Effect of Home Blood Pressure Telemonitoring Plus Additional Support on Blood Pressure Control:A Randomized Clinical Trial

Objective Current clinical evidence on the effects of home blood pressure telemonitoring(HBPT)on improving blood pressure control comes entirely from developed countries.Thus,we performed this randomized controlled trial to evaluate whether HBPT plus support(patient education and clinician remote hypertension management)improves blood pressure control more than usual care(UC)in the Chinese population.Methods This single-center,randomized controlled study was conducted in Beijing,China.Patients aged 30-75 years were eligible for enrolment if they had blood pressure[systolic(SBP)≥140 mmHg and/or diastolic(DBP)≥90 mmHg;or SBP≥130 mmHg and/or DBP≥80 mmHg with diabetes].We recruited 190 patients randomized to either the HBPT or the UC groups for 12 weeks.The primary endpoints were blood pressure reduction and the proportion of patients achieving the target blood pressure.Results Totally,172 patients completed the study,the HBPT plus support group(n=84),and the UC group(n=88).Patients in the plus support group showed a greater reduction in mean ambulatory blood pressure than those in the UC group.The plus support group had a significantly higher proportion of patients who achieved the target blood pressure and maintained a dipper blood pressure pattern at the12th week of follow-up.Additionally,the patients in the plus support group showed lower blood pressure variability and higher drug adherence than those in the UC group.Conclusion HBPT plus additional support results in greater blood pressure reduction,better blood pressure control,a higher proportion of dipper blood pressure patterns,lower blood pressure variability,and higher drug adherence than UC.The development of telemedicine may be the cornerstone of hypertension management in primary care.

The Impact of Different Mining and Releasing Ratios on the Over-Support Pressure of Header Working Face

Through the theoretical analysis of overburden destabilization mechanism, FLAC 3D simplified plane numerical simulation method and field measurement method, we compared the relationship of overburden support pressure at 35 m of workface recovery, and the peak overburden support pressure decreased from 13.85 Mpa to 11.97 Mpa from 1:1 to 1:3. With the increase of mining ratio, the peak over-supporting pressure decreases: with the increase of top coal recovery thickness, the peak over-supporting pressure and the influence range will be further expanded, and the distance between the peak over-supporting pressure and the coal wall of the working face will be further increased and the high stress zone of the peak area will be expanded simultaneously.

Influence of dynamic pressure on deep underground soft rock roadway support and its application

Due to high ground stress and mining disturbance, the deformation and failure of deep soft rock roadway is serious, and invalidation of the anchor net-anchor cable supporting structure occurs. The failure characteristics of roadways revealed with the help of the ground pressure monitoring. Theoretical analysis was adopted to analyze the influence of mining disturbance on stress distribution in surrounding rock,and the change of stress was also calculated. Considering the change of stress in surrounding rock of bottom extraction roadway, the displacement, plastic zone and distribution law of principal stress difference under different support schemes were studied by means of FLAC3D. The supporting scheme of U-shaped steel was proposed for bottom extraction roadway that underwent mining disturbance. We carried out a similarity model test to verify the effect of support in dynamic pressure. Monitoring results demonstrated the change rules of deformation and stress of surrounding rock in different supporting schemes. The supporting scheme of U-shaped steel had an effective control on deformation of surrounding rock. The scheme was successfully applied in underground engineering practice, and achieved good technical and economic benefits.

Analysis of the interaction between bolt-reinforced rock and surface support in tunnels based on convergence-confinement method

