During the test on transient pressure signal in explosion field,false trigger caused by field interference can lead to test failure.To improve the stability of test system,a signal detection and recognition technology...During the test on transient pressure signal in explosion field,false trigger caused by field interference can lead to test failure.To improve the stability of test system,a signal detection and recognition technology is proposed for transient pressure test system.In the process of signal acquisition,firstly,electrical levels are monitored in real time to find effective abrupt changes and mark them;then the effective data segments are detecdted totected;thus the effective signals can be acquired in turn finally.The experimental results show that the shock wave signal can be collected effectively and the reliability of the test system can be improved after removal of interferences.展开更多
For the shock wave overpressure signal measurement of explosion field, the type and equivalent of the ammunition as well as the distance from test nodes to ground zero have a great influence on the characteristics of ...For the shock wave overpressure signal measurement of explosion field, the type and equivalent of the ammunition as well as the distance from test nodes to ground zero have a great influence on the characteristics of shock wave signal. To ensure that shock wave signal with different characteristic parameters can be collected completely in the test of shooting range, a tran- sient pressure signal storage system with configurable parameters is presented. In order to meet the requirements of different test nodes, the system can set parameters of all test nodes by wireless communication in explosion field. The feasibility and re- liability of the system are fully verified through transient pressure measurement in explosion field.展开更多
Aiming at harsh environment of cluster bombs center tube explosion dispersion and difficulties in installation of traditional test systems,a storage test system based on 16-bit ultra-low power microcontroller MSP430 i...Aiming at harsh environment of cluster bombs center tube explosion dispersion and difficulties in installation of traditional test systems,a storage test system based on 16-bit ultra-low power microcontroller MSP430 is designed in order to acquire gas pressure during cluster bombs dispersion.To meet the requirement of low power consumption,the working states of system's modules during data acquisition are elaborated and the equation to calculate the gas pressure change during cylindrical center tube opening the hatch is deduced.The field test is conducted and good test results are obtained.展开更多
BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their occurrence.AIM To investigate whether coronary spasms can be predicted using changes i...BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their occurrence.AIM To investigate whether coronary spasms can be predicted using changes in intracoronary artery pressure measured using a pressure wire during the SPT.METHODS Seventy patients underwent SPTs with pressure-wire measurement of intracoronary artery pressure.During each SPT,the pressure wire was advanced into the distal portion of the right coronary artery(RCA)and left anterior descending coronary artery,and the ratio of intracoronary pressure to aortic pressure(Pd/Pa)was monitored.Coronary spasm was defined as an arterial narrowing of>90%in response to the administration of acetylcholine(ACh),with chest symptoms and/or ischemic electrocardiographic changes.ACh was administered to the RCA at low,moderate,or high doses of 20,50,or 80μg,respectively,and to the left coronary artery(LCA)at low,moderate,or high doses of 50,100,or 200μg,respectively.Coronary arteries with coronary spasms at low doses of ACh were defined as group L,and those with coronary spasms at moderate or high doses were defined as group MH.Those who did not occur coronary spasms at any ACh dose were designated as group N.RESULTS Among the 132 coronary arteries assessed using a pressure wire,there were 49 in group N,25 in group L,and 58 in group MH.Baseline Pd/Pa was the lowest in group L(P=0.001).The decrease in the Pd/Pa between baseline to low doses of ACh was lower in group MH than in group N(P<0.001).A receiver-operating characteristics analysis showed that the cutoff baseline Pd/Pa value for predicting group L was 0.95,with a sensitivity of 0.600(15/25)and a specificity of 0.713(76/107)and that the cutoff value of Pd/Pa from baseline to low doses of ACh for predicting group MH was−0.04,with a sensitivity of 0.741(43/58)and a specificity of 0.694(34/49).CONCLUSION These findings suggest that indices of intracoronary pressure during SPT may be useful means for predicting the occurrence of coronary spasms.展开更多
Background and Aims: Pulse pressure variation (PPV) is a reliable and predictive dynamic parameter presently being utilized for fluid responsiveness. In the operating room, fluid administration based on PPV monitoring...Background and Aims: Pulse pressure variation (PPV) is a reliable and predictive dynamic parameter presently being utilized for fluid responsiveness. In the operating room, fluid administration based on PPV monitoring helps the physician in deciding whether to volume resuscitate or use interventions in patients undergoing surgery. Propofol is an intravenous induction agent which lowers blood pressure. There are multiple causes such as depression in cardiac output, and peripheral vasodilatation for hypotension. We undertook this study to observe the utility of PPV as a guide to fluid therapy after propofol induction. Primary outcome of our study was to monitor PPV as a marker of fluid responsiveness for the hypotension caused by propofol induction. Secondary outcome included the correlation