In-situ pressure-preserved coring(IPP-Coring)is considered to be the most reliable and efficient method for the identification of the scale of oil and gas resources.During IPP-Coring,because the rotation behavior of t...In-situ pressure-preserved coring(IPP-Coring)is considered to be the most reliable and efficient method for the identification of the scale of oil and gas resources.During IPP-Coring,because the rotation behavior of the pressure controller valve cover in different medium environments is unclear,interference between the valve cover and inner pipe may occur and negatively affect the IPP-Coring success rate.To address this issue,we conducted a series of indoor experiments employing a high-speed camera to gain greater insights into the valve cover rotation behavior in different medium environments,e.g.,air,water,and simulated drilling fluids.The results indicated that the variation in the valve cover rotation angle in the air and fluid environments can be described by a one-phase exponential decay function with a constant time parameter and by biphasic dose response function,respectively.The rotation behavior in the fluid environments exhibited distinct elastic and gravitational acceleration zones.In the fluid environments,the density clearly impacted the valve cover closing time and rotation behavior,whereas the effect of viscosity was very slight.This can be attributed to the negligible influence of the fluid viscosity on the drag coefficient found in this study;meanwhile,the density can increase the buoyancy and the time period during which the valve cover experienced a high drag coefficient.Considering these results,control schemes for the valve cover rotation behavior during IPP-Coring were proposed for different layers and geological conditions in which the different drilling fluids should be used,e.g.,the use of a high-density valve cover in high-pore pressure layers.展开更多
Objective Current clinical evidence on the effects of home blood pressure telemonitoring(HBPT)on improving blood pressure control comes entirely from developed countries.Thus,we performed this randomized controlled tr...Objective Current clinical evidence on the effects of home blood pressure telemonitoring(HBPT)on improving blood pressure control comes entirely from developed countries.Thus,we performed this randomized controlled trial to evaluate whether HBPT plus support(patient education and clinician remote hypertension management)improves blood pressure control more than usual care(UC)in the Chinese population.Methods This single-center,randomized controlled study was conducted in Beijing,China.Patients aged 30-75 years were eligible for enrolment if they had blood pressure[systolic(SBP)≥140 mmHg and/or diastolic(DBP)≥90 mmHg;or SBP≥130 mmHg and/or DBP≥80 mmHg with diabetes].We recruited 190 patients randomized to either the HBPT or the UC groups for 12 weeks.The primary endpoints were blood pressure reduction and the proportion of patients achieving the target blood pressure.Results Totally,172 patients completed the study,the HBPT plus support group(n=84),and the UC group(n=88).Patients in the plus support group showed a greater reduction in mean ambulatory blood pressure than those in the UC group.The plus support group had a significantly higher proportion of patients who achieved the target blood pressure and maintained a dipper blood pressure pattern at the12th week of follow-up.Additionally,the patients in the plus support group showed lower blood pressure variability and higher drug adherence than those in the UC group.Conclusion HBPT plus additional support results in greater blood pressure reduction,better blood pressure control,a higher proportion of dipper blood pressure patterns,lower blood pressure variability,and higher drug adherence than UC.The development of telemedicine may be the cornerstone of hypertension management in primary care.展开更多
Deep oil exploration coring technology cannot accurately maintain the in-situ pressure and temperature of samples, which leads to a distortion of deep oil and gas resource reserve evaluations based on conventional cor...Deep oil exploration coring technology cannot accurately maintain the in-situ pressure and temperature of samples, which leads to a distortion of deep oil and gas resource reserve evaluations based on conventional cores and cannot guide the development of deep oil and gas resources on Earth. The fundamental reason is the lack of temperature and pressure control in in-situ coring environments. In this paper, a pressure control method of a coring device is studied. The theory and method of deep intelligent temperature-pressure coupling control are innovatively proposed, and a multifield coupling dynamic sealing model is established. The optimal cardinality three term PID (Proportional-Integral-Differential) intelligent control algorithm of pressure system is developed. The temperature-pressure characteristic of the gas-liquid two-phase cavity is analyzed, and the pressure intelligent control is carried out based on three term PID control algorithms. An in-situ condition-preserved coring (ICP-Coring) device is developed, and an intelligent control system for the temperature and pressure of the coring device is designed and verified by experiments. The results show that the temperature-pressure coupling control system can effectively realize stable sealing under temperature-pressure fields of 140 MPa and 150 °C. The temperature-pressure coupling control method can accurately realize a constant pressure inside the coring device. The maximum working pressure is 140 MPa, and the effective pressure compensation range is 20 MPa. The numerical simulation experiment of pressure system control algorithm is carried out, and the optimal cardinality and three term coefficients are obtained. The pressure steady-state error is less than 0.01%. The method of temperature-pressure coupling control has guiding significance for coring device research, and is also the basis for temperature-pressure decoupling control in ICP-Coring.展开更多
Introduction: The management of hypertension is mostly based on pharmacotherapy and hygienic and dietary measures (HDMs) for which little data is available in Cameroon. The concern to improve the quality of life of hy...Introduction: The management of hypertension is mostly based on pharmacotherapy and hygienic and dietary measures (HDMs) for which little data is available in Cameroon. The concern to improve the quality of life of hypertensive patients led us to study the knowledge, compliance and effect of HDMs among Cameroonian hypertensive patients. Methods: This was a cross-sectional study carried out at the Douala General Hospital;the census of patients was carried out from 05 March to 10 May 2018. The data evaluated were knowledge and compliance with HDMs with an inference of their effect on blood pressure control. Results: We recruited 330 participants at mean age of 60 ± 11 years, 37.9% men;57.3% with blood pressure (BP) controlled. Out of 330 subjects, 308 (93.3%) who had been educated about dietary health measures for hypertension were assessed on knowledge, compliance and effect of these measures against 22 (6.7%) who had never heard about them. Around 85.7% of participants had good knowledge of HDMs and 78.9% had good compliance with them. There was no statistically significant influence of knowledge and compliance with HDMs on blood pressure control. Conclusion: The level of knowledge and adherence to HDMs of hypertensive patients at the Douala General Hospital was appreciable. It is however appropriate for physicians to intensify patient education on HDMs and BP control.展开更多
