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Varieties of Chinese Traditional Medicines Protected by the State (Part One)
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《China's Foreign Trade》 1996年第5期28-32,共5页
Approved by the Ministry of Public Health,the following Medicines,producedby the named enterprises,are listed as varieties of Chinese traditionalmedicines that are protected by the state.
关键词 ORAL CO Part One varieties of chinese traditional medicines Protected by the State
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Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis 被引量:23
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作者 Jun Li Shu Zhang +2 位作者 Rui Zhou Jian Zhang Zong-Fang Li 《World Journal of Gastroenterology》 SCIE CAS 2017年第20期3615-3623,共9页
Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popu... Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is one of the most popular complementary and alternative medicine modalities worldwide for the treatment of AP.The current evidence from basic research and clinical studies has shown that TCM has good therapeutic effects on AP.This review summarizes the widely used formulas,single herbs and monomers that are used to treat AP and the potential underlying mechanisms of TCM.Because of the abundance,low cost,and safety of TCM as well as its ability to target various aspects of the pathogenesis,TCM provides potential clinical benefits and a new avenue with tremendous potential for the future treatment of AP. 展开更多
关键词 Acute pancreatitis traditional chinese medicine Alternative therapy Pancreas protection ANTI-INFLAMMATORY
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Mechanisms and status of research on the protective effects of traditional Chinese medicine against ischemic brain injury 被引量:1
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作者 Zhe-Tao Zhang Cheng-Yun Hu +2 位作者 Fei-Biao Dai Fei Tang Chao-Liang Tang 《Traditional Medicine Research》 2022年第1期35-43,共9页
Ischemic brain injury occurs when the metabolic needs of brain tissue cannot be met due to insufficient blood supply to the brain.It is one of the main causes of death and adult disability worldwide.The recurrence rat... Ischemic brain injury occurs when the metabolic needs of brain tissue cannot be met due to insufficient blood supply to the brain.It is one of the main causes of death and adult disability worldwide.The recurrence rate of ischemic brain injury is high.It places a heavy economic burden on families and society,and seriously affects human health and quality of life.In traditional Chinese medicine,ischemic stroke belongs to the category of“stroke”.The use of traditional Chinese medicine to treat stroke has a long history.After years of experimental research,a large amount of theoretical knowledge and practical experience have been accumulated.Promoting blood circulation