of PPV with other hemodynamic parameters like heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP);after induction with propofol at regular interval of time. Methods: A total number of 90 patients were recruited. Either of the radial artery was then cannulated under local anaesthesia with 20G VygonLeadercath arterial cannula and invasive monitoring transduced. A baseline recording of heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and PPV was then recorded. Patients were then induced with predetermined doses of propofol (2 mg/kg) and recordings of HR, SBP, DBP, and PPV were taken at 5, 10 and 15 minutes. Results: Intraoperatively, PPV was significantly higher at 5 minutes and significantly lower at 15 minutes after induction. It was observed that there were no statistically significant correlations between PPV and SBP or DBP. PPV was strongly and directly associated with HR. Conclusion: We were able to establish that PPV predicts fluid responsiveness in hypotension caused by propofol induction;and can be used to administer fluid therapy in managing such hypotension. However, PPV was not directly correlated with hypotension subsequent to propofol administration.展开更多
Reliability of medical devices such as infusion pumps is extremely important because these devices are being used in patients who are in critical condition. Occlusion pressure, as an important parameter of infusion pu...Reliability of medical devices such as infusion pumps is extremely important because these devices are being used in patients who are in critical condition. Occlusion pressure, as an important parameter of infusion pumps, should be detected when an occlusion occurred. How-ever, infusion pumps’ occlusion pressure could not be tested and the performance of these pumps is not known to us. In order to test the occlusion pressure of infusion pump, a testing system has been put forward according to standards of IEC 60601-2-24:1998/ GB 9706.27- 2005. The system is comprised of sensor, acquisition card, three-way tap and so on;this system is controlled by a PC. At the same time, sampling rate could be changed if necessary and test time could be recorded. And then the characteristics of this system were studied, such as linear, effects of pump rates and different pumps. The system remained linear in a given environment. The higher is the pump rate, the faster is the time to reach occlusion condi-tion. The testing system has been proved to be effective in testing the occlusion pressure of infusion pumps and the accuracy error of pressure is content the demand of ±1% of range.展开更多
It remains challenging to effectively estimate the remaining capacity of the secondary lithium-ion batteries that have been widely adopted for consumer electronics,energy storage,and electric vehicles.Herein,by integr...It remains challenging to effectively estimate the remaining capacity of the secondary lithium-ion batteries that have been widely adopted for consumer electronics,energy storage,and electric vehicles.Herein,by integrating regular real-time current short pulse tests with data-driven Gaussian process regression algorithm,an efficient battery estimation has been successfully developed and validated for batteries with capacity ranging from 100%of the state of health(SOH)to below 50%,reaching an average accuracy as high as 95%.Interestingly,the proposed pulse test strategy for battery capacity measurement could reduce test time by more than 80%compared with regular long charge/discharge tests.The short-term features of the current pulse test were selected for an optimal training process.Data at different voltage stages and state of charge(SOC)are collected and explored to find the most suitable estimation model.In particular,we explore the validity of five different machine-learning methods for estimating capacity driven by pulse features,whereas Gaussian process regression with Matern kernel performs the best,providing guidance for future exploration.The new strategy of combining short pulse tests with machine-learning algorithms could further open window for efficiently forecasting lithium-ion battery remaining capacity.展开更多
Recent developments in brain magnetic resonance imaging using advanced Susceptibility Weighted Imaging (SWI) have significantly increased the detection and prevalence of Cerebral Microbleeds (CMBs). Here, we aimed to ...Recent developments in brain magnetic resonance imaging using advanced Susceptibility Weighted Imaging (SWI) have significantly increased the detection and prevalence of Cerebral Microbleeds (CMBs). Here, we aimed to explore the association between Pulse Pressure (PP) and CMBs. Having been implicated in various arteriopathies, we hypothesized that elevated PP could also be a risk for CMBs. A retrospective case-control study was conducted from August 2021 to September 2022 at Zhongnan Hospital of Wuhan University China. Extracted data were analyzed in SPSS. Chi-square test, binary logistic regression, and Spearman’s correlation analysis were conducted.104 patients were analyzed. Univariate analysis showed no significant association between PP and CMBs, OR 1.65 (95% CI: 0.737 - 3.694;p > 0.05), while DBP and alcohol consumption were significant, ORs 2.956 (95% CI: 1.249 - 6.997, p < 0.05) and 2.525 (95% CI: 1.062 - 6.002, p < 0.05) respectively. Multivariate analysis, showed that PP was significantly associated with CMBs, OR 3.194 (95% CI: 1.024 - 9.964, p < 0.05) in combination with SBP, DBP, gender, age, smoking and alcohol consumption. Taken together, the study showed that elevated PP is associated with CMB, but is not an independent risk factor for CMBs.展开更多