Objective:To explore the risk factors of diabetic nephropathy and its correlation with blood pressure control.Methods:A retrospective analysis of 80 patients with diabetic nephropathy(diabetic nephropathy group)and an...Objective:To explore the risk factors of diabetic nephropathy and its correlation with blood pressure control.Methods:A retrospective analysis of 80 patients with diabetic nephropathy(diabetic nephropathy group)and another 80 patients with diabetes(diabetic group)who were admitted to the Department of Nephrology and Endocrinology at our hospital from October 2021 to October 2022 was conducted.The general data of the two groups were compared,the influencing factors associated with the two groups were analyzed unilaterally,and unconditional dichotomous logistic regression was performed to analyze the influencing factors in patients with diabetic nephropathy.Results:There were no significant differences in high-density lipoprotein,systolic blood pressure,diastolic blood pressure,and creatinine between the two groups(P>0.05);however,compared with the diabetic group,the DN group had significantly elevated glycated hemoglobin,low-density lipoprotein,24-h urine protein,insulin resistance,and diabetes duration≥10 years(P<0.05).Conclusion:The clinical research on the correlation between the incidence of hypertension and the control of blood pressure in patients with diabetic nephropathy should be strengthened in order to formulate reasonable and feasible treatment plans.展开更多
This paper describes a supervisory hierarchical fuzzy controller (SHFC) for regulating pressure in a real-time pilot pressure control system. The input scaling factor tuning of a direct expert controller is made usi...This paper describes a supervisory hierarchical fuzzy controller (SHFC) for regulating pressure in a real-time pilot pressure control system. The input scaling factor tuning of a direct expert controller is made using the error and process input parameters in a closed loop system in order to obtain better controller performance for set-point change and load disturbances. This on-line tuning method reduces operator involvement and enhances the controller performance to a wide operating range. The hierarchical control scheme consists of an intelligent upper level supervisory fuzzy controller and a lower level direct fuzzy controller. The upper level controller provides a mechanism to the main goal of the system and the lower level controller delivers the solutions to a particular situation. The control algorithm for the proposed scheme has been developed and tested using an ARM7 microcontroller-based embedded target board for a nonlinear pressure process having dead time. To demonstrate the effectiveness, the results of the proposed hierarchical controller, fuzzy controller and conventional proportional-integral (PI) controller are analyzed. The results prove that the SHFC performance is better in terms of stability and robustness than the conventional control methods.展开更多
Water-assisted injection molding(WAIM),a newly developed fluid-assisted injection molding technology has drawn more and more attentions for the energy saving,short cooling circle time and high quality of products.Ex...Water-assisted injection molding(WAIM),a newly developed fluid-assisted injection molding technology has drawn more and more attentions for the energy saving,short cooling circle time and high quality of products.Existing research for the process of WAIM has shown that the pressure control of the injecting water is mostly important for the WAIM.However,the proportional pressure control for the WAIM system is quite complex due to the existence of nonlinearities in the water hydraulic system.In order to achieve better pressure control performance of the injecting water to meet the requirements of the WAIM,the proportional pressure control of the WAIM system is investigated both numerically and experimentally.A newly designed water hydraulic system for WAIM is first modeled in AMEsim environment,the load characteristics and the nonlinearities of water hydraulic system are both considered,then the main factors affecting the injecting pressure and load flow rate are extensively studied.Meanwhile,an open-loop model-based compensation control strategy is employed to regulate the water injection pressure and a feedback proportional integrator controller is further adopted to achieve better control performance.In order to verify the AMEsim simulation results WAIM experiment for particular Acrylonitrile Butadiene Styrene(ABS) parts is implemented and the measured experimental data including injecting pressure and flow rate results are compared with the simulation.The good coincidence between experiment and simulation shows that the AMEsim model is accurate,and the tracking performance of the load pressure indicates that the proposed control strategy is effective for the proportional pressure control of the nonlinear WAIM system.The proposed proportional pressure control strategy and the conclusions drawn from simulation and experiment contribute to the application of water hydraulic proportional control and WAIM technology.展开更多
The performance of the designed digital electro-pneumatic cabin pressure control system for the cabin pressure schedule of transport aircraft is investigated.For the purpose of this study,an experimental setup consist...The performance of the designed digital electro-pneumatic cabin pressure control system for the cabin pressure schedule of transport aircraft is investigated.For the purpose of this study,an experimental setup consisting of a simulated hermetic cabin and altitude simulation chamber is configured for cabin pressure control system operation.A series of experimental tests are executed to evaluate the performance of the cabin pressure control system.The parameters of the PID controller are optimized.In the optimization process,the variation regularity of the rate of cabin pressure change under various conditions is considered.An approach to prioritize the control of the rate of change of cabin pressure based on the flight status model is proposed and verified experimentally.The experimental results indicate that the proposed approach can be adopted for the designed digital electro-pneumatic cabin pressure control system to obtain a better cabin pressure schedule and rate of cabin pressure change.展开更多
Multi-level pressure source system is a novel hydraulic system with distinct advantage of energy saving. In order to balance each pressure level of the multi-level pressure source system, a pump motor energy transfer ...Multi-level pressure source system is a novel hydraulic system with distinct advantage of energy saving. In order to balance each pressure level of the multi-level pressure source system, a pump motor energy transfer unit is usually equipped. However, the pump motor energy transfer has the characteristics of poor starting and low response, which cause long time of pressure adjustment and large pressure jitter when the transformer is switched to system suddenly and the motor-side pressure has pressure impact when rail of the pump-side is switched. To address these problems, this paper proposes a compound control strategy of feedforward compensation control with Fuzzy-PID to improve the controllability of the multi-level pressure source system. A test rig of the pump motor energy transfer unit is built and the controllability of compound controller and PID controller are compared. The experiment results show that, compared with the traditional PID, the adjustment time and the pressure impact are reduced by 20% and 25% with the proposed compound control strategy. Therefore, the presented compound control strategy can be used to improve starting performance and robustness of the pump motor energy transfer unit control system.展开更多
In this paper the control mechanism of solenoid valve is analyzed,which shows the solenoid valve control is actually the control of coil current.The response characteristic of coil current is related to coil inductanc...In this paper the control mechanism of solenoid valve is analyzed,which shows the solenoid valve control is actually the control of coil current.The response characteristic of coil current is related to coil inductance and resistance.The coil resistance is influenced greatly by the ambient temperature and the self-heating of coil,which affects the control precision of coil current.First,considering the heat dissipation mode of coil,the coil temperature model is established from the perspective of heat conduction,and a temperature compensation algorithm for hydraulic system pressure control is put forward.Then the hardware-in-the-loop testbed is set up by using the dSPACE platform,carrying out wheel cylinder pressurization tests with inlet valve fully opened at-40℃ and 20℃,and testing the actual pressure of wheel cylinder with the target pressures at-40℃ and 6 000 kPa/s(pressurization rate).The results show that the pressure control temperature compensation algorithm proposed in this paper accurately corrects the influence of resistance temperature drift on the response accuracy of wheel cylinder pressure.After the correction,the pressure difference is less than 500 kPa,which can meet the control accuracy requirements of solenoid valve,enriching the linear control characteristic of solenoid valve.展开更多
