The stamping-out strategy has been used to control highly pathogenic avian influenza viruses in many countries,driven by the belief that vaccination would not be successful against such viruses and fears that avian in...The stamping-out strategy has been used to control highly pathogenic avian influenza viruses in many countries,driven by the belief that vaccination would not be successful against such viruses and fears that avian influenza virus in vaccinated birds would evolve more rapidly and pose a greater risk to humans.In this review,we summarize the successes in controlling highly pathogenic avian influenza in China and make suggestions regarding the requirements for vaccine selection and effectiveness.In addition,we present evidence that vaccination of poultry not only eliminates human infection with avian influenza virus,but also significantly reduces and abolishes some harmful characteristics of avian influenza virus.展开更多
This paper introduced the characteristics of avian leukosis from the aspects of pathogen,epidemiology,clinical symptoms,and anatomical symptoms,and puts forward clinical comprehensive diagnosis and laboratory diagnost...This paper introduced the characteristics of avian leukosis from the aspects of pathogen,epidemiology,clinical symptoms,and anatomical symptoms,and puts forward clinical comprehensive diagnosis and laboratory diagnostic methods.Besides,the disease is also differentiated from similar diseases of chicken such as Marek's disease,infectious bursal disease and reticuloendothelial hyperplasia.Finally,the prevention and control measures against the disease were proposed.展开更多
This article introduced the vision building concept about human influenza pandemic prevention and control.Different visions were built by creating different shapes of building blocks which also represented different o...This article introduced the vision building concept about human influenza pandemic prevention and control.Different visions were built by creating different shapes of building blocks which also represented different organizations and physical facilities,respectively.The around-view reflection is required to be developed in the process of building so as to search for the ideal pattern.The correlation of all sectors and systems are established to combine different kinds of things,from one family to another,from communities,towns,counties,cities,rural areas, provinces to the state to handle trivial problems.These training objectives have been successfully accomplished,which has not only enriched the knowledge about prevention and control of influenza pandemic between different departments but also clarified the roles and responsibility. It lays the firm foundation for next cooperation between different departments,and make a bridge for the objective and choice of channel over human influenza pandemic prevention and control.展开更多
The present study showed that avian influenza virus (AIV) occurred in the regions with rice and wheat productions under low ultraviolet (UV) radiation while there were negligible AIV outbreaks in the regions with a hi...The present study showed that avian influenza virus (AIV) occurred in the regions with rice and wheat productions under low ultraviolet (UV) radiation while there were negligible AIV outbreaks in the regions with a high rate of skin cancer due to extensive UV radiation. It is therefore proposed that having artificial UV radiation with poultry farmhouses is a simple solution to suppress AIV outbreaks. AIV outbreaks can be predicted a few months in advance by remote sensing satellite parameters such as Cosmos (minimum sunspot number, 10.7 cm solar flux, high UV radiation), Poles (CO2, O3 hole deterioration, hydroxyl layer temperature, ice-melting, chlorophyll or algae, krill, penguin, guillemot), and Continents (migratory birds, desert dust, low UV radiation, waters, fish, rice and wheat, climate). Since there was an abrupt 2% rise of global CO2 emissions in 2017, while the minimum sunspot number is simultaneously reached at the end of 2018, there can be an extensive UV radiation for mutant AIV in the Poles to have the highest degree of damage by AIV in regions such as U.S., East Asia, China, South Korea, Japan, west Africa, and Europe from November of 2018 till April of 2019.展开更多
