A compact annular-radial-orifice flow magnetorheological(MR)valve was developed to investigate the effects of radial resistance gap on pressure drop.The fluid flow paths of this proposed MR valve consist of a single a...A compact annular-radial-orifice flow magnetorheological(MR)valve was developed to investigate the effects of radial resistance gap on pressure drop.The fluid flow paths of this proposed MR valve consist of a single annular flow channel,a single radial flow channel and an orifice flow channel through structure design.The finite element modelling and simulation analysis of the MR valve was carried out using ANSYS/Emag software to investigate the changes of the magnetic flux density and yield stress along the fluid flow paths under the four different radial resistance gaps.Moreover,the experimental tests were also conducted to evaluate the pressure drop,showing that the proposed MR valve has significantly improved its pressure drop at 0.5 mm width of the radial resistance gap when the annular resistance gap is fixed at 1 mm.展开更多
The static dent resistance performance of the aluminum alloy double-curved panel formed using viscous pressure forming (VPF)was studied by finite element analysis,which mainly considers the forming process conditions....The static dent resistance performance of the aluminum alloy double-curved panel formed using viscous pressure forming (VPF)was studied by finite element analysis,which mainly considers the forming process conditions.The whole simulation consisting of three stages,i.e.,forming,spring-back and static dent resistance,was carried out continuously using the finite element code ANSYS.The influence of blank holder pressure(BHP)and the drawbead on the stiffness and the static dent resistance of the panels formed using VPF was analyzed.The results show that the adequate setting of the drawbead can increase the plastic deformation of the double-curved panel,which is beneficial to the initial stiffness and the static dent resistance.There is an optimum BHP range for the stiffness and the static dent resistance.展开更多
The structure and working principle of a self-deigned high pressure electronic pneumatic pressure reducing valve (EPPRV) with slide pilot are introduced.The resistance value formulas and the relationship between the r...The structure and working principle of a self-deigned high pressure electronic pneumatic pressure reducing valve (EPPRV) with slide pilot are introduced.The resistance value formulas and the relationship between the resistance and pressure of three typical pneumatic resistances are obtained.Then,the method of static characteristics analysis only considering pneumatic resistances is proposed,the resistance network from gas supply to load is built up,and the mathematical model is derived from the flow rate formulas and flow conservation equations,with the compressibility of high pressure gas and temperature drop during the expansion considered in the model.Finally,the pilot spool displacement of 1.5 mm at an output pressure of 15MPa and the enlarging operating stroke of the pilot spool are taken as optimization targets,and the optimization is carried out based on genetic algorithm and the model mentioned above.The results show that the static characteristics of the EPPRV are significantly improved.The idea of static characteristics analysis and optimization based on pneumatic resistance network is valuable for the design of pneumatic components or system.展开更多
Recently,magnesium and its alloys have attracted more and more attention as promising implant materials due to their excellent properties such as good biocompatibility,biodegradation,non-toxicity and comparable mechan...Recently,magnesium and its alloys have attracted more and more attention as promising implant materials due to their excellent properties such as good biocompatibility,biodegradation,non-toxicity and comparable mechanical properties with natural bone.They can be gradually degraded and absorbed so as to avoid the second surgery for implants removal after the tissues are healed completely.In addition,they are also able to prevent the stress shielding effect in human body environment because of the density,elastic modulus and yield strength of magnesium closer to the bone.Unfortunately,the high corrosion rate which causes early mechanical failure of the implants in physiological environment limits the widespread use of magnesium alloys for clinical application in biology.And the high corrosion process usually causes huge hydrogen evolution and alkalinization,resulting in problems against the implants as well as the surrounding tissues.In order to enhance the corrosion resistance of magnesium alloys,in this study,the ZEK100 magnesium alloy was pre-deformed with a highpressure torsion(HPT)process and then fabricated hydroxyapatite(HA)coatings with different contents of Mg(OH)2 nanopowder via hydrothermal method.The specimens were characterized by scanning electron microscope(SEM)and X-ray diffraction(XRD).At the same time,prior and after the HPT procedure,the metallography,microhardness and tensile tests of specimens were characterized.Meanwhile,the corrosion behavior of the specimens was evaluated by electrochemical impedance spectroscopy(EIS)and hydrogen evolution tests.And the interface bonding strength of the HA coating on the magnesium alloy substrate was evaluated by a tape adhesion test/scratch test.Results showed that HPT processing refined the grain size and introduced a great number of twins,resulting in the enhancement of microhardness and Young’s modulus of ZEK100 magnesium alloy,but hardness values at the edge were higher than those at the center due to the uneven shear strain.At the same conditions,the HA coating on HPT-ZEK was denser,thicker than that on ZEK sample and the crystal sizes of HA were smaller on HPT-ZEK.These were attributed to fine,uniform distributed secondary phases and lots of fine grains,twins,grain boundaries in HPT-ZEK substrates which can provide more nucleation sites for the HA crystal.In terms of the amount of Mg(OH)2 nanopowder,Mg(OH)2 nanopowder significantly influenced the microstructure and thickness of the HA coating.And at a 0.3 mg/mL content of Mg(OH)2 nanopowder,there was the densest,thickest HA coating on magnesium alloys,and the crystal size of HA was minimum.Specifically,the HA coating thickness on ZEK-03(0.3 mg/mL Mg(OH)2 nanopowder)was 1.8 times of that on ZEK-00(0 mg/mL Mg(OH)2 nanopowder),while the HA coating thickness on HPT-03 was 2.6 times of that on ZEK-00.And the adhesion strength of HA coating on HPT-03 substrate was better than that on ZEK-03.In addition,HPT technology and surface modification by HA coating simultaneously increased the corrosion resistance of ZEK100 magnesium alloy and the corrosion of HPT-ZEK samples occurred in a more uniform manner,while it was pitting on the surface of ZEK100 magnesium alloy.Therefore,there was the best corrosion resistance on HPT-03 sample,which could promote the application of magnesium alloys in biomedical fields.展开更多
