To research the hair-care efficacy of prinsepia utilis oil.We evaluated the haircare efficacies of prinsepia utilis oil through methods such as differential scanning calorimetry(DSC),measuring difficulty level and mec...To research the hair-care efficacy of prinsepia utilis oil.We evaluated the haircare efficacies of prinsepia utilis oil through methods such as differential scanning calorimetry(DSC),measuring difficulty level and mechanical resistance against combing of wet and dry hair,scanning electron microscopy(SEM).According to the analysis of differential scanning calorimetry(DSC),the testing sample has repairing effect on the hairα-keratin damage induced by heated blowing.According to the pictures of scanning electron microscopy(SEM),The test results indicate the repairing or resisting thermal damage effects induced by hair drier of prinsepia utilis oil.By comparison with the blank control group,the strength and work of dry comb and wet comb were significantly reduced in the samples tested with 2%prinsepia utilis oil concentration(P﹤0.05).This indicates the testing sample has the efficacy to improve the easiness of combing and anti-tangle.And friction work is significantly reduced This indicates the smoothing efficacy of the testing sample.and the hair scales status is better;this indicates hair scales repairing efficacy of testing sample.Conclusion:PRINSEPIA UTILIS OIL has the effect of repairing hair scales,resisting thermal damage caused by hair dryer,easy to comb,anti-tangle,smoothing.展开更多
A new hemiterpenoid, （＋）-（2R,3S）-2-chloro-3-hydroxy-3-methyl-T-buty-rolactone was isolatexi from the leaves of Prinsepia utilis Royle. Its structure was clucidatexi by spectroscopic methods and X-ray crystallogra...A new hemiterpenoid, （＋）-（2R,3S）-2-chloro-3-hydroxy-3-methyl-T-buty-rolactone was isolatexi from the leaves of Prinsepia utilis Royle. Its structure was clucidatexi by spectroscopic methods and X-ray crystallographic analysis.展开更多
The purpose of this study is to isolate the active fraction from the crude extract of Prinsepia utilis Royle and to determine its antibacterial activity against the standard and drug-resistant bacteria strains in vitr...The purpose of this study is to isolate the active fraction from the crude extract of Prinsepia utilis Royle and to determine its antibacterial activity against the standard and drug-resistant bacteria strains in vitro. The Prinsepia utilis Royle was extracted in three portions by using petroleum ether, ethanol and water by the continuation recirculate extraction. The antibacterial activity of the extracts were evaluated by the determination of Minimum Inhibitory Concentration （MIC） and Minimum Bactericidal Concentration （MBC） values. The results showed that the ethanol extract and aqueous extract of petroleum ether showed the weakest inhibition. MIC values of the aqueous Prinsepia utilis Royle were found that they had significant effects against bacteria, while ethanol extracts against three standard bacteria （S. aureus ATCC25923, E. coli 44102, Salmonella 50041） were 25, 25, 50 mg·mL^-1 and 50, 100, 100 mg·mL^-1, MIC values of three drug-resistant bacteria （S. aureus GL17, E. coli EYAC08-56, Salmonella STQD2G.） were 50, 50, 50 mg·mL^-1 and 100, 100, 200 mg·mL^-1, respectively. MBC values of two extracts against three standard strains were 25, 50, 100mg·mL^-1 and 50, 100, 200 mg·mL^-1, MBC values of three drug-resistant bacteria were 100, 100, 100mg·mL^-1 and 200, 200, 200 mg·mL^-1, respectively.展开更多