Boom clay formation is a potential natural host rock for geological disposal of high-level nuclear waste in Belgium.Heating pulse tests with controlled power supply(maximum temperature was limited to 85℃) and contr...Boom clay formation is a potential natural host rock for geological disposal of high-level nuclear waste in Belgium.Heating pulse tests with controlled power supply(maximum temperature was limited to 85℃) and controlled hydraulic boundary conditions were performed under nearly constant volume conditions to study the impact of thermal loading on the clay formation.Selected test results of intact borehole samples retrieved in horizontal direction are presented and discussed.The study focuses on the time evolution of temperature and pore water pressure changes along heating and cooling paths,i.e.pore pressure build-up during quasi-undrained heating and later dissipation at constant temperature.展开更多
Dielectric barrier discharge (DBD) excitated by pulsed power is a promising method for producing nonthermal plasma at atmospheric pressure. Discharge characteristic in a DBD with salt water as electrodes by a home-m...Dielectric barrier discharge (DBD) excitated by pulsed power is a promising method for producing nonthermal plasma at atmospheric pressure. Discharge characteristic in a DBD with salt water as electrodes by a home-made unipolar nanosecond-pulse power source is presented in this paper. The generator is capable of providing repetitive pulses with the voltage up to 30 kV and duration of 70 ns at a 300 Ω resistive load. Applied voltage and discharge current are measured under various experimental conditions. The DBD created between two liquid electrodes shows that the discharge is homogeneous and diffuse in the whole discharge regime, Spectra diagnosis is conducted by an optical emission spectroscopy. The air plasma has strong emission from nitrogen species below 400 nm, notably the nitrogen second positive system.展开更多
AIM:To compare the intraocular pressure(IOP)peaks and fluctuations using water drinking tests(WDTs)and mean diurnal IOP among Filipino patients with normal eyes and glaucoma suspectsMETHODS:This prospective study incl...AIM:To compare the intraocular pressure(IOP)peaks and fluctuations using water drinking tests(WDTs)and mean diurnal IOP among Filipino patients with normal eyes and glaucoma suspectsMETHODS:This prospective study included normal and glaucoma suspect patients.Each patient underwent both WDT and mean diurnal examination on separate visits.For mean diurnal examination,IOP was recorded every 2 h for 8 h while in WDT,IOP was recorded prior to WDT,and postWDT at 5,15,30,45,and 60 min.IOP peak was recorded as the highest IOP for both methods,and IOP fluctuation was recorded as highest IOP minus lowest IOP.RESULTS:With the comparison of diagnostic tests,both normal eyes and glaucoma suspect groups,the peak IOP was caught at 15 min.Comparative analysis of both groups also showed that the peak IOP measurements were statistically higher for the WDT compared to mean diurnal IOP(P=0.039,P=0.048 under normal group and P=0.032 and P=0.031 under glaucoma suspect group).Similarly,the WDT had a statistically higher mean IOP fluctuation score than the mean diurnal IOP method in both groups(P=0.003,P=0.011 under normal group;P=0.002 and P=0.005 under glaucoma suspect group).CONCLUSION:This study shows that WDT is a comparable diagnostic exam in predicting IOP fluctuations than mean diurnal measurement.WDT is a promising diagnostic procedure for risk assessment in glaucoma.展开更多
Given the problem of the long time required for testing gas pressure, we propose a fast-test method in which we used a technique of fast borehole sealing and air replenishing. Based on the characteristics of gas emiss...Given the problem of the long time required for testing gas pressure, we propose a fast-test method in which we used a technique of fast borehole sealing and air replenishing. Based on the characteristics of gas emission from boreholes to be tested, we built a theoretical model for calculating parameters during the process of increasing natural pressure and aeration. Using this model, we investigated the effect of different aeration conditions on velocity of pressure tests. The result shows that: 1) aerating air into boreholes can speed up gas pressure tests and 2) the more similar the pressure of the aerated air to the original gas pressure, the smaller the gas volume absorbed by coal and the shorter the time needed in pressure test. A case study in the Lu’an mining area shows that the time needed for gas pressure test is only 4 h using our method of aeration and 29 h under conditions of increasing natural pressure, saving time by 86.2%. This case study also indicates that, by using the aeration method, only one hour is needed for gas pressure to reach a stable state, which breaks the record of the shortest time needed for gas pressure tests in China.展开更多
Based on the documentation of the invited paper and the subsequent discussion at a virtual conference,discoveries are indicated,which are summarized in the following paper for further evaluation on the topic of non-th...Based on the documentation of the invited paper and the subsequent discussion at a virtual conference,discoveries are indicated,which are summarized in the following paper for further evaluation on the topic of non-thermal forces using terms of extremely powerful components of Maxwell’s stress tensor at the interaction of CPA(chirped pulse amplification)laser pulses in the fusion plasmas of hydrogen with the isotope 11 of boron.This is caused by a recoil mechanism given by the Fresnel formulas of the suppression of the reflectivity of inhomogeneous plasma given by optical constants of the plasma properties.展开更多