The association between fasting plasma ghrelin levels and insulin resistance and blood pressure(BP) in octogenarians was investigated in this study.A total of 487 unrelated octogenarians(including 203 men and 284 wome...The association between fasting plasma ghrelin levels and insulin resistance and blood pressure(BP) in octogenarians was investigated in this study.A total of 487 unrelated octogenarians(including 203 men and 284 women) were enrolled in this cross-sectional study at the Healthy Care Center of Shanghai East Hospital,Tongji University,China,from October 2008 to April 2009.Plasma ghrelin was determined by using the enzyme linked immunosorbent assay(ELISA).Insulin sensitivity was assessed using the homeostasis model of assessment-insulin resistance(HOMA-IR).The age of the participants ranged from 80 to 89 years(mean=83.9±4.8 years) with a body mass index(BMI) of 25.3±4.9 kg/m2.Plasma ghrelin level[w1]s were 20.94±5.34 μg/L,being 20.89±5.53 μg/L in men and 21.38±3.73 μg/L in women respectively.Plasma ghrelin was not associated with systolic(P=0.981) or diastolic(P=0.724) BP,waist circumference(P=0.278),fasting insulin(P=0.246),fasting blood glucose(FBG)(P=0.693) and HOMA-IR(P=0.232).In the control cohort,no significant differences in plasma ghrelin were found between genders(P=0.489),and among subjects with hypertension(BP>140/90 mmHg)(P=0.284) and type 2 diabetes(P=0.776).In conclusion,fasting plasma ghrelin levels are not directly correlated with insulin resistance and BP among octogenarians.展开更多
The in situ electrical resistance and transport activation energies of solid C60 fullerene have been measured under high pressure up to 25 GPa in the temperature range of 300-423 K by using a designed diamond anvil ce...The in situ electrical resistance and transport activation energies of solid C60 fullerene have been measured under high pressure up to 25 GPa in the temperature range of 300-423 K by using a designed diamond anvil cell. In the experiment, four parts of boron-doped diamond films fabricated on one anvil were used as electrical measurement probes and a W-Ta thin film thermocouple which was integrated on the other diamond anvil was used to measure the temperature. The current results indicate that the measured high-pressure resistances are bigger than those reported before at the same pressure and there is no pressure-independent resistance increase before 8 GPa. From the temperature dependence of the resistivity, the C60 behaviors as a semiconductor and the activation energies of the cubic C60 fullerene are 0,49, 0.43, and 0.36 eV at 13, 15, and 19 GPa, respectively.展开更多
Monitoring the prevalence of antimicrobial resistance genes(ARGs)is vital for addressing the global crisis of antibiotic-resistant bacterial infections.Despite its importance,the characterization of ARGs and microbiom...Monitoring the prevalence of antimicrobial resistance genes(ARGs)is vital for addressing the global crisis of antibiotic-resistant bacterial infections.Despite its importance,the characterization of ARGs and microbiome structures,as well as the identification of indicators for routine ARG monitoring in pig farms,are still lacking,particularly concerning variations in antimicrobial exposure in different countries or regions.Here,metagenomics and random forest machine learning were used to elucidate the ARG profiles,microbiome structures,and ARG contamination indicators in pig manure under different antimicrobial pressures between China and Europe.Results showed that Chinese pigs exposed to high-level antimicrobials exhibited higher total and plasmid-mediated ARG abundances compared to those in European pigs(P<0.05).ANT(6)-Ib,APH(3')-IIIa,and tet(40)were identified as shared core ARGs between the two pig populations.Furthermore,the core ARGs identified in pig populations were correlated with those found in human populations within the same geographical regions.Lactobacillus and Prevotella were identified as the dominant genera in the core microbiomes of Chinese and European pigs,respectively.Forty ARG markers and 43 biomarkers were able to differentiate between the Chinese and European pig manure samples with accuracies of 100%and 98.7%,respectively.Indicators for assessing ARG contamination in Chinese and European pigs also achieved high accuracy(r=0.72-0.88).Escherichia flexneri in both Chinese and European pig populations carried between 21 and 37 ARGs.The results of this study emphasize the importance of global collaboration in reducing antimicrobial resistance risk and provide validated indicators for evaluating the risk of ARG contamination in pig farms.展开更多
Objectives To investigate clinical characteristics, target organ damage, and the associated risk factors of the patients aged ≥ 80 yearswith true resistant hypertension (RH). Methods Patients aged ≥ 80 years with ...Objectives To investigate clinical characteristics, target organ damage, and the associated risk factors of the patients aged ≥ 80 yearswith true resistant hypertension (RH). Methods Patients aged ≥ 80 years with hypertension (n = 1163) were included in this study. Theincluded participants attended a structured clinical examination and an evaluation of RH was carried out. The prevalence, clinical characteristicsand target organ damage of patients with RH were assessed. The associated clinical risk factors were analyzed by using logistic regression.Results The prevalence of RH diagnosis by 24-h ambulatory blood pressure monitoring assessment was 21.15%. End-diastolic left ven-tricular internal dimension, left ventricular mass index as well as prevalence of left ventricular hypertrophy were significantly greater in pa-tients with RH than in control group. The common carotid artery intimal media thickness, carotid walls thickness, common carotid arterydiameter and relative wall thickness were significant greater in RH group than in control. A relatively higher level of creatinine, estimatedglomerular filtration rate, microalbuminuria and retinal changes was found in RIt group than in control. A multivariate analysis showed thatpatients with a history of diabetes, higher body mass index (BMI) and lipid profiles were independent risk factors of RH. Conclusions Theprevalence of RH in patients aged ≥ 80 years was within the range of reported rates of the general population. Subjects with RH diagnosisshowed a higher occurrence of target organ damage than patients with well controlled blood pressure. Patients with diabetes, higher BMI andserum lipid profiles were independent risk factors for RH in patients aged ≥ 80 years.展开更多
The FW process is a prefect method of manufacturing FRP composite air vessel resisting high pressure and aerial press vessel.In this paper FW pattern of FRP composite air vessel resisting high pressure was analyzed in...The FW process is a prefect method of manufacturing FRP composite air vessel resisting high pressure and aerial press vessel.In this paper FW pattern of FRP composite air vessel resisting high pressure was analyzed in a nutshell.The stability of FW patterns on end head is very sensitive to changing of pattern parameter.Consequently,its FW pattern was based on geodesic track.The FW angles and on equators depend on the dimension of end part and the condition of geodesic FW.Generally speaking, the polar holes of rocket engine shell are disproportional.Therefore,the FW angles of the shell column are changeable.The feasi- bility of nongeodesic FW of the shell column was discussed in this paper.Furthermore,it expounded the indispensable condition be- tween the length of shell column and the FW friction coefficient.At the same time,the general mathematic models of the movement control of nongeodesic FW were deduced.展开更多