A pressurizer is one of important equipment in a pressurized water reactor plant. It is used to maintain the pressure of primary coolant within allowed range because the sharp change of coolant pressure affects the se...A pressurizer is one of important equipment in a pressurized water reactor plant. It is used to maintain the pressure of primary coolant within allowed range because the sharp change of coolant pressure affects the security of reactor, therefor, the study of pressurizer’s pressure control methods is very important. In this paper, an adaptive fuzzy controller is presented for pressure control of a presurizer in a nuclear power plant. The controller can on-line tune fuzzy control rules and parameters by self-learning in the actual control process, which possesses the way of thinking like human to make a decision. The simulation results for a pressurized water reactor plant show that the adaptive fuzzy controller has optimum and intelligent characteristics, which prove the controller is effective.展开更多
It is very important to maintain the level of mean arterial pressure (MAP). The MAP control is applied in many clinical situations, including limiting bleeding during cardiac surgery and promoting healing for patien...It is very important to maintain the level of mean arterial pressure (MAP). The MAP control is applied in many clinical situations, including limiting bleeding during cardiac surgery and promoting healing for patient' s post-surgery. This paper presents a fuzzy controller-based multiple-model adaptive control system for postoperative blood pressure management. Multiple-model adaptive control (MMAC) algorithm is used to identify the patient model, and it is a feasible system identification method even in the presence of large noise. Fuzzy control (FC) method is used to design controller bank. Each fuzzy controller in the controller bank is in fact a nonlinear proportional-integral (PI) controller,whose proportional gain and integral gain are adjusted continuously according to error and rate of change of error of the plant output, resulting in better dynamic and stable control performance than the regular PI controller, especially when a nonlinear process is involved. For demonstration, a nonlinear, pulsatile-flow patient model is used for simulation, and the results show that the adaptive control system can effectively handle the changes in patient's dynamics and provide satisfactory performance in regulation of blood pressure of hypertension patients.展开更多
Acute stress concentration plays an important role in plaque rupture and may cause stroke or myocardial infarction.Quantitative evaluation of the relation between in vivo plaque stress and variations in blood pressure...Acute stress concentration plays an important role in plaque rupture and may cause stroke or myocardial infarction.Quantitative evaluation of the relation between in vivo plaque stress and variations in blood pressure and flow rates is valuable to optimize daily monitoring of the cardiovascular system for high-risk patients as well as to set a safe physical exercise intensity for better quality of life.In this study,we constructed an in vivo stress model for a human carotid bifurcation with atherosclerotic plaque,and analyzed the effects of blood pressure,flow rates,plaque stiffness,and stenosis on the elastic stress and fluid viscous stress around the plaque.According to the maximum values of the mechanical stress,we define a risk index to predict the risk level of plaque rupture under different exercise intensities.For a carotid bifurcation where the blood flow divides,the results suggest that the stenosis ratio determines the ratio of the contributions of elastic shear stress and viscous shear stress to plaque rupture.A n increase of the plaque stiffness enhances the maximum elastic shear stress in the plaque,indicating that a high-stiffness plaque is more prone to rupture for given stenosis ratio.High stress co-localization at the shoulder of plaques agrees with the region of plaque injury in clinical observations.It is demonstrated that,due to the stress-shield effect,the rupture risk of a high-stiffness plaque tends to decrease under high-stenosis conditions,suggesting the existence of a specific stenosis corresponding to the maximum risk.This study may help to complement risk stratification of vulnerable plaques in clinical practice and provides a stenosis mechanical property-specific guide for blood pressure control in cardiovascular health management.展开更多
A nonlinear pressure controller was presented to track desired feeding pressure for the cutter feeding system(CFS) of trench cutter(TC) in the presence of unknown external disturbances.The feeding pressure control of ...A nonlinear pressure controller was presented to track desired feeding pressure for the cutter feeding system(CFS) of trench cutter(TC) in the presence of unknown external disturbances.The feeding pressure control of CFS is subjected to unknown load characteristics of rock or soil; in addition,the geological condition is time-varying.Due to the complex load characteristics of rock or soil,the feeding velocity of TC is related to geological conditions.What is worse,its dynamic model is subjected to uncertainties and its function is unknown.To deal with the particular characteristics of CFS,a novel adaptive fuzzy integral sliding mode control(AFISMC) was designed for feeding pressure control of CFS,which combines the robust characteristics of an integral sliding mode controller and the adaptive adjusting characteristics of an adaptive fuzzy controller.The AFISMC feeding pressure controller is synthesized using the backstepping technique.The stability of the overall closed-loop system consisting of the adaptive fuzzy inference system,integral sliding mode controller and the cutter feeding system is proved using Lyapunov theory.Experiments are conducted on a TC test bench with the AFISMC under different operating conditions.The experimental results demonstrate that the proposed AFISMC feeding pressure controller for CFS gives a superior and robust pressure tracking performance with maximum pressure tracking error within ?0.3 MPa.展开更多
This paper presents a technique for controlling the pressure of a molten metal when using a new type of iron casting method called sand mold press casting to realize high productivity and obtain high-quality products....This paper presents a technique for controlling the pressure of a molten metal when using a new type of iron casting method called sand mold press casting to realize high productivity and obtain high-quality products.The past test results using this method showed a casting yield of 90% to 95%,while conventional methods only show a casting yield of 60% to 70%.Although the press casting method does not require a sprue cup or runner channel casting defects such as metal penetration are often caused by the high pressure in the high-velocity pressing part of this casting process.Therefore,we proposed a pressure control method with a mathematical model of molten metal pressure,and with it we achieved experimental confirmation of the successful production of brake drums at different pressing temperatures.Results show that the proposed pressing control method can realize sound,penetration-free casting production.However,the theoretical analysis and design of this pressing process had not previously been studied sufficiently,and therefore this paper presents the theoretical design algorithm for the process as well as its experimental confirmation.展开更多
