Correlation between psychological factors and the expression of galanin and 5‑hydroxytryptamine in different subtypes of gastroesophageal reflux disease

Objective:The aim of this study is to analyze the differences in galanin(GAL)and 5‑hydroxytryptamine(5‑HT)levels in patients with different subtypes of gastroesophageal reflux disease(GERD)and its correlation with anxiety and depression in patients.Methods:Using the reflux disease questionnaire,238 patients with GERD were selected as the study group.According to the endoscopic performance,they were divided into the nonerosive reflux disease(NERD)group(114 patients)and the RE group(124 patients).Sixty healthy people were selected as the control group.All research subjects were tested using the self‑rating anxiety scale(SAS)and the self‑rating depression scale(SDS)to assess the severity of anxiety and depression.The levels of 5‑HT and GAL were analyzed using enzyme‑linked immunosorbent assay.Results:Compared with the control group,5‑HT level in GERD patients without anxiety and depression was higher(t=1.97,P<0.05)and GAL level was lower(t=1.97,P<0.05).NERD patients demonstrated more server anxiety(F=55.92,P<0.05)and depression problems(F=36.51,P<0.05)compared to reflux esophagitis(RE)patients.The 5‑HT level was lower(F=54.53,P<0.05)and the GAL level was higher(F=8.00,P<0.05)in NERD patients compared with the control group.Furthermore,5‑HT level was negatively correlated with SAS(r=−0.789,P<0.05)and SDS(r=−0.787,P<0.05)scores;GAL level was positively correlated with SAS(r=0.688,P<0.05)and SDS(r=0.705,P<0.05)scores;5‑HT and GAL level were negatively correlated(r=−0.744,P<0.05).Conclusions:5‑HT level is higher and GAL level was lower in GERD patients without anxiety and depression than healthy people;the symptoms of anxiety and depression of NERD patients are more severe compared to those of RE patients;the severity of anxiety and depression was negatively correlated with the level of 5‑HT and positively with GAL level.

Psychological Influence Factors Analysis of the New Generation Employees’ Moral Choices from the Perspective of Cognitive Neurology

At present,the academic researches on moral choices focus mainly on the individuals’external behaviors,without fully considering the influences of the individuals’internal psychological factors.Based on the model of complete information static games in the Non-cooperative Game theory,the present research has designed a“Red and Blue Experiment”to explore the psychological influencing factors of the new generation employees’moral choices.The research has conducted psychoanalysis on the new generation employees through experiments and interviews with 118 data sources,and concluded the characteristics in relation to the different stages of psychological processes and moral choices of the experimental population.Through comparative analysis,it is found that:the psychological factors,such as trust,doubt,and guilt will influence the new generation employees’moral choices,guiding them to make choices,such as risk aversion and mutual benefit and win-win,in the process.Additionally,the research has also provided effective scientific evidence for the new generation employees’mental health development and career planning.

Evaluation of factors affecting psychological morbidity in emergency medicine practitioners

BACKGROUND: Assessing and evaluating mental health status can provide educational planners valuable information to predict the quality of physicians' performance at work. These data can help physicians to practice in the most desired way. The study aimed to evaluate factors affecting psychological morbidity in Iranian emergency medicine practitioners at educational hospitals of Tehran.METHODS: In this cross sectional study 204 participants(emergency medicine residents and specialists) from educational hospitals of Tehran were recruited and their psychological morbidity was assessed by using a 28-question Goldberg General Health Questionnaire(GHQ-28). Somatization, anxiety and sleep disorders, social dysfunction and depression were evaluated among practitioners and compared to demographic and job related variables.RESULTS: Two hundreds and four participants consisting of 146(71.6%) males and 58(28.4%) females were evaluated. Of all participants, 55(27%) were single and 149(73%) were married. Most of our participants(40.2%) were between 30–35 years old. By using GHQ-28, 129(63.2%) were recognized as normal and 75(36.8%) suffered some mental health disorders. There was a signifi cant gender difference between normal practitioners and practitioners with disorder(P=0.02) while marital status had no significant difference(P=0.2). Only 19(9.3%) declared having some major mental health issue in the previous month.CONCLUSION: Females encountered more mental health disorders than male(P=0.02) and the most common disorder observed was somatization(P=0.006).