Nematic order and its fluctuations have been widely found in iron-based superconductors. Above the nematic order transition temperature, the resistivity shows a linear relationship with the uniaxial pressure or strain...Nematic order and its fluctuations have been widely found in iron-based superconductors. Above the nematic order transition temperature, the resistivity shows a linear relationship with the uniaxial pressure or strain along the nematic direction and the normalized slope is thought to be associated with nematic susceptibility. Here we systematically studied the uniaxial pressure dependence of the resistivity in Sr1 _xBaxFel.97Nio.03As2, where nonlinear behaviors are observed near the nematic transition temperature. We show that it can be well explained by the Landau theory for the second-order phase transitions considering that the external field is not zero. The effect of the coupling between the isotropic and nematic channels is shown to be negligible. Moreover, our results suggest that the nature of the magnetic and nematic transitions in Srl xBaxFe2As2 is determined by the strength of the magnetic-elastic coupling.展开更多
Sampling study is an effective exploration method, but the most extreme environments of hydrothermal vents pose considerable engineering challenges for sampling hydrothermal fluids. Moreover, traditional sampler syste...Sampling study is an effective exploration method, but the most extreme environments of hydrothermal vents pose considerable engineering challenges for sampling hydrothermal fluids. Moreover, traditional sampler systems with sample valves have difficulty in maintaining samples in situ pressure. However, decompression changes have effect on microorganisms sensitive to such stresses. To address the technical difficulty of collecting samples from hydrothermal vents, a new bidirectional high pressure-resistant sample valve with balanced poppet was designed. The sample valve utilizes a soft high performance plastic "PEEK" as poppet. The poppet with inapposite dimension is prone to occur to plastic deformation or rupture for high working pressure in experiments. To address this issue, based on the fmite element model, simulated results on stress distribution of the poppet with different structure parameters and preload spring force were obtained. The static axial deformations on top of the poppet were experimented. The simulated results agree with the experimental results. The new sample valve seals well and it can withstand high working pressure.展开更多
Flexible piezoresistive pressure sensors can offer convenient detection of mechanical deformations for wearable electronics.Previous studies of flexible piezoresistive pressure sensors focus on the sensitivity but the...Flexible piezoresistive pressure sensors can offer convenient detection of mechanical deformations for wearable electronics.Previous studies of flexible piezoresistive pressure sensors focus on the sensitivity but the low-cost and self-powered sensors remain a challenge due to the deviation of resistance signal acquisition caused by thermoelectric voltage.Here,piezoresistive pressure sensors with ultralow Seebeck coefficient of-0.72μV/K based on carbon nanotubes(CNTs)/polyethyleneimine(PEI)/melamine(CPM)sponge are reported.Due to the diminished Seebeck effect,the CPM sponge pressure sensors successfully reduce the deviation to 18.75%and can keep stable sensitivity and resistance change under a very low working voltage and change temperature environment.The stable properties of the sensors make them successful to work for real-time sensing in self-powered wearable electronics.展开更多
In this research,an atmospheric-pressure air plasma is used to inactivate the multidrug-resistant Acinetobacter baumannii in liquid.The efficacy of the air plasma on bacterial deactivation and the cytobiological varia...In this research,an atmospheric-pressure air plasma is used to inactivate the multidrug-resistant Acinetobacter baumannii in liquid.The efficacy of the air plasma on bacterial deactivation and the cytobiological variations after the plasma treatment are investigated.According to colony forming units,nearly all the bacteria(6-log) are inactivated after 10 min of air plasma treatment.However,7% of the bacteria enter a viable but non-culturable state detected by the resazurin based assay during the same period of plasma exposure.Meanwhile,86% of the bacteria lose their membrane integrity in the light of SYTO 9/PI staining assay.The morphological changes in the cells are examined by scanning electron microscopy and bacteria with morphological changes are rare after plasma exposure in the liquid.The concentrations of the long-living RS,such as H2O2,NO3^- and O3,in liquid induced by plasma treatment are measured,and they increase with plasma treatment time.The changes of the intracellular ROS may be related to cell death,which may be attributed to oxidative stress and other damage effects induced by RS plasma generated in liquid.The rapid and effective bacteria inactivation may stem from the RS in the liquid generated by plasma and air plasmas may become a valuable therapy in the treatment of infected wounds.展开更多
In exploration for tight oil, the content and saturation of hydrocarbon in the tight reservoir is a key factor for evaluating the reserve. Therefore, it is necessary to study the geological history of hydrocarbon accu...In exploration for tight oil, the content and saturation of hydrocarbon in the tight reservoir is a key factor for evaluating the reserve. Therefore, it is necessary to study the geological history of hydrocarbon accumulation and the tight oil charging process. However, kinetic models used for petroleum development are not applicable for petroleum exploration. In this study, a static resistance model[ is proposed after analyzing resistances in ultra-slow flow in porous media. Using this model, the disco^atinuous pattern of oil charging is reproduced through incompressible Navier-Stokes equations, the phase field method and the finite element method. This study also explains macroscopic percolation behavior with microscopic flow mechanisms and discusses some issues in ultra-slow flow in a micro/nano pore-throat network. The resistance analysis reveals that capillary resistance and dissipation resistance are dominant factors in the mechanism of oil accumulation in tight reservoirs. Numerical simulations show that pressure thresholds exist and result in discontinuous oil charging. Generally, it is proven that the static model is more applicable than kinetic models in describing oil accumulation in tight reservoirs.展开更多
PolycrystaUine SnO2 thin films were deposited on sapphire substrates at 450℃ under different ambient oxygen pressures by pulsed laser deposition technique. The effect of ambient oxygen pressure on the structural, opt...PolycrystaUine SnO2 thin films were deposited on sapphire substrates at 450℃ under different ambient oxygen pressures by pulsed laser deposition technique. The effect of ambient oxygen pressure on the structural, optical and electrical properties of SnO2 thin films was studied. X-my diffraction and Hall measurements show that increasing the ambient oxygen pressure can improve crystallization of the films and decrease resistivity of the films. A violet emission peak centered at 409 nm was observed from photoluminescence measurements for SnO2 films under deposition ambient oxygen pressure above 5 Pa, which is related to the improvement of crystalline of the films.展开更多