Control design is important for PEMFC (proton exchange membrane fuel cell) distributed power generator to satisfy user requirement for safe and stable operation. For a complex multi-variable dynamic system, a dynami...Control design is important for PEMFC (proton exchange membrane fuel cell) distributed power generator to satisfy user requirement for safe and stable operation. For a complex multi-variable dynamic system, a dynamic simulation model is first established. In view of close coupling and non-linear relationships between variables, the intelligent auto-adapted PI decoupling control method is used. From the simulation results it is found that, by bringing quadratic performance index in the single neuron, constructing adaptive PI controller, and adjusting gas flow rates through the second pressure relief valve and air compressor coordinately, both anode and cathode pressures can be maintained at ideal levels.展开更多
Distillation column control is widely explored in literature due to its complexity and importance in chemical and petrochemical industries. In this process, pressure represents one of the most important variables to b...Distillation column control is widely explored in literature due to its complexity and importance in chemical and petrochemical industries. In this process, pressure represents one of the most important variables to be controlled. However, there are few studies about how pressure affects the dynamic behavior of distillation columns and most research on distillation column control involve direct manipulation of cooling fluid through the condenser. Nevertheless, such an approach demands constant changes in cooling fluid flowrates that are commonly by the order of tons per hour, which can be difficult to work or even unfeasible in a real plant. Furthermore, this strategy is usually avoided, as it can cause fouling and corrosion acceleration. The hot-vapor bypass strategy fits well as a solution for these issues, eliminating the need to dynamically manipulate cooling fluid flowrates in the condensation unit. This work presents the modeling and simulation of a conventional distillation column for the separation of water and ethanol, in which a comparative study between a conventional pressure control and a control using hot-vapor bypass was performed. The main results were obtained through dynamic simulations which considered various disturbances in the feed stream, and demonstrated superior performance by the hot-vapor bypass system over the usual scheme proposed in literature, while evaluating the lntegral Absolute Error (IAE) norm as the control performance index.展开更多
A Continuously Variable Transmission (CVT) is a type of transmissions that provides a continuous range of speed ratios, thus it allows increasing the overall powertrain efficiency by running the engine at the optimal ...A Continuously Variable Transmission (CVT) is a type of transmissions that provides a continuous range of speed ratios, thus it allows increasing the overall powertrain efficiency by running the engine at the optimal operating points. This paper investigates implementing a model based hydraulic pressure controller to achieve the desired CVT gear ratio. A map of desired gear ratios was estimated using the Optimal Operating Line (OOL) strategy, which minimizes the engine fuel consumption according to a defined cost function and a set of systems constraints. The controller was implemented in a complete vehicle model that includes driver, powertrain and road load models. The model was subjected to two different driving cycles and the results demonstrate the effectiveness of the control strategy and the pressure controller in keeping the engine at the most efficient operating regions.展开更多
In situ pressure-preserved coring(IPP-Coring)technology is considered one of the most efficient methods for assessing resources.However,seal failure caused by the rotation of pressure controllers greatly affects the s...In situ pressure-preserved coring(IPP-Coring)technology is considered one of the most efficient methods for assessing resources.However,seal failure caused by the rotation of pressure controllers greatly affects the success of pressure coring.In this paper,a novel spherical-cylindrical shell pressure controller was proposed.The finite element analysis model was used to analyze the stress distribution and deformation characteristics of the pressure controller at different rotation angles.The seal failure mechanism caused by the rotation of the pressure controller was discussed.The stress deviation rate was defined to quantitatively characterize the stress concentration.Based on the test equipment designed in this laboratory,the ultimate bearing strength of the pressure controller was tested.The results show that the rotation of the valve cover causes an increase in the deformation on its lower side.Furthermore,the specific sealing pressure in the weak zone is greatly reduced by a statistically significant amount,resulting in seal failure.When the valve cover rotates 5°around the major axis,the stress deviation rate is-92.6%.To prevent rotating failure of the pressure controller,it is necessary to control the rotation angle of the valve cover within 1°around the major axis.The results of this research can help engineers reduce failure-related accidents,provide countermeasures for pressure coring,and contribute to the exploration and evaluation of deep oil and gas resources.展开更多
Objective:Home blood pressure monitoring(HBPM)is viewed as a facilitating factor in the initial diagnosis and long-term management of treated hypertension.However,evidence remains scarce about the effectiveness of HBP...Objective:Home blood pressure monitoring(HBPM)is viewed as a facilitating factor in the initial diagnosis and long-term management of treated hypertension.However,evidence remains scarce about the effectiveness of HBPM use in the real world.This study aimed to examine the associations of HBPM use with blood pressure(BP)control and medication adherence.Methods:This prospective cohort study included hypertensive patients with high cardiovascular risk who were aged≥50 years.At baseline,information about types of BP monitor,frequency of HBPM,perception of anti-hypertensive treatment,and measured office BP were collected.During the 1-year follow-up(visits at 1,2,3,6,and 12 months),information on medication adherence was collected at each visit.The 2 major outcomes were BP control at baseline and medication adherence during the 1-year follow-up.A log-binomial regression model was used to examine the association between frequency of HBPM and outcomes,stratified by the perceptions of anti-hypertensive treatment.Results:A total of 5,363 hypertensive patients were included in the analysis.The age was(64.6±7.2)years,and 41.2%(2,208)were female.Of the total patients,85.9%(4,606)had a home BP monitor and 47.8%(2,564)had an incorrect perception of anti-hypertensive treatment.Overall,24.2%(1,299)of patients monitored their BP daily,37.6%(2,015)weekly,17.3%(926)monthly,and 20.9%(1,123)less than monthly.At baseline,the systolic BP and diastolic BP were(146.6±10.8)mmHg and(81.9±10.6)mmHg,respectively,and 28.5%(1,527)of patients had their BP controlled.Regardless of whether the patients had correct or incorrect perceptions of anti-hypertensive treatment,there is no significant association between HBPM frequency and BP control at baseline.During the 1-year follow-up,23.9%(1,280)of patients had non-adherence to medications at least once.In patients with an incorrect perception of anti-hypertensive treatment,those monitoring BP most frequently(daily)had the highest non-adherence rate(29.9%,175/585).Compared with those monitoring their BP less than monthly,patients who monitored their BP daily were more likely not to adhere to anti-hypertensive medications(adjusted relative risk=1.38,95%confidence interval:1.11–1.72,P=0.004).Conclusions:HBPM performance among hypertensive patients in China is,in general,sub-optimal.No association was observed between using HBPM alone and hypertension control,indicating that the effects of HBPM could be conditional.Patients’misconceptions about anti-hypertensive treatment may impair the role of BP monitoring in achieving medication adherence.Fully incorporating the correct perception of hypertension into the management of hypertensive patients is needed.展开更多
基金The authors are grateful for the financial support from the National Natural Science Foundation of China(No.51827901&No.52274133)the Program for Guangdong Introducing Innovative and Enterpreneurial Teams(No.2019ZT08G315)the Shenzhen National Science Fund for Distinguished Young Scholars(RCJC20210706091948015).