To investigate the interaction of the bolt-reinforced rock and the surface support,an analytical model of the convergence-confinement type is proposed,considering the sequential installation of the fully grouted rockbolts and the surface support.The rock mass is assumed to be elastic-brittle-plastic material,obeying the linear Mohr-Coulomb criterion or the non-linear Hoek-Brown criterion.According to the strain states of the tunnel wall at bolt and surface support installation and the relative magnitude between the bolt length and the plastic depth during the whole process,six cases are categorized upon solving the problem.Each case is divided into three stages due to the different effects of the active rockbolts and the passive surface support.The fictitious pressure is introduced to quantify the threedimensional(3D)effect of the tunnel face,and thus,the actual physical location along the tunnel axis of the analytical section can be considered.By using the bolt-rock strain compatibility and the rocksurface support displacement compatibility conditions,the solutions of longitudinal tunnel displacement and the reaction pressure of surface support along the tunnel axis are obtained.The proposed analytical solutions are validated by a series of 3D numerical simulations.Extensive parametric studies are conducted to examine the effect of the typical parameters of rockbolts and surface support on the tunnel displacement and the reaction pressure of the surface support under different rock conditions.The results show that the rockbolts are more effective in controlling the tunnel displacement than the surface support,which should be installed as soon as possible with a suitable length.For tunnels excavated in weak rocks or with restricted displacement control requirements,the surface support should also be installed or closed timely with a certain stiffness.The proposed method provides a convenient alternative approach for the optimization of rockbolts and surface support at the preliminary stage of tunnel design.

Influence of fault slip on mining-induced pressure and optimization ofroadway support design in fault-influenced zone

This paper presents an investigation on the characteristics of overlying strata collapse and mining-induced pressure in fault-influenced zone by employing the physical modeling in consideration of fault structure. The precursory information of fault slip during the underground mining activities is studied as well. Based on the physical modeling, the optimization of roadway support design and the field verification in fault-influenced zone are conducted. Physical modeling results show that, due to the combined effect of mining activities and fault slip, the mining-induced pressure and the extent of damaged rock masses in the fault-influenced zone are greater than those in the uninfluenced zone. The sharp increase and the succeeding stabilization of stress or steady increase in displacement can be identified as the precursory information of fault slip. Considering the larger mining-induced pressure in the fault-influenced zone, the new support design utilizing cables is proposed. The optimization of roadway support design suggests that the cables can be anchored in the stable surrounding rocks and can effectively mobilize the load bearing capacity of the stable surrounding rocks. The field observation indicates that the roadway is in good condition with the optimized roadway support design.

Prediction of Pressure Drop of Slurry Flow in Pipeline by Hybrid Support Vector Regression and Genetic Algorithm Model

这份报纸描述柔韧的支持向量回归(SVR ) 方法论，它能为重要过程工程问题提供优异性能。方法为 SVR 元参数的有效调节合并混合支持向量回归和基因算法技术(SVR-GA ) 。算法被申请了稳固的液体的压力落下的预言泥浆流动。有在文学的选择关联的比较证明发达 SVR 关联显著地在大量操作条件，物理性质，和管子直径上改进了压力落下的预言。

Upper bound solutions for supporting pressures of shallow tunnels with nonlinear failure criterion

线性失败标准广泛地在对浅隧道起作用的地球压力的计算被使用。然而，试验性的证据证明那个非线性的失败标准能表示相当，很好，几乎所有的失败岩石打字。一个非线性的 Hoek 布郎失败标准被采用在限制分析框架估计浅隧道的支持的压力。二失败机制为计算外部力量和内部精力驱散的工作率被建议。到非线性的失败标准的一根正切的线被用来作为一个非线性的编程问题提出支持的压力问题。这样提出的客观功能关于失败机制和接触点的地点被最小化。以便估计有效性，为建议失败机制的支持的压力被计算，当非线性的标准被归结为线性标准时，与对方，和礼品相比，结果与以前出版的答案相比。协议支持建议失败机制的有效性。一个实验被进行在倒塌形状和浅隧道的支持的压力上调查非线性的标准的影响。

Impact of impregnation pressure on desulfurization performance of Zn-based sorbents supported on semi-coke

