Pseudoainhum Associated With Lepromatous Leprosy:A Very Rare Association in Modern World

Introduction:Pseudoainhum(dactylolysis spontanea)is characterized by the development of a fibrous band around the digit that gradually leads to autoamputation.Digital pain associated with Pseudoainhum may not be evident in patients with neuropathic conditions.Here,we present a rare case of pseudoainhum patient,which describes a very rare association of pseudoainhum with leprosy.Case presentation:A 48 year old male with lepromatous leprosy,with resorption of digits,charcot joints and tropical ulcers was seen in the clinic.The forth digit of the left hand had a narrowing due to a fibrous band at the 2nd inter phalangeal joint with shiny tethering distal phalanx.He could not recall the duration of the ainhum.He was not suffering from any pain.Discussion:The current report describes a very rare association of pseudoainhum with leprosy.The case involved a 48-year-old man in the dermatology ward with lepromatous leprosy presenting with a pseudoainhum.Conclusion:This case highlights the possibility of delayed presentation of patients with pseudoainhum to physicians when the patients have underlying neuropathic conditions that prevent feeling finger pain and cause abnormal appearance of the digits,especially in leprosy.

汗孔角化症合并假性阿洪病1例

报告1例汗孔角化症合并假性阿洪病病例。患者女,16岁。自2岁起,左手背出现褐色角化性丘疹,并逐渐蔓延至左上肢及左手示指及中指,临床症状及组织病理改变符合汗孔角化症。5年前左手中指第一指关节屈侧横沟出现线形缩窄。

扁平苔藓致假性阿洪病

报告1例扁平苔藓致假性阿洪病。患者女,25岁。因手部皮疹伴指(趾)甲脱落,左手拇指变细20年就诊。皮损组织病理检查:角化过度伴角化不全,颗粒层楔形增厚,真皮浅层单个核细胞苔藓样浸润。诊断:扁平苔藓致假性阿洪病。

弥漫性掌跖角化症并发假性阿洪病一例

43岁女性患者,双手角化过度30年、指间关节环形缩窄10年,跖部角化过度10年。皮肤科情况:双手皮肤角化过度,表面可见片状红斑伴脱屑,示指、中指和小指的指间关节变细呈环状缩窄。红斑组织病理示:致密的角化过度,表皮不规则增生,真皮浅层血管扩张,周围有稀疏淋巴细胞浸润。双手X线检查骨质、关节间隙、关节面及软组织均无异常。诊断:弥漫性掌跖角化症并发假性阿洪病。

Kindler型大疱性表皮松解症合并假性阿洪病1例

患者女,26岁,出生后四肢皮肤反复出现水疱,后逐渐减轻,2岁后出现光敏感、皮肤萎缩、色素异常,10岁后逐渐出现掌跖角化过度及双手小指假性阿洪现象。基因检测:FERMT1基因检出一新发现纯合变异:c.1861-1G>A,导致氨基酸发生剪接突变,患者父母均为该变异杂合携带者。诊断:Kindler型大疱性表皮松解症合并假性阿洪病。