Background: From the two facts reported by previous research: 1) frequent co-occurrence of more than one addictive behavior, 2) childhood adversities identified as origins of different types of addictive behaviors, it...Background: From the two facts reported by previous research: 1) frequent co-occurrence of more than one addictive behavior, 2) childhood adversities identified as origins of different types of addictive behaviors, it is assumed that all types of addictive behaviors, regardless of substance, behavioral, or relationship, share common factors which have not yet been proven by epidemiological research. The Shorter PROMIS Questionnaire (SPQ) was previously developed to assess 16 types of addictive behaviors. Its factor structure, however, has not been fully investigated. Confirming the factor structure will enable us to hypothesize the common factor(s) shared by all, or if not all, most types of addictive behaviors. Aims: This study aimed at 1) examining the factor structure of the SPQ, 2) confirming the reliability of the questionnaire, and 3) examining the impacts of gender and age on each addictive behavior. Methods: Data obtained from 232 Japanese adults who completed all items of the SPQ were used for the analyses. After confirming the one-factor structure model for each of the 16 subscales, the validity of the one-factor structure of the SPQ was evaluated using Confirmatory Factor Analysis (CFA), by adapting 16 subscale scores as observed variables. If its validity was not confirmed, another model which showed better compatibility to the data was explored. The reliability of the SPQ as well as that of all 16 subscales was evaluated. Also, the impacts of gender and age on each subscale score were examined. Results: The one-factor structure for each of the 16 subscales was confirmed. The compatibility of the SPQ one-factor model was not acceptable. The best fit model was a bi-factor model in which one main factor was shared by all 16 subscales, and three factors were shared by some specific addictive behaviors. Male respondents were more likely than female respondents to show high scores in Alcohol, Tobacco, Gambling, Sex, and Recreational Drugs, and low scores only in Shopping. Respondents’ age did not impact any of the 16 subscale scores. Conclusion: It was demonstrated that there are common factors shared by all different types, as well as selected types of addictive behaviors, by conducting CFAs of the SPQ. Reliability was proven for the SPQ and for all 16 subscales. Male respondents were more likely to show physically hedonic addictive behaviors.展开更多
目的评估中文版患者报告结局测量信息系统(Patient Reported Outcome Measurement Information System,PROMIS)癌症特异性抑郁项目库的心理测量学属性,构建计算机自适应测试版本(PROMIS Cancer Depression CAT),并评价其效果。方法采用...目的评估中文版患者报告结局测量信息系统(Patient Reported Outcome Measurement Information System,PROMIS)癌症特异性抑郁项目库的心理测量学属性,构建计算机自适应测试版本(PROMIS Cancer Depression CAT),并评价其效果。方法采用便利抽样法选取2020年11月—2021年7月在上海2所三级甲等医院的648例癌症患者作为研究对象。在心理测量学评估中,首先基于Rasch模型采用残差的主成分分析、条目残差相关系数、条目特征曲线检验PROMIS癌症特异性抑郁项目库的单维性、局部独立性、单调性假设;其次,通过Rasch模型中的选项特征曲线对选项进行拟合,采用Rasch模型中的Infit MNSQ、Outfit MNSQ、难度参数对每个条目进行拟合;最后,将经过校准后的项目库内容作为PROMIS Cancer Depression CAT的题库,采用Post-hoc模拟方法评价PROMIS Cancer Depression CAT的测量效率和准确性。结果PROMIS癌症特异性抑郁项目库由测试解释的经验方差为68.6%,条目之间的残差相关值都小于0.70,条目特征曲线是单调递增曲线。PROMIS癌症特异性抑郁项目库中的5个选项的峰值均未被相邻选项的特征曲线覆盖,5个选项之间阈值的间隔均大于1且小于5,条目的Infit MNSQ值为[0.54,1.49],Outfit MNSQ值为[0.55,1.49],选项和条目的拟合均在理想范围内,可作为构建PROMIS Cancer Depression CAT的项目库。Post-hoc模拟执行CAT的θ值与整个项目库的θ值相关系数为0.964,选择的平均使用条目数为6.348个。结论中文版PROMIS癌症特异性抑郁项目库满足单维性、局部独立性以及单调性假设,可以用来构建PROMIS Cancer Depression CAT。基于PROMIS癌症特异性抑郁项目库参数构建的计算机自适应测试版本能够高效、准确地测量癌症患者的抑郁水平。展开更多