High-pressure impregnation, a new preparation method for sorbents to remove H2S from hot coal gas, is introduced in this paper. Semi-coke （SC） and ZnO is selected as the support and active component of sorbent, respectively. The sorbent preparation process includes high-pressure impregnation, filtration, ovendry and calcination. The aim of this research is to primarily study the effects of the impregnation pressure on physical properties and desulfurization ability of the sorbent. The desulfurization experiment was carried out in a fixed-bed reactor at 500 ~C and a simulated coal gas used in this work was composed of CO （33 vol%）, H2 （39 vol%）, H2S （300 ppm in volume）, and N2 （balance）. Experimental results show that the pore structure of the SC support can be improved effectively and ZnO active component can be uniformly dispersed on the support, with the small particle size of 10-500 nm. Sorbents prepared using high-pressure impregnation have better desulfurization capacity and their active components have higher utilization rate. P20-ZnSC sorbent, obtained by high-pressure impregnation at 20 atm, has the best desulfurization ability with a sulfur capacity of 7.54 g S/100g sorbent and a breakthrough time of 44 h. Its desulfurization precision and efficiency of removing H2S from the middle temperature gases can reach 〈 1 ppm and 〉99.7%, respectively, before sorbent breakthrough.

Contact pressure distribution and support angle optimization of kiln tyre

According to the shearing force character and the deformation coordination condition of shell at the station of supports, the mathematical models to calculate contact angle and contact pressure distribution between tyre and shell were set up, the formulae of bending moment and bending stress of tyre were obtained. Taking the maximum of tyre fatigue life as the optimal objective, the optimization model of tyre support angle was built. The computational results show that when tyre support angle is 30°, tyre life is far less than that when tyre support angle is optimal, which is 35.6°, and it is unsuitable to stipulate tyre support angle to be 30° in traditional design. The larger the load, the less the nominal stress amplitude increment of tyre, the more favorable the tyre fatigue life when tyre support angle is optimal.

The Analysis of Performance on Spring Supported Thrust Pads Inclusive of One Dimensional Pressure Buildup

In the paper, a solution of one dimensional fore region pressure build up is put forward. The performance of spring supported thrust bearing is carried out with 3 dimensional thermo elasto hydrodynamic (TEHD) lubrication theory inclusive of inlet pressure build up, thermal elastic distortion of pad and thermal effect. The effects of fore region pressure build up and the variation of some operating conditions on the performance of the pad are studied.

Effects of ultrasound on the desulfurization performance of hot coal gas over Zn-Mn-Cu supported on semi-coke sorbent prepared by high-pressure impregnation method

Zn-Mn-Cu/SC（U） sorbent was hydrothermally synthesized by ultrasound-assisted high-pressure impregnation method with semi-coke（SC）as support and the mixed solution of zinc nitrate,manganese nitrate and copper nitrate as active component precursors.The desulfurization performances of hot coal gas on the prepared sorbent at a mid-temperature of 500°C were tested in fixed-bed reactor.Morphology and pore structure of the prepared sorbent were also characterized by TEM,N2adsorption/desorption isotherms and XRD.For comparison,the sorbent of Zn-Mn-Cu/SC prepared by conventional high-pressure impregnation was also evaluated and characterized in order to study the effects of ultrasound treatment.Zn-Mn-Cu/SC（U） sorbent prepared by high-pressure impregnation under ultrasound-assisted condition showed a better desulfurization performance than Zn-Mn-Cu/SC.It could remove H2 S from 1000×10-6m3/m3 to 0.1×10-6m3/m3 at 500°C and maintained for 12.5 h with the sulfur capacity of 7.74%,in which both the breakthrough time and sulfur capacity were about 32% and 51% higher than those of Zn-Mn-Cu/SC sorbent.The introduction of ultrasound during high-pressure impregnation process greatly improved the morphology and pore structure of the sorbent.The ultrasonic treatment made particle size of active components smaller and made them more evenly disperse on semi-coke support,which provided more opportunities to contact with H2S in coal-based gases.However,there were no any difference in compositions and existing forms of active components on the Zn-Mn-Cu/SC and Zn-Mn-Cu/SC（U） sorbents.