Pulsed eddy current (PEC) non-destructive test- ing and evaluation (NDT&E) has been around for some time and it is still attracting extensive attention from researchers around the globe, which can be witnessed th...Pulsed eddy current (PEC) non-destructive test- ing and evaluation (NDT&E) has been around for some time and it is still attracting extensive attention from researchers around the globe, which can be witnessed through the reports reviewed in this paper. Thanks to its richness of spectral components, various applications of this technique have been proposed and reported in the lit- erature covering both structural integrity inspection and material characterization in various industrial sectors. To support its development and for better understanding of the phenomena around the transient induced eddy currents, attempts for its modelling both analytically and numeri- cally have been made by researchers around the world. This review is an attempt to capture the state-of-the-art development and applications of PEC, especially in the last 15 years and it is not intended to be exhaustive. Future challenges and opportunities for PEC NDT&E are also presented.展开更多
Owing to the characteristics of arc ion plating(AIP) technique, the structure and composition of TiAlN films can be tailored by controlling of various parameters such as compositions of target materials, N2 partial pr...Owing to the characteristics of arc ion plating(AIP) technique, the structure and composition of TiAlN films can be tailored by controlling of various parameters such as compositions of target materials, N2 partial pressure, substrate bias and so on. In this study, several titanium aluminum nitride films were deposited on 1Cr11Ni2W2MoV steel for compressor blade of areo-engine under different d.c pulse bias voltage and nitrogen partial pressure. The effects of substrate pulse bias and nitrogen partial pressure on the deposition rate, droplet formation, microstruture and elemental component of the films were investigated.展开更多
Dielectric barrier discharge (DBD) between two cylindrical glass containers with salt water generated by a nanosecond repetitively pulsed power generator is reported. The electrical parameters, luminous images and s...Dielectric barrier discharge (DBD) between two cylindrical glass containers with salt water generated by a nanosecond repetitively pulsed power generator is reported. The electrical parameters, luminous images and spectrum diagnosis are presented. It is shown that the DBD possesses a large discharge current and an intense optical emission from the nitrogen second positive system below 400 nm. The gas temperature remains very close to room temperature regardless of pulse polarity. Luminous photographs with a short exposure time down to 2 ns indicate that no filament is observed and the discharge is homogeneous.展开更多
AIM: To investigate the effects of body mass index (BMI) on intraocular pressure (IOP) and ocular pulse amplitude(OPA). METHODS: Totally 140 healthy individuals without any systemic diseases were included in the study...AIM: To investigate the effects of body mass index (BMI) on intraocular pressure (IOP) and ocular pulse amplitude(OPA). METHODS: Totally 140 healthy individuals without any systemic diseases were included in the study. BMI (kg/m2) was calculated for every individual. IOP and OPA were measured with Pascal Dynamic contour tonometer (DCT). Blood pressure was also measured along with the DCT. The patients were divided into three groups according to BMI as: Group1, BMI<25; Group2, 25≤BMI<30; Group3, BMI≥30. Mean values of IOP, OPA, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were used in statistical analysis.RESULTS: In Group1, the means of IOP, OPA, were 16.8±2.3mmHg, 2.7±0.7mmHg respectively; and SBP, DBP were 120.0±6.1mmHg, and 77.4±5.6mmHg respectively. In group2, the mean IOP, OPA, SBP, and DBP were found to be 16.6±2.1mmHg, 2.4±0.7mmHg, 121.7±5.3mmHg, and 79.5±4.9mmHg respectively. In group3, the mean IOP, OPA, SBP, and DBP were found to be 17.3±1.7mmHg, 2.1±0.7mmHg, 122.4±5.7mmHg, and 79.7±5.2mmHg respectively. There were no statistically significant difference between groups in terms of IOP, SBP and DBP, while OPA values were significantly lower in group3 (P=0.001). CONCLUSION: Decreased OPA values in individuals with higher BMI may indicate that subjects with higher BMI have lower choroidal perfusion and lower ocular blood flow.展开更多
In this work the effects of O_2 concentration on the pulsed dielectric barrier discharge in helium-oxygen mixture at atmospheric pressure have been numerically researched by using a one-dimensional fluid model in conj...In this work the effects of O_2 concentration on the pulsed dielectric barrier discharge in helium-oxygen mixture at atmospheric pressure have been numerically researched by using a one-dimensional fluid model in conjunction with the chosen key species and chemical reactions.The reliability of the used model has been examined by comparing the calculated discharge current with the reported experiments. The present work presents the following significant results. The dominative positive and negative particles are He_2~+ and O_2^-, respectively, the densities of the reactive oxygen species(ROS) get their maxima nearly at the central position of the gap, and the density of the ground state O is highest in the ROS. The increase of O_2 concentration results in increasingly weak discharge and the time lag of the ignition. For O_2 concentrations below 1.1%,the density of O is much higher than other species, the averaged dissipated power density presents an evident increase for small O_2 concentration and then the increase becomes weak. In particular,the total density of the reactive oxygen species reaches its maximums at the O_2 concentration of about 0.5%. This characteristic further convinces the experimental observation that the O_2 concentration of 0.5% is an optimal O_2/He ratio in the inactivation of bacteria and biomolecules when radiated by using the plasmas produced in a helium oxygen mixture.展开更多
