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Towards the performance limit of catenary meta-optics via field-driven optimization 被引量:1
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作者 Siran Chen Yingli Ha +8 位作者 Fei Zhang Mingbo Pu Hanlin Bao Mingfeng Xu Yinghui Guo Yue Shen Xiaoliang Ma Xiong Li Xiangang Luo 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2024年第5期33-42,共10页
Catenary optics enables metasurfaces with higher efficiency and wider bandwidth,and is highly anticipated in the imaging system,super-resolution lithography,and broadband absorbers.However,the periodic boundary approx... Catenary optics enables metasurfaces with higher efficiency and wider bandwidth,and is highly anticipated in the imaging system,super-resolution lithography,and broadband absorbers.However,the periodic boundary approximation without considering aperiodic electromagnetic crosstalk poses challenges for catenary optical devices to reach their performance limits.Here,perfect control of both local geometric and propagation phases is realized through field-driven optimization,in which the field distribution is calculated under real boundary conditions.Different from other optimization methods requiring a mass of iterations,the proposed design method requires less than ten iterations to get the efficiency close to the optimal value.Based on the library of shape-optimized catenary structures,centimeter-scale devices can be designed in ten seconds,with the performance improved by ~15%.Furthermore,this method has the ability to extend catenary-like continuous structures to arbitrary polarization,including both linear and elliptical polarizations,which is difficult to achieve with traditional design methods.It provides a way for the development of catenary optics and serves as a potent tool for constructing high-performance optical devices. 展开更多
关键词 catenary optics catenary structures field-driven optimization
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基于OPTICS聚类的电力通信网跨层保护系统设计
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作者 梁发亮 岳龙 李树勇 《电子设计工程》 2024年第18期163-167,共5页
电力通信网跨层传输数据时,受到噪声数据影响,导致跨层数据传输耗时长、电流畸变率高。为了保证跨层通信安全,设计基于密度的聚类算法(Ordering Points To Identify the Clustering Structure,OPTICS)的电力通信网跨层保护系统。构建并... 电力通信网跨层传输数据时,受到噪声数据影响,导致跨层数据传输耗时长、电流畸变率高。为了保证跨层通信安全,设计基于密度的聚类算法(Ordering Points To Identify the Clustering Structure,OPTICS)的电力通信网跨层保护系统。构建并联有源电力滤波器安全保护电路,保证三相四线制限幅后具有良好谐波补偿效果。通过跨层控制主动切换模块,实现目标通信链路下达指令的主动切换。对电力通信网跨层数据进行OPTICS聚类处理,结合Laplace机制添加对称指数分布噪声,将Laplace噪声添加到聚类簇中,输出添加噪声后结果存储在输出队列中,完成通信网跨层保护。由系统测试结果可知,该系统传输耗时少,且在10 s测试时间内跨层电流畸变率仅为21%,能够起到保护通信网跨层传输的作用。 展开更多
关键词 optics聚类 电力通信网 跨层保护 Laplace机制
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Special issue:Catenary optics and catenary electromagnetics
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作者 Qian Sun Minghui Hong 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2024年第5期1-4,共4页
As a natural mathematical form,a catenary is the curve that a hanging chain or cable adopts under its own weight when supported at its ends in a homogeneous gravitational field.This unique shape arises from the balanc... As a natural mathematical form,a catenary is the curve that a hanging chain or cable adopts under its own weight when supported at its ends in a homogeneous gravitational field.This unique shape arises from the balance of forces acting on each segment of the chain,resulting in a curve described by hyperbolic cosine functions.Catenary functions play pivotal roles in describing the electromagnetic field,intensity distribution,and dispersion of structured light on the sub-wavelength scale^(1). 展开更多
关键词 FUNCTIONS FIELD optics
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Solar adaptive optics systems for the New Vacuum Solar Telescope at the Fuxian Lake Solar Observatory
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作者 Lanqiang Zhang Xuejun Rao +8 位作者 Hua Bao Youming Guo Jinsheng Yang Nanfei Yan Xian Ran Dingkang Tong Xinlong Fan Zhongyi Feng Changhui Rao 《Astronomical Techniques and Instruments》 CSCD 2024年第2期95-104,共10页
Adaptive optics(AO)is essential for high-quality ground-based observations with large telescopes because it counters the impact of wavefront aberrations caused by atmospheric turbulence.The new vacuum solar telescope(... Adaptive optics(AO)is essential for high-quality ground-based observations with large telescopes because it counters the impact of wavefront aberrations caused by atmospheric turbulence.The new vacuum solar telescope(NVST)is one of the most important high-resolution solar observation instruments in the world.Three sets of solar adaptive optics systems have been developed and installed on this telescope:conventional adaptive optics,ground layer adaptive optics,and multi-conjugate adaptive optics.These have been in operation from 2018 to 2023.This paper details the development and application of solar adaptive optics on the NVST and discusses the newest instrumentation. 展开更多