文摘In-situ pressure-preserved coring(IPP-Coring)is considered to be the most reliable and efficient method for the identification of the scale of oil and gas resources.During IPP-Coring,because the rotation behavior of the pressure controller valve cover in different medium environments is unclear,interference between the valve cover and inner pipe may occur and negatively affect the IPP-Coring success rate.To address this issue,we conducted a series of indoor experiments employing a high-speed camera to gain greater insights into the valve cover rotation behavior in different medium environments,e.g.,air,water,and simulated drilling fluids.The results indicated that the variation in the valve cover rotation angle in the air and fluid environments can be described by a one-phase exponential decay function with a constant time parameter and by biphasic dose response function,respectively.The rotation behavior in the fluid environments exhibited distinct elastic and gravitational acceleration zones.In the fluid environments,the density clearly impacted the valve cover closing time and rotation behavior,whereas the effect of viscosity was very slight.This can be attributed to the negligible influence of the fluid viscosity on the drag coefficient found in this study;meanwhile,the density can increase the buoyancy and the time period during which the valve cover experienced a high drag coefficient.Considering these results,control schemes for the valve cover rotation behavior during IPP-Coring were proposed for different layers and geological conditions in which the different drilling fluids should be used,e.g.,the use of a high-density valve cover in high-pore pressure layers.
基金The Project of the National Ministry of Industry and Information Technology[2020-0103-3-1-1]The Project of Beijing Science and technology“capital characteristics”[Z181100001718007]。
文摘Objective Current clinical evidence on the effects of home blood pressure telemonitoring(HBPT)on improving blood pressure control comes entirely from developed countries.Thus,we performed this randomized controlled trial to evaluate whether HBPT plus support(patient education and clinician remote hypertension management)improves blood pressure control more than usual care(UC)in the Chinese population.Methods This single-center,randomized controlled study was conducted in Beijing,China.Patients aged 30-75 years were eligible for enrolment if they had blood pressure[systolic(SBP)≥140 mmHg and/or diastolic(DBP)≥90 mmHg;or SBP≥130 mmHg and/or DBP≥80 mmHg with diabetes].We recruited 190 patients randomized to either the HBPT or the UC groups for 12 weeks.The primary endpoints were blood pressure reduction and the proportion of patients achieving the target blood pressure.Results Totally,172 patients completed the study,the HBPT plus support group(n=84),and the UC group(n=88).Patients in the plus support group showed a greater reduction in mean ambulatory blood pressure than those in the UC group.The plus support group had a significantly higher proportion of patients who achieved the target blood pressure and maintained a dipper blood pressure pattern at the12th week of follow-up.Additionally,the patients in the plus support group showed lower blood pressure variability and higher drug adherence than those in the UC group.Conclusion HBPT plus additional support results in greater blood pressure reduction,better blood pressure control,a higher proportion of dipper blood pressure patterns,lower blood pressure variability,and higher drug adherence than UC.The development of telemedicine may be the cornerstone of hypertension management in primary care.
基金supported by the National Natural Science Foundation of China(grant numbers 51827901,51805340)funded by the Program for Guangdong Introducing Innovative and Enterpreneurial Teams(No.2019ZT08G315)Shenzhen Basic Research Program(General Program)(No.JCYJ20190808153416970).
文摘Deep oil exploration coring technology cannot accurately maintain the in-situ pressure and temperature of samples, which leads to a distortion of deep oil and gas resource reserve evaluations based on conventional cores and cannot guide the development of deep oil and gas resources on Earth. The fundamental reason is the lack of temperature and pressure control in in-situ coring environments. In this paper, a pressure control method of a coring device is studied. The theory and method of deep intelligent temperature-pressure coupling control are innovatively proposed, and a multifield coupling dynamic sealing model is established. The optimal cardinality three term PID (Proportional-Integral-Differential) intelligent control algorithm of pressure system is developed. The temperature-pressure characteristic of the gas-liquid two-phase cavity is analyzed, and the pressure intelligent control is carried out based on three term PID control algorithms. An in-situ condition-preserved coring (ICP-Coring) device is developed, and an intelligent control system for the temperature and pressure of the coring device is designed and verified by experiments. The results show that the temperature-pressure coupling control system can effectively realize stable sealing under temperature-pressure fields of 140 MPa and 150 °C. The temperature-pressure coupling control method can accurately realize a constant pressure inside the coring device. The maximum working pressure is 140 MPa, and the effective pressure compensation range is 20 MPa. The numerical simulation experiment of pressure system control algorithm is carried out, and the optimal cardinality and three term coefficients are obtained. The pressure steady-state error is less than 0.01%. The method of temperature-pressure coupling control has guiding significance for coring device research, and is also the basis for temperature-pressure decoupling control in ICP-Coring.
文摘Introduction: The management of hypertension is mostly based on pharmacotherapy and hygienic and dietary measures (HDMs) for which little data is available in Cameroon. The concern to improve the quality of life of hypertensive patients led us to study the knowledge, compliance and effect of HDMs among Cameroonian hypertensive patients. Methods: This was a cross-sectional study carried out at the Douala General Hospital;the census of patients was carried out from 05 March to 10 May 2018. The data evaluated were knowledge and compliance with HDMs with an inference of their effect on blood pressure control. Results: We recruited 330 participants at mean age of 60 ± 11 years, 37.9% men;57.3% with blood pressure (BP) controlled. Out of 330 subjects, 308 (93.3%) who had been educated about dietary health measures for hypertension were assessed on knowledge, compliance and effect of these measures against 22 (6.7%) who had never heard about them. Around 85.7% of participants had good knowledge of HDMs and 78.9% had good compliance with them. There was no statistically significant influence of knowledge and compliance with HDMs on blood pressure control. Conclusion: The level of knowledge and adherence to HDMs of hypertensive patients at the Douala General Hospital was appreciable. It is however appropriate for physicians to intensify patient education on HDMs and BP control.