The desensitization degree of emulsion explosives (EE) was calculated with the peak pressure of explosion shock waves tested in water. To an explosive, the less the desensitization degree, the better the compression...The desensitization degree of emulsion explosives (EE) was calculated with the peak pressure of explosion shock waves tested in water. To an explosive, the less the desensitization degree, the better the compression resistance, so the compression resistance of an explosive can be compared and analyzed quantificationally with the desensitization degree. The influence of an emulsifier on the pressure desensitization of EE was studied, including the content and category of emulsifiers. Three kinds of emulsifiers (Span-80, compound emulsifier, and T-152) were used in the tests. The experimental results show that both the content and category of emulsifiers make a great effect on the pressure desensitization of EE. The desensitization degree of EE reduces with the emulsifier content being increased, but there is an optimal content of an emulsifier for the compression resistance of EE. While the content of Span-80 reaches 4wt%, the desensitization degree of EE becomes a minimal value, and augments somewhat if the emulsifier content is increased more. That is to say, the compression resistance of EE becomes the highest while the content of Span-80 is 4wt%, and the compression resistance will decline if the content of Span-80 is increased more. The compression resistance of the explosive emulsified by compound emulsifier is the highest among all the explosives, when the content of the whole components and manufacturing engineering are kept invariable.展开更多
The pressure characteristics inside single loop oscillating heat pipe (OHP) having 4.5 mm inner diameter copper tube with the loop height of 440 mm were addressed. Distilled water was used as working fluid inside th...The pressure characteristics inside single loop oscillating heat pipe (OHP) having 4.5 mm inner diameter copper tube with the loop height of 440 mm were addressed. Distilled water was used as working fluid inside the OHP with different filling ratios of 40%, 60% and 80% of total inside volume. Experimental results show that the thermal characteristics are significantly inter-related with pressure fluctuations as well as pressure frequency. And the pressure frequency also depends upon the evaporator temperature that is maintained in the range of 60-96 ℃. Piezoresistive absolute pressure sensor (Model-Kistler 4045A5) was used to take data. The investigation shows that the filling ratio of 60% gives the highest inside pressure magnitude at maximum number of pressure frequency at any of set evaporator temperature and the lowest heat flow resistance is achieved at 60% filling ratio.展开更多
AIM: To define the corneal hysteresis(CH), corneal resistance factor(CRF), Goldmann-correlated intraocular pressure(IOPg) and corneal compensated intraocular pressure(IOPcc) prior to and following coaxial micro-incisi...AIM: To define the corneal hysteresis(CH), corneal resistance factor(CRF), Goldmann-correlated intraocular pressure(IOPg) and corneal compensated intraocular pressure(IOPcc) prior to and following coaxial micro-incision phacoemulsification in patients with corneal astigmatism. METHODS: Of 97 patients with cataracts were enrolled in the study. Group 1 included patients with corneal astigmatism(K1-K2) values of K1-K2<+1.0 D, and group 2 with values of K1-K2 ≥+1.0 D and ≤+2.25 D. Coaxial micro-incision phacoemulsification of a corneal incision of 2.0 mm with intraocular lens(IOL) implantation was performed. CH, CRF, IOPg, IOPcc, waveform score(WS) were measured preoperatively and one week, one month postoperatively using an Ocular Response Analyzer. Axial length(AXL) was calculated by Tomey Optical Biometer OA 2000.RESULTS: Group 1 consisted of 51 patients with mean corneal astigmatism value of +0.49±0.25 D. Group 2 included 46 patients with astigmatism of +1.43±0.43 D. In group 1, CRF(t=2.68, P<0.05), CH(t=2.64, P<0.05) and WS(t=3.51, P<0.05) were significantly lower one week postoperatively, when compared to the preoperative values. CRF significantly decreased(t=3.61, P<0.05) when measured one month following the surgery. In group 2 CH(t=5.92, P<0.05), and WS(t=3.96, P<0.05) were significantly lowered one week after cataract surgery. Moreover, we observed a significant decrease in IOPg(t=2.24, P<0.05), CRF(t=5.05, P<0.05) and CH(t=2.31, P<0.05) one month after phacoemulsification. There was no statistically significant(t=-0.83, P=0.41) difference in AXL between study groups.CONCLUSION: CRF, CH and IOPg are reduced in patients with preoperative corneal astigmatism equal or higher than +1.0 D and lower than +2.25 D. Hence, bias of IOPg measurement in these patients may cause underestimation of the real IOP both before and after cataract surgery. The measurement of IOPcc allows the precise assessment of IOP pre-and postoperatively, independently on corneal astigmatism, CH and CRF values.展开更多
The Chinese fir wood was impregnated using a cyclic increasingpressure method(CIPM)with phenolic prepolymers as the impregnating modifier.Unmodified Chinese fir and progressive increasing-pressure method(PIPM)impregn...The Chinese fir wood was impregnated using a cyclic increasingpressure method(CIPM)with phenolic prepolymers as the impregnating modifier.Unmodified Chinese fir and progressive increasing-pressure method(PIPM)impregnated Chinese fir were used as reference samples and were compared and analyzed.The product’s chemical structure,internal morphology,crystal structure,and heat resistance were characterized.The transversal and longitudinal sections showed better filling effects,so that it bore greater external loading and reduced the water storage space.CIPM infused more phenolic prepolymer into the Chinese fir.Not only producing more physical filling but also forming more hydrogen bond associations and chemical bond combinations.Compared with PIPM and unmodi-fied Chinese fir,the CIPM impregnated Chinese fir had better mechanical strength and water resistance.The cellulose chains in CIPM impregnated Chinese fir were more closely linked and their crystallinity were clearly improved.Changes in internal morphology and crystal structure explained the reason why the mechanical properties and water resistance of CIPM impregnated Chinese fir were improved significantly.This Chinese fir had lower thermal decomposition rates,higher decomposition residual rates,and smaller combustion flames,which confirmed that it possessed improved heat and fire resistance.展开更多
基金Supported by the National Natural Science Foundation of China(51765016,51475165,11462004)the Jiangxi Provincial Foundation for Leaders of Academic and Disciplines in Science(20162BCB22019)5511 Science and Technology Innovation Talent Project of Jiangxi Province(20165BCB18011)
文摘A compact annular-radial-orifice flow magnetorheological(MR)valve was developed to investigate the effects of radial resistance gap on pressure drop.The fluid flow paths of this proposed MR valve consist of a single annular flow channel,a single radial flow channel and an orifice flow channel through structure design.The finite element modelling and simulation analysis of the MR valve was carried out using ANSYS/Emag software to investigate the changes of the magnetic flux density and yield stress along the fluid flow paths under the four different radial resistance gaps.Moreover,the experimental tests were also conducted to evaluate the pressure drop,showing that the proposed MR valve has significantly improved its pressure drop at 0.5 mm width of the radial resistance gap when the annular resistance gap is fixed at 1 mm.