Finite Element Modeling of Stability of Beam-Column Supports for Field Fabricated Spherical Storage Pressure Vessels

Spherical pressure vessels in large sizes are generally supported on legs or columns evenly spaced around the circumference. The legs are attached at or near the equator of the sphere. This research work focussed on flexural-torsional buckling of beam-column supports of field fabricated spherical pressure vessels using finite element analysis. Flexuraltorsional buckling is an important limit state that must be considered in structural steel design and it occurs when a structural member experiences significant out-of-plane bending and twisting. This research has therefore considered the total potential energy equation for the flexural-torsional buckling of a beam-column element. The energy equation was formulated by summing the strain energy and the potential energy of the external loads. The finite element method was applied in conjunction with the energy method to analyze the flexural-torsional buckling of beam-column supports. To apply the finite element method, the displacement functions are assumed to be cubic polynomials, and the shape functions used to derive the element stiffness and element geometric stiffness matrices. The element stiffness and geometric stiffness matrices were assembled to obtain the global stiffness matrices of the structure. The final finite element equation obtained was in the form of an eigenvalue problem. The flexural-torsional buckling loads of the structure were determined by solving for the eigenvalue of the equation. The resulting eigenvalue equation from the finite element analysis was coded using FORTRAN 90 programming language to aid in the analysis process. To validate FORTRAN 90 coding developed for the finite element analysis and the methodology, the results given by the software were compared to existing solutions and showed no significant difference P > 0.05.

Probability Analysis of the Wave-Slamming Pressure Values of the Horizontal Deck with Elastic Support

This paper presents the probability distribution of the slamming pressure from an experimental study of regular wave slamming on an elastically supported horizontal deck. The time series of the slamming pressure during the wave impact were first obtained through statistical analyses on experimental data. The exceeding probability distribution of the maximum slamming pressure peak and distribution parameters were analyzed, and the results show that the exceeding probability distribution of the maximum slamming pressure peak accords with the three-parameter Weibull distribution. Furthermore, the range and relationships of the distribution parameters were studied. The sum of the location parameter D and the scale parameter L was approximately equal to 1.0, and the exceeding probability was more than 36.79% when the random peak was equal to the sample average during the wave impact. The variation of the distribution parameters and slamming pressure under different model conditions were comprehensively presented, and the parameter values of the Weibull distribution of wave-slamming pressure peaks were different due to different test models. The parameter values were found to decrease due to the increased stiffness of the elastic support. The damage criterion of the structure model caused by the wave impact was initially discussed, and the structure model was destroyed when the average slamming time was greater than a certain value during the duration of the wave impact. The conclusions of the experimental study were then described.

Mechanism and control technology of strong ground pressure behaviour induced by high-position hard roofs in extra-thick coal seam mining

This work aimed at revealing the mechanism of strong ground pressure behaviour(SGPB)induced by high-position hard roof(HHR).Based on the supporting structures model of HHR,a modified voussoir beam mechanical model for HHR was established by considering the gangue support coefficient,through which the modified expressions of limit breaking span and breaking energy of HHR were deduced.Combined with the relationship between the dynamic-static loading stress of supporting body(hydraulic support and coal wall)and its comprehensive supporting strength,the criteria of ground pressure behaviour(GPB)induced by HHR were discussed.The types of Ⅰ_(1),Ⅰ_(2),Ⅱ_(1),andⅡ_(2) of GPB were interpreted.Results showed that types Ⅰ_(1) and Ⅰ_(2) were the main forms of SGPB in extra-thick coal seam mining.The main manifestation of SGPB was static stress,which was mainly derived from the instability of HHR rather than fracture.Accordingly,an innovative control technology was proposed,which can weaken static load by vertical-well separated fracturing HHR.The research results have been successfully applied to the 8101 working face in Tashan coal mine,Shanxi Province,China.The results of a digital borehole camera observation and stress monitoring proved the rationality of the GPB criteria.The control technology was successful,paving the way for new possibilities to HHR control for safety mining.

Application of new void detection algorithm for analysis of feed pressure and rotation pressure of roof bolters

Roof and rib instability is an important issue in underground mining. To optimize ground support design,enhance ground stability, and reduce the possibility of roof or rib failure with minimal use of artificial ground support, it is essential to have an accurate understanding of ground conditions. This includes the location of voids, cracks, and discontinuities, as well as information about the different strata in the immediate roof. This paper briefly introduces ongoing research on void detection by using the roof bolter feed and rotation pressure. The goal of this project is to improve the sensitivity of detection programs to locate smaller joints and reduce the number of false alarms. This paper presents a brief review of the testing procedures, data analysis, logic, and algorithms used for void detection. In addition, this paper discusses the results of preliminary laboratory tests and statistical analysis of the data from these two drilling parameters used for void detection.