Offshore drilling has attracted more attention than ever before due to the increasing worldwide energy demand especially in China. High cost, long drilling cycles, and low rate of penetration (ROP) represent critica...Offshore drilling has attracted more attention than ever before due to the increasing worldwide energy demand especially in China. High cost, long drilling cycles, and low rate of penetration (ROP) represent critical challenges for offshore drilling operations. The hydraulic pulse generator was specifically designed, based on China offshore drilling technologies and parameters, to overcome problems encountered during offshore drilling. Both laboratory and field tests were conducted to collect the characteristics of the hydraulic pulse generator. The relationships between flow rate and pressure amplitude, pressure loss and pulse frequency were obtained, which can be used to optimize operation parameters for hydraulic pulse jet drilling. Meanwhile a bottom hole assembly (BHA) for pulse jet drilling has been designed, combining the hydraulic pulse generator with the conventional BHA, positive displacement motor, and rotary steerable system (RSS) etc. Furthermore, the hydraulic pulse jet technique has been successfully applied in more than 10 offshore wells in China. The depth of the applied wells ranged from 2,000 m to 4,100 m with drilling bit diameters of 311 mm and 216 mm. The field application results showed that hydraulic pulse jet technique was feasible for various bit types and formations, and that ROP could be significantly increased, by more than 25%.展开更多
基金The 11th Postgraduate Technology Innovation Project of North University of China(No.20141142)
文摘During the test on transient pressure signal in explosion field,false trigger caused by field interference can lead to test failure.To improve the stability of test system,a signal detection and recognition technology is proposed for transient pressure test system.In the process of signal acquisition,firstly,electrical levels are monitored in real time to find effective abrupt changes and mark them;then the effective data segments are detecdted totected;thus the effective signals can be acquired in turn finally.The experimental results show that the shock wave signal can be collected effectively and the reliability of the test system can be improved after removal of interferences.
基金The 11th Postgraduate Technological Innovation Project of North University of China(No.20141150)
文摘For the shock wave overpressure signal measurement of explosion field, the type and equivalent of the ammunition as well as the distance from test nodes to ground zero have a great influence on the characteristics of shock wave signal. To ensure that shock wave signal with different characteristic parameters can be collected completely in the test of shooting range, a tran- sient pressure signal storage system with configurable parameters is presented. In order to meet the requirements of different test nodes, the system can set parameters of all test nodes by wireless communication in explosion field. The feasibility and re- liability of the system are fully verified through transient pressure measurement in explosion field.
文摘Aiming at harsh environment of cluster bombs center tube explosion dispersion and difficulties in installation of traditional test systems,a storage test system based on 16-bit ultra-low power microcontroller MSP430 is designed in order to acquire gas pressure during cluster bombs dispersion.To meet the requirement of low power consumption,the working states of system's modules during data acquisition are elaborated and the equation to calculate the gas pressure change during cylindrical center tube opening the hatch is deduced.The field test is conducted and good test results are obtained.
文摘BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their occurrence.AIM To investigate whether coronary spasms can be predicted using changes in intracoronary artery pressure measured using a pressure wire during the SPT.METHODS Seventy patients underwent SPTs with pressure-wire measurement of intracoronary artery pressure.During each SPT,the pressure wire was advanced into the distal portion of the right coronary artery(RCA)and left anterior descending coronary artery,and the ratio of intracoronary pressure to aortic pressure(Pd/Pa)was monitored.Coronary spasm was defined as an arterial narrowing of>90%in response to the administration of acetylcholine(ACh),with chest symptoms and/or ischemic electrocardiographic changes.ACh was administered to the RCA at low,moderate,or high doses of 20,50,or 80μg,respectively,and to the left coronary artery(LCA)at low,moderate,or high doses of 50,100,or 200μg,respectively.Coronary arteries with coronary spasms at low doses of ACh were defined as group L,and those with coronary spasms at moderate or high doses were defined as group MH.Those who did not occur coronary spasms at any ACh dose were designated as group N.RESULTS Among the 132 coronary arteries assessed using a pressure wire,there were 49 in group N,25 in group L,and 58 in group MH.Baseline Pd/Pa was the lowest in group L(P=0.001).The decrease in the Pd/Pa between baseline to low doses of ACh was lower in group MH than in group N(P<0.001).A receiver-operating characteristics analysis showed that the cutoff baseline Pd/Pa value for predicting group L was 0.95,with a sensitivity of 0.600(15/25)and a specificity of 0.713(76/107)and that the cutoff value of Pd/Pa from baseline to low doses of ACh for predicting group MH was−0.04,with a sensitivity of 0.741(43/58)and a specificity of 0.694(34/49).CONCLUSION These findings suggest that indices of intracoronary pressure during SPT may be useful means for predicting the occurrence of coronary spasms.