文摘Objective:To explore the risk factors of diabetic nephropathy and its correlation with blood pressure control.Methods:A retrospective analysis of 80 patients with diabetic nephropathy(diabetic nephropathy group)and another 80 patients with diabetes(diabetic group)who were admitted to the Department of Nephrology and Endocrinology at our hospital from October 2021 to October 2022 was conducted.The general data of the two groups were compared,the influencing factors associated with the two groups were analyzed unilaterally,and unconditional dichotomous logistic regression was performed to analyze the influencing factors in patients with diabetic nephropathy.Results:There were no significant differences in high-density lipoprotein,systolic blood pressure,diastolic blood pressure,and creatinine between the two groups(P>0.05);however,compared with the diabetic group,the DN group had significantly elevated glycated hemoglobin,low-density lipoprotein,24-h urine protein,insulin resistance,and diabetes duration≥10 years(P<0.05).Conclusion:The clinical research on the correlation between the incidence of hypertension and the control of blood pressure in patients with diabetic nephropathy should be strengthened in order to formulate reasonable and feasible treatment plans.
文摘This paper describes a supervisory hierarchical fuzzy controller (SHFC) for regulating pressure in a real-time pilot pressure control system. The input scaling factor tuning of a direct expert controller is made using the error and process input parameters in a closed loop system in order to obtain better controller performance for set-point change and load disturbances. This on-line tuning method reduces operator involvement and enhances the controller performance to a wide operating range. The hierarchical control scheme consists of an intelligent upper level supervisory fuzzy controller and a lower level direct fuzzy controller. The upper level controller provides a mechanism to the main goal of the system and the lower level controller delivers the solutions to a particular situation. The control algorithm for the proposed scheme has been developed and tested using an ARM7 microcontroller-based embedded target board for a nonlinear pressure process having dead time. To demonstrate the effectiveness, the results of the proposed hierarchical controller, fuzzy controller and conventional proportional-integral (PI) controller are analyzed. The results prove that the SHFC performance is better in terms of stability and robustness than the conventional control methods.
基金supported by National Natural Science Foundation of China (Grant No. 50775199)National Hi-tech Research and Development Program of China (863 Program,Grant No. 2008AA042703)
文摘Water-assisted injection molding(WAIM),a newly developed fluid-assisted injection molding technology has drawn more and more attentions for the energy saving,short cooling circle time and high quality of products.Existing research for the process of WAIM has shown that the pressure control of the injecting water is mostly important for the WAIM.However,the proportional pressure control for the WAIM system is quite complex due to the existence of nonlinearities in the water hydraulic system.In order to achieve better pressure control performance of the injecting water to meet the requirements of the WAIM,the proportional pressure control of the WAIM system is investigated both numerically and experimentally.A newly designed water hydraulic system for WAIM is first modeled in AMEsim environment,the load characteristics and the nonlinearities of water hydraulic system are both considered,then the main factors affecting the injecting pressure and load flow rate are extensively studied.Meanwhile,an open-loop model-based compensation control strategy is employed to regulate the water injection pressure and a feedback proportional integrator controller is further adopted to achieve better control performance.In order to verify the AMEsim simulation results WAIM experiment for particular Acrylonitrile Butadiene Styrene(ABS) parts is implemented and the measured experimental data including injecting pressure and flow rate results are compared with the simulation.The good coincidence between experiment and simulation shows that the AMEsim model is accurate,and the tracking performance of the load pressure indicates that the proposed control strategy is effective for the proportional pressure control of the nonlinear WAIM system.The proposed proportional pressure control strategy and the conclusions drawn from simulation and experiment contribute to the application of water hydraulic proportional control and WAIM technology.
文摘The performance of the designed digital electro-pneumatic cabin pressure control system for the cabin pressure schedule of transport aircraft is investigated.For the purpose of this study,an experimental setup consisting of a simulated hermetic cabin and altitude simulation chamber is configured for cabin pressure control system operation.A series of experimental tests are executed to evaluate the performance of the cabin pressure control system.The parameters of the PID controller are optimized.In the optimization process,the variation regularity of the rate of cabin pressure change under various conditions is considered.An approach to prioritize the control of the rate of change of cabin pressure based on the flight status model is proposed and verified experimentally.The experimental results indicate that the proposed approach can be adopted for the designed digital electro-pneumatic cabin pressure control system to obtain a better cabin pressure schedule and rate of cabin pressure change.
基金Supported by the National Natural Science Foundation of China(No.51575471)the Key Project of Science and Technology Plan of Higher Education of Hebei Education Department(No.ZD2017077)
文摘Multi-level pressure source system is a novel hydraulic system with distinct advantage of energy saving. In order to balance each pressure level of the multi-level pressure source system, a pump motor energy transfer unit is usually equipped. However, the pump motor energy transfer has the characteristics of poor starting and low response, which cause long time of pressure adjustment and large pressure jitter when the transformer is switched to system suddenly and the motor-side pressure has pressure impact when rail of the pump-side is switched. To address these problems, this paper proposes a compound control strategy of feedforward compensation control with Fuzzy-PID to improve the controllability of the multi-level pressure source system. A test rig of the pump motor energy transfer unit is built and the controllability of compound controller and PID controller are compared. The experiment results show that, compared with the traditional PID, the adjustment time and the pressure impact are reduced by 20% and 25% with the proposed compound control strategy. Therefore, the presented compound control strategy can be used to improve starting performance and robustness of the pump motor energy transfer unit control system.