Non-Invasive Positive Pressure Ventilation (NIPPV) in the Pregnant Patient: A Case Series

Rationale: Acute respiratory failure is an uncommon complication of pregnancy. However, it is the most frequent organ dysfunction associated with obstetric admissions to an intensive care unit. The obstetric population is a different group due to its physiology and the presence of the fetus that lacks evidence in the literature within the subject of ventilatory support. Noninvasive positive pressure ventilation (NIPPV) is often avoided due to the lack of knowledge on the safety and efficacy of this modality. Currently, there are no guidelines for the management of respiratory failure in pregnancy. Objectives: To provide evidence in support of the use of NIPPV as a safe and reasonable modality for pregnant patients with respiratory failure. Methods: We retrospectively reviewed medical records of 29 pregnant patients of the Obstetric Critical Care Unit of a tertiary hospital in Panamá City who received NIPPV from 2013 to 2015. Failure to response was defined as the lack of increase in the paO2/FiO2 ratio or clinical deterioration 6 hours after initiating NIPPV. Demographics, indication for NIPPV, duration of treatment, as well as maternal and fetal outcomes were collected. Measurements and Main Results: Mean age was 28.4 ± 6 years, mean body mass index 27.4 ± 3.3, and mean gestational age at admission was 305/7 ± 5 weeks. Twenty-four patients (82.8%) met the criteria for acute lung injury (ALI) and an additional two (6.9%) for acute respiratory distress syndrome (ARDS). The mean duration of ventilation was 50.6 ± 17.27 hours. Statistically significant differences were noted between the paO2/FiO2 ratios in failure and successful patients within 2 hours of NIPPV therapy (P = 0.007) and paO2/FiO2 ratio within 6 hours of NIPPV therapy (P = 0.03). Success was defined when the patient was administered NIPPV, resulting in an improvement (increase in pa/FiO2 ratio) of her ventilatory parameters. Three patients (10.3%) failed to respond to NIPPV and needed to be converted to invasive mechanical ventilation. Patients who required intubation had a longer duration of ICU stay (P = 0.006) and overall hospital stay (P = 0.03). None of patients presented aspiration during NIPPV therapy. Conclusion: The current series is the largest report of pregnant patients requiring ventilatory support who received NIPPV as first line of therapy. This report shows the usefulness of this ventilation modality, avoiding intubation with its risks, of a significant number of patients, especially ventilator-associated pneumonia.

基于SVM的干线输气管道泄漏压降速率信号识别

为解决压缩机抽吸或截断阀截断形成的压降信号导致截断阀发生误关断,以及小孔泄漏因管道压降不显著导致截断阀不动作的问题,以某输气干线为对象建立仿真模型,获取压缩机抽吸、截断阀紧急截断及管道泄漏3类不同工况下的300组压降信号,根据对点检测法计算出压降信号的压降速率值;以奇异值分解(SVD)法和极差归一化方法提取压降速率信号特征,采用支持向量机(SVM)法识别不同压降速率特征值信号,获取所对应的工况类型;针对SVM模型中的核函数参数与惩罚因子设置不合理,影响算法识别准确性的问题,采用教与学优化算法(TLBO)优化核函数参数与惩罚因子,建立干线输气管道泄漏信号智能识别的TLBO-SVM模型;应用该模型,分类识别该管道在3类工况下的300组模拟压降速率信号。结果表明:该模型对3类不同工况下压降速率信号的识别准确率为92.22%;对泄漏口径为50~125 mm,压降速率范围为0.01~0.07 MPa/min的小孔泄漏,识别准确率为96.67%。针对某干线管道的实际泄漏压降速率信号,TLBO-SVM识别到的准确率为100%。