Seven fractions were isolated from the ethyl acetate extract of Prinsepia utilis Royle by silica gel column chromatography. The antibacterial activities determined by disc diffusion method in vitro, indicated that the...Seven fractions were isolated from the ethyl acetate extract of Prinsepia utilis Royle by silica gel column chromatography. The antibacterial activities determined by disc diffusion method in vitro, indicated that the first and fourth fractions showed better antibacterial activity than the other fractions, while the sixth and seventh fractions did not showed any antibacterial activity. The diameters of the inhibition zone of first and fourth fractions were greater than 10 mm against three standard strains (Staphylococcus aureus ATCC25923, Escherichia coli ATCC44102 and Salmonella sp. CMCC(B)50041) at the concentration of 20 mg/ml. The first fraction was then repeatedly recrystallized in acetone to yield a white snowflake-like compound A, the inhibition zones of which were 14.03 mm, 11.54 mm and 12 mm, respectively. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were measured by broth dilution method at the concentrations ranging from 20 to 0.313 mg/mL. The MIC and MBC values of the first, fourth fractions and compound A were lower than that of oregano oil (positive control) against S. aureus ATCC25923.展开更多
目的:评价综合疗法(联合盐酸米诺环素、宽谱强脉冲光和含青刺果油屏障修复霜)治疗玫瑰痤疮的临床有效性和安全性。方法:回顾性分析2021年1月-2021年6月就诊于上海交通大学医学院附属第九人民医院皮肤科门诊,主要表现为红斑、丘疹和毛细...目的:评价综合疗法(联合盐酸米诺环素、宽谱强脉冲光和含青刺果油屏障修复霜)治疗玫瑰痤疮的临床有效性和安全性。方法:回顾性分析2021年1月-2021年6月就诊于上海交通大学医学院附属第九人民医院皮肤科门诊,主要表现为红斑、丘疹和毛细血管扩张的玫瑰痤疮患者20例。给予患者口服盐酸米诺环素50 mg,2次/日,连续4周;联合宽谱强脉冲光(Broad band light,BBL)治疗,1次/月,共3次;同时给予患者含青刺果油皮肤屏障修复剂进行日常护肤。治疗3个月后随访1个月,评估治疗有效性和安全性。结果:治疗后,患者治疗有效率为95%,持久性红斑、毛细血管扩张、丘疹和脓疱的治疗评均分较治疗前明显降低(P<0.05)。所有患者治疗期间均未出现严重不良反应。结论:针对以持久性红斑、毛细血管扩张、丘疹和脓疱为主要表现的玫瑰痤疮,盐酸米诺环素、BBL联合含青刺果油屏障修复霜的综合疗法安全有效。展开更多
目的:探究果酸换肤联合外用主含马齿苋提取物和青刺果油护肤品治疗轻、中度寻常痤疮的临床疗效。方法:将轻、中度寻常痤疮患者随机分为对照组(果酸换肤治疗)、观察组(果酸换肤治疗联合外用主含马齿苋提取物和青刺果油护肤品),每组60例...目的:探究果酸换肤联合外用主含马齿苋提取物和青刺果油护肤品治疗轻、中度寻常痤疮的临床疗效。方法:将轻、中度寻常痤疮患者随机分为对照组(果酸换肤治疗)、观察组(果酸换肤治疗联合外用主含马齿苋提取物和青刺果油护肤品),每组60例。比较两组患者临床疗效、角质层含水量和经表皮水分流失量(Transepidermal water loss,TEWL)。结果:治疗12周后,观察组总有效率为93.33%高于对照组总有效率78.33%(P<0.05)。治疗6周、12周后观察组患者的角质含水量均高于对照组(P<0.05),且与治疗前相比,治疗6周、12周后,观察组患者的角质含水量均升高(P<0.05)。治疗6周、12周后,观察组患者的TEWL均低于对照组(P<0.05);与治疗前相比,观察组在治疗6周、12周后TEWL均降低(P<0.05)。结论:果酸换肤联合主含马齿苋提取物和青刺果油护肤品治疗面部轻、中度寻常痤疮疗效显著,同时可增加皮肤含水量,降低经表皮水分流失量,使用安全感良好。展开更多
文摘To research the hair-care efficacy of prinsepia utilis oil.We evaluated the haircare efficacies of prinsepia utilis oil through methods such as differential scanning calorimetry(DSC),measuring difficulty level and mechanical resistance against combing of wet and dry hair,scanning electron microscopy(SEM).According to the analysis of differential scanning calorimetry(DSC),the testing sample has repairing effect on the hairα-keratin damage induced by heated blowing.According to the pictures of scanning electron microscopy(SEM),The test results indicate the repairing or resisting thermal damage effects induced by hair drier of prinsepia utilis oil.By comparison with the blank control group,the strength and work of dry comb and wet comb were significantly reduced in the samples tested with 2%prinsepia utilis oil concentration(P﹤0.05).This indicates the testing sample has the efficacy to improve the easiness of combing and anti-tangle.And friction work is significantly reduced This indicates the smoothing efficacy of the testing sample.and the hair scales status is better;this indicates hair scales repairing efficacy of testing sample.Conclusion:PRINSEPIA UTILIS OIL has the effect of repairing hair scales,resisting thermal damage caused by hair dryer,easy to comb,anti-tangle,smoothing.
文摘A new hemiterpenoid, （＋）-（2R,3S）-2-chloro-3-hydroxy-3-methyl-T-buty-rolactone was isolatexi from the leaves of Prinsepia utilis Royle. Its structure was clucidatexi by spectroscopic methods and X-ray crystallographic analysis.
