Three hundred and eight patients with hepatocellular carcinoma underwent radical resection during 1975- 1991.The 1-,2-, 3-,4-,5-,and 10-year recurrent rates were 12.7%,28.7%,41.2%, 47.5%,54.1% and 64.4% respectively.B...Three hundred and eight patients with hepatocellular carcinoma underwent radical resection during 1975- 1991.The 1-,2-, 3-,4-,5-,and 10-year recurrent rates were 12.7%,28.7%,41.2%, 47.5%,54.1% and 64.4% respectively.By the end of March 1992,recurrence had occurred in 134 patients.Risk factors for recurrence were analyzed.Cox univariate analysts identified the following five factors to be correlated with increasing risk: high γ-GT,discovery by clinical,macronodular cirrhosis,minor resection and portal vein embolus.However,only high γ-GT,macronodular cirrhosis,and minor resection have been proved significant risk factors for recurrence in Cox multivariate analysis.Larger hepatic resection might reduce recurrence,intra-andlor post-operation comprehensive treatments are adevocated.展开更多
文摘Three hundred and eight patients with hepatocellular carcinoma underwent radical resection during 1975- 1991.The 1-,2-, 3-,4-,5-,and 10-year recurrent rates were 12.7%,28.7%,41.2%, 47.5%,54.1% and 64.4% respectively.By the end of March 1992,recurrence had occurred in 134 patients.Risk factors for recurrence were analyzed.Cox univariate analysts identified the following five factors to be correlated with increasing risk: high γ-GT,discovery by clinical,macronodular cirrhosis,minor resection and portal vein embolus.However,only high γ-GT,macronodular cirrhosis,and minor resection have been proved significant risk factors for recurrence in Cox multivariate analysis.Larger hepatic resection might reduce recurrence,intra-andlor post-operation comprehensive treatments are adevocated.