文摘Background and Aims: Pulse pressure variation (PPV) is a reliable and predictive dynamic parameter presently being utilized for fluid responsiveness. In the operating room, fluid administration based on PPV monitoring helps the physician in deciding whether to volume resuscitate or use interventions in patients undergoing surgery. Propofol is an intravenous induction agent which lowers blood pressure. There are multiple causes such as depression in cardiac output, and peripheral vasodilatation for hypotension. We undertook this study to observe the utility of PPV as a guide to fluid therapy after propofol induction. Primary outcome of our study was to monitor PPV as a marker of fluid responsiveness for the hypotension caused by propofol induction. Secondary outcome included the correlation of PPV with other hemodynamic parameters like heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP);after induction with propofol at regular interval of time. Methods: A total number of 90 patients were recruited. Either of the radial artery was then cannulated under local anaesthesia with 20G VygonLeadercath arterial cannula and invasive monitoring transduced. A baseline recording of heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) and PPV was then recorded. Patients were then induced with predetermined doses of propofol (2 mg/kg) and recordings of HR, SBP, DBP, and PPV were taken at 5, 10 and 15 minutes. Results: Intraoperatively, PPV was significantly higher at 5 minutes and significantly lower at 15 minutes after induction. It was observed that there were no statistically significant correlations between PPV and SBP or DBP. PPV was strongly and directly associated with HR. Conclusion: We were able to establish that PPV predicts fluid responsiveness in hypotension caused by propofol induction;and can be used to administer fluid therapy in managing such hypotension. However, PPV was not directly correlated with hypotension subsequent to propofol administration.
文摘Reliability of medical devices such as infusion pumps is extremely important because these devices are being used in patients who are in critical condition. Occlusion pressure, as an important parameter of infusion pumps, should be detected when an occlusion occurred. How-ever, infusion pumps’ occlusion pressure could not be tested and the performance of these pumps is not known to us. In order to test the occlusion pressure of infusion pump, a testing system has been put forward according to standards of IEC 60601-2-24:1998/ GB 9706.27- 2005. The system is comprised of sensor, acquisition card, three-way tap and so on;this system is controlled by a PC. At the same time, sampling rate could be changed if necessary and test time could be recorded. And then the characteristics of this system were studied, such as linear, effects of pump rates and different pumps. The system remained linear in a given environment. The higher is the pump rate, the faster is the time to reach occlusion condi-tion. The testing system has been proved to be effective in testing the occlusion pressure of infusion pumps and the accuracy error of pressure is content the demand of ±1% of range.
基金support from Shenzhen Municipal Development and Reform Commission(Grant Number:SDRC[2016]172)Shenzhen Science and Technology Program(Grant No.KQTD20170810150821146)Interdisciplinary Research and Innovation Fund of Tsinghua Shenzhen International Graduate School,and Shanghai Shun Feng Machinery Co.,Ltd.
文摘It remains challenging to effectively estimate the remaining capacity of the secondary lithium-ion batteries that have been widely adopted for consumer electronics,energy storage,and electric vehicles.Herein,by integrating regular real-time current short pulse tests with data-driven Gaussian process regression algorithm,an efficient battery estimation has been successfully developed and validated for batteries with capacity ranging from 100%of the state of health(SOH)to below 50%,reaching an average accuracy as high as 95%.Interestingly,the proposed pulse test strategy for battery capacity measurement could reduce test time by more than 80%compared with regular long charge/discharge tests.The short-term features of the current pulse test were selected for an optimal training process.Data at different voltage stages and state of charge(SOC)are collected and explored to find the most suitable estimation model.In particular,we explore the validity of five different machine-learning methods for estimating capacity driven by pulse features,whereas Gaussian process regression with Matern kernel performs the best,providing guidance for future exploration.The new strategy of combining short pulse tests with machine-learning algorithms could further open window for efficiently forecasting lithium-ion battery remaining capacity.
文摘Recent developments in brain magnetic resonance imaging using advanced Susceptibility Weighted Imaging (SWI) have significantly increased the detection and prevalence of Cerebral Microbleeds (CMBs). Here, we aimed to explore the association between Pulse Pressure (PP) and CMBs. Having been implicated in various arteriopathies, we hypothesized that elevated PP could also be a risk for CMBs. A retrospective case-control study was conducted from August 2021 to September 2022 at Zhongnan Hospital of Wuhan University China. Extracted data were analyzed in SPSS. Chi-square test, binary logistic regression, and Spearman’s correlation analysis were conducted.104 patients were analyzed. Univariate analysis showed no significant association between PP and CMBs, OR 1.65 (95% CI: 0.737 - 3.694;p > 0.05), while DBP and alcohol consumption were significant, ORs 2.956 (95% CI: 1.249 - 6.997, p < 0.05) and 2.525 (95% CI: 1.062 - 6.002, p < 0.05) respectively. Multivariate analysis, showed that PP was significantly associated with CMBs, OR 3.194 (95% CI: 1.024 - 9.964, p < 0.05) in combination with SBP, DBP, gender, age, smoking and alcohol consumption. Taken together, the study showed that elevated PP is associated with CMB, but is not an independent risk factor for CMBs.