基金Supported by Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT0848)
文摘The purpose of this study is to isolate the active fraction from the crude extract of Prinsepia utilis Royle and to determine its antibacterial activity against the standard and drug-resistant bacteria strains in vitro. The Prinsepia utilis Royle was extracted in three portions by using petroleum ether, ethanol and water by the continuation recirculate extraction. The antibacterial activity of the extracts were evaluated by the determination of Minimum Inhibitory Concentration （MIC） and Minimum Bactericidal Concentration （MBC） values. The results showed that the ethanol extract and aqueous extract of petroleum ether showed the weakest inhibition. MIC values of the aqueous Prinsepia utilis Royle were found that they had significant effects against bacteria, while ethanol extracts against three standard bacteria （S. aureus ATCC25923, E. coli 44102, Salmonella 50041） were 25, 25, 50 mg·mL^-1 and 50, 100, 100 mg·mL^-1, MIC values of three drug-resistant bacteria （S. aureus GL17, E. coli EYAC08-56, Salmonella STQD2G.） were 50, 50, 50 mg·mL^-1 and 100, 100, 200 mg·mL^-1, respectively. MBC values of two extracts against three standard strains were 25, 50, 100mg·mL^-1 and 50, 100, 200 mg·mL^-1, MBC values of three drug-resistant bacteria were 100, 100, 100mg·mL^-1 and 200, 200, 200 mg·mL^-1, respectively.
文摘Seven fractions were isolated from the ethyl acetate extract of Prinsepia utilis Royle by silica gel column chromatography. The antibacterial activities determined by disc diffusion method in vitro, indicated that the first and fourth fractions showed better antibacterial activity than the other fractions, while the sixth and seventh fractions did not showed any antibacterial activity. The diameters of the inhibition zone of first and fourth fractions were greater than 10 mm against three standard strains (Staphylococcus aureus ATCC25923, Escherichia coli ATCC44102 and Salmonella sp. CMCC(B)50041) at the concentration of 20 mg/ml. The first fraction was then repeatedly recrystallized in acetone to yield a white snowflake-like compound A, the inhibition zones of which were 14.03 mm, 11.54 mm and 12 mm, respectively. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were measured by broth dilution method at the concentrations ranging from 20 to 0.313 mg/mL. The MIC and MBC values of the first, fourth fractions and compound A were lower than that of oregano oil (positive control) against S. aureus ATCC25923.
文摘目的:评价综合疗法(联合盐酸米诺环素、宽谱强脉冲光和含青刺果油屏障修复霜)治疗玫瑰痤疮的临床有效性和安全性。方法:回顾性分析2021年1月-2021年6月就诊于上海交通大学医学院附属第九人民医院皮肤科门诊,主要表现为红斑、丘疹和毛细血管扩张的玫瑰痤疮患者20例。给予患者口服盐酸米诺环素50 mg,2次/日,连续4周;联合宽谱强脉冲光(Broad band light,BBL)治疗,1次/月,共3次;同时给予患者含青刺果油皮肤屏障修复剂进行日常护肤。治疗3个月后随访1个月,评估治疗有效性和安全性。结果:治疗后,患者治疗有效率为95%,持久性红斑、毛细血管扩张、丘疹和脓疱的治疗评均分较治疗前明显降低(P<0.05)。所有患者治疗期间均未出现严重不良反应。结论:针对以持久性红斑、毛细血管扩张、丘疹和脓疱为主要表现的玫瑰痤疮,盐酸米诺环素、BBL联合含青刺果油屏障修复霜的综合疗法安全有效。
文摘目的:探究果酸换肤联合外用主含马齿苋提取物和青刺果油护肤品治疗轻、中度寻常痤疮的临床疗效。方法:将轻、中度寻常痤疮患者随机分为对照组(果酸换肤治疗)、观察组(果酸换肤治疗联合外用主含马齿苋提取物和青刺果油护肤品),每组60例。比较两组患者临床疗效、角质层含水量和经表皮水分流失量(Transepidermal water loss,TEWL)。结果:治疗12周后,观察组总有效率为93.33%高于对照组总有效率78.33%(P<0.05)。治疗6周、12周后观察组患者的角质含水量均高于对照组(P<0.05),且与治疗前相比,治疗6周、12周后,观察组患者的角质含水量均升高(P<0.05)。治疗6周、12周后,观察组患者的TEWL均低于对照组(P<0.05);与治疗前相比,观察组在治疗6周、12周后TEWL均降低(P<0.05)。结论:果酸换肤联合主含马齿苋提取物和青刺果油护肤品治疗面部轻、中度寻常痤疮疗效显著,同时可增加皮肤含水量,降低经表皮水分流失量,使用安全感良好。
