In transportation cyber-physical-systems (T-CPS), vehicle-to-vehicle (V2V) communications play an important role in the coordination between individual vehicles as well as between vehicles and the roadside infrast...In transportation cyber-physical-systems (T-CPS), vehicle-to-vehicle (V2V) communications play an important role in the coordination between individual vehicles as well as between vehicles and the roadside infrastructures, and engine cylinder pressure is significant for engine diagnosis on-line and torque control within the information exchange process under V2V communications. However, the parametric uncertainties caused from measurement noise in T-CPS lead to the dynamic performance deterioration of the engine cylinder pressure estimation. Considering the high accuracy requirement under V2V communications, a high gain observer based on the engine dynamic model is designed to improve the accuracy of pressure estimation. Then, the analyses about convergence, converge speed and stability of the corresponding error model are conducted using the Laplace and Lyapunov method. Finally, results from combination of Simulink with GT- Power based numerical experiments and comparisons demonstrate the effectiveness of the proposed approach with respect to robustness and accuracy.展开更多
Portal hypertension(PH)is a clinical syndrome,characterized by elevated pressure gradient between portal vein and inferior vena cava.These elevated pressures gradient due to increased vascular resistance and/or increa...Portal hypertension(PH)is a clinical syndrome,characterized by elevated pressure gradient between portal vein and inferior vena cava.These elevated pressures gradient due to increased vascular resistance and/or increased volume of blood flowing through the portal vein circulation,results in blood outflow difficulty from portal vein to hepatic veins and inferior vena cava.展开更多
Blood pressure(BP)is an important indicator of individuals’health conditions for the prevention or treatment of cardiovascular disease.However,conventional measurements require inconvenient cuffbased instruments and ...Blood pressure(BP)is an important indicator of individuals’health conditions for the prevention or treatment of cardiovascular disease.However,conventional measurements require inconvenient cuffbased instruments and are not able to detect continuous blood pressure.Advanced methods utilize machine learning to estimate BP by constructing artificial features in plethysmography(PPG)or using an end-to-end deep learning framework to estimate BP directly.Empirical features are limited by current research on cardiovascular disease and are not sufficient to express BP variability,while data-driven approaches neglect expert knowledge and lack interpretability.To address this issue,in this paper we propose a method for continuous BP estimation that extracts both artificial and data-driven features from PPG to take advantage of expert knowledge and deep learning at the same time.Then a deep residual neural network is designed to reduce information redundancy in the gathered features and refine high-level features for BP estimation.The results show that our proposed methods outperforms the compared methods in three commonly used metrics.展开更多
Background Transthoracic Doppler echocardiography is recommended for screening the presence of pulmonary hypertension(PH).However,the accuracy of pulmonary artery systolic pressure(PASP) estimated by Doppler echocardi...Background Transthoracic Doppler echocardiography is recommended for screening the presence of pulmonary hypertension(PH).However,the accuracy of pulmonary artery systolic pressure(PASP) estimated by Doppler echocardiographic is still unknown.Methods We conducted a retrospective study on 102 patients with idiopathic pulmonary arterial hypertension who underwent Doppler echocar-diography within 72 hours before right heart catheterization. During this time,all patients were stable without any specific drug therapy.Results There was moderate correlation between Doppler echocardiographic and right heart catheteriza- tion measurements of PASP(r =0.642,P【0.001).Using Bland-Altman analytic methods,the bias for the echocardio-graphic estimates of PASP was 6.65 mm Hg with 95%limits of agreement ranging from -47.62 to 34.30 mm Hg.There were 58.8%cases with absolute differences over 10 mm Hg between the two methods.Overestimation and underestimation of PASP by Doppler echocardiography occurred in 15.7% (16/102) and 43.1%(44),respectively.The magnitude of pressure underestimation and overestimation was insignificant (24.52±12.15 vs.25.69±16.09,P=0.765),while the corresponding diagnostic categories of severity that each subject would fall into for each technique are not in good agreement. The diagnostic categories of 16 overestimated patients were in accordance.During 44 underestimated patients,20.5%of patients had their pressure underestimated within one diagnostic category(minor error);4.5%of the underestimates were with two diagnostic categories(major error).Conclusions Transthoracic Doppler echocardiography may frequently be inaccurate in estimating PASP and could not replace the right heart catheterization.展开更多
