Survivals after liver transplantation for hepatocellular carcinoma:Granular data for a better allocation process?

To the Editor:A large international study has been recently published focusing on the combination of morphological aspects and alpha-fetoprotein(AFP)as predictors of survival in patients with hepatocellular cancer(HCC)treated with liver transplantation(LT)[1].As a matter of fact,morphology and biology represent the two sides of the same

Self-Adaptive Topic Model： A Solution to the Problem of ＂Rich Topics Get Richer＂

The problem of "rich topics get richer"(RTGR) is popular to the topic models,which will bring the wrong topic distribution if the distributing process has not been intervened.In standard LDA(Latent Dirichlet Allocation) model,each word in all the documents has the same statistical ability.In fact,the words have different impact towards different topics.Under the guidance of this thought,we extend ILDA(Infinite LDA) by considering the bias role of words to divide the topics.We propose a self-adaptive topic model to overcome the RTGR problem specifically.The model proposed in this paper is adapted to three questions:(1) the topic number is changeable with the collection of the documents,which is suitable for the dynamic data;(2) the words have discriminating attributes to topic distribution;(3) a selfadaptive method is used to realize the automatic re-sampling.To verify our model,we design a topic evolution analysis system which can realize the following functions:the topic classification in each cycle,the topic correlation in the adjacent cycles and the strength calculation of the sub topics in the order.The experiment both on NIPS corpus and our self-built news collections showed that the system could meet the given demand,the result was feasible.

Development of Future Generations:Oriented Virtual Negotiation Support System for Intergenerational Conflict

Intergenerational conflict coordination is the fundamental requirement and core of sustainable development. In this paper, through the analysis of the future generations-oriented management mechanisms for intergenerational conflict, the idea of mechanisms and institution building for the coordination and management of intergenerational conflict is put forward. Furthermore, the future generations-oriented virtual negotiation support system (NSS) for intergenerational conflict is developed, built on the analysis of the process simulation of intergenerational wealth transfer, intergenerational equilibrium allocation of resources, and strategies for the mitigation and avoidance of intergenerational conflict, through the application of advanced IT technology. The virtual NSS for intergenerational conflict is helpful to the practical application of the sustainable development theory; on the other hand, it can be applied directly to the intergenerational equilibrium allocation of resources, national economic accounting, formulation of sustainable development strategies and other urgent national economic and social development issues. Finally, the sustainable development theory can be enriched and extended. Therefore, the development of the future generations-oriented virtual NSS for intergenerational conflict has certain theoretical and practical effects on the theory of sustainable development.