关键词 Solar observation Adaptive optics Multi-conjugate adaptive optics
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A historical overview of nano-optics:From near-field optics to plasmonics
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作者 邓妙怡 朱星 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期134-145,共12页
Nano-optics is an emergent research field in physics that appeared in the 1980s,which deals with light–matter optical interactions at the nanometer scale.In early studies of nano-optics,the main concern focus is to o... Nano-optics is an emergent research field in physics that appeared in the 1980s,which deals with light–matter optical interactions at the nanometer scale.In early studies of nano-optics,the main concern focus is to obtain higher optical resolution over the diffraction limit.The researches of near-field imaging and spectroscopy based on scanning near-field optical microscopy(SNOM)are developed.The exploration of improving SNOM probe for near-field detection leads to the emergence of surface plasmons.In the sense of resolution and wider application,there has been a significant transition from seeking higher resolution microscopy to plasmonic near-field modulations in the nano-optics community during the nano-optic development.Nowadays,studies of nano-optics prefer the investigation of plasmonics in different material systems.In this article,the history of the development of near-field optics is briefly reviewed.The difficulties of conventional SNOM to achieve higher resolution are discussed.As an alternative solution,surface plasmons have shown the advantages of higher resolution,wider application,and flexible nano-optical modulation for new devices.The typical studies in different periods are introduced and characteristics of nano-optics in each stage are analyzed.In this way,the evolution progress from near-field optics to plasmonics of nano-optics research is presented.The future development of nano-optics is discussed then. 展开更多
关键词 NANO-optics near-field optics surface plasmon plasmonic modulation
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Research status and challenges in the manufacturing of IR conformal optics
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作者 Jianbo Zhao Sheng Wang +2 位作者 Chunyu Zhang Jinhu Wang Qingliang Zhao 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第10期154-172,共19页
The infrared conformal window is one of the most critical components in aircraft.Conformal windows with high performance bring low aberrations,high aerodynamic performance,reliability in extreme working environments,a... The infrared conformal window is one of the most critical components in aircraft.Conformal windows with high performance bring low aberrations,high aerodynamic performance,reliability in extreme working environments,and added value for aircraft.Through the past decades,remarkable advances have been achieved in manufacturing technologies for conformal windows,where the machining accuracy approaches the nanometer level,and the surface form becomes more complex.These advances are critical to aircraft development,and these manufacturing technologies also have significant reference values for other directions of the ultra-precision machining field.In this review,the infrared materials suitable for manufacturing conformal windows are introduced and compared with insights into their performances.The remarkable advances and concrete work accomplished by researchers are reviewed.The challenges in manufacturing conformal windows that should be faced in the future are discussed. 展开更多
关键词 Conformal optics Window and dome Infrared material Ultra-precision grinding POLISHING Measurement
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Two-photon polymerization lithography for imaging optics
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作者 Hao Wang Cheng-Feng Pan +16 位作者 Chi Li Kishan S Menghrajani Markus A Schmidt Aoling Li Fu Fan Yu Zhou Wang Zhang Hongtao Wang Parvathi Nair Suseela Nair John You En Chan Tomohiro Mori Yueqiang Hu Guangwei Hu Stefan A Maier Haoran Ren Huigao Duan Joel K W Yang 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2024年第4期21-60,共40页