基金Supported by the National High Technology Research and Development Program of China(863 Program)(2012AA110903)Jilin Key Scientific and Technological Project(20170204085GX)Jilin Industrial Technology Innovation Strategic Alliance Program(20150309013GX)
文摘In this paper the control mechanism of solenoid valve is analyzed,which shows the solenoid valve control is actually the control of coil current.The response characteristic of coil current is related to coil inductance and resistance.The coil resistance is influenced greatly by the ambient temperature and the self-heating of coil,which affects the control precision of coil current.First,considering the heat dissipation mode of coil,the coil temperature model is established from the perspective of heat conduction,and a temperature compensation algorithm for hydraulic system pressure control is put forward.Then the hardware-in-the-loop testbed is set up by using the dSPACE platform,carrying out wheel cylinder pressurization tests with inlet valve fully opened at-40℃ and 20℃,and testing the actual pressure of wheel cylinder with the target pressures at-40℃ and 6 000 kPa/s(pressurization rate).The results show that the pressure control temperature compensation algorithm proposed in this paper accurately corrects the influence of resistance temperature drift on the response accuracy of wheel cylinder pressure.After the correction,the pressure difference is less than 500 kPa,which can meet the control accuracy requirements of solenoid valve,enriching the linear control characteristic of solenoid valve.
文摘A pressurizer is one of important equipment in a pressurized water reactor plant. It is used to maintain the pressure of primary coolant within allowed range because the sharp change of coolant pressure affects the security of reactor, therefor, the study of pressurizer’s pressure control methods is very important. In this paper, an adaptive fuzzy controller is presented for pressure control of a presurizer in a nuclear power plant. The controller can on-line tune fuzzy control rules and parameters by self-learning in the actual control process, which possesses the way of thinking like human to make a decision. The simulation results for a pressurized water reactor plant show that the adaptive fuzzy controller has optimum and intelligent characteristics, which prove the controller is effective.
文摘It is very important to maintain the level of mean arterial pressure (MAP). The MAP control is applied in many clinical situations, including limiting bleeding during cardiac surgery and promoting healing for patient' s post-surgery. This paper presents a fuzzy controller-based multiple-model adaptive control system for postoperative blood pressure management. Multiple-model adaptive control (MMAC) algorithm is used to identify the patient model, and it is a feasible system identification method even in the presence of large noise. Fuzzy control (FC) method is used to design controller bank. Each fuzzy controller in the controller bank is in fact a nonlinear proportional-integral (PI) controller,whose proportional gain and integral gain are adjusted continuously according to error and rate of change of error of the plant output, resulting in better dynamic and stable control performance than the regular PI controller, especially when a nonlinear process is involved. For demonstration, a nonlinear, pulsatile-flow patient model is used for simulation, and the results show that the adaptive control system can effectively handle the changes in patient's dynamics and provide satisfactory performance in regulation of blood pressure of hypertension patients.
基金This work was supported by the National Key R&D Program of China(Grant 2017YFE0117100)the National Natural Science Foundation of China(Grants 11872040 and 11232010)+1 种基金the Outstanding Clinical Discipline Project of Shanghai Pudong(Grant PWYgy-2018-08)the Science and Technology Commission of Shanghai Municipality(Grant 18ZR1433900).
文摘Acute stress concentration plays an important role in plaque rupture and may cause stroke or myocardial infarction.Quantitative evaluation of the relation between in vivo plaque stress and variations in blood pressure and flow rates is valuable to optimize daily monitoring of the cardiovascular system for high-risk patients as well as to set a safe physical exercise intensity for better quality of life.In this study,we constructed an in vivo stress model for a human carotid bifurcation with atherosclerotic plaque,and analyzed the effects of blood pressure,flow rates,plaque stiffness,and stenosis on the elastic stress and fluid viscous stress around the plaque.According to the maximum values of the mechanical stress,we define a risk index to predict the risk level of plaque rupture under different exercise intensities.For a carotid bifurcation where the blood flow divides,the results suggest that the stenosis ratio determines the ratio of the contributions of elastic shear stress and viscous shear stress to plaque rupture.A n increase of the plaque stiffness enhances the maximum elastic shear stress in the plaque,indicating that a high-stiffness plaque is more prone to rupture for given stenosis ratio.High stress co-localization at the shoulder of plaques agrees with the region of plaque injury in clinical observations.It is demonstrated that,due to the stress-shield effect,the rupture risk of a high-stiffness plaque tends to decrease under high-stenosis conditions,suggesting the existence of a specific stenosis corresponding to the maximum risk.This study may help to complement risk stratification of vulnerable plaques in clinical practice and provides a stenosis mechanical property-specific guide for blood pressure control in cardiovascular health management.
基金Project(2012AA041801)supported by the High-tech Research and Development Program of China
文摘A nonlinear pressure controller was presented to track desired feeding pressure for the cutter feeding system(CFS) of trench cutter(TC) in the presence of unknown external disturbances.The feeding pressure control of CFS is subjected to unknown load characteristics of rock or soil; in addition,the geological condition is time-varying.Due to the complex load characteristics of rock or soil,the feeding velocity of TC is related to geological conditions.What is worse,its dynamic model is subjected to uncertainties and its function is unknown.To deal with the particular characteristics of CFS,a novel adaptive fuzzy integral sliding mode control(AFISMC) was designed for feeding pressure control of CFS,which combines the robust characteristics of an integral sliding mode controller and the adaptive adjusting characteristics of an adaptive fuzzy controller.The AFISMC feeding pressure controller is synthesized using the backstepping technique.The stability of the overall closed-loop system consisting of the adaptive fuzzy inference system,integral sliding mode controller and the cutter feeding system is proved using Lyapunov theory.Experiments are conducted on a TC test bench with the AFISMC under different operating conditions.The experimental results demonstrate that the proposed AFISMC feeding pressure controller for CFS gives a superior and robust pressure tracking performance with maximum pressure tracking error within ?0.3 MPa.
文摘This paper presents a technique for controlling the pressure of a molten metal when using a new type of iron casting method called sand mold press casting to realize high productivity and obtain high-quality products.The past test results using this method showed a casting yield of 90% to 95%,while conventional methods only show a casting yield of 60% to 70%.Although the press casting method does not require a sprue cup or runner channel casting defects such as metal penetration are often caused by the high pressure in the high-velocity pressing part of this casting process.Therefore,we proposed a pressure control method with a mathematical model of molten metal pressure,and with it we achieved experimental confirmation of the successful production of brake drums at different pressing temperatures.Results show that the proposed pressing control method can realize sound,penetration-free casting production.However,the theoretical analysis and design of this pressing process had not previously been studied sufficiently,and therefore this paper presents the theoretical design algorithm for the process as well as its experimental confirmation.
