Tracking the Process of Domino Ring-Opening and Coupling of Fused Imidazole and Direct Observation of Peroxide Intermediates

Comprehensive Summary,A domino ring-opening and coupling of imidazolyl annulated heterocycles 1(1a:4-methyl-1-(1-methyl-1H-benzo[d]imidazol-2-yl)-4H-benzo[d]imidazo[1,5-a]imidazole,1b:1-(1,5-dimethyl-1H-benzo[d]imidazol-2-yl)-4,7-dimethyl-4H-benzo[d]imidazo[1,5-a]imidazole)with dioxygen was developed at solvothermal condition,leading to conjugated 1,2-diamidoalkenes derivatives 2((E)-ArCONHArC=CArNHCOAr(Ar:1-methyl-1H-benzo[d]imidazolyl(2a),1,5-dimethyl-1H-benzo[d]imidazolyl(2b)))as single crystals directly.The reaction process was tracked by electrospray ionization mass spectrometry(ESI-HRMS)and a series of reaction intermediates are detected.^(18)O_(2) labeling experiment verified the source of oxygen in 2.Combining evidence from control experiments,nuclear magnetic resonance(NMR)tracking,and crystallography,a seven-step reaction pathway involving oxygen addition,ring opening,Friedel-Crafts alkylation,oxidation,and dehydration was proposed and further supported by DFT calculation.

Monitoring Computer Numerical Control Machining Progress Based on Information Fusion

To cope with the market demand dynamically,enterprise needs to obtain the production status of work in process real-timely,but the information of machining progress has feature of uncertainty and can not reflect the status of production field effectively.In this work,to overcome the ineffectiveness of computer numerical control(CNC) machining progress information extraction and its application restriction in practice because of heterogeneous system of CNC machine,based on information fusion by analyzing multi-sources information,estimating CNC machining status and predicting the machining progress through tracking tool coordinates,a CNC machining progress monitoring method is presented.The multi-sources heterogeneous information includes machining path,real-time spindle power information,manual input data and tool position.On the method of obtaining this multi-sources heterogeneous information,the method which helps explore numerical control(NC) program,monitor spindle power of CNC,collect human-computer interaction(HCI) information,obtain real-time tool coordinates and express the knowledge concerned in this field is analyzed; The decision rule of CNC machining status in the way of fusing multi-sources information in manufacturing process is summarized,as well as the machining progress tracking method in accordance with real-time tool coordinates and machining path is presented.Finally,the method discussed is proved feasible by the verification of machining progress tracking through simulation experiment.The proposed research realizes the effective integration of CNC machining progress information,and enables enterprises an efficient way to share CNC information and configure CNC resources optimally.