Marginal zone lymphoma with severe rashes: A case report

BACKGROUND Marginal zone lymphoma(MZL)is an indolent subtype of non-Hodgkin lymphoma(NHL),which is rare clinically with severe rashes as the initial symptom.CASE SUMMARY This study reports a case of MZL with generalized skin rashes accompanied by pruritus and purulent discharge.First-line treatment with rituximab combined with zanubrutinib had poor effects.However,after switching to obinutuzumab combined with zanubrutinib,the case was alleviated,and the rashes disappeared.CONCLUSION For patients with advanced stage MZL not benefiting from type I anti-CD20 monoclonal antibody(mAb)combination therapy,switching to a type II anti-CD20 mAb combination regimen may be considered.This approach may provide a new perspective in the treatment of MZL.

Study on Landscape Pattern Index-based Connectivity Analysis of the Primary Farmland Protection Zones

Farmland and primary farmland protection are important contents of land management and land use planning of China. In the new round of land use planning and database construction, primary farmland protection zones are required to have high integrity and connectivity. Using landscape pattern indexes, the integrity and connectivity of primary farmland protection zones was studied in Licheng District of Jinan City. The results showed that, except patch area standard deviation, the other indexes including average patch area, patch area variation coefficient, patch edge density, largest patch index, and mean euclidean nearest-neighbor, all indicate high connectivity of primary farmland protection zones after layout adjustment. A simple and convenient method for identifying the integrity and connectivity of primary farmland protection zones was supplied.

The Dynamic Mechanisms for the Formation of Primary Metal Zoning of Cassiterite-Sulfide Deposits in the Gejiu Metallogenic Province, Yunnan

Copper and tin in cassiterite-sulfide deposits of the Gejiu metallogenic province are intimately associatedand show peculiar primary metal zoning. The authors made use of computer techniques to simulatenumerically the zoning of these ore deposits. The study shows that the regular spatial zoning probably resultedfrom the succession of multiple, intermittent and pulsatory mineralizations, The successive transports with di-verse velocities along channelways of the ore-forming solutions, taking place under conditions of definite dif-ference between metal concentrations, in solutions and wallrocks, followed by differential deposition, consti-tute possible dynamic mechanisms for the primary metal zoning.

PIV MEASUREMENT FOR SWIRLER FLOW FIELD IN GAS TURBINE COMBUSTOR

The characteristics of swirler flow field, including cold flow field and combustion flow field, in gas tur- bine combustor with two-stage swirler are studied by using particle image velocimetry （PIV）. Velocity compo- nents, fluctuation velocity, Reynolds stress and recirculation zone length are obtained, respectively. Influences of geometric parameter of primary hole, arrangement of primary hole, inlet air temperature, first-stage swirler an- gle and fuel/air ratio on flow field are investigated, respectively. The experimental results reveal that the primary recirculation zone lengths of combustion flow field are shorter than those of cold flow field, and the primary reeir- culation zone lengths decrease with the increase of inlet air temperature and fuel/air ratio. The change of the geo- metric parameter of primary hole casts an important influence on the swirler flow field in two-stage swirler com- bustor.

Analysis on Lean Blowout of Swirl Cup Combustor at Atmospheric Pressure Condition

The experimental data of lean blowout fuel/air ratio of a rectangular swirl cup combustor with different inlet temperatures was obtained at atmospheric pressure condition.Numerical simulations both burning and non-burning were performed corresponding to the experimental data at lean blowout.Results indicated that the size of the recirculation region in the primary zone was obviously smaller when burning than non-burning,but the locations of the cores of their recirculation regions were almost the same.The increase of inlet air temperature didn't mean the rise of the temperature of recirculation region core.The location of the maximum temperature in the primary zone was not the same as that one of the core temperature of the recirculation region.Further more,the reasons were analyzed how the lean blowout fuel/air ratio changed with the inlet temperature increasing under the actions of factors both positive and negative to combustion,and this would be helpful to deepen the understanding of the lean blowout process of swirl cup combustor.

A Study on Lean Blowout of Multi-vortexes-dome Model Combustor

The lean blowout experiments of the combustion stability device A (multi-vortexes-dome model combustor) have been carried out at atmospheric pressure. Compared with the device B (single-vortex-dome model combustor), the experimental results show that the device A has a superior lean blowout performance when the combustor reference velocity is within the range from 3.50m/s to 5.59m/s ( while the liner reference velocity is between 3.84 and 6.13m/s), and this superiority will remain stable after the inlet air flow rate reaches a certain value. In order to analyze the phenomena and experimental results, the numerical simulation method is used, and the strain rate and the cold reflux impact are employed to further explain the reason that causes the difference between the two devices' lean blowout characteristics.