Inference of General Mass Action-Based State Equations for Oscillatory Biochemical Reaction Systems Using <i>k</i>-Step Genetic Programming

Systems biology requires the development of algorithms that use omics data to infer interaction networks among biomolecules working within an organism. One major type of evolutionary algorithm, genetic programming (GP), is useful for its high heuristic ability as a search method for obtaining suitable solutions expressed as tree structures. However, because GP determines the values of parameters such as coefficients by random values, it is difficult to apply in the inference of state equations that describe oscillatory biochemical reaction systems with high nonlinearity. Accordingly, in this study, we propose a new GP procedure called “k-step GP” intended for inferring the state equations of oscillatory biochemical reaction systems. The k-step GP procedure consists of two algorithms: 1) Parameter optimization using the modified Powell method—after genetic operations such as crossover and mutation, the values of parameters such as coefficients are optimized by applying the modified Powell method with secondary convergence. 2) GP using divided learning data—to improve the inference efficiency, imposes perturbations through the addition of learning data at various intervals and adaptations to these changes result in state equations with higher fitness. We are confident that k-step GP is an algorithm that is particularly well suited to inferring state equations for oscillatory biochemical reaction systems and contributes to solving inverse problems in systems biology.

Max-plus-linear model-based predictive control for constrained hybrid systems: linear programming solution

In this paper, a linear programming method is proposed to solve model predictive control for a class of hybrid systems. Firstly, using the （max, ＋） algebra, a typical subclass of hybrid systems called max-plus-linear （MPL） systems is obtained. And then, model predictive control （MPC） framework is extended to MPL systems. In general, the nonlinear optimization approach or extended linear complementarity problem （ELCP） were applied to solve the MPL-MPC optimization problem. A new optimization method based on canonical forms for max-min-plus-scaling （MMPS） functions （using the operations maximization, minimization, addition and scalar multiplication） with linear constraints on the inputs is presented. The proposed approach consists in solving several linear programming problems and is more efficient than nonlinear optimization. The validity of the algorithm is illustrated by an example.

Modeling Dynamic Systems by Using the Nonlinear Difference Equations Based on Genetic Programming

When acquaintances of a model are little or the model is too complicate to build by using traditional time series methods, it is convenient for us to take advantage of genetic programming (GP) to build the model. Considering the complexity of nonlinear dynamic systems, this paper proposes modeling dynamic systems by using the nonlinear difference e-quation based on GP technique. First it gives the method, criteria and evaluation of modeling. Then it describes the modeling algorithm using GP. Finally two typical examples of time series are used to perform the numerical experiments. The result shows that this algorithm can successfully establish the difference equation model of dynamic systems and its predictive result is also satisfactory.

Stability of Nonlinear Systems Using Optimal Fuzzy Controllers and Its Simulation by Java Programming

In this paper, at first, the single input rule modules(SIRMs) dynamically connected fuzzy inference model is used to stabilize a double inverted pendulum system. Then, a multiobjective particle swarm optimization(MOPSO) is implemented to optimize the fuzzy controller parameters in order to decrease the distance error of the cart and summation of the angle errors of the pendulums, simultaneously. The feasibility and efficiency of the proposed Pareto front is assessed in comparison with results reported in literature and obtained from other algorithms.Finally, the Java programming with applets is utilized to simulate the stability of the nonlinear system and explain the internetbased control.

Combining Geographic Information Systems for Transportation and Mixed Integer Linear Programming in Facility Location-Allocation Problems

In this study, we aimed to assess the solution quality for location-allocation problems from facilities generated by the software TransCAD&reg;?, a Geographic Information System for Transportation (GIS-T). Such facilities were obtained after using two routines together: Facility Location and Transportation Problem, when compared with optimal solutions from exact mathematical models, based on Mixed Integer Linear Programming (MILP), developed externally for the GIS. The models were applied to three simulations: the first one proposes opening factories and customer allocation in the state of Sao Paulo, Brazil;the second involves a wholesaler and a study of location and allocation of distribution centres for retail customers;and the third one involves the location of day-care centers and allocation of demand (0 - 3 years old children). The results showed that when considering facility capacity, the MILP optimising model presents results up to 37% better than the GIS and proposes different locations to open new facilities.

Optimal Redundancy Allocation in Hierarchical Series-Parallel Systems Using Mixed Integer Programming

Reliability optimization plays an important role in design, operation and management of the industrial systems. System reliability can be easily enhanced by improving the reliability of unreliable components and/or by using redundant configuration with subsystems/components in parallel. Redundancy Allocation Problem (RAP) was studied in this research. A mixed integer programming model was proposed to solve the problem, which considers simultaneously two objectives under several resource constraints. The model is only for the hierarchical series-parallel systems in which the elements of any subset of subsystems or components are connected in series or parallel and constitute a larger subsystem or total system. At the end of the study, the performance of the proposed approach was evaluated by a numerical example.