目的初步构建基于工作流理念的患者报告结局测量信息系统中国中心(Patient‑reported Outcomes Measurement Information System National Center‑China,PNC‑China)信息化管理系统,优化PNCChina的管理流程。方法通过质性访谈了解PNC‑Chin...目的初步构建基于工作流理念的患者报告结局测量信息系统中国中心(Patient‑reported Outcomes Measurement Information System National Center‑China,PNC‑China)信息化管理系统,优化PNCChina的管理流程。方法通过质性访谈了解PNC‑China工作人员对信息化管理系统的构建需求及功能设想;结合工作流理论的三大要素,构建PNC‑China信息化管理系统初步框架。结果通过质性访谈归纳提炼出PNC‑China信息化管理需求的三大主题,即相关工作流程繁琐,急需信息化工具辅助;文件管理工具较落后,急需实现系统化、信息化管理;合作管理欠规范,急需实现标准化。结合需求及功能设想,构建出PNC‑China信息化管理系统的3个功能框架,即PROMIS中文版翻译工作流程框架、临床检验工作流程框架及临床应用工作流程框架。结论基于工作流理念,贴合PNC‑China工作内容和流程构建的信息化管理系统框架,将有助于推动我国患者报告结局测量信息系统的相关研究和临床实践。展开更多
提出了一种基于Promis·e设计环境的变电站电工二次专业协同设计方法,对协同平台的建立、制图标准化、设备模型库构建以及协同设计流程等协同设计中的一些关键环节进行了描述,并结合工程实践,给出了协同设计各关键点的应用实例及解...提出了一种基于Promis·e设计环境的变电站电工二次专业协同设计方法,对协同平台的建立、制图标准化、设备模型库构建以及协同设计流程等协同设计中的一些关键环节进行了描述,并结合工程实践,给出了协同设计各关键点的应用实例及解决方案。所提出的变电站二次接线协同设计方法,已经在10余座220 k V的变电站项目中得到了应用,它可以大幅度地提高设计效率,保证设计成果的质量,具有继承性、拓展性和参照性。展开更多
Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become...Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become vital tools for physicians to understand the effectiveness and value of treatment and care. Methods: This study was conducted in 2012 with 116 patients that took the EQ-5D-5L and a number of patient-reported outcome instruments in a university orthopaedic clinic. Regression analyses were conducted to predict EQ-5D-5L index scores from the LE CAT, PROMIS PF CAT, Depression CAT, and Pain CAT. Results: All predictors, separately or combined, significantly predicted the EQ-5D-5L index scores (p < 0.0001). The LE CAT was the best predictor;it alone accounted for 37% of the variability in the EQ-5D-5L. When combining patient-reported outcome measures, the best predicting model was the one consisting of the LE CAT, Depression CAT and Pain CAT;they explained for 43.9% of the variance in EQ-5D-5L. Conclusions: The findings provide encouraging news that the LE CAT, PF CAT, Depression CAT and Pain CAT can be used alone or in combination as a proxy for the EQ-5D-5L. Researchers have the options of using these patient-reported outcome measures for economic evaluations and medical intervention studies.展开更多
Chinese physicians find new methods to treat the disease After more than three hours of collection,299 ml of hematopoietic stem cell suspension was extracted from the body of Ji Guochen,a postman in Suzhou,capital cit...Chinese physicians find new methods to treat the disease After more than three hours of collection,299 ml of hematopoietic stem cell suspension was extracted from the body of Ji Guochen,a postman in Suzhou,capital city of east China’s Jiangsu Province,展开更多
The first part of this paper reviews our efforts on knowledge-based software engineering, namely PROMIS, started from 1990s. The key point of PROMIS is to generate applications automatically based on domain knowledge ...The first part of this paper reviews our efforts on knowledge-based software engineering, namely PROMIS, started from 1990s. The key point of PROMIS is to generate applications automatically based on domain knowledge as well as software knowledge. That is featured by separating the development of domain knowledge from the development of software. But in PROMIS, we did not find an appropriate representation for the domain knowledge. Fortunately, in our recent work, we found such a carrier for knowledge modules, i.e. knowware. Knowware is a commercialized form of domain knowledge. This paper briefly introduces the basic definitions of knowware, knowledge middleware and knowware engineering. Three life circle models of knowware engineering and the design of corresponding knowware implementations are given. Finally we discuss application system automatic generation and domain knowledge modeling on the J2EE platform, which combines the techniques of PROMIS, knowware and J2EE, and the development and deployment framework, i.e. PROMIS/KW＊＊.展开更多