Optical imaging systems have greatly extended human visual capabilities,enabling the observation and understanding of diverse phenomena.Imaging technologies span a broad spectrum of wavelengths from x-ray to radio fre... Optical imaging systems have greatly extended human visual capabilities,enabling the observation and understanding of diverse phenomena.Imaging technologies span a broad spectrum of wavelengths from x-ray to radio frequencies and impact research activities and our daily lives.Traditional glass lenses are fabricated through a series of complex processes,while polymers offer versatility and ease of production.However,modern applications often require complex lens assemblies,driving the need for miniaturization and advanced designs with micro-and nanoscale features to surpass the capabilities of traditional fabrication methods.Three-dimensional(3D)printing,or additive manufacturing,presents a solution to these challenges with benefits of rapid prototyping,customized geometries,and efficient production,particularly suited for miniaturized optical imaging devices.Various 3D printing methods have demonstrated advantages over traditional counterparts,yet challenges remain in achieving nanoscale resolutions.Two-photon polymerization lithography(TPL),a nanoscale 3D printing technique,enables the fabrication of intricate structures beyond the optical diffraction limit via the nonlinear process of two-photon absorption within liquid resin.It offers unprecedented abilities,e.g.alignment-free fabrication,micro-and nanoscale capabilities,and rapid prototyping of almost arbitrary complex 3D nanostructures.In this review,we emphasize the importance of the criteria for optical performance evaluation of imaging devices,discuss material properties relevant to TPL,fabrication techniques,and highlight the application of TPL in optical imaging.As the first panoramic review on this topic,it will equip researchers with foundational knowledge and recent advancements of TPL for imaging optics,promoting a deeper understanding of the field.By leveraging on its high-resolution capability,extensive material range,and true 3D processing,alongside advances in materials,fabrication,and design,we envisage disruptive solutions to current challenges and a promising incorporation of TPL in future optical imaging applications. 展开更多
关键词 two-photon polymerization lithography 3D printing additive manufacturing IMAGING optics and nanophotonics
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The Educational Adaptive-optics Solar Telescope at the Shanghai Astronomy Museum
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作者 Zhimao Du Qing Lin +6 位作者 Xuejun Rao Yue Zhong Jiawen Yao Hua Bao Libo Zhong Yu Liang Hui Zhang 《Astronomical Techniques and Instruments》 CSCD 2024年第3期171-178,共8页
The Educational Adaptive-optics Solar Telescope(EAST)at the Shanghai Astronomy Museum has been running routine astronomical observations since 2021.It is a 65-cm-aperture Gregorian solar telescope for scientific educa... The Educational Adaptive-optics Solar Telescope(EAST)at the Shanghai Astronomy Museum has been running routine astronomical observations since 2021.It is a 65-cm-aperture Gregorian solar telescope for scientific education,outreach,and research.The telescope system is designed in an“open”format so that the solar tower architecture can be integrated with it,and visitors can watch the observations live from inside the tower.Equipped with adaptive optics,a high-resolution imaging system,and an integral field unit spectro-imaging system,this telescope can obtain high-resolution solar images in the TiO and Hαbands,and perform spectral image reconstruction using 400 optical fibers at selected wavelengths.It can be used not only in public education and scientific outreach but also in solar physics research. 展开更多
关键词 Astronomy museum Sun observation Adaptive optics Integral field unit
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Iterative physical optics method based on efficient occlusion judgment with bounding volume hierarchy technology
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作者 Yang Su Yu-Mao Wu Jun Hu 《Journal of Electronic Science and Technology》 EI CAS CSCD 2024年第1期1-12,共12页