and removing blood stasis is the basis of traditional Chinese medicine theory on the treatment of ischemic stroke.Commonly used single Chinese medicines include Chuangxiong(Ligusticum chuanxiong hort),Danggui(Angelica sinensis),Danshen(Salvia miltiorrhiza Bunge),Honghua(Carthamus tinctorius L.),Mudanpi(Moutan Cortex),and Huangqi(Astragali Radix).Buyang Huanwu decoction,Xinglou Chengqi decoction,Taohong Siwu decoction,and other traditional Chinese medicine prescriptions are believed to have a protective effect against brain damage caused by ischemic stroke.With the development of modern medical technology,the mechanism of traditional Chinese medicine treatments for ischemic brain injury has gradually been explored.This article reviews the mechanisms of traditional Chinese medicine’s protection against ischemic brain injury and its current clinical application. 展开更多
关键词 traditional chinese medicine ischemic brain injury STROKE brain protection clinical application
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Research progress of protective effect of traditional Chinese medicine on brain cells
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作者 Shu-Han Wang 《TMR Aging》 2020年第1期6-10,共5页
Objective:To review the protective effect of traditional Chinese medicine(TCM)on brain cells.Methods:The domestic journals and literature are searched and reviewed,classifies them according to the mechanisms of TCM,su... Objective:To review the protective effect of traditional Chinese medicine(TCM)on brain cells.Methods:The domestic journals and literature are searched and reviewed,classifies them according to the mechanisms of TCM,summaries their protective effect on brain cells.Results:Some single medicine and prescriptions possess a variety of biological activity,and has a protective effect on brain cells.Conclusion:Some TCM possess a variety of biological activity and have a protective effect on brain cells,so there are broad prospects to develop and apply these TCM. 展开更多
关键词 traditional chinese MEDICINE BRAIN cells Protective effect Research PROGRESS
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Study on Effect of Zhixinkang Capsule(脂欣康胶囊)in TreatingUnstable Effort Angina and Hyperlipidemia and Its Function in Vascular Endothelium Protection 被引量:5
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作者 张文高 颜亭祥 +7 位作者 高福军 孟宪忠 刘建平 尹格平 刘丽莉 罗南萍 史炳娥 马学盛 《Chinese Journal of Integrated Traditional and Western Medicine》 2003年第1期25-30,共6页
