes of patients’QOL,evaluated by the Karnofsky Performance Scale score and the EORTC core quality of life questionnaire(EORTC QLQ-C30).Furthermore,5-year survival rate and recurrence rate will be evaluated.Safety and adverse events will be assessed at each visit.The results of this on-going study will provide clinical evidence for the effects and safety of press needle on immune function and QOL in patients after breast cancer resection compared with sham press needle.展开更多
目的:观察揿针结合重复经颅磁刺激(repeated transcranial magnetic stimulation,rTMS)治疗急性颅脑损伤的效果。方法:选取2020年1月—2023年12月江西省儿童医院收治的60例急性颅脑损伤患儿作为研究对象,采用随机数字表法分为对照组和...目的:观察揿针结合重复经颅磁刺激(repeated transcranial magnetic stimulation,rTMS)治疗急性颅脑损伤的效果。方法:选取2020年1月—2023年12月江西省儿童医院收治的60例急性颅脑损伤患儿作为研究对象,采用随机数字表法分为对照组和观察组,各30例。对照组患儿采用常规针刺结合rTMS治疗,观察组患儿采用揿针结合rTMS治疗。两组均连续干预4周。对比两组临床疗效、肌力、粗大运动功能、肌张力。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗前,两组肌力及粗大运动功能评估量表-88(gross motor function measure,GMFM-88)、改良Ashworth量表(modified Ashworth scale,MAS)评分比较,差异均无统计学意义(P>0.05);治疗1周后及治疗结束后,观察组GMFM-88评分均高于对照组,治疗结束后,观察组MAS评分低于对照组,差异均有统计学意义(P<0.05);治疗结束后,两组肌力均优于治疗前,差异均有统计学意义(P<0.05)。结论:对急性颅脑损伤患儿实施揿针结合rTMS治疗可促进肌力与粗大运动功能恢复,整体疗效突出。展开更多
目的:分析基于子午流注理论运用揿针联合脐疗治疗糖尿病便秘的效果。方法:选择无锡市中医医院2022年2月—2024年1月诊治的106例糖尿病便秘患者,将其随机分为两组,各53例。对比组给予大黄、肉苁蓉脐疗贴治疗,观察组在对比组基础上给予基...目的:分析基于子午流注理论运用揿针联合脐疗治疗糖尿病便秘的效果。方法:选择无锡市中医医院2022年2月—2024年1月诊治的106例糖尿病便秘患者,将其随机分为两组,各53例。对比组给予大黄、肉苁蓉脐疗贴治疗,观察组在对比组基础上给予基于子午流注理论的揿针治疗。比较两组临床疗效、血糖指标、便秘症状积分。结果:观察组临床总有效率(96.23%)高于对比组(75.47%),差异有统计学意义(P<0.05)。观察组治疗后空腹血糖(FPG)、餐后2 h血糖(2 h PG)均低于对比组,差异均有统计学意义(P<0.05)。观察组治疗后排便频率、腹胀、排便不尽、排便时间、粪便性状、排便困难积分均低于对比组,差异均有统计学意义(P<0.05)。结论:基于子午流注理论运用揿针联合脐疗可有效缓解糖尿病便秘患者便秘症状,调控血糖,临床疗效显著。展开更多
文摘Acupuncture as a vital component of traditional medical systems of the Far East has been used to restore and maintain health for over three millennia. However, the neurobiological correlates of this therapy remain largely unknown. The purpose of this study was therefore to determine the effect of enpishin acupuncture (press tack needles (PTN)) on autonomic function, WBC count, and oxidative stress between subjects that received either verum or placebo PTN treatment. Twenty men (mean(SD) age: 36.7(5.1) years) who provided oral consent were randomized to receive either verum PTN (n = 9) or placebo PTN (n = 11). Bi-Digital O-Ring Test (BDORT) was used to select the acupoints for each participant. Autonomic function and oxidative stress level were analyzed before and after the treatment via heart rate variability (HRV) and free radical analysis system (FRAS4), respectively. Pre- and post-treatment WBC count was also evaluated. Verum PTN group had a statistically significant increase (p = 0.008) in Ln TP, an index of overall autonomic activity. Subjects in this group also had a significantly greater (p = 0.006) variation in Ln TP than the placebo PTN group in response to the treatment. Similarly, Ln HF of subjects receiving verum PTN showed a marked increase (p = 0.0026) after the treatment. Moreover, a significantly greater (p < 0.001) variation in mean Ln HF before and after the treatment was noted in the verum group than the placebo group, reflecting a greater parasympathetic activation in the former. In contrast, sympathetic activity was not significantly