Although trifluoromethylthiolated compounds have privileged applications in pharmaceuticals and agrochemicals,efficient strategies for the asymmetric construction of C_(sp)^(3)-SCF_(3)bonds are limited.Specifically,th...Although trifluoromethylthiolated compounds have privileged applications in pharmaceuticals and agrochemicals,efficient strategies for the asymmetric construction of C_(sp)^(3)-SCF_(3)bonds are limited.Specifically,the catalytic asymmetric nucleophilic trifluoromethylthiolation remains challenging.Here,we report a copper-catalyzed enantioselective nucleophilic trifluoromethylthiolation of secondary propargyl sulfonates with trifluoromethylthio silver.The reaction exhibits high efficiency,good enantioselectivity,high functional group tolerance,and broad substrate scope,paving a new way for the asymmetric synthesis of trifluoromethylthiolated compounds.展开更多
In the presence of p-toluene sulfonic acid (TSA) as a dopant, polyaniline (PAni) nanofibers, (about 80^-65 nm in diameter) were successfully synthesized with a chemical template-free method. It was found that the form...In the presence of p-toluene sulfonic acid (TSA) as a dopant, polyaniline (PAni) nanofibers, (about 80^-65 nm in diameter) were successfully synthesized with a chemical template-free method. It was found that the formation probability, morphology, and diameter of the resulting PAni-TSA nanofibers were sensitive to the synthetic conditions, such as reaction temperature, the molar ratio of TSA to aniline, and the concentration of TSA in the polymerization media. The molecular structure was characterized by using the FT-IR, Raman spectra and X-ray diffraction, which shows that the main chain structure of PAni-TSA nanofibers was in agreement with that of granular PAni.展开更多
基金Financial support for this work was provided by the National Natural Science Foundation of China(nos.21931013,21702225,21672238,and 21421002)the Strategic Priority Research Program of the Chinese Academy of Sciences(no.XDB20000000).
文摘Although trifluoromethylthiolated compounds have privileged applications in pharmaceuticals and agrochemicals,efficient strategies for the asymmetric construction of C_(sp)^(3)-SCF_(3)bonds are limited.Specifically,the catalytic asymmetric nucleophilic trifluoromethylthiolation remains challenging.Here,we report a copper-catalyzed enantioselective nucleophilic trifluoromethylthiolation of secondary propargyl sulfonates with trifluoromethylthio silver.The reaction exhibits high efficiency,good enantioselectivity,high functional group tolerance,and broad substrate scope,paving a new way for the asymmetric synthesis of trifluoromethylthiolated compounds.
文摘In the presence of p-toluene sulfonic acid (TSA) as a dopant, polyaniline (PAni) nanofibers, (about 80^-65 nm in diameter) were successfully synthesized with a chemical template-free method. It was found that the formation probability, morphology, and diameter of the resulting PAni-TSA nanofibers were sensitive to the synthetic conditions, such as reaction temperature, the molar ratio of TSA to aniline, and the concentration of TSA in the polymerization media. The molecular structure was characterized by using the FT-IR, Raman spectra and X-ray diffraction, which shows that the main chain structure of PAni-TSA nanofibers was in agreement with that of granular PAni.