Objective:To observe the clinical effect and protection of vascular endothelium of Zhixin-kang Capsule (ZXKC) in middle-aged and old people with unstable effort angina and hyperlipidemia. Methods: Sixty-five patients ... Objective:To observe the clinical effect and protection of vascular endothelium of Zhixin-kang Capsule (ZXKC) in middle-aged and old people with unstable effort angina and hyperlipidemia. Methods: Sixty-five patients with unstable effort angina were randomly divided into ZXKC group (34 cases) and control group (31 cases). Conventional western medical therapy was given to both groups, with ZXKC group receiving additional ZXKC treatment. Data of 20 healthy persons were taken as normal group. Forty-eight patients with hyperlipidemia were divided into ZXKC group treated with ZXKC (31 cases) and control group treated with Yixintong (17 cases). The changes of clinical symptoms and laboratory indexes in all the patients were observed before and after treatment. Results: In patients with unstable effort angina, the efficacy of treatment of ZXKC, the withdrawal rate of nitroglycerin, the relieving of symptoms, the improvement of the electrocardiogram, the counts of circulating endothelial cells, the content of platelet P-selectin, the content of plasma endothelin (ET), the activity of superoxide dismutase (SOD) and the activity of malonyldialdehyde (MDA) were all better than those in the control group. In patients with hyperlipidemia, there was no significant difference in lipids reduction between ZXKC group and the control group. In both groups, the total cholesterol (TC), triglyceride (TG), low density lipo-protein-cholesterol (LDL-C), lipoprotein(a) [Lp(a)] , ET, oxidized low density lipoprotein, MDA, arte-riosclerotic index (AI) all lowered obviously, while the SOD, HDL-C and calcitonin gene-related peptide (CGRP) were all elevated markedly. In the ZXKC group, the nitric oxide(NO) increased significantly whereas the ET/CGRP and ET/NO decreased markedly. The total effective rate in symptom relieving, the markedly effective rate, the reduction of TC, ET and ET/CGRP, and the elevation of SOD in ZXKC group were all superior to those in the control group. Conclusion: ZXKC could effectively resist myocardial ischemia, relieve angina, reduce blood lipids, protect vascular endothelial cells, inhibit the activation of platelets, and resist lipid peroxidation. 展开更多
关键词 unstable effort angina HYPERLIPIDEMIA Zhixinkang capsule protection of vascular endo-thelium therapy of traditional chinese medicine
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Traditional Chinese medicine for vascular protection in ischemic stroke
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作者 Yiyu Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2008年第12期1390-1392,共3页
Although new drugs and intervention strategies have emerged from recent studies of neuroprotection, compared with haemodynamic and hemorheologic factors, knowledge of vascular factors of ischemic stroke is rather limi... Although new drugs and intervention strategies have emerged from recent studies of neuroprotection, compared with haemodynamic and hemorheologic factors, knowledge of vascular factors of ischemic stroke is rather limited. In practical terms, any strategy shown to reduce the incidence