This paper builds a binary tree for the target based on the bounding volume hierarchy technology,thereby achieving strict acceleration of the shadow judgment process and reducing the computational complexity from the ... This paper builds a binary tree for the target based on the bounding volume hierarchy technology,thereby achieving strict acceleration of the shadow judgment process and reducing the computational complexity from the original O(N^(3))to O(N^(2)logN).Numerical results show that the proposed method is more efficient than the traditional method.It is verified in multiple examples that the proposed method can complete the convergence of the current.Moreover,the proposed method avoids the error of judging the lit-shadow relationship based on the normal vector,which is beneficial to current iteration and convergence.Compared with the brute force method,the current method can improve the simulation efficiency by 2 orders of magnitude.The proposed method is more suitable for scattering problems in electrically large cavities and complex scenarios. 展开更多
关键词 Bounding volume hierarchy Cavity scattering Iterative physical optics(IPO)
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使用均值距离与关联性标记的并行OPTICS算法 被引量:1
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作者 郑剑 余鑫 《计算机工程与应用》 CSCD 北大核心 2023年第5期232-244,共13页
针对大数据环境下传统并行密度聚类算法中存在的数据划分不合理,聚类结果准确度不高,结果受参数影响较大以及并行效率低等问题,提出一种MapReduce下使用均值距离与关联性标记的并行OPTICS算法——POMDRM-MR。算法使用一种基于维度稀疏... 针对大数据环境下传统并行密度聚类算法中存在的数据划分不合理,聚类结果准确度不高,结果受参数影响较大以及并行效率低等问题,提出一种MapReduce下使用均值距离与关联性标记的并行OPTICS算法——POMDRM-MR。算法使用一种基于维度稀疏度的减少边界点划分策略(DS-PRBP),划分数据集;针对各个分区,提出标记点排序识别簇算法(MOPTICS),构建数据点与核心点之间的关联性,并标记数据点迭代次数,在距离度量中,使用领域均值距离策略(FMD),计算数据点的领域均值距离,代替可达距离排序,输出关联性标记序列;最后结合重排序序列提取簇算法(REC),对输出序列进行二次排序并提取簇,提高算法局部聚类的准确性和稳定性;在合并全局簇时,算法提出边界密度筛选策略(BD-FLC),计算筛选密度相近局部簇;又基于n叉树的并集型合并与MapReduce模型,提出并行局部簇合并算法(MCNT-MR),加快局部簇收敛,并行合并局部簇,提升全局簇合并效率。对照实验表明,POMDRM-MR算法聚类效果更佳,且在大规模数据集下算法的并行化性能更好。 展开更多
关键词 大数据 密度聚类 MAPREDUCE optics PRBP
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基于D-OPTICS算法的网约车载客热点区域挖掘 被引量:2
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作者 王璐瑶 邬岚 +1 位作者 杨晟 朱兴贝 《北京航空航天大学学报》 EI CAS CSCD 北大核心 2023年第11期3124-3131,共8页
为准确分析网约车载客高需求热点区域,考虑载客热点聚类中车辆行驶距离的约束,采用结合Dijkstra寻路算法的OPTICS算法,提出寻路密度OPTICS(D-OPTICS)算法。DOPTICS算法利用车辆轨迹数据进行空间聚类研究分析载客热点区域。通过道路网络... 为准确分析网约车载客高需求热点区域,考虑载客热点聚类中车辆行驶距离的约束,采用结合Dijkstra寻路算法的OPTICS算法,提出寻路密度OPTICS(D-OPTICS)算法。DOPTICS算法利用车辆轨迹数据进行空间聚类研究分析载客热点区域。通过道路网络拓扑结构提取各路段节点,采用Dijkstra算法进行寻路并以路段为单位提取邻域范围内载客点进行聚类。将成都市网约车轨迹数据进行热点区域的挖掘和分析。与传统OPTICS算法相比,所提算法考虑了道路距离的约束,提高了载客热点聚类稳定性和精度,获取的载客热点区域更贴合实际情况。 展开更多
关键词 数据挖掘 载客热点 optics算法 车辆轨迹 DIJKSTRA算法
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Plasma optics:A perspective for high-power coherent light generation and manipulation 被引量:2
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作者 C.Riconda S.Weber 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2023年第2期1-5,共5页
Over the last two decades,the importance of fully ionized plasmas for the controlled manipulation of high-power coherent light has increased considerably.Many ideas have been put forward on how to control or change th... Over the last two decades,the importance of fully ionized plasmas for the controlled manipulation of high-power coherent light has increased considerably.Many ideas have been put forward on how to control or change the properties of laser pulses such as their frequency,spectrum,intensity,and polarization.The corresponding interaction with a plasma can take place either in a self-organizing way or by prior tailoring.Considerable work has been done in theoretical studies and in simulations,but at present there is a backlog of demand for experimental veri-fication and the associated detailed characterization of plasma-optical elements.Existing proof-of-principle experiments need to be pushed to higher power levels.There is little doubt that plasmas have huge potential for future use in high-power optics.This introduction to the special issue of Matter and Radiation at Extremes devoted to plasma optics sets the framework,gives a short historical overview,and briefly describes the various articles in this collection. 展开更多
关键词 power optics COHERENT
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Development of multi-band and high-speed visible endoscope diagnostic on EAST with catadioptric optics
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作者 韩效锋 杨建华 +4 位作者 严海龙 臧庆 扈嘉辉 孙鹏军 杨晓飞 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第5期207-213,共7页
A new multi-band and high-speed endoscope diagnostic for the observation of visible light has been successfully developed on the Experimental Advanced Superconducting Tokamak.The mirror with an aperture is designed at... A new multi-band and high-speed endoscope diagnostic for the observation of visible light has been successfully developed on the Experimental Advanced Superconducting Tokamak.The mirror with an aperture is designed at the head of the optical system.Based on two dichroic mirrors,the system is divided into three imaging mirror groups with different bands,i.e.B(380-500 nm),G(500-580 nm)and R(580-750 nm)bands,and its focal length is 16 mm with a relatively large aperture of D/f=1:4.The spatial resolution is less than 5 mm near the object distance of 1750 mm with the camera NAC ACS-1 M60.This optical system will be used to contrastively study both the spatial distribution and time evolution of different impurities in the same field of view.The experimental results confirm that it can be applied to the recognition of plasma boundary and related physical research. 展开更多