influenced by verum PTN based on the lack of observed changes in LF/HF ratio. In addition, both groups failed to demonstrate significant variations in pre- and post-treatment mean Ln LF/HF ratio. Further, no significant intergroup difference was found with regard to mean variation in Ln LF/HF ratio. Verum PTN did not induce significant changes in WBC count and markers of oxidative stress, namely reactive oxygen species (ROM) and biological antioxidant potential (BAP). However, a comparison of variations in pre- and post-treatment mean WBC count showed a significant difference (p = 0.020) between the two treatment modes: verum group showed a slight increase (225 ± 384.5), while placebo group showed a minimal decrease (–190 ± 272.6). Our findings suggest that PTN increases overall autonomic activity, particularly the parasympathetic function.
文摘This article introduces 186 cases of sciatica treated by acupuncture with thebalance of the human body as a whole.Jianzhen(SI 9)was selected as the main acupoint.Atthe same time,Fengchi(GB 20)or Dazhui(GV14)was selected as the pressing point.Therewas statistically significant difference(p【0.001)between the treatment group and the othertwo control groups.In the result,147 cases were basically cured.28 markedly improved,5improved and the total effective rate was 97.31%.
基金Supported by Study of Press Needle on Immune Function in Breast Cancer Patients after Radical Mastectomy(No.20ZL15)Enhancement of Scientific Research Capacity of“Hundred Talents Program”(No.20-Q17)。
文摘Radical mastectomy may lead to suppression of cellular immune function in patients with malignant tumors,and affect the quality of life(QOL)of patients.Immune suppression is a common cause of complications and adverse reactions in adjuvant therapy after radical mastectomy of breast cancer.Currently,there are few proven effective treatments for immune suppression.Therefore,it’s necessary to develop a new treatment method.Press needle is widely used in clinical practice.However,there have been relatively few studies that evaluate the effects of press needle on postoperative immune function.The aim of the present study is to assess the effects of press needle on immune function and QOL in female breast cancer patients undergoing radical mastectomy.This study will be a single-center,randomized and single-blinded trial.Totally 78 eligible patients will be randomized in a ratio of 1:1 to the press needle group or the sham press needle group.During the treatment phase,patients will undergo five times weekly of verum press needle or sham press needle for 2 weeks.The primary outcome measures will be the peripheral blood levels of CD8^(+),CD4^(+),CD3^(+),and CD4^(+)/CD8^(+)T cells.The secondary outcome measures will be the changes of patients’QOL,evaluated by the Karnofsky Performance Scale score and the EORTC core quality of life questionnaire(EORTC QLQ-C30).Furthermore,5-year survival rate and recurrence rate will be evaluated.Safety and adverse events will be assessed at each visit.The results of this on-going study will provide clinical evidence for the effects and safety of press needle on immune function and QOL in patients after breast cancer resection compared with sham press needle.
