Schisanpropinoic acid(1),a new bergamotane sesquiterpenoid,and schisanpropinin(2),a new tetrahydrofuran lignan with a rare epoxyethane unit,were identified from the stems and leaves of Schisandra propinqua var.propinq...Schisanpropinoic acid(1),a new bergamotane sesquiterpenoid,and schisanpropinin(2),a new tetrahydrofuran lignan with a rare epoxyethane unit,were identified from the stems and leaves of Schisandra propinqua var.propinqua.Their structures were determined based on comprehensive spectroscopic and mass spectrometric analysis.The absolute configuration of 1 was determined by X-ray analysis.Compounds 1 and 2 were tested for their cytotoxic activity against five human tumor cell lines.展开更多
Four new tetrahydrofuran lignans,schpropinrins A-D(1-4),together with five known ones,were isolated from the leaves and stems of Schisandra propinqua var.sinensis.Their structures,including absolute configurations,wer...Four new tetrahydrofuran lignans,schpropinrins A-D(1-4),together with five known ones,were isolated from the leaves and stems of Schisandra propinqua var.sinensis.Their structures,including absolute configurations,were characterized by means of spectroscopic analysis and ECD calculation.Compounds 1-4 featured a ketal or hemiketal substructure at C-7 and all of the isolates were tested for their anti-HIV integrase activity.展开更多
A new cinnamic acid monoterpenoid ester, intermedin C （1）, was isolated from the aerial parts of Schisandra propinqua var. interthedia. The structure of 1 was elucidated by spectroscopic methods including extensive ...A new cinnamic acid monoterpenoid ester, intermedin C （1）, was isolated from the aerial parts of Schisandra propinqua var. interthedia. The structure of 1 was elucidated by spectroscopic methods including extensive ^1D and 2D NMR techniques.展开更多
There are no previous records about planting bamboo in Changli, Hebei Province, north China. Since they were introduced in 2004, the propinquity bamboo （Phyllostachys propinqua McClure） has demonstrated good adaptab...There are no previous records about planting bamboo in Changli, Hebei Province, north China. Since they were introduced in 2004, the propinquity bamboo （Phyllostachys propinqua McClure） has demonstrated good adaptability to the cold climate in Changli. The overwintering status of the bamboo and some of its physiological changes after the winter have been studied to ascer- tain the adaptability of the bamboo to the cold weather in Changli and to establish a firm basis for growing the plants in larger areas in northern China. The bamboo lived through the winter without any protection. The leaves of windward bamboos growing at various intervals have been studied for their viability and health after the winter. The changes in some physiological indices of the leaves were measured in the following spring. Results showed that the bamboo is partly green even at a temperature as low as -22.3℃ in Changli. During the winter, some leaves died and some partly died. Leaves are light in color and turn gradually to a dark green when the temperature increases in the following spring. As new leaves develop, the contents of chlorophyll and water and the ratio of fi＇ee and bound water in the old leaves increase as does transpiration. At the same time the contents of free amino acid, proline, soluble sugar, malondialdehede （MDA）, permeability of the membrane, superoxide dismutase （SOD） and peroxidase （POD） activities de- crease. The direction of these physiological indices changes when the new leaves begin to sprout. The old leaves reduce their rate of photosynthesis, their blade functions decline gradually and the leaves fall off towards the middle of June. The cold wind affects the survival of bamboo leaves in winter, but has little effect on new leaves growing at the start of the following year. The results indicate that the propinquity bamboo can survive the winter in Changli quite well.展开更多
In the course of our study of bioactive natural products from Schisandra plants, we isolated a neolignan from an EtOAc extract of the stems of Schisandra propinqua （Wall.） Baill. The structure of the new com- pound ...In the course of our study of bioactive natural products from Schisandra plants, we isolated a neolignan from an EtOAc extract of the stems of Schisandra propinqua （Wall.） Baill. The structure of the new com- pound was determined to be 4, 4-di （4-hydroxy-3-methoxyphenly）-2, 3-dimethylbutanol （compound 1） on the basis of 1H- and 13C-NMR spectra and 2D NMR methods. Eight known compounds, compounds 2-9, were also isolated and identified, of which compounds 3, 4, 6 and 9 were isolated for the first time from this plant. In addition, compounds 1-4 were evaluated for cytotoxicity by an 3-（4,5-dimethyl-2 thiazoyl）-2,5-diphenyl-2H- tetrazolium bromide （MTT） assay. Compound 1 showed significant potential cytotoxic ability in the bioassay.展开更多
Eight dibenzocyclooctadiene lignans were isolated from the stems of Schisandra propinqua(Wall.)Hook. f. et Thoms. Their structures were elucidated as acetylgomisin R(1), angeloylgomisin R(2), gomisins A(3), B(4), N(5)...Eight dibenzocyclooctadiene lignans were isolated from the stems of Schisandra propinqua(Wall.)Hook. f. et Thoms. Their structures were elucidated as acetylgomisin R(1), angeloylgomisin R(2), gomisins A(3), B(4), N(5) and O(6), 6 O benzoylgomosin O(7) and schisantherin A(8) by spectral studies. Among them, compound 1 was a new one, compound 2 was discovered in the genus Schisandra for the first time and the others were originally isolated from Schisandra propinqua .展开更多
基金the National Natural Science Foundation of China(81373290 and 21322204).