1.大卫一直是个守信的人。David always keeps his word.2.玛丽老是取消诺言,认错道歉。Mary often eats her words.3.你说得挺有道理的。You’ve got a point here.4.你不会后悔的。You won’t regret it.5.你可以信得过我/相信我的话...1.大卫一直是个守信的人。David always keeps his word.2.玛丽老是取消诺言,认错道歉。Mary often eats her words.3.你说得挺有道理的。You’ve got a point here.4.你不会后悔的。You won’t regret it.5.你可以信得过我/相信我的话。You can have my word.展开更多
Lumena Resources Corp(HK:00067)waslisted on Hong Kong Exchanges and ClearingLimited on June 16th.Registered in Cayman Islands,Lumena Re-sources holds a 90% stake in Sichuan ProvinceChuanmei Mirabilite Co.,Ltd.and 100%...Lumena Resources Corp(HK:00067)waslisted on Hong Kong Exchanges and ClearingLimited on June 16th.Registered in Cayman Islands,Lumena Re-sources holds a 90% stake in Sichuan ProvinceChuanmei Mirabilite Co.,Ltd.and 100% inSichuan Province Chuanmei Special MirabiliteCo.,Ltd.through its wholly owned subsidiaryTop Promise.Top Promise was founded in2005 being registered in Hong Kong.展开更多
DuPont sales in emerging markets grew by80% in the past five years at a compoundedannual growth rate of 16%, and accountedfor nearly one-third of the company’sUS$30.5 billion sales in 2008. While 2009emerging market ...DuPont sales in emerging markets grew by80% in the past five years at a compoundedannual growth rate of 16%, and accountedfor nearly one-third of the company’sUS$30.5 billion sales in 2008. While 2009emerging market sales estimates are expectedto be down about 10% from US$9billion in 2008, the company projects 2012emerging market sales of about US$13billion, according to DuPont Executive展开更多
文摘Background: From the two facts reported by previous research: 1) frequent co-occurrence of more than one addictive behavior, 2) childhood adversities identified as origins of different types of addictive behaviors, it is assumed that all types of addictive behaviors, regardless of substance, behavioral, or relationship, share common factors which have not yet been proven by epidemiological research. The Shorter PROMIS Questionnaire (SPQ) was previously developed to assess 16 types of addictive behaviors. Its factor structure, however, has not been fully investigated. Confirming the factor structure will enable us to hypothesize the common factor(s) shared by all, or if not all, most types of addictive behaviors. Aims: This study aimed at 1) examining the factor structure of the SPQ, 2) confirming the reliability of the questionnaire, and 3) examining the impacts of gender and age on each addictive behavior. Methods: Data obtained from 232 Japanese adults who completed all items of the SPQ were used for the analyses. After confirming the one-factor structure model for each of the 16 subscales, the validity of the one-factor structure of the SPQ was evaluated using Confirmatory Factor Analysis (CFA), by adapting 16 subscale scores as observed variables. If its validity was not confirmed, another model which showed better compatibility to the data was explored. The reliability of the SPQ as well as that of all 16 subscales was evaluated. Also, the impacts of gender and age on each subscale score were examined. Results: The one-factor structure for each of the 16 subscales was confirmed. The compatibility of the SPQ one-factor model was not acceptable. The best fit model was a bi-factor model in which one main factor was shared by all 16 subscales, and three factors were shared by some specific addictive behaviors. Male respondents were more likely than female respondents to show high scores in Alcohol, Tobacco, Gambling, Sex, and Recreational Drugs, and low scores only in Shopping. Respondents’ age did not impact any of the 16 subscale scores. Conclusion: It was demonstrated that there are common factors shared by all different types, as well as selected types of addictive behaviors, by conducting CFAs of the SPQ. Reliability was proven for the SPQ and for all 16 subscales. Male respondents were more likely to show physically hedonic addictive behaviors.