Recent Progress in Reinforcement Learning and Adaptive Dynamic Programming for Advanced Control Applications

Reinforcement learning(RL) has roots in dynamic programming and it is called adaptive/approximate dynamic programming(ADP) within the control community. This paper reviews recent developments in ADP along with RL and its applications to various advanced control fields. First, the background of the development of ADP is described, emphasizing the significance of regulation and tracking control problems. Some effective offline and online algorithms for ADP/adaptive critic control are displayed, where the main results towards discrete-time systems and continuous-time systems are surveyed, respectively.Then, the research progress on adaptive critic control based on the event-triggered framework and under uncertain environment is discussed, respectively, where event-based design, robust stabilization, and game design are reviewed. Moreover, the extensions of ADP for addressing control problems under complex environment attract enormous attention. The ADP architecture is revisited under the perspective of data-driven and RL frameworks,showing how they promote ADP formulation significantly.Finally, several typical control applications with respect to RL and ADP are summarized, particularly in the fields of wastewater treatment processes and power systems, followed by some general prospects for future research. Overall, the comprehensive survey on ADP and RL for advanced control applications has d emonstrated its remarkable potential within the artificial intelligence era. In addition, it also plays a vital role in promoting environmental protection and industrial intelligence.

A Stochastic Programming Strategy in Microgrid Cyber Physical Energy System for Energy Optimal Operation

This paper focuses on the energy optimal operation problem of microgrids (MGs) under stochastic environment. The deterministic method of MGs operation is often uneconomical because it fails to consider the high randomness of unconventional energy resources. Therefore, it is necessary to develop a novel operation approach combining the uncertainty in the physical world with modeling strategy in the cyber system. This paper proposes an energy scheduling optimization strategy based on stochastic programming model by considering the uncertainty in MGs. The goal is to minimize the expected operation cost of MGs. The uncertainties are modeled based on autoregressive moving average (ARMA) model to expose the effects of physical world on cyber world. Through the comparison of the simulation results with deterministic method, it is shown that the effectiveness and robustness of proposed stochastic energy scheduling optimization strategy for MGs are valid. © 2014 Chinese Association of Automation.

Optimal Control for a Class of Complex Singular System Based on Adaptive Dynamic Programming

This paper presents a new design approach to achieve decentralized optimal control of high-dimension complex singular systems with dynamic uncertainties. Based on robust adaptive dynamic programming(robust ADP) method, controllers for solving the singular systems optimal control problem are designed. The proposed algorithm can work well when the system model is not exactly known but the input and output data can be measured. The policy iteration of each controller only uses their own states and input information for learning,and do not need to know the whole system dynamics. Simulation results on the New England 10-machine 39-bus test system show the effectiveness of the designed controller.

A Partial Parallel Airport Gate Assignment Supported by a Knowledge－based System Combined with Mathematical Programming

The gate assignment at an airport is one of the major activities in airport operations.With the increase of passenger traffic volumes and the number of flights, the complexity of this task and the factors to be considered have increased significantly, and an efficient gate utilizationhas received considerable attention. For overcoming the shortcomings of previous gate assignmentapproaches, this paper presents a partial parallel gate assignment approach, by which more factorsconcerning aircraft and gates can be collsidered at the same time. This paper also presents themethod of using a knowledge-based system combined with a mathematical programming method forgetting an optimized feasible assignment solution. By this way, it is more easily to get the solutionthat satisfies both the static and dynamic situations,and thus it may adapt well to meet the needsof actual use to rea-time operations. An experimental prototype has been implemented, and a casestudy is presented at the end of the paper.

Security Risk Assessment of Cyber Physical Power System Based on Rough Set and Gene Expression Programming

Risk assessment is essential for the safe and reliable operation of cyber physical power system. Traditional security risk assessment methods do not take integration of cyber system and physical system of power grid into account. In order to solve this problem, security risk assessment algorithm of cyber physical power system based on rough set and gene expression programming is proposed. Firstly, fast attribution reduction based on binary search algorithm is presented. Secondly, security risk assessment function for cyber physical power system is mined based on gene expression programming. Lastly, security risk levels of cyber physical power system are predicted and analyzed by the above function model. Experimental results show that security risk assessment function model based on the proposed algorithm has high efficiency of function mining, accuracy of security risk level prediction and strong practicality. © 2014 Chinese Association of Automation.

A Neuron-Oriented Programming System

A neruon-oriented programming system based on parallel neural information processing has been presented. With the neural programming system built upon 4～8 process elements(TMS C30), the system has thus provided users high speed, general purpose and large scale neural network application development platforms etc.