文摘Schisanpropinoic acid(1),a new bergamotane sesquiterpenoid,and schisanpropinin(2),a new tetrahydrofuran lignan with a rare epoxyethane unit,were identified from the stems and leaves of Schisandra propinqua var.propinqua.Their structures were determined based on comprehensive spectroscopic and mass spectrometric analysis.The absolute configuration of 1 was determined by X-ray analysis.Compounds 1 and 2 were tested for their cytotoxic activity against five human tumor cell lines.
基金the NSFC(No.20802082 and 30830115)the projects from the Chinese Academy of Sciences(KSCX2-EW-Q-10 and KSCX1-YW-R-24)+1 种基金the Major State Basic Research Development Program of China(No.2009CB522303 and 2009CB940900)the Natural Science Foundation of Yunnan Province(No.2012FB178)。
文摘Four new tetrahydrofuran lignans,schpropinrins A-D(1-4),together with five known ones,were isolated from the leaves and stems of Schisandra propinqua var.sinensis.Their structures,including absolute configurations,were characterized by means of spectroscopic analysis and ECD calculation.Compounds 1-4 featured a ketal or hemiketal substructure at C-7 and all of the isolates were tested for their anti-HIV integrase activity.
基金supported by the National Natural Science Foundation of China (No.20402016)a Foundation for the Author of National Excellent Doctoral Dissertation of PR China (No.200780)+2 种基金a Foundation for the Author of Excellent Doctoral Dissertation of Chinese Academy of Sciences (No.00602551221)the Program for New Century Excellent Talents on University (No.NCET-06-0824)the Young Academic and Technical Leader Raising Foundation of Yunnan Province (No.2005py01-32).
文摘A new cinnamic acid monoterpenoid ester, intermedin C （1）, was isolated from the aerial parts of Schisandra propinqua var. interthedia. The structure of 1 was elucidated by spectroscopic methods including extensive ^1D and 2D NMR techniques.
文摘There are no previous records about planting bamboo in Changli, Hebei Province, north China. Since they were introduced in 2004, the propinquity bamboo （Phyllostachys propinqua McClure） has demonstrated good adaptability to the cold climate in Changli. The overwintering status of the bamboo and some of its physiological changes after the winter have been studied to ascer- tain the adaptability of the bamboo to the cold weather in Changli and to establish a firm basis for growing the plants in larger areas in northern China. The bamboo lived through the winter without any protection. The leaves of windward bamboos growing at various intervals have been studied for their viability and health after the winter. The changes in some physiological indices of the leaves were measured in the following spring. Results showed that the bamboo is partly green even at a temperature as low as -22.3℃ in Changli. During the winter, some leaves died and some partly died. Leaves are light in color and turn gradually to a dark green when the temperature increases in the following spring. As new leaves develop, the contents of chlorophyll and water and the ratio of fi＇ee and bound water in the old leaves increase as does transpiration. At the same time the contents of free amino acid, proline, soluble sugar, malondialdehede （MDA）, permeability of the membrane, superoxide dismutase （SOD） and peroxidase （POD） activities de- crease. The direction of these physiological indices changes when the new leaves begin to sprout. The old leaves reduce their rate of photosynthesis, their blade functions decline gradually and the leaves fall off towards the middle of June. The cold wind affects the survival of bamboo leaves in winter, but has little effect on new leaves growing at the start of the following year. The results indicate that the propinquity bamboo can survive the winter in Changli quite well.
文摘In the course of our study of bioactive natural products from Schisandra plants, we isolated a neolignan from an EtOAc extract of the stems of Schisandra propinqua （Wall.） Baill. The structure of the new com- pound was determined to be 4, 4-di （4-hydroxy-3-methoxyphenly）-2, 3-dimethylbutanol （compound 1） on the basis of 1H- and 13C-NMR spectra and 2D NMR methods. Eight known compounds, compounds 2-9, were also isolated and identified, of which compounds 3, 4, 6 and 9 were isolated for the first time from this plant. In addition, compounds 1-4 were evaluated for cytotoxicity by an 3-（4,5-dimethyl-2 thiazoyl）-2,5-diphenyl-2H- tetrazolium bromide （MTT） assay. Compound 1 showed significant potential cytotoxic ability in the bioassay.
文摘Eight dibenzocyclooctadiene lignans were isolated from the stems of Schisandra propinqua(Wall.)Hook. f. et Thoms. Their structures were elucidated as acetylgomisin R(1), angeloylgomisin R(2), gomisins A(3), B(4), N(5) and O(6), 6 O benzoylgomosin O(7) and schisantherin A(8) by spectral studies. Among them, compound 1 was a new one, compound 2 was discovered in the genus Schisandra for the first time and the others were originally isolated from Schisandra propinqua .