Review: Psychological Problems of Pregnant Women and Progress of Psychological Guidance in Recurrent Miscarriage

In order to understand the psychological problems of pregnant women, this article explores the psychological problems and the sources of psychological stress of pregnant women who have a history of recurrent miscarriage after pregnancy. The analysis shows that the psychological stress of pregnant women may be one of the reasons for recurrent miscarriage. Strengthening mental health education during pregnancy can avoid the stimulation of bad emotions and environment, prevent the spontaneous abortion caused by psychological reasons, and improve the quality of pregnancy. It is particularly important to grasp the mental state of pregnant women with recurrent abortion timely and carry out corresponding psychological counseling and psychological nursing.

Behavioral gastroenterology: An emerging system and new frontier of action

Behavioral gastroenterology is a new interdisciplinary science that explores the influence of unhealthy lifestyles and psychological factors on the digestive system and addresses the prevention,diagnosis,treatment,and rehabilitation of digestive diseases. Moreover,the concept of whole-course intervention with a focus on disease prevention and a new model of integrated therapy based on alterations of lifestyle and psychology are being gradually established. This paradigm may substantively impact the prevention and treatment of digestive diseases.

Effectiveness of cognitive behavioral therapy-based interventions on health outcomes in patients with coronary heart disease:A metaanalysis

BACKGROUND Recently,the efficacy of cognitive behavioral therapy(CBT)-based intervention on health outcomes in patients with coronary heart disease(CHD)has been recognized in randomized controlled trials(RCTs),but no comprehensive systematic review has been conducted.To address this research gap,our study aimed to evaluate whether comprehensive CBT-based interventions positively affect health outcomes in CHD patients.It was hypothesized that CBT-based interventions are effective in:(1)Reducing depression,anxiety,and stress symptoms;(2)Reducing body mass index,blood pressure,and lipid levels;and(3)Improving quality of life,and exercise endurance.AIM To verify the effectiveness of CBT-based interventions on CHD patients through a meta-analysis of previous publications.METHODS Relevant RCTs published in English were obtained by searching electronic databases,including PubMed,Embase,Cochrane Central Register of Controlled Trials,Scopus,and Proquest,with the retrieval time from inception to August 2020.The primary outcomes were psychological factors(depression,anxiety,and stress symptoms),physiological factors(body mass index,blood pressure,blood lipids).The secondary outcomes included quality of life and exercise endurance.We used Review Manager 5.3 to conduct the meta-analysis and used the Physiotherapy Evidence Database tool to evaluate the quality of studies.RESULTS A total of 22 RCTs comprising 4991 patients with CHD were included in the systematic review and meta-analysis.The main analysis revealed that CBT-based intervention can reduce depression symptoms:-2.00[95%confidence interval(CI):-2.83 to-1.16,P<0.001];anxiety symptoms:-2.07(95%CI:-3.39 to-0.75,P=0.002);stress symptoms:-3.33(95%CI:-4.23 to-2.44,P<0.001);body mass index:-0.47(95%CI:-0.81 to-0.13,P=0.006);and improve physical functioning:3.36(95%CI:1.63 to 5.10,P=0.000)and mental functioning:6.91(95%CI:4.10 to 9.73,P<0.001).Moreover,subgroup analysis results showed that CBT-based interventions were more effective for symptoms of depression and anxiety in CHD patients when individual,as opposed to group treatment,and psycho-education,behavioral and cognitive strategies were applied as the core treatment approaches.CONCLUSION CBT-based interventions are effective treatment strategies for CHD patients,significantly improving their symptoms of depression,anxiety and stress,body mass index,and health-related quality of life.