文摘The static dent resistance performance of the aluminum alloy double-curved panel formed using viscous pressure forming (VPF)was studied by finite element analysis,which mainly considers the forming process conditions.The whole simulation consisting of three stages,i.e.,forming,spring-back and static dent resistance,was carried out continuously using the finite element code ANSYS.The influence of blank holder pressure(BHP)and the drawbead on the stiffness and the static dent resistance of the panels formed using VPF was analyzed.The results show that the adequate setting of the drawbead can increase the plastic deformation of the double-curved panel,which is beneficial to the initial stiffness and the static dent resistance.There is an optimum BHP range for the stiffness and the static dent resistance.
基金Project(50575202) supported by the National Natural Science Foundation of China
文摘The structure and working principle of a self-deigned high pressure electronic pneumatic pressure reducing valve (EPPRV) with slide pilot are introduced.The resistance value formulas and the relationship between the resistance and pressure of three typical pneumatic resistances are obtained.Then,the method of static characteristics analysis only considering pneumatic resistances is proposed,the resistance network from gas supply to load is built up,and the mathematical model is derived from the flow rate formulas and flow conservation equations,with the compressibility of high pressure gas and temperature drop during the expansion considered in the model.Finally,the pilot spool displacement of 1.5 mm at an output pressure of 15MPa and the enlarging operating stroke of the pilot spool are taken as optimization targets,and the optimization is carried out based on genetic algorithm and the model mentioned above.The results show that the static characteristics of the EPPRV are significantly improved.The idea of static characteristics analysis and optimization based on pneumatic resistance network is valuable for the design of pneumatic components or system.
基金sponsored by the National Natural Science Foundation of China ( 51571150,11572222)Tianjin Natural Science Foundation ( 14JCYBJC16900)
文摘Recently,magnesium and its alloys have attracted more and more attention as promising implant materials due to their excellent properties such as good biocompatibility,biodegradation,non-toxicity and comparable mechanical properties with natural bone.They can be gradually degraded and absorbed so as to avoid the second surgery for implants removal after the tissues are healed completely.In addition,they are also able to prevent the stress shielding effect in human body environment because of the density,elastic modulus and yield strength of magnesium closer to the bone.Unfortunately,the high corrosion rate which causes early mechanical failure of the implants in physiological environment limits the widespread use of magnesium alloys for clinical application in biology.And the high corrosion process usually causes huge hydrogen evolution and alkalinization,resulting in problems against the implants as well as the surrounding tissues.In order to enhance the corrosion resistance of magnesium alloys,in this study,the ZEK100 magnesium alloy was pre-deformed with a highpressure torsion(HPT)process and then fabricated hydroxyapatite(HA)coatings with different contents of Mg(OH)2 nanopowder via hydrothermal method.The specimens were characterized by scanning electron microscope(SEM)and X-ray diffraction(XRD).At the same time,prior and after the HPT procedure,the metallography,microhardness and tensile tests of specimens were characterized.Meanwhile,the corrosion behavior of the specimens was evaluated by electrochemical impedance spectroscopy(EIS)and hydrogen evolution tests.And the interface bonding strength of the HA coating on the magnesium alloy substrate was evaluated by a tape adhesion test/scratch test.Results showed that HPT processing refined the grain size and introduced a great number of twins,resulting in the enhancement of microhardness and Young’s modulus of ZEK100 magnesium alloy,but hardness values at the edge were higher than those at the center due to the uneven shear strain.At the same conditions,the HA coating on HPT-ZEK was denser,thicker than that on ZEK sample and the crystal sizes of HA were smaller on HPT-ZEK.These were attributed to fine,uniform distributed secondary phases and lots of fine grains,twins,grain boundaries in HPT-ZEK substrates which can provide more nucleation sites for the HA crystal.In terms of the amount of Mg(OH)2 nanopowder,Mg(OH)2 nanopowder significantly influenced the microstructure and thickness of the HA coating.And at a 0.3 mg/mL content of Mg(OH)2 nanopowder,there was the densest,thickest HA coating on magnesium alloys,and the crystal size of HA was minimum.Specifically,the HA coating thickness on ZEK-03(0.3 mg/mL Mg(OH)2 nanopowder)was 1.8 times of that on ZEK-00(0 mg/mL Mg(OH)2 nanopowder),while the HA coating thickness on HPT-03 was 2.6 times of that on ZEK-00.And the adhesion strength of HA coating on HPT-03 substrate was better than that on ZEK-03.In addition,HPT technology and surface modification by HA coating simultaneously increased the corrosion resistance of ZEK100 magnesium alloy and the corrosion of HPT-ZEK samples occurred in a more uniform manner,while it was pitting on the surface of ZEK100 magnesium alloy.Therefore,there was the best corrosion resistance on HPT-03 sample,which could promote the application of magnesium alloys in biomedical fields.