基金Project supported by National High-Technology Research andDevelopment Program of China (Grant No .2002AA517020)
文摘Control design is important for PEMFC (proton exchange membrane fuel cell) distributed power generator to satisfy user requirement for safe and stable operation. For a complex multi-variable dynamic system, a dynamic simulation model is first established. In view of close coupling and non-linear relationships between variables, the intelligent auto-adapted PI decoupling control method is used. From the simulation results it is found that, by bringing quadratic performance index in the single neuron, constructing adaptive PI controller, and adjusting gas flow rates through the second pressure relief valve and air compressor coordinately, both anode and cathode pressures can be maintained at ideal levels.
基金the Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)for financial support for this work
文摘Distillation column control is widely explored in literature due to its complexity and importance in chemical and petrochemical industries. In this process, pressure represents one of the most important variables to be controlled. However, there are few studies about how pressure affects the dynamic behavior of distillation columns and most research on distillation column control involve direct manipulation of cooling fluid through the condenser. Nevertheless, such an approach demands constant changes in cooling fluid flowrates that are commonly by the order of tons per hour, which can be difficult to work or even unfeasible in a real plant. Furthermore, this strategy is usually avoided, as it can cause fouling and corrosion acceleration. The hot-vapor bypass strategy fits well as a solution for these issues, eliminating the need to dynamically manipulate cooling fluid flowrates in the condensation unit. This work presents the modeling and simulation of a conventional distillation column for the separation of water and ethanol, in which a comparative study between a conventional pressure control and a control using hot-vapor bypass was performed. The main results were obtained through dynamic simulations which considered various disturbances in the feed stream, and demonstrated superior performance by the hot-vapor bypass system over the usual scheme proposed in literature, while evaluating the lntegral Absolute Error (IAE) norm as the control performance index.
文摘A Continuously Variable Transmission (CVT) is a type of transmissions that provides a continuous range of speed ratios, thus it allows increasing the overall powertrain efficiency by running the engine at the optimal operating points. This paper investigates implementing a model based hydraulic pressure controller to achieve the desired CVT gear ratio. A map of desired gear ratios was estimated using the Optimal Operating Line (OOL) strategy, which minimizes the engine fuel consumption according to a defined cost function and a set of systems constraints. The controller was implemented in a complete vehicle model that includes driver, powertrain and road load models. The model was subjected to two different driving cycles and the results demonstrate the effectiveness of the control strategy and the pressure controller in keeping the engine at the most efficient operating regions.
基金supported by the Program for Guangdong Introducing Innovative and Enterpreneurial Teams(No.2019ZT08G315)National Natural Science Foundation of China No.51827901 and U2013603
文摘In situ pressure-preserved coring(IPP-Coring)technology is considered one of the most efficient methods for assessing resources.However,seal failure caused by the rotation of pressure controllers greatly affects the success of pressure coring.In this paper,a novel spherical-cylindrical shell pressure controller was proposed.The finite element analysis model was used to analyze the stress distribution and deformation characteristics of the pressure controller at different rotation angles.The seal failure mechanism caused by the rotation of the pressure controller was discussed.The stress deviation rate was defined to quantitatively characterize the stress concentration.Based on the test equipment designed in this laboratory,the ultimate bearing strength of the pressure controller was tested.The results show that the rotation of the valve cover causes an increase in the deformation on its lower side.Furthermore,the specific sealing pressure in the weak zone is greatly reduced by a statistically significant amount,resulting in seal failure.When the valve cover rotates 5°around the major axis,the stress deviation rate is-92.6%.To prevent rotating failure of the pressure controller,it is necessary to control the rotation angle of the valve cover within 1°around the major axis.The results of this research can help engineers reduce failure-related accidents,provide countermeasures for pressure coring,and contribute to the exploration and evaluation of deep oil and gas resources.
基金supported by the National Key Research and Development Program of China(2018YFC1312404,2018YFC1312400)by the National Clinical Research Center for Cardiovascular Diseases,Fuwai Hospital,Chinese Academy of Medical Sciences(NCRC2021001).
文摘Objective:Home blood pressure monitoring(HBPM)is viewed as a facilitating factor in the initial diagnosis and long-term management of treated hypertension.However,evidence remains scarce about the effectiveness of HBPM use in the real world.This study aimed to examine the associations of HBPM use with blood pressure(BP)control and medication adherence.Methods:This prospective cohort study included hypertensive patients with high cardiovascular risk who were aged≥50 years.At baseline,information about types of BP monitor,frequency of HBPM,perception of anti-hypertensive treatment,and measured office BP were collected.During the 1-year follow-up(visits at 1,2,3,6,and 12 months),information on medication adherence was collected at each visit.The 2 major outcomes were BP control at baseline and medication adherence during the 1-year follow-up.A log-binomial regression model was used to examine the association between frequency of HBPM and outcomes,stratified by the perceptions of anti-hypertensive treatment.Results:A total of 5,363 hypertensive patients were included in the analysis.The age was(64.6±7.2)years,and 41.2%(2,208)were female.Of the total patients,85.9%(4,606)had a home BP monitor and 47.8%(2,564)had an incorrect perception of anti-hypertensive treatment.Overall,24.2%(1,299)of patients monitored their BP daily,37.6%(2,015)weekly,17.3%(926)monthly,and 20.9%(1,123)less than monthly.At baseline,the systolic BP and diastolic BP were(146.6±10.8)mmHg and(81.9±10.6)mmHg,respectively,and 28.5%(1,527)of patients had their BP controlled.Regardless of whether the patients had correct or incorrect perceptions of anti-hypertensive treatment,there is no significant association between HBPM frequency and BP control at baseline.During the 1-year follow-up,23.9%(1,280)of patients had non-adherence to medications at least once.In patients with an incorrect perception of anti-hypertensive treatment,those monitoring BP most frequently(daily)had the highest non-adherence rate(29.9%,175/585).Compared with those monitoring their BP less than monthly,patients who monitored their BP daily were more likely not to adhere to anti-hypertensive medications(adjusted relative risk=1.38,95%confidence interval:1.11–1.72,P=0.004).Conclusions:HBPM performance among hypertensive patients in China is,in general,sub-optimal.No association was observed between using HBPM alone and hypertension control,indicating that the effects of HBPM could be conditional.Patients’misconceptions about anti-hypertensive treatment may impair the role of BP monitoring in achieving medication adherence.Fully incorporating the correct perception of hypertension into the management of hypertensive patients is needed.