Prediction Models for COVID-19 Integrating Age Groups, Gender, and Underlying Conditions

The COVID-19 pandemic has caused hundreds of thousands of deaths,millions of infections worldwide,and the loss of trillions of dollars for many large economies.It poses a grave threat to the human population with an excessive number of patients constituting an unprecedented challenge with which health systems have to cope.Researchers from many domains have devised diverse approaches for the timely diagnosis of COVID-19 to facilitate medical responses.In the same vein,a wide variety of research studies have investigated underlying medical conditions for indicators suggesting the severity and mortality of,and role of age groups and gender on,the probability of COVID-19 infection.This study aimed to review,analyze,and critically appraise published works that report on various factors to explain their relationship with COVID-19.Such studies span a wide range,including descriptive analyses,ratio analyses,cohort,prospective and retrospective studies.Various studies that describe indicators to determine the probability of infection among the general population,as well as the risk factors associated with severe illness and mortality,are critically analyzed and these ndings are discussed in detail.A comprehensive analysis was conducted on research studies that investigated the perceived differences in vulnerability of different age groups and genders to severe outcomes of COVID-19.Studies incorporating important demographic,health,and socioeconomic characteristics are highlighted to emphasize their importance.Predominantly,the lack of an appropriated dataset that contains demographic,personal health,and socioeconomic information implicates the efcacy and efciency of the discussed methods.Results are overstated on the part of both exclusion of quarantined and patients with mild symptoms and inclusion of the data from hospitals where the majority of the cases are potentially ill.

Investigation and analysis of network psychology of college students

Based on basic situational research and analysis carried out on 638 college students using network, we found that as many as 20 percent of the students are not only largely dependent on internet, but also addicted to it. Further biography characteristics analyses for different individuals on the four dimensions of the network forced addiction, tolerance, and time management and interpersonal relationship and health, show that there are significant differences in grades, gender with different education levels of their parents. Further researches on discrepancy that addicted groups have in network entertainment addiction, network information, cyber porn, network relations and network transactions addictions also illustrate that significant discrepancies exist in gender, net age, different discipline and other factors. Finally we put forward some correlative measures to solve the problems of college students network psychology from individuals, schools, and society levels.

Fatigue Analysis and Evaluation Method of Ergonomic Virtual Human

The ergonomic digital design and evaluation of man-machine system is the main application fields of virtual human technology. Because of the complexity of physical person and uncertainty of fatigue generation mechanism, it is difficult to express a nd evaluate the Virtual Human's fatigue state. This paper summarizes the characteristics of virtual human's fatigue evaluation, such as undeterminable, invisible, the constraint conditions can been used. Viewed from the strengths and weaknesses of preexisting models, metabolic energy expenditure model, dynamic muscle fatigue model and a model to assess fatigue at joint-level using the half-joint concept, this paper puts forward the future development trend that the combination of subjective and objective,diversificationoftheanalyzablemotion,real-timeandvisualexpression.

A mini-review on how the COVID-19 pandemic affected intertemporal choice

The coronavirus disease(COVID-19)has extremely harmful effects on individual lifestyles,and at present,people must make financial or survival decisions under the profound changes frequently.Although it has been reported that COVID-19 changed decision-making patterns,the underlying mechanisms remained unclear.This mini-review focuses on the impact of the COVID-19 pandemic on in-tertemporal choice,and potential psychological,biological,and social factors that mediate this relationship.A search of the Web of Science electronic database yielded 23 studies.The results showed that under the COVID-19 pandemic,people tended to choose immediate and smaller rewards,and became less patient.In particular,people with negative emotions,in a worse condition of physical health,or who did not comply with their government restriction rules tended to become more"short-sighted"in behavioral terms.Future studies should examine more longitudinal and cross-cultural research to give a broad view about the decision-making change under the COVID-19 pandemic.