of fatal and nonfatal vascular events can be termed "vascular protection", including anti-thrombotic and anti-hypertensive therapies, as well as agents that directly benefit vascular endothelium. Vascular events include myocardial infarction, stroke, and claudication. Factors involved in these events include statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers. In traditional Chinese medicine, the principles of "activating blood circulation to remove stasis", "tonifying the kidney and replenishing the essence", "dispelling pathogenic wind and removing obstruction from the meridians", and "warming Yang and promoting water metabolism" are possibly related to vascular protection. However, more evidence is needed to correlate these positive effects with vascular protection. 展开更多
关键词 ischemic stroke NEUROprotection traditional chinese medicine vascular protection
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Study on the Psychological Mechanism and Application of Horticultural Therapy
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作者 Gongyi CHEN Ni LI Tao CHEN 《Meteorological and Environmental Research》 CAS 2021年第3期53-54,61,共3页
Horticultural therapy has a long history,and its application in China has been delayed for more than 20 years than that in the United States and the United Kingdom.The psychological mechanism of horticultural therapy ... Horticultural therapy has a long history,and its application in China has been delayed for more than 20 years than that in the United States and the United Kingdom.The psychological mechanism of horticultural therapy is mainly to improve emotional cognition and emotional state,and promote physical and mental health.Based on the character of traditional Chinese medicine,combined with the modern probiotics and the environmental protection measures of sewage treatment,the research of preventing and treating insomnia and depression was carried out by using the living Chinese herbal medicine ecosystem,and good results were obtained.Based on the concepts of traditional Chinese medicine,big health and environment protection,the mechanism of horticultural therapy should be further studied.Horticultural therapy should be integrated extensively in the construction of landscaping,to construct horticultural therapy system with Chinese characteristics. 展开更多
关键词 Horticultural therapy Psychological mechanism traditional chinese medicine Big health Environmental protection
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浅析天津中药炮制技术的形成、发展与特色
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作者 吴环宇 臧滨 +2 位作者 柴士伟 欧阳慧子 陈鹏 《天津中医药大学学报》 CAS 2024年第8期736-744,共9页
天津中药饮片炮制起源于明代,成于清代,独具地方特色。为了传承与发扬天津中药炮制特色,文章通过整理文献书籍和《天津中药饮片炮制规范》2022版,分析了天津中药炮制技术的形成、发展与特色。天津中药炮制优选道地药材;修治与软化药材... 天津中药饮片炮制起源于明代,成于清代,独具地方特色。为了传承与发扬天津中药炮制特色,文章通过整理文献书籍和《天津中药饮片炮制规范》2022版,分析了天津中药炮制技术的形成、发展与特色。天津中药炮制优选道地药材;修治与软化药材技术多样;切制技术兼容并蓄;辅料使用丰富多彩,重用醋与黄酒,善用甘草水炮制解毒;炮炙技术丰富,醋煮技术独具特色,通过比较《中国药典》2020版与其他地方中药材与饮片标准,挖掘出一些特色炮制品种。经过本文的挖掘与分析,可以为天津中药炮制的继承、发展与推广提供参考。 展开更多