关键词 visible camera diagnostic multi-band optics endoscope optics
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Deep learning-based inpainting of saturation artifacts in optical coherence tomography images 被引量:2
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作者 Muyun Hu Zhuoqun Yuan +2 位作者 Di Yang Jingzhu Zhao Yanmei Liang 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2024年第3期1-10,共10页
Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts ... Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts and restore texture completely in OCT images.We proposed a deep learning-based inpainting method of saturation artifacts in this paper.The generation mechanism of saturation artifacts was analyzed,and experimental and simulated datasets were built based on the mechanism.Enhanced super-resolution generative adversarial networks were trained by the clear–saturated phantom image pairs.The perfect reconstructed results of experimental zebrafish and thyroid OCT images proved its feasibility,strong generalization,and robustness. 展开更多
关键词 optical coherence tomography saturation artifacts deep learning image inpainting.
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Multi-dimensional multiplexing optical secret sharing framework with cascaded liquid crystal holograms 被引量:2
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作者 Keyao Li Yiming Wang +6 位作者 Dapu Pi Baoli Li Haitao Luan Xinyuan Fang Peng Chen Yanqing Lu Min Gu 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2024年第1期28-35,共8页
Secret sharing is a promising technology for information encryption by splitting the secret information into different shares.However,the traditional scheme suffers from information leakage in decryption process since... Secret sharing is a promising technology for information encryption by splitting the secret information into different shares.However,the traditional scheme suffers from information leakage in decryption process since the amount of available information channels is limited.Herein,we propose and demonstrate an optical secret sharing framework based on the multi-dimensional multiplexing liquid crystal(LC)holograms.The LC holograms are used as spatially separated shares to carry secret images.The polarization of the incident light and the distance between different shares are served as secret keys,which can significantly improve the information security and capacity.Besides,the decryption condition is also restricted by the applied external voltage due to the variant diffraction efficiency,which further increases the information security.In implementation,an artificial neural network(ANN)model is developed to carefully design the phase distribution of each LC hologram.With the advantage of high security,high capacity and simple configuration,our optical secret sharing framework has great potentials in optical encryption and dynamic holographic display. 展开更多
关键词 holographic encryption optical secret sharing cascaded liquid crystal hologram multi-dimensional multiplexing
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Coherent optical frequency transfer via 972-km fiber link 被引量:1
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作者 邓雪 张翔 +8 位作者 臧琦 焦东东 王丹 刘杰 高静 许冠军 董瑞芳 刘涛 张首刚 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期277-282,共6页
We demonstrate coherent optical frequency dissemination over a distance of 972 km by cascading two spans where the phase noise is passively compensated for.Instead of employing a phase discriminator and a phase lockin... We demonstrate coherent optical frequency dissemination over a distance of 972 km by cascading two spans where the phase noise is passively compensated for.Instead of employing a phase discriminator and a phase locking loop in the conventional active phase control scheme,the passive phase noise cancellation is realized by feeding double-trip beat-note frequency to the driver of the acoustic optical modulator at the local site.This passive scheme exhibits fine robustness and reliability,making it suitable for long-distance and noisy fiber links.An optical regeneration station is used in the link for signal amplification and cascaded transmission.The phase noise cancellation and transfer instability of the 972-km link is investigated,and transfer instability of 1.1×10^(-19)at 10^(4)s is achieved.This work provides a promising method for realizing optical frequency distribution over thousands of kilometers by using fiber links. 展开更多
