As proposed in the UNAIDSs 2014 report,to end global AIDS epidemic by 2030,90%of people living with HIV need to be diagnosed,90%of the diagnosed need to receive antiretroviral therapy(ART),and 90%of those on treatment...As proposed in the UNAIDSs 2014 report,to end global AIDS epidemic by 2030,90%of people living with HIV need to be diagnosed,90%of the diagnosed need to receive antiretroviral therapy(ART),and 90%of those on treatment need to achieve viral suppression(90-90-90 strategy).The strategies focus on the reservoir.It controls HIV spreading by reducing infectiousness of HIV infected individuals via diagnosis and treatment.In this manuscript,we compared the effects of HIV/AIDS interventions that focus on different individuals in MSM population through a dynamics model.Our results showed that,the success or not of the”90-90-90”strategies depends on a very important factor:the infectious strength among individuals taking ART.Without highly effective HIV treatment,the”90-90-90”strategies are likely to fail.Therefore,we call for the combination of both primary prevention among the susceptible with the 90-90-90 strategy among the infected to curb the HIV epidemic in Chinese MSM.展开更多
基金This study was supported by the Natural Science Foundation of China(No.11771277 and No.11331009)the Guangxi Science and Technology Bureau(Grant AB16380213)Guangxi Bagui Honor Scholarship,and Chinese State Key Laboratory of Infectious Disease Prevention and Control。
文摘As proposed in the UNAIDSs 2014 report,to end global AIDS epidemic by 2030,90%of people living with HIV need to be diagnosed,90%of the diagnosed need to receive antiretroviral therapy(ART),and 90%of those on treatment need to achieve viral suppression(90-90-90 strategy).The strategies focus on the reservoir.It controls HIV spreading by reducing infectiousness of HIV infected individuals via diagnosis and treatment.In this manuscript,we compared the effects of HIV/AIDS interventions that focus on different individuals in MSM population through a dynamics model.Our results showed that,the success or not of the”90-90-90”strategies depends on a very important factor:the infectious strength among individuals taking ART.Without highly effective HIV treatment,the”90-90-90”strategies are likely to fail.Therefore,we call for the combination of both primary prevention among the susceptible with the 90-90-90 strategy among the infected to curb the HIV epidemic in Chinese MSM.