文摘目的评估中文版患者报告结局测量信息系统(Patient Reported Outcome Measurement Information System,PROMIS)癌症特异性抑郁项目库的心理测量学属性,构建计算机自适应测试版本(PROMIS Cancer Depression CAT),并评价其效果。方法采用便利抽样法选取2020年11月—2021年7月在上海2所三级甲等医院的648例癌症患者作为研究对象。在心理测量学评估中,首先基于Rasch模型采用残差的主成分分析、条目残差相关系数、条目特征曲线检验PROMIS癌症特异性抑郁项目库的单维性、局部独立性、单调性假设;其次,通过Rasch模型中的选项特征曲线对选项进行拟合,采用Rasch模型中的Infit MNSQ、Outfit MNSQ、难度参数对每个条目进行拟合;最后,将经过校准后的项目库内容作为PROMIS Cancer Depression CAT的题库,采用Post-hoc模拟方法评价PROMIS Cancer Depression CAT的测量效率和准确性。结果PROMIS癌症特异性抑郁项目库由测试解释的经验方差为68.6%,条目之间的残差相关值都小于0.70,条目特征曲线是单调递增曲线。PROMIS癌症特异性抑郁项目库中的5个选项的峰值均未被相邻选项的特征曲线覆盖,5个选项之间阈值的间隔均大于1且小于5,条目的Infit MNSQ值为[0.54,1.49],Outfit MNSQ值为[0.55,1.49],选项和条目的拟合均在理想范围内,可作为构建PROMIS Cancer Depression CAT的项目库。Post-hoc模拟执行CAT的θ值与整个项目库的θ值相关系数为0.964,选择的平均使用条目数为6.348个。结论中文版PROMIS癌症特异性抑郁项目库满足单维性、局部独立性以及单调性假设,可以用来构建PROMIS Cancer Depression CAT。基于PROMIS癌症特异性抑郁项目库参数构建的计算机自适应测试版本能够高效、准确地测量癌症患者的抑郁水平。
文摘目的初步构建基于工作流理念的患者报告结局测量信息系统中国中心(Patient‑reported Outcomes Measurement Information System National Center‑China,PNC‑China)信息化管理系统,优化PNCChina的管理流程。方法通过质性访谈了解PNC‑China工作人员对信息化管理系统的构建需求及功能设想;结合工作流理论的三大要素,构建PNC‑China信息化管理系统初步框架。结果通过质性访谈归纳提炼出PNC‑China信息化管理需求的三大主题,即相关工作流程繁琐,急需信息化工具辅助;文件管理工具较落后,急需实现系统化、信息化管理;合作管理欠规范,急需实现标准化。结合需求及功能设想,构建出PNC‑China信息化管理系统的3个功能框架,即PROMIS中文版翻译工作流程框架、临床检验工作流程框架及临床应用工作流程框架。结论基于工作流理念,贴合PNC‑China工作内容和流程构建的信息化管理系统框架,将有助于推动我国患者报告结局测量信息系统的相关研究和临床实践。
文摘提出了一种基于Promis·e设计环境的变电站电工二次专业协同设计方法,对协同平台的建立、制图标准化、设备模型库构建以及协同设计流程等协同设计中的一些关键环节进行了描述,并结合工程实践,给出了协同设计各关键点的应用实例及解决方案。所提出的变电站二次接线协同设计方法,已经在10余座220 k V的变电站项目中得到了应用,它可以大幅度地提高设计效率,保证设计成果的质量,具有继承性、拓展性和参照性。
文摘Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become vital tools for physicians to understand the effectiveness and value of treatment and care. Methods: This study was conducted in 2012 with 116 patients that took the EQ-5D-5L and a number of patient-reported outcome instruments in a university orthopaedic clinic. Regression analyses were conducted to predict EQ-5D-5L index scores from the LE CAT, PROMIS PF CAT, Depression CAT, and Pain CAT. Results: All predictors, separately or combined, significantly predicted the EQ-5D-5L index scores (p < 0.0001). The LE CAT was the best predictor;it alone accounted for 37% of the variability in the EQ-5D-5L. When combining patient-reported outcome measures, the best predicting model was the one consisting of the LE CAT, Depression CAT and Pain CAT;they explained for 43.9% of the variance in EQ-5D-5L. Conclusions: The findings provide encouraging news that the LE CAT, PF CAT, Depression CAT and Pain CAT can be used alone or in combination as a proxy for the EQ-5D-5L. Researchers have the options of using these patient-reported outcome measures for economic evaluations and medical intervention studies.