关键词 optical frequency transfer fiber link phase noise cancellation
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Fiber optic monitoring of an anti-slide pile in a retrogressive landslide 被引量:3
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作者 Lei Zhang Honghu Zhu +1 位作者 Heming Han Bin Shi 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期333-343,共11页
Anti-slide piles are one of the most important reinforcement structures against landslides,and evalu-ating the working conditions is of great significance for landslide mitigation.The widely adopted analytical methods... Anti-slide piles are one of the most important reinforcement structures against landslides,and evalu-ating the working conditions is of great significance for landslide mitigation.The widely adopted analytical methods of pile internal forces include cantilever beam method and elastic foundation beam method.However,due to many assumptions involved in calculation,the analytical models cannot be fully applicable to complex site situations,e.g.landslides with multi-sliding surfaces and pile-soil interface separation as discussed herein.In view of this,the combination of distributed fiber optic sensing(DFOS)and strain-internal force conversion methods was proposed to evaluate the working conditions of an anti-sliding pile in a typical retrogressive landslide in the Three Gorges reservoir area,China.Brillouin optical time domain reflectometry(BOTDR)was utilized to monitor the strain distri-bution along the pile.Next,by analyzing the relative deformation between the pile and its adjacent inclinometer,the pile-soil interface separation was profiled.Finally,the internal forces of the anti-slide pile were derived based on the strain-internal force conversion method.According to the ratio of calculated internal forces to the design values,the working conditions of the anti-slide pile could be evaluated.The results demonstrated that the proposed method could reveal the deformation pattern of the anti-slide pile system,and can quantitatively evaluate its working conditions. 展开更多
关键词 Anti-slide pile Multi-sliding surface Pile-soil interface Brillouin optical time domain reflectometry (BOTDR) Geotechnical monitoring Reservoir landslide
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Biomarkers for neuromyelitis optica:a visual analysis of emerging research trends 被引量:3
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作者 Xiangjun Li Jiandong Zhang +4 位作者 Siqi Zhang Shengling Shi Yi’an Lu Ying Leng Chunyan Li 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第12期2735-2749,共15页
Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis.Over the past 20 years,the search for biomarke rs for neuromyelitis optica has been ongo... Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis.Over the past 20 years,the search for biomarke rs for neuromyelitis optica has been ongoing.Here,we used a bibliometric approach to analyze the main research focus in the field of biomarkers for neuromyelitis optica.Research in this area is consistently increasing,with China and the United States leading the way on the number of studies conducted.The Mayo Clinic is a highly reputable institution in the United States,and was identified as the most authoritative institution in this field.Furthermore,Professor Wingerchuk from the Mayo Clinic was the most authoritative expe rt in this field.Keyword analysis revealed that the terms "neuro myelitis optica"(261 times), "multiple sclerosis"(220 times), "neuromyelitis optica spectrum disorder"(132 times), "aquaporin4"(99 times),and "optical neuritis"(87 times) were the most frequently used keywords in literature related to this field.Comprehensive analysis of the classical literature showed that the majority of publications provide conclusive research evidence supporting the use of aquaporin-4-IgG and neuromyelitis optica-IgG to effectively diagnose and differentiate neuromyelitis optica from multiple sclerosis.Furthermore,aquaporin-4-IgG has emerged as a highly specific diagnostic biomarker for neuromyelitis optica spectrum disorder.Myelin oligodendrocyte glycoprotein-IgG is a diagnostic biomarke r for myelin oligodendrocyte glycoprotein antibody-associated disease.Recent biomarkers for neuromyelitis optica in clude cerebrospinal fluid immunological biomarkers such as glial fibrillary acidic protein,serum astrocyte damage biomarkers like FAM19A5,serum albumin,and gammaaminobutyric acid.The latest prospective clinical trials are exploring the potential of these biomarkers.Preliminary results indicate that glial fibrillary acidic protein is emerging as a promising candidate biomarker for neuromyelitis optica spectrum disorder.The ultimate goal of future research is to identify non-invasive biomarkers with high sensitivity,specificity,and safety for the accurate diagnosis of neuro myelitis optica. 展开更多