文摘目的观察耳穴揿针联合栀黄散穴位贴敷对胆石症患者的应用效果。方法将120例患者随机分为A组:耳穴揿针组(40例),B组:穴位贴敷组(40例),C组:联合治疗组(40例)。A组患者在常规西医治疗的基础上加用耳穴揿针治疗,按压4~6次/d,1~3 min/次,5 d 1个疗程,双耳交替操作。B组患者在常规西医治疗的基础上加用栀黄散穴位贴敷,贴敷于双侧胆俞穴、双侧肝俞穴、右侧期门穴、双侧阳陵泉穴,贴敷时间为4~6 h,2次/d,5 d 1个疗程。C组患者在常规西医治疗的基础上联合使用耳穴揿针和栀黄散穴位贴敷治疗。通过疼痛数值评分量表(NRS)比较3组患者治疗后0.5、1、2、24、48 h疼痛评分;治疗前后3组患者C反应蛋白(C-reactive protein,CRP)、胆红素、肝功能(ALT)变化情况;通过B超检查治疗前后胆囊收缩功能、胆囊壁厚度。结果干预后3组患者疼痛评分时间效应值、CRP、胆红素、ALT数值、胆囊壁厚度均低于干预前,胆囊收缩功能较干预前增加,差异具有统计学意义(P<0.05),A组、B组两组患者干预后疼痛评分时间效应值、CRP、胆红素、ALT数值、胆囊壁厚度、胆囊收缩功能比较,差异无统计学意义(P>0.05)。C组患者干预后疼痛评分时间效应值、CRP、胆红素、ALT数值、胆囊壁厚度均低于A、B两组,胆囊收缩功能高于A、B两组,差异具有统计学意义(P<0.05)。结论耳穴揿针和栀黄散穴位贴敷应用于胆石症患者,均可减轻患者的疼痛反应,降低炎症作用,促进肝功能恢复,增强胆囊收缩功能。将两者联合应用,临床疗效更加显著,能够加速患者康复,值得临床推广。
文摘目的:观察揿针结合重复经颅磁刺激(repeated transcranial magnetic stimulation,rTMS)治疗急性颅脑损伤的效果。方法:选取2020年1月—2023年12月江西省儿童医院收治的60例急性颅脑损伤患儿作为研究对象,采用随机数字表法分为对照组和观察组,各30例。对照组患儿采用常规针刺结合rTMS治疗,观察组患儿采用揿针结合rTMS治疗。两组均连续干预4周。对比两组临床疗效、肌力、粗大运动功能、肌张力。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗前,两组肌力及粗大运动功能评估量表-88(gross motor function measure,GMFM-88)、改良Ashworth量表(modified Ashworth scale,MAS)评分比较,差异均无统计学意义(P>0.05);治疗1周后及治疗结束后,观察组GMFM-88评分均高于对照组,治疗结束后,观察组MAS评分低于对照组,差异均有统计学意义(P<0.05);治疗结束后,两组肌力均优于治疗前,差异均有统计学意义(P<0.05)。结论:对急性颅脑损伤患儿实施揿针结合rTMS治疗可促进肌力与粗大运动功能恢复,整体疗效突出。
文摘目的:分析基于子午流注理论运用揿针联合脐疗治疗糖尿病便秘的效果。方法:选择无锡市中医医院2022年2月—2024年1月诊治的106例糖尿病便秘患者,将其随机分为两组,各53例。对比组给予大黄、肉苁蓉脐疗贴治疗,观察组在对比组基础上给予基于子午流注理论的揿针治疗。比较两组临床疗效、血糖指标、便秘症状积分。结果:观察组临床总有效率(96.23%)高于对比组(75.47%),差异有统计学意义(P<0.05)。观察组治疗后空腹血糖(FPG)、餐后2 h血糖(2 h PG)均低于对比组,差异均有统计学意义(P<0.05)。观察组治疗后排便频率、腹胀、排便不尽、排便时间、粪便性状、排便困难积分均低于对比组,差异均有统计学意义(P<0.05)。结论:基于子午流注理论运用揿针联合脐疗可有效缓解糖尿病便秘患者便秘症状,调控血糖,临床疗效显著。