基金supported by grants from the National Natural Sciences Foundation of China (No.30600294)Shanghai Scientific and Technological Innovation Plan(No.08411951300)
文摘The association between fasting plasma ghrelin levels and insulin resistance and blood pressure(BP) in octogenarians was investigated in this study.A total of 487 unrelated octogenarians(including 203 men and 284 women) were enrolled in this cross-sectional study at the Healthy Care Center of Shanghai East Hospital,Tongji University,China,from October 2008 to April 2009.Plasma ghrelin was determined by using the enzyme linked immunosorbent assay(ELISA).Insulin sensitivity was assessed using the homeostasis model of assessment-insulin resistance(HOMA-IR).The age of the participants ranged from 80 to 89 years(mean=83.9±4.8 years) with a body mass index(BMI) of 25.3±4.9 kg/m2.Plasma ghrelin level[w1]s were 20.94±5.34 μg/L,being 20.89±5.53 μg/L in men and 21.38±3.73 μg/L in women respectively.Plasma ghrelin was not associated with systolic(P=0.981) or diastolic(P=0.724) BP,waist circumference(P=0.278),fasting insulin(P=0.246),fasting blood glucose(FBG)(P=0.693) and HOMA-IR(P=0.232).In the control cohort,no significant differences in plasma ghrelin were found between genders(P=0.489),and among subjects with hypertension(BP>140/90 mmHg)(P=0.284) and type 2 diabetes(P=0.776).In conclusion,fasting plasma ghrelin levels are not directly correlated with insulin resistance and BP among octogenarians.
基金supported by the National Basic Research Program of China (Grant No. 2011CB808204)the National Natural Science Foundation of China (Grant Nos. 11074094 and 91014004)the Fundamental Research Funds for Jilin University, China (Grant No. 450060491500)
文摘The in situ electrical resistance and transport activation energies of solid C60 fullerene have been measured under high pressure up to 25 GPa in the temperature range of 300-423 K by using a designed diamond anvil cell. In the experiment, four parts of boron-doped diamond films fabricated on one anvil were used as electrical measurement probes and a W-Ta thin film thermocouple which was integrated on the other diamond anvil was used to measure the temperature. The current results indicate that the measured high-pressure resistances are bigger than those reported before at the same pressure and there is no pressure-independent resistance increase before 8 GPa. From the temperature dependence of the resistivity, the C60 behaviors as a semiconductor and the activation energies of the cubic C60 fullerene are 0,49, 0.43, and 0.36 eV at 13, 15, and 19 GPa, respectively.
基金supported by the Foundation for the National Key R&D Program(2022YFD1800400)Innovative Research Groups of the National Natural Science Foundation of China(32121004)Natural Science Foundation of Guangdong Province of China(2021A1515011159)。
文摘Monitoring the prevalence of antimicrobial resistance genes(ARGs)is vital for addressing the global crisis of antibiotic-resistant bacterial infections.Despite its importance,the characterization of ARGs and microbiome structures,as well as the identification of indicators for routine ARG monitoring in pig farms,are still lacking,particularly concerning variations in antimicrobial exposure in different countries or regions.Here,metagenomics and random forest machine learning were used to elucidate the ARG profiles,microbiome structures,and ARG contamination indicators in pig manure under different antimicrobial pressures between China and Europe.Results showed that Chinese pigs exposed to high-level antimicrobials exhibited higher total and plasmid-mediated ARG abundances compared to those in European pigs(P<0.05).ANT(6)-Ib,APH(3')-IIIa,and tet(40)were identified as shared core ARGs between the two pig populations.Furthermore,the core ARGs identified in pig populations were correlated with those found in human populations within the same geographical regions.Lactobacillus and Prevotella were identified as the dominant genera in the core microbiomes of Chinese and European pigs,respectively.Forty ARG markers and 43 biomarkers were able to differentiate between the Chinese and European pig manure samples with accuracies of 100%and 98.7%,respectively.Indicators for assessing ARG contamination in Chinese and European pigs also achieved high accuracy(r=0.72-0.88).Escherichia flexneri in both Chinese and European pig populations carried between 21 and 37 ARGs.The results of this study emphasize the importance of global collaboration in reducing antimicrobial resistance risk and provide validated indicators for evaluating the risk of ARG contamination in pig farms.
文摘Objectives To investigate clinical characteristics, target organ damage, and the associated risk factors of the patients aged ≥ 80 yearswith true resistant hypertension (RH). Methods Patients aged ≥ 80 years with hypertension (n = 1163) were included in this study. Theincluded participants attended a structured clinical examination and an evaluation of RH was carried out. The prevalence, clinical characteristicsand target organ damage of patients with RH were assessed. The associated clinical risk factors were analyzed by using logistic regression.Results The prevalence of RH diagnosis by 24-h ambulatory blood pressure monitoring assessment was 21.15%. End-diastolic left ven-tricular internal dimension, left ventricular mass index as well as prevalence of left ventricular hypertrophy were significantly greater in pa-tients with RH than in control group. The common carotid artery intimal media thickness, carotid walls thickness, common carotid arterydiameter and relative wall thickness were significant greater in RH group than in control. A relatively higher level of creatinine, estimatedglomerular filtration rate, microalbuminuria and retinal changes was found in RIt group than in control. A multivariate analysis showed thatpatients with a history of diabetes, higher body mass index (BMI) and lipid profiles were independent risk factors of RH. Conclusions Theprevalence of RH in patients aged ≥ 80 years was within the range of reported rates of the general population. Subjects with RH diagnosisshowed a higher occurrence of target organ damage than patients with well controlled blood pressure. Patients with diabetes, higher BMI andserum lipid profiles were independent risk factors for RH in patients aged ≥ 80 years.
文摘The FW process is a prefect method of manufacturing FRP composite air vessel resisting high pressure and aerial press vessel.In this paper FW pattern of FRP composite air vessel resisting high pressure was analyzed in a nutshell.The stability of FW patterns on end head is very sensitive to changing of pattern parameter.Consequently,its FW pattern was based on geodesic track.The FW angles and on equators depend on the dimension of end part and the condition of geodesic FW.Generally speaking, the polar holes of rocket engine shell are disproportional.Therefore,the FW angles of the shell column are changeable.The feasi- bility of nongeodesic FW of the shell column was discussed in this paper.Furthermore,it expounded the indispensable condition be- tween the length of shell column and the FW friction coefficient.At the same time,the general mathematic models of the movement control of nongeodesic FW were deduced.