关键词 AQUAPORIN-4 AUTOANTIBODY multiple sclerosis myelin oligodendrocyte glycoprotein antibody-associated disease neuromyelitis optica neuromyelitis optica spectrum disorder optical coherence tomography
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One-year results for myopia control of orthokeratology with different back optic zone diameters: a randomized trial using a novel multispectral-based topographer 被引量:1
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作者 Wen-Ting Tang Xiang-Ning Luo +4 位作者 Wen-Jing Zhao Jia Liao Xin-Yue Xu Hui-Dan Zhang Li Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第2期324-330,共7页
AIM:To present the 1-year results of a prospective cohort study investigating the efficacy,potential mechanism,and safety of orthokeratology(ortho-k)with different back optic zone diameters(BOZD)for myopia control in ... AIM:To present the 1-year results of a prospective cohort study investigating the efficacy,potential mechanism,and safety of orthokeratology(ortho-k)with different back optic zone diameters(BOZD)for myopia control in children.METHODS:This randomized clinical study was performed between Dec.2020 and Dec.2021.Participants were randomly assigned to three groups wearing ortho-k:5 mm BOZD(5-MM group),5.5 mm BOZD(5.5-MM group),and 6 mm BOZD(6-MM group).The 1-year data were recorded,including axial length,relative peripheral refraction(RPR,measured by multispectral refractive topography,MRT),and visual quality.The contrast sensitivity(CS)was evaluated by CSV-1000 instrument with spatial frequencies of 3,6,12,and 18 cycles/degree(c/d);the corneal higher-order aberrations(HOAs)were measured by iTrace aberration analyzer.The one-way ANOVA was performed to assess the differences between the three groups.The correlation between the change in AL and RPR was calculated by Pearson’s correlation coefficient.RESULTS:The 1-year results of 20,21,and 21 subjects in the 5-MM,5.5-MM,and 6-MM groups,respectively,were presented.There were no statistical differences in baseline age,sex,or ocular parameters between the three groups(all P>0.05).At the 1-year visit,the 5-MM group had lower axial elongation than the 6-MM group(0.07±0.09 vs 0.18±0.11 mm,P=0.001).The 5-MM group had more myopic total RPR(TRPR,P=0.014),with RPR in the 15°–30°(RPR 15–30,P=0.015),30°–45°(RPR 30–45,P=0.011),temporal(RPR-T,P=0.008),and nasal area(RPR-N,P<0.001)than the 6-MM group.RPR 15–30 in the 5.5-MM group was more myopic than that in the 6-MM group(P=0.002),and RPR-N in the 5-MM group was more myopic than that in the 5.5-MM group(P<0.001).There were positive correlations between the axial elongation and the change in TRPR(r=0.756,P<0.001),RPR 15–30(r=0.364,P=0.004),RPR 30–45(r=0.306,P=0.016),and RPR-N(r=0.253,P=0.047).The CS decreased at 3 c/d(P<0.001),and the corneal HOAs increased in the 5-MM group(P=0.030).CONCLUSION:Ortho-k with 5 mm BOZD can control myopia progression more effectively.The mechanism may be associated with greater myopic shifts in RPR. 展开更多
关键词 relative peripheral refraction ORTHOKERATOLOGY MYOPIA back optic zone diameter axial length multispectral refractive topography
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Special issue on digital and intelligent optics
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作者 Guangwei Hu Junsuk Rho 《Opto-Electronic Science》 2023年第11期1-3,共3页
Innovations in artificial intelligence have revolutionized various areas,especially optics.The rapid development of novel optoelectronic devices at nanoscale has exhibited the multiple functionalities,high integration... Innovations in artificial intelligence have revolutionized various areas,especially optics.The rapid development of novel optoelectronic devices at nanoscale has exhibited the multiple functionalities,high integration,compactness,fast modulation and scalability,showcasing new breakthroughs of digital optics and optoelectronic processors for intelligent computations. 展开更多
关键词 optics BREAKTHROUGH OPTOELECTRONIC
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