In today's modern electric vehicles,enhancing the safety-critical cyber-physical system(CPS)'s performance is necessary for the safe maneuverability of the vehicle.As a typical CPS,the braking system is crucia...In today's modern electric vehicles,enhancing the safety-critical cyber-physical system(CPS)'s performance is necessary for the safe maneuverability of the vehicle.As a typical CPS,the braking system is crucial for the vehicle design and safe control.However,precise state estimation of the brake pressure is desired to perform safe driving with a high degree of autonomy.In this paper,a sensorless state estimation technique of the vehicle's brake pressure is developed using a deep-learning approach.A deep neural network(DNN)is structured and trained using deep-learning training techniques,such as,dropout and rectified units.These techniques are utilized to obtain more accurate model for brake pressure state estimation applications.The proposed model is trained using real experimental training data which were collected via conducting real vehicle testing.The vehicle was attached to a chassis dynamometer while the brake pressure data were collected under random driving cycles.Based on these experimental data,the DNN is trained and the performance of the proposed state estimation approach is validated accordingly.The results demonstrate high-accuracy brake pressure state estimation with RMSE of 0.048 MPa.展开更多
The first automatic algorithm was designed to estimate the pulse pressure variation (PPVPPV) from arterial blood pressure (ABP) signals under spontaneous breathing conditions. While currently there are a few publicly ...The first automatic algorithm was designed to estimate the pulse pressure variation (PPVPPV) from arterial blood pressure (ABP) signals under spontaneous breathing conditions. While currently there are a few publicly available algorithms to automatically estimate PPVPPV accurately and reliably in mechani-cally ventilated subjects, at the moment there is no automatic algorithm for estimating PPVPPV on sponta-neously breathing subjects. The algorithm utilizes our recently developed sequential Monte Carlo method (SMCM), which is called a maximum a-posteriori adaptive marginalized particle filter (MAM-PF). The performance assessment results of the proposed algorithm on real ABP signals from spontaneously breath-ing subjects were reported.展开更多
The problem of air-fuel ratio(AFR) control of the port injection spark ignition(SI) engine is still of considerable importance because of stringent demands on emission control. In this paper, the static AFR calculatio...The problem of air-fuel ratio(AFR) control of the port injection spark ignition(SI) engine is still of considerable importance because of stringent demands on emission control. In this paper, the static AFR calculation model based on in-cylinder pressure data and on the adaptive AFR control strategy is presented. The model utilises the intake manifold pressure, engine speed, total heat release, and the rapid burn angle, as input variables for the AFR computation. The combustion parameters, total heat release,and rapid burn angle, are calculated from in-cylinder pressure data. This proposed AFR model can be applied to the virtual lambda sensor for the feedback control system. In practical applications, simple adaptive control(SAC) is applied in conjunction with the AFR model for port-injected fuel control. The experimental results show that the proposed model can estimate the AFR, and the accuracy of the estimated value is applicable to the feedback control system. Additionally, the adaptive controller with the AFR model can be applied to regulate the AFR of the port injection SI engine.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.61304197)the Scientific and Technological Talents of Chongqing,China(Grant No.cstc2014kjrc-qnrc30002)+2 种基金the Key Project of Application and Development of Chongqing,China(Grant No.cstc2014yykf B40001)the Natural Science Funds of Chongqing,China(Grant No.cstc2014jcyj A60003)the Doctoral Start-up Funds of Chongqing University of Posts and Telecommunications,China(Grant No.A2012-26)
文摘In transportation cyber-physical-systems (T-CPS), vehicle-to-vehicle (V2V) communications play an important role in the coordination between individual vehicles as well as between vehicles and the roadside infrastructures, and engine cylinder pressure is significant for engine diagnosis on-line and torque control within the information exchange process under V2V communications. However, the parametric uncertainties caused from measurement noise in T-CPS lead to the dynamic performance deterioration of the engine cylinder pressure estimation. Considering the high accuracy requirement under V2V communications, a high gain observer based on the engine dynamic model is designed to improve the accuracy of pressure estimation. Then, the analyses about convergence, converge speed and stability of the corresponding error model are conducted using the Laplace and Lyapunov method. Finally, results from combination of Simulink with GT- Power based numerical experiments and comparisons demonstrate the effectiveness of the proposed approach with respect to robustness and accuracy.
基金Sino-German Mobility Programme of NSFC and DFG,Grant/Award Number:M-0504National Natural Science Foundation of China,Grant/Award Numbers:82071942,82272013+1 种基金Shanghai Pujiang Program,Grant/Award Number:2020PJD008Clinical Research Plan of SHDC,Grant/Award Numbers:SHDC2020CR1031B,SHDC2020CR4060。
文摘Portal hypertension(PH)is a clinical syndrome,characterized by elevated pressure gradient between portal vein and inferior vena cava.These elevated pressures gradient due to increased vascular resistance and/or increased volume of blood flowing through the portal vein circulation,results in blood outflow difficulty from portal vein to hepatic veins and inferior vena cava.