Avian influenza(AI)is one of the most relevant viruses in the poultry industry.The AI virus(AIV)transmission from birds to human causing severe cases and mortality enhanced the magnitude of AI for public health.Conseq...Avian influenza(AI)is one of the most relevant viruses in the poultry industry.The AI virus(AIV)transmission from birds to human causing severe cases and mortality enhanced the magnitude of AI for public health.Consequently,the AIV diagnosis laboratories should be able to detect and identify endemic,epidemic and seasonal influenza strains and other wildlife influenza subtypes that cross the country’s borders.The development in quality controls in according with international rules comes to improve the performance of tests.With this purpose,the Brazilian Reference Laboratory for Avian Influenza(LANAGRO-SP)established a cooperation with the World Organization for Animal Health(OIE)to produce AIV master seeds,inactivated antigens and antiserum to attend the necessities of Brazil and other South America countries under the high quality control for all test.Seventeen of AIV master seed lots and seventeen of inactivated antigens lots produced reached hemagglutination(HA)titers of 1:512 and 1:256,respectively.In addition,fifteen AIV antiserum lots with hemagglutination inhibition(HI)titers reaching 1:4,096 were obtained.The AIV reference reagents produced and applied in laboratory routine successfully.展开更多
The highly pathogenic avian influenza H5N1 pandemic motivated countries around the World to be prepared for outbreaks within their borders. Well ahead of the outbreak, in Jordan contingency plans were prepared involvi...The highly pathogenic avian influenza H5N1 pandemic motivated countries around the World to be prepared for outbreaks within their borders. Well ahead of the outbreak, in Jordan contingency plans were prepared involving all relevant bodies in both the private and public sectors and a practice was simulated to test the effectiveness of the task force and the applicability of the plan. The highly pathogenic H5N1 influenza virus was detected and confirmed in one turkey in a backyard flock comprising 12 turkeys and 25 chickens in Kufranjah, 6 km from Ajloun city, on 23 March 2006. The samples were confirmed by the following day. Control measures were implemented immediately according to the national contingency plan and complete clean up achieved by 27 March 2006. A 3 km area around the index case was designated as a control zone, with a 10 km area around the holding further designated as a surveillance zone. The objective was to stamp out the infection and approximately 20,000 birds were destroyed including all commercial and backyard flocks in the control zone. All the human contacts were examined, treated and discharged from the hospital. The immediate response from all Jordanian sectors involved in the control strategy was positive as a result of increasing awareness and training programs that were implemented six months before the occurrence of the outbreak. A total estimated economic loss posed by this outbreak including compensation was almost $US169 million. Following the outbreak, passive surveil-lance for the virus was undertaken and training and capacity building continued. Efforts made in the preparation for an outbreak paid dividends and the need for a department responsible for monitoring migratory and wild birds in Jordan was recognized. Legislation regarding biosecurity of poultry farms and poultry transport vehicles should be revised.展开更多
基金This work was supported by the National Key Research andDevelopment Programof China(2021YFD1800200 and2021YFC2301700).
文摘The stamping-out strategy has been used to control highly pathogenic avian influenza viruses in many countries,driven by the belief that vaccination would not be successful against such viruses and fears that avian influenza virus in vaccinated birds would evolve more rapidly and pose a greater risk to humans.In this review,we summarize the successes in controlling highly pathogenic avian influenza in China and make suggestions regarding the requirements for vaccine selection and effectiveness.In addition,we present evidence that vaccination of poultry not only eliminates human infection with avian influenza virus,but also significantly reduces and abolishes some harmful characteristics of avian influenza virus.
基金Supported by Anhui Province Key Research and Development Plan(202204c06020039)Hefei Comprehensive Experimental Station of National Egg Chicken Industry Technology System(CARS-40-S10)+1 种基金Anhui Province Poultry Industry Technology System(AHCYJSTX-06)Anhui Academy of Agricultural Sciences Platform Project(2023YL013).
文摘This paper introduced the characteristics of avian leukosis from the aspects of pathogen,epidemiology,clinical symptoms,and anatomical symptoms,and puts forward clinical comprehensive diagnosis and laboratory diagnostic methods.Besides,the disease is also differentiated from similar diseases of chicken such as Marek's disease,infectious bursal disease and reticuloendothelial hyperplasia.Finally,the prevention and control measures against the disease were proposed.