关键词 天津中药炮制 特色炮制技术 特色炮制品种
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基于“筋、节、骨、髓”分型探讨神经根型颈椎病的手法治疗
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作者 李永津 林方政 +6 位作者 陈树东 詹吉恒 侯宇 祁冀 曾小龙 高梓博 林定坤 《广州中医药大学学报》 CAS 2024年第10期2596-2600,共5页
神经根型颈椎病(CSR)是一种由于颈椎间盘和椎间关节退变引起的疾病,主要表现为颈部、肩部及上肢神经支配区域的疼痛、感觉异常和运动障碍。传统中医的筋骨辨证在治疗该病时存在概念不清、辨证分型不一等问题。岐黄学者林定坤教授在筋骨... 神经根型颈椎病(CSR)是一种由于颈椎间盘和椎间关节退变引起的疾病,主要表现为颈部、肩部及上肢神经支配区域的疼痛、感觉异常和运动障碍。传统中医的筋骨辨证在治疗该病时存在概念不清、辨证分型不一等问题。岐黄学者林定坤教授在筋骨辨证的基础上,结合现代解剖学提出了颈椎“筋”“节”“骨”“髓”4大分型。该文通过总结林定坤教授对CSR筋骨辨证学术思想,总结手法治疗该病的作用靶点,提出基于筋劳、节错、骨变和髓损等4种病损分型,采用理筋、调节、护髓和治骨4种手法治疗,以期完善骨伤科手法治疗CSR的辨证施治体系,为临床提供参考。 展开更多
关键词 筋骨辨证 筋骨平衡 神经根型颈椎病 中医手法 理筋 调节 护髓 治骨 林定坤
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中医药传统知识专门保护制度构建研究
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作者 马治国 占妮 《知识产权》 北大核心 2024年第2期107-126,共20页
中医药传统知识是中医药的核心内容,兼具卫生、经济、科技、文化、生态五重资源价值。目前中医药传统知识面临国外不当占有、盗用,国内传承、保护不力的双重困局,现行法律制度无法实现全面、系统保护,建立专门保护制度已成为必然选择。... 中医药传统知识是中医药的核心内容,兼具卫生、经济、科技、文化、生态五重资源价值。目前中医药传统知识面临国外不当占有、盗用,国内传承、保护不力的双重困局,现行法律制度无法实现全面、系统保护,建立专门保护制度已成为必然选择。专门保护制度需要解决四个核心问题:对外防御侵占和不当占有,对内保护持有人权利并规范知识的获取与利用,化解持有人利益与社会公共利益之间的矛盾,处理与现行法律制度的衔接。在此基础上,提出构建中医药传统知识专门保护制度的四个机制,即阻却外国不当专利申请的防御机制、持有人权利保护机制、持有人利益与社会公共利益平衡机制、与现行法律制度的衔接机制,以更好促进中医药传统知识的保护、传承、创新、发展。 展开更多
关键词 中医药传统知识 专门保护 知识产权 利益平衡 持有人权利
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Analysis on Situation of Traditional Chinese Medicine Development and Protection Strategies in China 被引量:6
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作者 LIU Hui MA Zhi-guo 《Chinese Journal of Integrative Medicine》 SCIE CAS CSCD 2020年第12期943-946,共4页
With the worldwide growing interest and commercial value of traditional Chinese medicine(TCM)industries and products,the protection issue of TCM knowledge is increasingly concerned by Chinese government.Here,we invest... With the worldwide growing interest and commercial value of traditional Chinese medicine(TCM)industries and products,the protection issue of TCM knowledge is increasingly concerned by Chinese government.Here,we investigated the current situation and trend of TCM development and knowledge protection in China through accessing academic research tools including China National Knowledge Infrastructure(CNKI),Wanfang Data,VIP China Science and Technology Journal Database(VIP)and Google Scholar,analyzing the latest data released by National Administration of Traditional Chinese Medicine,China Statistical Yearbook of Chinese Medicine and China Statistical Yearbook.Our results demonstrate that current administration in China is continuing to support TCM development by increasing investment and expanding the scale in TCM research and administration.The increasing attention of Chinese scholars and government has led to laws and regulations issued more densely to strengthen TCM knowledge protection and promote fair use and fast development. 展开更多