Reformative Financial Risk Management Approach： A Multistage Decision Support System with the Assistance of Fuzzy Goal Programming and Expertons Method

The potential demand on financial risk management has being increased considerably by the reason of Basel 11 regulations and instabilities in economy. In recent years, financial institutions and companies have been struggled for building up intensive financial risk management tools due to Basel II guidance on establishing financial self-assessment systems. In this respect, decision support system has a significant role on effectuating intensive financial risk management roadmap. In this study, a reformative financial risk management system is presented with the combination of determining financial risks with their importance, calculating risk scores and making suggestions based on detected risk scores by applying corrective actions. First, financial risk factors and indicators of these risk variables are selected and weights of these variables are specified by using fuzzy goal programming. After that, total risk scores are calculated and amendatory financial activities are appeared by means of expertons method which also provides possibilities of the alternative decisions. To illustrate the performance of integrated and multistage decision support system, a survey is applied on the end users.

Control strategy optimization using dynamic programming method for synergic electric system on hybrid electric vehicle

Dynamic Programming (DP) algorithm is used to find the optimal trajectories under Beijing cycle for the power management of synergic electric system (SES) which is composed of battery and super capacitor. Feasible rules are derived from analyzing the optimal trajectories, and it has the highest contribution to Hybrid Electric Vehicle (HEV). The methods of how to get the best performance is also educed. Using the new Rule-based power management strat-egy adopted from the optimal results, it is easy to demonstrate the effectiveness of the new strategy in further improvement of the fuel economy by the synergic hybrid system.

C-Language Programming for Development of Conventional Water Treatment Plants Decision Support System

Water-Decision Support System (DSS) tools enhance decision-makings towards improved water supply in a given region. The rigours of manual design of the conventional water treatment plants are easily eliminated with the use of softwares as in the case of DSS. Therefore, this paper focuses on the development of a Water-DSS for design of treatment plant in Karkala Town, Udupi District of India. A four-decade population projection was made using the baseline data of 1971 till date. The manual computation for water demand, unit operations and adjoining facilities was carried out and later coded in C-programming language for development of a DSS for easier design and process selection. Data validation was done and results from the two approaches were compared. With the C-programming technique, a decision support tool for design and process selection of drinking water treatment plant using conventional method has been developed and named Water-DSS1. The designed tool is simple, accurate, flexible, efficient and universal, easily adaptable to any similar conventional treatment plant. Water-DSS1 is thus recommended for general use in ultimately alleviating water supply challenges.

Intelligent Tutoring System of Linear Programming

There is a growing technological development in intelligent teaching systems. This field has become interesting to many researchers. In this paper, we present an intelligent tutoring system for teaching mathematics that helps students understand the basics of linear programming using Linear Program Solver and Service for Solving Linear Programming Problems, through which students will be able to solve economic problems. It comes down to determining the minimum or maximum value of a linear function, which is called the objective function, according to pre-set limiting conditions expressed by linear equations and inequalities. The goal function and the limiting conditions represent a mathematical model of the observed problem. Working as a professor of mathematics in high school, I felt the need for one such work and dealing with the study of linear programming as an integral part of mathematics. There are a number of papers in this regard, but exclusively related to traditional ways of working, as stated in the introductory part of the paper. The center of work as well as the final part deals with the study of linear programming using programs that deal with this topic.

Research and Development on NC System of Gear-hobbing Machine based on Zero-programming Technology

By the analysis of roller gear processing technology, combining with gear meshing mechanism and motion relationship, models for rolling gear machining parameter and zero-programming are established. In this paper, the automatic generation technology of NC program for CNC gear machining process has been studied and the zero-programming system architecture of open CNC gear-hobbing machine has been presented. In the design and development of the system, human computer interaction, programming algorithm and the design of each function module have bean done. Application test shows that the expected design requirements have been achieved.

Fund budget model for multipurpose transit smart card systems

The fund budget of multipurpose transit smart card systems is studied by stochastic programming to assign limited funds to different applications reasonably. Under the constraints of a gross fund, models of chance-constrained and dependentchance for the fund budget of multipurpose transit smart card systems are established with application scale and social demand as random variables, respectively aiming to maximize earnings and satisfy the service requirements the furthest; and the genetic algorithm based on stochastic simulation is adopted for model solution. The calculation results show that the fund budget differs greatly with different system objectives which can cause the systems to have distinct expansibilities, and the application scales of some applications may not satisfy user demands with limited funds. The analysis results indicate that the forecast of application scales and application future demands should be done first, and then the system objective is determined according to the system mission, which can help reduce the risks of fund budgets.

Agent Oriented Programming进展

Agent-oriented programming (AOP) is a framework to develop agents, and it aims to link the gap betweentheory and practical in agent research. The core of an AOP framework is its language and semantics. In this paper,we propose the necessary properties which agents should have, and then give a summary and analysis about differentAOP languages based on these properties.