基金support provided by EIG EURIDICE/SCK.CEN(Belgium)through a PhD collaboration project with International Centre for Numerical Methods in Engineering(CIMNE,Spain)
文摘Boom clay formation is a potential natural host rock for geological disposal of high-level nuclear waste in Belgium.Heating pulse tests with controlled power supply(maximum temperature was limited to 85℃) and controlled hydraulic boundary conditions were performed under nearly constant volume conditions to study the impact of thermal loading on the clay formation.Selected test results of intact borehole samples retrieved in horizontal direction are presented and discussed.The study focuses on the time evolution of temperature and pore water pressure changes along heating and cooling paths,i.e.pore pressure build-up during quasi-undrained heating and later dissipation at constant temperature.
基金supported by National Natural Science Foundation of China(Nos.11076026,50707032)the Knowledge Innovation Program of the Chinese Academy of Sciences(No.KGCX2-YW-339)Opening Project of State Key Laboratory of Polymer Materials Engineering in Sichuan University(No.KF201103)
文摘Dielectric barrier discharge (DBD) excitated by pulsed power is a promising method for producing nonthermal plasma at atmospheric pressure. Discharge characteristic in a DBD with salt water as electrodes by a home-made unipolar nanosecond-pulse power source is presented in this paper. The generator is capable of providing repetitive pulses with the voltage up to 30 kV and duration of 70 ns at a 300 Ω resistive load. Applied voltage and discharge current are measured under various experimental conditions. The DBD created between two liquid electrodes shows that the discharge is homogeneous and diffuse in the whole discharge regime, Spectra diagnosis is conducted by an optical emission spectroscopy. The air plasma has strong emission from nitrogen species below 400 nm, notably the nitrogen second positive system.
文摘AIM:To compare the intraocular pressure(IOP)peaks and fluctuations using water drinking tests(WDTs)and mean diurnal IOP among Filipino patients with normal eyes and glaucoma suspectsMETHODS:This prospective study included normal and glaucoma suspect patients.Each patient underwent both WDT and mean diurnal examination on separate visits.For mean diurnal examination,IOP was recorded every 2 h for 8 h while in WDT,IOP was recorded prior to WDT,and postWDT at 5,15,30,45,and 60 min.IOP peak was recorded as the highest IOP for both methods,and IOP fluctuation was recorded as highest IOP minus lowest IOP.RESULTS:With the comparison of diagnostic tests,both normal eyes and glaucoma suspect groups,the peak IOP was caught at 15 min.Comparative analysis of both groups also showed that the peak IOP measurements were statistically higher for the WDT compared to mean diurnal IOP(P=0.039,P=0.048 under normal group and P=0.032 and P=0.031 under glaucoma suspect group).Similarly,the WDT had a statistically higher mean IOP fluctuation score than the mean diurnal IOP method in both groups(P=0.003,P=0.011 under normal group;P=0.002 and P=0.005 under glaucoma suspect group).CONCLUSION:This study shows that WDT is a comparable diagnostic exam in predicting IOP fluctuations than mean diurnal measurement.WDT is a promising diagnostic procedure for risk assessment in glaucoma.
基金Project 2006CB202204-3 supported by the National Basic Research Program of China
文摘Given the problem of the long time required for testing gas pressure, we propose a fast-test method in which we used a technique of fast borehole sealing and air replenishing. Based on the characteristics of gas emission from boreholes to be tested, we built a theoretical model for calculating parameters during the process of increasing natural pressure and aeration. Using this model, we investigated the effect of different aeration conditions on velocity of pressure tests. The result shows that: 1) aerating air into boreholes can speed up gas pressure tests and 2) the more similar the pressure of the aerated air to the original gas pressure, the smaller the gas volume absorbed by coal and the shorter the time needed in pressure test. A case study in the Lu’an mining area shows that the time needed for gas pressure test is only 4 h using our method of aeration and 29 h under conditions of increasing natural pressure, saving time by 86.2%. This case study also indicates that, by using the aeration method, only one hour is needed for gas pressure to reach a stable state, which breaks the record of the shortest time needed for gas pressure tests in China.
文摘Based on the documentation of the invited paper and the subsequent discussion at a virtual conference,discoveries are indicated,which are summarized in the following paper for further evaluation on the topic of non-thermal forces using terms of extremely powerful components of Maxwell’s stress tensor at the interaction of CPA(chirped pulse amplification)laser pulses in the fusion plasmas of hydrogen with the isotope 11 of boron.This is caused by a recoil mechanism given by the Fresnel formulas of the suppression of the reflectivity of inhomogeneous plasma given by optical constants of the plasma properties.