基金Project supported by the Science Fonds from the Ministry of Science and Technology of China(Grant Nos.2017YFA0302903,017YFA0303103,2016YFA0300502,and 2015CB921302)the National Natural Science Foundation of China(Grant Nos.11674406 and 11674372)+1 种基金the“Strategic Priority Research Program(B)”of the Chinese Academy of Sciences(Grant Nos.XDB07020300 and XDB07020200)the Youth Innovation Promotion Association of the Chinese Academy of Sciences
文摘Nematic order and its fluctuations have been widely found in iron-based superconductors. Above the nematic order transition temperature, the resistivity shows a linear relationship with the uniaxial pressure or strain along the nematic direction and the normalized slope is thought to be associated with nematic susceptibility. Here we systematically studied the uniaxial pressure dependence of the resistivity in Sr1 _xBaxFel.97Nio.03As2, where nonlinear behaviors are observed near the nematic transition temperature. We show that it can be well explained by the Landau theory for the second-order phase transitions considering that the external field is not zero. The effect of the coupling between the isotropic and nematic channels is shown to be negligible. Moreover, our results suggest that the nature of the magnetic and nematic transitions in Srl xBaxFe2As2 is determined by the strength of the magnetic-elastic coupling.
基金supported by National Hi-tech Research and Development Program of China (863 Program, No. 2002AA401002-05).
文摘Sampling study is an effective exploration method, but the most extreme environments of hydrothermal vents pose considerable engineering challenges for sampling hydrothermal fluids. Moreover, traditional sampler systems with sample valves have difficulty in maintaining samples in situ pressure. However, decompression changes have effect on microorganisms sensitive to such stresses. To address the technical difficulty of collecting samples from hydrothermal vents, a new bidirectional high pressure-resistant sample valve with balanced poppet was designed. The sample valve utilizes a soft high performance plastic "PEEK" as poppet. The poppet with inapposite dimension is prone to occur to plastic deformation or rupture for high working pressure in experiments. To address this issue, based on the fmite element model, simulated results on stress distribution of the poppet with different structure parameters and preload spring force were obtained. The static axial deformations on top of the poppet were experimented. The simulated results agree with the experimental results. The new sample valve seals well and it can withstand high working pressure.
基金Fundamental Research Fund for the Central Universities,China(Nos.2232020G-01 and 19D110106)Young Elite Scientists Sponsorship Program by China Association for Science and Technology,China(No.2017QNRC001)Graduate Student Innovation Fund of Donghua University,China(No.20D310111)。
文摘Flexible piezoresistive pressure sensors can offer convenient detection of mechanical deformations for wearable electronics.Previous studies of flexible piezoresistive pressure sensors focus on the sensitivity but the low-cost and self-powered sensors remain a challenge due to the deviation of resistance signal acquisition caused by thermoelectric voltage.Here,piezoresistive pressure sensors with ultralow Seebeck coefficient of-0.72μV/K based on carbon nanotubes(CNTs)/polyethyleneimine(PEI)/melamine(CPM)sponge are reported.Due to the diminished Seebeck effect,the CPM sponge pressure sensors successfully reduce the deviation to 18.75%and can keep stable sensitivity and resistance change under a very low working voltage and change temperature environment.The stable properties of the sensors make them successful to work for real-time sensing in self-powered wearable electronics.
基金supported by the Spark Program of the second Affiliated Hospital of Anhui Medical University (Grant No.2015hhjh04)National Natural Science Foundation of China under Grant No.51777206+6 种基金Natural Science Foundation of Anhui Province (Grant No.1708085MA13 and No.1708085MB47)Science Foundation of Institute of Plasma Physics,Chinese Academy of Sciences under Grant (No.DSJJ-14-YY02)City University of Hong Kong Applied Research Grant (ARG) (No.9667144)Hong Kong Research Grants Council (RGC) General Research Funds (GRF) (No.City U 11301215)Doctoral Fund of Ministry of Education of China (No.2017M612058)Specialized Research Fund for the Doctoral Program of Hefei University of Technology (No.JZ2016HGBZ0768)Foundation of Anhui Province Key Laboratory of Medical Physics and Technology (Grant No.LMPT2017Y7BP0U1581)
文摘In this research,an atmospheric-pressure air plasma is used to inactivate the multidrug-resistant Acinetobacter baumannii in liquid.The efficacy of the air plasma on bacterial deactivation and the cytobiological variations after the plasma treatment are investigated.According to colony forming units,nearly all the bacteria(6-log) are inactivated after 10 min of air plasma treatment.However,7% of the bacteria enter a viable but non-culturable state detected by the resazurin based assay during the same period of plasma exposure.Meanwhile,86% of the bacteria lose their membrane integrity in the light of SYTO 9/PI staining assay.The morphological changes in the cells are examined by scanning electron microscopy and bacteria with morphological changes are rare after plasma exposure in the liquid.The concentrations of the long-living RS,such as H2O2,NO3^- and O3,in liquid induced by plasma treatment are measured,and they increase with plasma treatment time.The changes of the intracellular ROS may be related to cell death,which may be attributed to oxidative stress and other damage effects induced by RS plasma generated in liquid.The rapid and effective bacteria inactivation may stem from the RS in the liquid generated by plasma and air plasmas may become a valuable therapy in the treatment of infected wounds.
基金supported by the Chinese Major National Scientific and Technological Program (2011ZX05001)Chinese Postdoctoral Fund (2013M540114)
文摘In exploration for tight oil, the content and saturation of hydrocarbon in the tight reservoir is a key factor for evaluating the reserve. Therefore, it is necessary to study the geological history of hydrocarbon accumulation and the tight oil charging process. However, kinetic models used for petroleum development are not applicable for petroleum exploration. In this study, a static resistance model[ is proposed after analyzing resistances in ultra-slow flow in porous media. Using this model, the disco^atinuous pattern of oil charging is reproduced through incompressible Navier-Stokes equations, the phase field method and the finite element method. This study also explains macroscopic percolation behavior with microscopic flow mechanisms and discusses some issues in ultra-slow flow in a micro/nano pore-throat network. The resistance analysis reveals that capillary resistance and dissipation resistance are dominant factors in the mechanism of oil accumulation in tight reservoirs. Numerical simulations show that pressure thresholds exist and result in discontinuous oil charging. Generally, it is proven that the static model is more applicable than kinetic models in describing oil accumulation in tight reservoirs.