关键词 traditional chinese medicine integrative medicine POLICY protection strategies DEVELOPMENT
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馆藏优秀传统文化资源再生性保护与价值释放——基于中医药古籍的调查分析
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作者 崔海英 《档案管理》 北大核心 2024年第2期110-115,共6页
通过调查统计河南省各类图书馆、文博单位等中医药古籍资源存藏、保护、整理和利用情况,分析河南省中医药古籍资源馆藏开发整理存在的问题,提出“加强中医药古籍保护与利用工作的领导与统筹”“深入挖掘整理河南省中医药古籍资源”“确... 通过调查统计河南省各类图书馆、文博单位等中医药古籍资源存藏、保护、整理和利用情况,分析河南省中医药古籍资源馆藏开发整理存在的问题,提出“加强中医药古籍保护与利用工作的领导与统筹”“深入挖掘整理河南省中医药古籍资源”“确定重点保护对象,推进中医药古籍多层级保护”“加大中医药古籍保护领域复合型人才培养力度”“加强中医药古籍艺术与文化价值的发掘与传播”等推动河南省中医药发展的举措。 展开更多
关键词 传统文化 馆藏资源 中医药古籍 古籍整理 古籍保护 古籍利用 再生性保护 价值增值
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现代化中医药专利保护的制度困境与出路--基于对中医药特点与专利保护适应性的反思
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作者 马一德 汪婷 《科技与法律(中英文)》 2024年第4期1-10,共10页
符合西医药特点的专利保护制度在中医药现代化进程中难以适应。尽管现行专利制度已对涉及中药领域发明专利申请审查的特殊情形作出了具体规定,但在本土语境下据此保护主要根植于我国传统知识领域的中医药发明创造时,中医药的复杂性、整... 符合西医药特点的专利保护制度在中医药现代化进程中难以适应。尽管现行专利制度已对涉及中药领域发明专利申请审查的特殊情形作出了具体规定,但在本土语境下据此保护主要根植于我国传统知识领域的中医药发明创造时,中医药的复杂性、整体性、道地性和时节性、差异性等特点仍未得到充分体现,并由此产生中医相关发明创造不具有专利适格性、专利审查缺乏一般性指导规则、申请文件难以通过合规性审查、申请主题的可专利性要求过高、关键性概念缺乏细化指导规则等问题。为此,可从专门审查标准的制定和商业秘密的补充保护两方面出发,寻求前述问题的具体解决方案,以应对中医药专利保护的适应性需求,从而完善中医药知识产权保护体系。 展开更多
关键词 中医药 专利 适应性 专门制度 商业秘密 补充保护
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朱熹家族史事考——以婺源《韩溪程氏梅山支谱》所见朱槔佚信为中心
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作者 黄太勇 《福建史志》 2024年第2期56-63,共8页
今上海图书馆藏婺源《韩溪程氏梅山支谱》中发现朱槔佚信三通,是朱槔随朱熹家族从婺源迁居福建后写给婺源表弟程鼎的,其中较为详细地反映出朱熹家族入闽初期的生活状况、学术转向以及与婺源韩溪程氏家族的关系等史事,可以与其它相关记... 今上海图书馆藏婺源《韩溪程氏梅山支谱》中发现朱槔佚信三通,是朱槔随朱熹家族从婺源迁居福建后写给婺源表弟程鼎的,其中较为详细地反映出朱熹家族入闽初期的生活状况、学术转向以及与婺源韩溪程氏家族的关系等史事,可以与其它相关记载互补互证,对朱熹家族史的研究具有较高的史料价值。 展开更多
关键词 朱熹家族 《韩溪程氏梅山支谱》 朱槔
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中药渣在废水处理及土壤修复中的应用 被引量:1
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作者 阮晓玲 李翔 +1 位作者 邹青 王紫嫣 《湖南生态科学学报》 CAS 2024年第1期58-65,共8页
随着中草药的普及和医药行业的不断发展,我国每年都会产生大量的中药渣。这些中药渣主要来源于药用动植物。传统的中药渣处置方法有焚烧法、堆放法和埋填法。这些方法不仅造成中药渣的极大浪费,而且污染环境。因此,中药渣的有效处理成... 随着中草药的普及和医药行业的不断发展,我国每年都会产生大量的中药渣。这些中药渣主要来源于药用动植物。传统的中药渣处置方法有焚烧法、堆放法和埋填法。这些方法不仅造成中药渣的极大浪费,而且污染环境。因此,中药渣的有效处理成为我国制药企业亟待解决的问题。近年来,中药渣在废水处理、土壤修复中的应用价值引起了广泛关注。本文将对中药渣在去除废水中重金属、抗生素、亚甲蓝及其他离子,及在重金属污染土壤修复中的应用进行综述,并对中药渣再利用中存在的问题和今后的发展进行探讨,为中药渣的可持续利用提供新的方向。 展开更多
关键词 中药渣 环境保护 再利用 污水处理 土壤污染修复
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基于文化自信视角探究中医药传统知识保护
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作者 宋昱佼 国华 +5 位作者 刘谦 秦培洁 安宏 朱婷钰 张凤霞 刘剑锋 《中国医药导报》 CAS 2024年第17期124-126,139,共4页
中医药传统知识是中华优秀传统文化的载体,是坚定中医文化自信的牢固根基。当前国际形势和现实国情错综复杂,基于我国的现实国情和党情,根据中医药传统知识被国内外不当占有使用、失传或国人不理解等情况,医药工作者应坚定中医药文化自... 中医药传统知识是中华优秀传统文化的载体,是坚定中医文化自信的牢固根基。当前国际形势和现实国情错综复杂,基于我国的现实国情和党情,根据中医药传统知识被国内外不当占有使用、失传或国人不理解等情况,医药工作者应坚定中医药文化自信,通过提高人民群众传承中医药传统知识的积极性,同时通过完善法律及行政等手段,保护继承发展好中医药传统知识,激发中医药文化的现代活力,提高中医药临床服务能力,为建设社会主义文化强国,实现中华民族伟大复兴作出贡献。 展开更多