文摘Blood pressure(BP)is an important indicator of individuals’health conditions for the prevention or treatment of cardiovascular disease.However,conventional measurements require inconvenient cuffbased instruments and are not able to detect continuous blood pressure.Advanced methods utilize machine learning to estimate BP by constructing artificial features in plethysmography(PPG)or using an end-to-end deep learning framework to estimate BP directly.Empirical features are limited by current research on cardiovascular disease and are not sufficient to express BP variability,while data-driven approaches neglect expert knowledge and lack interpretability.To address this issue,in this paper we propose a method for continuous BP estimation that extracts both artificial and data-driven features from PPG to take advantage of expert knowledge and deep learning at the same time.Then a deep residual neural network is designed to reduce information redundancy in the gathered features and refine high-level features for BP estimation.The results show that our proposed methods outperforms the compared methods in three commonly used metrics.
文摘Background Transthoracic Doppler echocardiography is recommended for screening the presence of pulmonary hypertension(PH).However,the accuracy of pulmonary artery systolic pressure(PASP) estimated by Doppler echocardiographic is still unknown.Methods We conducted a retrospective study on 102 patients with idiopathic pulmonary arterial hypertension who underwent Doppler echocar-diography within 72 hours before right heart catheterization. During this time,all patients were stable without any specific drug therapy.Results There was moderate correlation between Doppler echocardiographic and right heart catheteriza- tion measurements of PASP(r =0.642,P【0.001).Using Bland-Altman analytic methods,the bias for the echocardio-graphic estimates of PASP was 6.65 mm Hg with 95%limits of agreement ranging from -47.62 to 34.30 mm Hg.There were 58.8%cases with absolute differences over 10 mm Hg between the two methods.Overestimation and underestimation of PASP by Doppler echocardiography occurred in 15.7% (16/102) and 43.1%(44),respectively.The magnitude of pressure underestimation and overestimation was insignificant (24.52±12.15 vs.25.69±16.09,P=0.765),while the corresponding diagnostic categories of severity that each subject would fall into for each technique are not in good agreement. The diagnostic categories of 16 overestimated patients were in accordance.During 44 underestimated patients,20.5%of patients had their pressure underestimated within one diagnostic category(minor error);4.5%of the underestimates were with two diagnostic categories(major error).Conclusions Transthoracic Doppler echocardiography may frequently be inaccurate in estimating PASP and could not replace the right heart catheterization.
文摘In today's modern electric vehicles,enhancing the safety-critical cyber-physical system(CPS)'s performance is necessary for the safe maneuverability of the vehicle.As a typical CPS,the braking system is crucial for the vehicle design and safe control.However,precise state estimation of the brake pressure is desired to perform safe driving with a high degree of autonomy.In this paper,a sensorless state estimation technique of the vehicle's brake pressure is developed using a deep-learning approach.A deep neural network(DNN)is structured and trained using deep-learning training techniques,such as,dropout and rectified units.These techniques are utilized to obtain more accurate model for brake pressure state estimation applications.The proposed model is trained using real experimental training data which were collected via conducting real vehicle testing.The vehicle was attached to a chassis dynamometer while the brake pressure data were collected under random driving cycles.Based on these experimental data,the DNN is trained and the performance of the proposed state estimation approach is validated accordingly.The results demonstrate high-accuracy brake pressure state estimation with RMSE of 0.048 MPa.
文摘The first automatic algorithm was designed to estimate the pulse pressure variation (PPVPPV) from arterial blood pressure (ABP) signals under spontaneous breathing conditions. While currently there are a few publicly available algorithms to automatically estimate PPVPPV accurately and reliably in mechani-cally ventilated subjects, at the moment there is no automatic algorithm for estimating PPVPPV on sponta-neously breathing subjects. The algorithm utilizes our recently developed sequential Monte Carlo method (SMCM), which is called a maximum a-posteriori adaptive marginalized particle filter (MAM-PF). The performance assessment results of the proposed algorithm on real ABP signals from spontaneously breath-ing subjects were reported.
文摘The problem of air-fuel ratio(AFR) control of the port injection spark ignition(SI) engine is still of considerable importance because of stringent demands on emission control. In this paper, the static AFR calculation model based on in-cylinder pressure data and on the adaptive AFR control strategy is presented. The model utilises the intake manifold pressure, engine speed, total heat release, and the rapid burn angle, as input variables for the AFR computation. The combustion parameters, total heat release,and rapid burn angle, are calculated from in-cylinder pressure data. This proposed AFR model can be applied to the virtual lambda sensor for the feedback control system. In practical applications, simple adaptive control(SAC) is applied in conjunction with the AFR model for port-injected fuel control. The experimental results show that the proposed model can estimate the AFR, and the accuracy of the estimated value is applicable to the feedback control system. Additionally, the adaptive controller with the AFR model can be applied to regulate the AFR of the port injection SI engine.