基金This work was financially supported by the National Natural Science Foundation of China (No. 50532090).
文摘PolycrystaUine SnO2 thin films were deposited on sapphire substrates at 450℃ under different ambient oxygen pressures by pulsed laser deposition technique. The effect of ambient oxygen pressure on the structural, optical and electrical properties of SnO2 thin films was studied. X-my diffraction and Hall measurements show that increasing the ambient oxygen pressure can improve crystallization of the films and decrease resistivity of the films. A violet emission peak centered at 409 nm was observed from photoluminescence measurements for SnO2 films under deposition ambient oxygen pressure above 5 Pa, which is related to the improvement of crystalline of the films.
基金This work was financially supported by the National Natural Science Foundation of China (No.50574004).
文摘The desensitization degree of emulsion explosives (EE) was calculated with the peak pressure of explosion shock waves tested in water. To an explosive, the less the desensitization degree, the better the compression resistance, so the compression resistance of an explosive can be compared and analyzed quantificationally with the desensitization degree. The influence of an emulsifier on the pressure desensitization of EE was studied, including the content and category of emulsifiers. Three kinds of emulsifiers (Span-80, compound emulsifier, and T-152) were used in the tests. The experimental results show that both the content and category of emulsifiers make a great effect on the pressure desensitization of EE. The desensitization degree of EE reduces with the emulsifier content being increased, but there is an optimal content of an emulsifier for the compression resistance of EE. While the content of Span-80 reaches 4wt%, the desensitization degree of EE becomes a minimal value, and augments somewhat if the emulsifier content is increased more. That is to say, the compression resistance of EE becomes the highest while the content of Span-80 is 4wt%, and the compression resistance will decline if the content of Span-80 is increased more. The compression resistance of the explosive emulsified by compound emulsifier is the highest among all the explosives, when the content of the whole components and manufacturing engineering are kept invariable.
基金Project(2011-0009022) supported by Basic Science Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education,Science and Technology of Korea
文摘The pressure characteristics inside single loop oscillating heat pipe (OHP) having 4.5 mm inner diameter copper tube with the loop height of 440 mm were addressed. Distilled water was used as working fluid inside the OHP with different filling ratios of 40%, 60% and 80% of total inside volume. Experimental results show that the thermal characteristics are significantly inter-related with pressure fluctuations as well as pressure frequency. And the pressure frequency also depends upon the evaporator temperature that is maintained in the range of 60-96 ℃. Piezoresistive absolute pressure sensor (Model-Kistler 4045A5) was used to take data. The investigation shows that the filling ratio of 60% gives the highest inside pressure magnitude at maximum number of pressure frequency at any of set evaporator temperature and the lowest heat flow resistance is achieved at 60% filling ratio.
文摘AIM: To define the corneal hysteresis(CH), corneal resistance factor(CRF), Goldmann-correlated intraocular pressure(IOPg) and corneal compensated intraocular pressure(IOPcc) prior to and following coaxial micro-incision phacoemulsification in patients with corneal astigmatism. METHODS: Of 97 patients with cataracts were enrolled in the study. Group 1 included patients with corneal astigmatism(K1-K2) values of K1-K2<+1.0 D, and group 2 with values of K1-K2 ≥+1.0 D and ≤+2.25 D. Coaxial micro-incision phacoemulsification of a corneal incision of 2.0 mm with intraocular lens(IOL) implantation was performed. CH, CRF, IOPg, IOPcc, waveform score(WS) were measured preoperatively and one week, one month postoperatively using an Ocular Response Analyzer. Axial length(AXL) was calculated by Tomey Optical Biometer OA 2000.RESULTS: Group 1 consisted of 51 patients with mean corneal astigmatism value of +0.49±0.25 D. Group 2 included 46 patients with astigmatism of +1.43±0.43 D. In group 1, CRF(t=2.68, P<0.05), CH(t=2.64, P<0.05) and WS(t=3.51, P<0.05) were significantly lower one week postoperatively, when compared to the preoperative values. CRF significantly decreased(t=3.61, P<0.05) when measured one month following the surgery. In group 2 CH(t=5.92, P<0.05), and WS(t=3.96, P<0.05) were significantly lowered one week after cataract surgery. Moreover, we observed a significant decrease in IOPg(t=2.24, P<0.05), CRF(t=5.05, P<0.05) and CH(t=2.31, P<0.05) one month after phacoemulsification. There was no statistically significant(t=-0.83, P=0.41) difference in AXL between study groups.CONCLUSION: CRF, CH and IOPg are reduced in patients with preoperative corneal astigmatism equal or higher than +1.0 D and lower than +2.25 D. Hence, bias of IOPg measurement in these patients may cause underestimation of the real IOP both before and after cataract surgery. The measurement of IOPcc allows the precise assessment of IOP pre-and postoperatively, independently on corneal astigmatism, CH and CRF values.
基金This work was financially supported by Hunan Provincial Technical Innovation Platform and Talent Program in Science and Technology,China(2019RS2040)the National Natural Science Foundation of China(31770606)Major Science and Technology Program of Hunan Province,PR China(2017NK1010).
文摘The Chinese fir wood was impregnated using a cyclic increasingpressure method(CIPM)with phenolic prepolymers as the impregnating modifier.Unmodified Chinese fir and progressive increasing-pressure method(PIPM)impregnated Chinese fir were used as reference samples and were compared and analyzed.The product’s chemical structure,internal morphology,crystal structure,and heat resistance were characterized.The transversal and longitudinal sections showed better filling effects,so that it bore greater external loading and reduced the water storage space.CIPM infused more phenolic prepolymer into the Chinese fir.Not only producing more physical filling but also forming more hydrogen bond associations and chemical bond combinations.Compared with PIPM and unmodi-fied Chinese fir,the CIPM impregnated Chinese fir had better mechanical strength and water resistance.The cellulose chains in CIPM impregnated Chinese fir were more closely linked and their crystallinity were clearly improved.Changes in internal morphology and crystal structure explained the reason why the mechanical properties and water resistance of CIPM impregnated Chinese fir were improved significantly.This Chinese fir had lower thermal decomposition rates,higher decomposition residual rates,and smaller combustion flames,which confirmed that it possessed improved heat and fire resistance.