基于差分非平稳Transformer的液压支架立柱压力预测

液压支架立柱压力预测是回采工艺决策的重要依据,也是确保围岩稳定的基础信息之一。然而,液压支架立柱压力虽然具有一定的规律性,却无法用简单的数学模型进行预测;且在回采过程中,支架不接顶、顶板破碎、传感器检测误差等带来大量的随机噪声,使得压力数据劣化为非平稳时间序列,给压力的预测带来的很大的困难。本文在Transformer基础上,提出一种差分非平稳Transformer模型,在Transformer的编码器和解码器中分别引入差分归一化和反归一化操作,以提升序列的平稳性。同时,在Transformer中采用去平稳注意力机制,计算序列元素之间的关联关系,以增强模型的预测能力。在真实的煤矿支架立柱数据集上的对比实验表明,本文提出的差分非平稳Transformer的预测效果达到0.674,表现明显优于LSTM、Transformer和非平稳Transformer模型。

液压支架立柱防冲吸能构件优化仿真及压溃实验研究

液压支架作为煤炭开采主要支护设备,经常受到冲击地压影响,防冲吸能构件起到保护液压支架作用,为获得更大的初始支反力峰值与吸能量、更小的支反力分散度,对吸能构件参数细化并通过ABAQUS有限元软件进行吸能构件的建模与压溃冲击仿真,获取吸能构件的吸能性能及屈曲变形形态,验证最优尺寸的吸能性能;对比吸能构件平均支反力的预测数据与有限元仿真数据,误差在15%以内,最优尺寸构件的平均支反力模型预测误差为−3.40%,验证吸能构件预测模型所预测数据较为准确;搭建吸能构件压溃实验台,选择5种加载速度,以准静态压溃方式对定制加工的吸能构件进行轴向加载压溃实验,实验结果表明:不同加载速度轴向压溃实验,支反力波动基本一致,最大初始支反力峰值为2253.52 kN,最大支反力标准差为206.23 kN,最小初始支反力峰值为2096.26 kN,最小支反力标准差为189.83 kN,初始支反力峰值的平均值为2149.32 kN,支反力标准差平均值为196.77 kN;不同压溃速度下的轴向压溃实验数据与吸能构件有限元仿真数据对比,初始支反力峰值、支反力标准差的相对误差分别为5.6%、11.07%;对最优尺寸吸能构件通过预测模型法、有限元仿真法、压溃实验法三种方法进行吸能性能分析,预测模型法的平均支反力为1879.7 kN,有限元仿真法的平均支反力为1945.9 kN,压溃实验法平均支反力为1919.8 kN,预测模型误差3.41%,压溃实验误差−1.3%,通过3种方法的数据验证结果,证明了吸能构件分析方法的可靠性和可行性。

基于LSTM-Informer模型的液压支架压力时空多步长预测

目前多步液压支架压力预测大多为单步液压支架压力的累计预测,单步累计次数越多,累计误差就越大,影响预测精度。针对该问题,提出了一种基于长短时记忆(LSTM)-Informer模型的液压支架压力时空多步长预测方法。采用卡尔曼滤波消除液压支架压力数据中的振动噪声后,在工作面端部和中部各选取相邻的5台液压支架压力数据建立2个时空数据集(数据集1和数据集2),并对时空数据进行标准化预处理。将时空数据输入LSTM模型提取时空特征,并将提取的时空特征输入Informer模型的编码器,经过位置编码后利用多头概率稀疏自注意力来关注压力序列的变化特征,经过最大池化和一维卷积消除最终输出特征图的冗余组合。利用多头概率稀疏自注意力来关注压力序列的变化特征,将Informer模型的解码器改为全连接层,得到液压支架压力的预测结果。实验结果表明:与基于门控循环单元(GRU)、LSTM和Informer模型的预测方法相比,基于LSTM-Informer模型的预测方法在预测6,12,24步长液压支架压力时的均方根误差(RMSE)和平均绝对误差(MAE)均最小;其中基于数据集1预测的6步长液压支架压力的RMSE分别降低了41.63%,49.74%,11.85%,MAE分别降低了41.75%,50.00%,12.00%;基于数据集2预测的6步长液压支架压力的RMSE分别降低了48.15%,59.86%,19.88%,MAE分别降低了49.87%,54.90%,13.16%。