关键词 文化自信 中医药传统知识保护 文化强国
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山东海岸单叶蔓荆现状分析及保护对策
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作者 刘芳瑞 胡晶红 +3 位作者 刘谦 刘茜 张赫 付先军 《山东中医药大学学报》 2024年第2期135-139,共5页
单叶蔓荆是蔓荆子药材的来源,也是重要的野生海岸保护植被,是聚社会、生态、药用价值于一体的重要资源。鉴于目前单叶蔓荆资源受到严重破坏实情,以第四次全国中药资源普查数据为基础,结合实地调研,对山东省单叶蔓荆资源分布情况和资源... 单叶蔓荆是蔓荆子药材的来源,也是重要的野生海岸保护植被,是聚社会、生态、药用价值于一体的重要资源。鉴于目前单叶蔓荆资源受到严重破坏实情,以第四次全国中药资源普查数据为基础,结合实地调研,对山东省单叶蔓荆资源分布情况和资源特点进行分析,并针对目前单叶蔓荆资源栖息地受损严重、种质资源单一、市场效益欠佳等主要问题,提出建立保护基地、选育新品种、多用途开发等多条针对性对策建议,旨在为沿海沙质海岸单叶蔓荆种源的保护和发展利用提供客观依据。 展开更多
关键词 海洋中药 单叶蔓荆 资源清查 种质资源 市场效益 建立保护基地 选育新品种
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某三级甲等中医院医务人员职业暴露现状分析
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作者 蒋东贤 蓝志明 +1 位作者 谢懿 郭竹英 《中国医疗管理科学》 2024年第5期77-81,共5页
目的了解中医院医务人员职业暴露现状和特征,为制订有效的职业安全防护策略提供参考。方法采用回顾性分析方法,对广东省某三级甲等中医院2020年1月至2023年12月发生职业暴露的医务人员资料进行分析。结果2020年—2023年该医院共发生职... 目的了解中医院医务人员职业暴露现状和特征,为制订有效的职业安全防护策略提供参考。方法采用回顾性分析方法,对广东省某三级甲等中医院2020年1月至2023年12月发生职业暴露的医务人员资料进行分析。结果2020年—2023年该医院共发生职业暴露事件398例,发生率为4.83%。不同年份职业暴露发生率比较,差异无统计学意义(P>0.05)。发生职业暴露的人群中,女性、工龄≤5年者及医生占比较高。暴露发生环节主要是拆卸器械或设备(40.70%),发生场所以病房为主(56.28%),暴露方式以锐器伤为主(87.69%),种类以针灸针最为常见(42.69%)。暴露源多见于无血源性传染疾病(51.26%)。暴露时有185人(46.48%)佩戴手套,376人(94.47%)进行符合要求的紧急应急处理。暴露后经6个月随访监测,均未发生暴露后感染。结论中医院医务人员职业暴露发生率较高,应加强规范安全注射和职业安全培训,增强职业防护意识,进一步预防职业暴露发生。 展开更多
关键词 中医院 医务人员 职业暴露 职业防护
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中药降糖机制研究进展
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作者 温志歌 张珊 倪青 《世界中医药》 CAS 北大核心 2024年第4期594-599,共6页
糖尿病(DM)是由于胰岛素缺乏导致血液葡萄糖升高的代谢性疾病。胰岛素抵抗(IR)导致胰岛素分泌相对不足和利用障碍;胰岛B细胞功能下降,导致胰岛素分泌绝对不足,导致血糖蓄积。中药降糖临床疗效确切,作用机制有待阐明。中药可能通过多途... 糖尿病(DM)是由于胰岛素缺乏导致血液葡萄糖升高的代谢性疾病。胰岛素抵抗(IR)导致胰岛素分泌相对不足和利用障碍;胰岛B细胞功能下降,导致胰岛素分泌绝对不足,导致血糖蓄积。中药降糖临床疗效确切,作用机制有待阐明。中药可能通过多途径、多靶点改善IR、保护胰岛B细胞功能,从而改善糖脂代谢,治疗糖尿病。本文基于近10年中药(中药活性成分、单味药、复方)降糖的研究型文献,围绕中药从抗氧化应激、抗炎、调控葡萄糖转运通路、调节肠道菌群、抑制异位脂沉积、抑制脂肪组织巨噬细胞外泌体改善IR,刺激胰岛素分泌、调控胰岛B细胞分化、损伤、凋亡、再生以保护胰岛B细胞功能2大方面,系统梳理、归纳总结中药潜在降糖机制,并立足当前中药降糖研究领域,分析目前存在问题,探索未来发展趋势和方向,为进一步探索中药治疗DM基础研究提供参考。 展开更多
关键词 中药 降糖 作用机制 胰岛素抵抗 胰岛B细胞 保护 分化 中医理论
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广西“桂十味”药材体外抗氧化活性及保护作用
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作者 张兵 陈聪 +3 位作者 彭彦芬 韦坤华 余启明 谭相端 《华夏医学》 CAS 2024年第4期9-19,共11页
目的探讨广西“桂十味”药材不同溶剂提取物体外抗氧化活性及对H_(2)O_(2)诱导HepG2和L02细胞氧化损伤的保护作用。方法以广西“桂十味”各味药材为原料,利用水和75%乙醇制备不同溶剂提取物,通过DPPH、ABTS自由基清除法和Fe^(3+)还原能... 目的探讨广西“桂十味”药材不同溶剂提取物体外抗氧化活性及对H_(2)O_(2)诱导HepG2和L02细胞氧化损伤的保护作用。方法以广西“桂十味”各味药材为原料,利用水和75%乙醇制备不同溶剂提取物,通过DPPH、ABTS自由基清除法和Fe^(3+)还原能力法评价其抗氧化活性,采用MTT法评价提取物对H_(2)O_(2)诱导细胞氧化损伤的保护作用。结果鸡血藤水提取物表现出最强的DPPH和ABTS自由基清除能力,鸡血藤75%乙醇提取物表现出最强的Fe^(3+)还原能力;山豆根水提取物及鸡血藤75%乙醇提取物对H_(2)O_(2)诱导HepG2细胞氧化损伤的保护作用最强;鸡骨草水提取物及龙眼肉、莪术75%乙醇提取物对H_(2)O_(2)诱导L02细胞氧化损伤的保护作用最强。结论通过比较“桂十味”各味药材不同溶剂提取物的抗氧化活性及对H_(2)O_(2)诱导细胞氧化损伤的保护作用,可为后期“桂十味”道地药材的抗氧化研发提供实验基础。 展开更多
关键词 桂十味 不同溶剂提取物 抗氧化活性 抗细胞氧化损伤
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