基金supported by a grant form by the World Bank(FIo-016) for China capacity building for highly pathogenic avian influenza prevention and human pandemic influenza preparedness projectgranted by Australia, European Union,and other donor countries
文摘This article introduced the vision building concept about human influenza pandemic prevention and control.Different visions were built by creating different shapes of building blocks which also represented different organizations and physical facilities,respectively.The around-view reflection is required to be developed in the process of building so as to search for the ideal pattern.The correlation of all sectors and systems are established to combine different kinds of things,from one family to another,from communities,towns,counties,cities,rural areas, provinces to the state to handle trivial problems.These training objectives have been successfully accomplished,which has not only enriched the knowledge about prevention and control of influenza pandemic between different departments but also clarified the roles and responsibility. It lays the firm foundation for next cooperation between different departments,and make a bridge for the objective and choice of channel over human influenza pandemic prevention and control.
文摘The present study showed that avian influenza virus (AIV) occurred in the regions with rice and wheat productions under low ultraviolet (UV) radiation while there were negligible AIV outbreaks in the regions with a high rate of skin cancer due to extensive UV radiation. It is therefore proposed that having artificial UV radiation with poultry farmhouses is a simple solution to suppress AIV outbreaks. AIV outbreaks can be predicted a few months in advance by remote sensing satellite parameters such as Cosmos (minimum sunspot number, 10.7 cm solar flux, high UV radiation), Poles (CO2, O3 hole deterioration, hydroxyl layer temperature, ice-melting, chlorophyll or algae, krill, penguin, guillemot), and Continents (migratory birds, desert dust, low UV radiation, waters, fish, rice and wheat, climate). Since there was an abrupt 2% rise of global CO2 emissions in 2017, while the minimum sunspot number is simultaneously reached at the end of 2018, there can be an extensive UV radiation for mutant AIV in the Poles to have the highest degree of damage by AIV in regions such as U.S., East Asia, China, South Korea, Japan, west Africa, and Europe from November of 2018 till April of 2019.
文摘Avian influenza(AI)is one of the most relevant viruses in the poultry industry.The AI virus(AIV)transmission from birds to human causing severe cases and mortality enhanced the magnitude of AI for public health.Consequently,the AIV diagnosis laboratories should be able to detect and identify endemic,epidemic and seasonal influenza strains and other wildlife influenza subtypes that cross the country’s borders.The development in quality controls in according with international rules comes to improve the performance of tests.With this purpose,the Brazilian Reference Laboratory for Avian Influenza(LANAGRO-SP)established a cooperation with the World Organization for Animal Health(OIE)to produce AIV master seeds,inactivated antigens and antiserum to attend the necessities of Brazil and other South America countries under the high quality control for all test.Seventeen of AIV master seed lots and seventeen of inactivated antigens lots produced reached hemagglutination(HA)titers of 1:512 and 1:256,respectively.In addition,fifteen AIV antiserum lots with hemagglutination inhibition(HI)titers reaching 1:4,096 were obtained.The AIV reference reagents produced and applied in laboratory routine successfully.
文摘The highly pathogenic avian influenza H5N1 pandemic motivated countries around the World to be prepared for outbreaks within their borders. Well ahead of the outbreak, in Jordan contingency plans were prepared involving all relevant bodies in both the private and public sectors and a practice was simulated to test the effectiveness of the task force and the applicability of the plan. The highly pathogenic H5N1 influenza virus was detected and confirmed in one turkey in a backyard flock comprising 12 turkeys and 25 chickens in Kufranjah, 6 km from Ajloun city, on 23 March 2006. The samples were confirmed by the following day. Control measures were implemented immediately according to the national contingency plan and complete clean up achieved by 27 March 2006. A 3 km area around the index case was designated as a control zone, with a 10 km area around the holding further designated as a surveillance zone. The objective was to stamp out the infection and approximately 20,000 birds were destroyed including all commercial and backyard flocks in the control zone. All the human contacts were examined, treated and discharged from the hospital. The immediate response from all Jordanian sectors involved in the control strategy was positive as a result of increasing awareness and training programs that were implemented six months before the occurrence of the outbreak. A total estimated economic loss posed by this outbreak including compensation was almost $US169 million. Following the outbreak, passive surveil-lance for the virus was undertaken and training and capacity building continued. Efforts made in the preparation for an outbreak paid dividends and the need for a department responsible for monitoring migratory and wild birds in Jordan was recognized. Legislation regarding biosecurity of poultry farms and poultry transport vehicles should be revised.