文摘Chinese physicians find new methods to treat the disease After more than three hours of collection,299 ml of hematopoietic stem cell suspension was extracted from the body of Ji Guochen,a postman in Suzhou,capital city of east China’s Jiangsu Province,
基金the National Natural Science Foundation of China for Distinguished Young Scholars (Grant No. 60625204)the Key Project of National Natural Science Foundation of China (Grant Nos. 60736011, 60496324 and 60603002)
文摘The first part of this paper reviews our efforts on knowledge-based software engineering, namely PROMIS, started from 1990s. The key point of PROMIS is to generate applications automatically based on domain knowledge as well as software knowledge. That is featured by separating the development of domain knowledge from the development of software. But in PROMIS, we did not find an appropriate representation for the domain knowledge. Fortunately, in our recent work, we found such a carrier for knowledge modules, i.e. knowware. Knowware is a commercialized form of domain knowledge. This paper briefly introduces the basic definitions of knowware, knowledge middleware and knowware engineering. Three life circle models of knowware engineering and the design of corresponding knowware implementations are given. Finally we discuss application system automatic generation and domain knowledge modeling on the J2EE platform, which combines the techniques of PROMIS, knowware and J2EE, and the development and deployment framework, i.e. PROMIS/KW＊＊.
文摘1.大卫一直是个守信的人。David always keeps his word.2.玛丽老是取消诺言,认错道歉。Mary often eats her words.3.你说得挺有道理的。You’ve got a point here.4.你不会后悔的。You won’t regret it.5.你可以信得过我/相信我的话。You can have my word.
文摘Lumena Resources Corp(HK:00067)waslisted on Hong Kong Exchanges and ClearingLimited on June 16th.Registered in Cayman Islands,Lumena Re-sources holds a 90% stake in Sichuan ProvinceChuanmei Mirabilite Co.,Ltd.and 100% inSichuan Province Chuanmei Special MirabiliteCo.,Ltd.through its wholly owned subsidiaryTop Promise.Top Promise was founded in2005 being registered in Hong Kong.
文摘DuPont sales in emerging markets grew by80% in the past five years at a compoundedannual growth rate of 16%, and accountedfor nearly one-third of the company’sUS$30.5 billion sales in 2008. While 2009emerging market sales estimates are expectedto be down about 10% from US$9billion in 2008, the company projects 2012emerging market sales of about US$13billion, according to DuPont Executive