基金Ministry of Higher Education of Malaysia for funding the project on PEC NDT at IIUM through the research grant FRGS16-059-0558supported by the National Natural Science Foundation of China under research grants 51677187 and 51307172
文摘Pulsed eddy current (PEC) non-destructive test- ing and evaluation (NDT&E) has been around for some time and it is still attracting extensive attention from researchers around the globe, which can be witnessed through the reports reviewed in this paper. Thanks to its richness of spectral components, various applications of this technique have been proposed and reported in the lit- erature covering both structural integrity inspection and material characterization in various industrial sectors. To support its development and for better understanding of the phenomena around the transient induced eddy currents, attempts for its modelling both analytically and numeri- cally have been made by researchers around the world. This review is an attempt to capture the state-of-the-art development and applications of PEC, especially in the last 15 years and it is not intended to be exhaustive. Future challenges and opportunities for PEC NDT&E are also presented.
文摘Owing to the characteristics of arc ion plating(AIP) technique, the structure and composition of TiAlN films can be tailored by controlling of various parameters such as compositions of target materials, N2 partial pressure, substrate bias and so on. In this study, several titanium aluminum nitride films were deposited on 1Cr11Ni2W2MoV steel for compressor blade of areo-engine under different d.c pulse bias voltage and nitrogen partial pressure. The effects of substrate pulse bias and nitrogen partial pressure on the deposition rate, droplet formation, microstruture and elemental component of the films were investigated.
基金supported by National Natural Science Foundation of China (Nos. 50707032, 11076026)the Knowledge Innovation Program of the Chinese Academy of Sciences (No. KGCX2-YW-339)+1 种基金the National Basic Research Program of China (No. 2011CB209405)the State Key Laboratory of Control and Simulation of Power Systems and Generating Equipment in Tsinghua University (No. SKLD09KZ05)
文摘Dielectric barrier discharge (DBD) between two cylindrical glass containers with salt water generated by a nanosecond repetitively pulsed power generator is reported. The electrical parameters, luminous images and spectrum diagnosis are presented. It is shown that the DBD possesses a large discharge current and an intense optical emission from the nitrogen second positive system below 400 nm. The gas temperature remains very close to room temperature regardless of pulse polarity. Luminous photographs with a short exposure time down to 2 ns indicate that no filament is observed and the discharge is homogeneous.
文摘AIM: To investigate the effects of body mass index (BMI) on intraocular pressure (IOP) and ocular pulse amplitude(OPA). METHODS: Totally 140 healthy individuals without any systemic diseases were included in the study. BMI (kg/m2) was calculated for every individual. IOP and OPA were measured with Pascal Dynamic contour tonometer (DCT). Blood pressure was also measured along with the DCT. The patients were divided into three groups according to BMI as: Group1, BMI<25; Group2, 25≤BMI<30; Group3, BMI≥30. Mean values of IOP, OPA, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were used in statistical analysis.RESULTS: In Group1, the means of IOP, OPA, were 16.8±2.3mmHg, 2.7±0.7mmHg respectively; and SBP, DBP were 120.0±6.1mmHg, and 77.4±5.6mmHg respectively. In group2, the mean IOP, OPA, SBP, and DBP were found to be 16.6±2.1mmHg, 2.4±0.7mmHg, 121.7±5.3mmHg, and 79.5±4.9mmHg respectively. In group3, the mean IOP, OPA, SBP, and DBP were found to be 17.3±1.7mmHg, 2.1±0.7mmHg, 122.4±5.7mmHg, and 79.7±5.2mmHg respectively. There were no statistically significant difference between groups in terms of IOP, SBP and DBP, while OPA values were significantly lower in group3 (P=0.001). CONCLUSION: Decreased OPA values in individuals with higher BMI may indicate that subjects with higher BMI have lower choroidal perfusion and lower ocular blood flow.
基金supported by the Fundamental Research Funds of Shandong University,China(No.2016JC016)
文摘In this work the effects of O_2 concentration on the pulsed dielectric barrier discharge in helium-oxygen mixture at atmospheric pressure have been numerically researched by using a one-dimensional fluid model in conjunction with the chosen key species and chemical reactions.The reliability of the used model has been examined by comparing the calculated discharge current with the reported experiments. The present work presents the following significant results. The dominative positive and negative particles are He_2~+ and O_2^-, respectively, the densities of the reactive oxygen species(ROS) get their maxima nearly at the central position of the gap, and the density of the ground state O is highest in the ROS. The increase of O_2 concentration results in increasingly weak discharge and the time lag of the ignition. For O_2 concentrations below 1.1%,the density of O is much higher than other species, the averaged dissipated power density presents an evident increase for small O_2 concentration and then the increase becomes weak. In particular,the total density of the reactive oxygen species reaches its maximums at the O_2 concentration of about 0.5%. This characteristic further convinces the experimental observation that the O_2 concentration of 0.5% is an optimal O_2/He ratio in the inactivation of bacteria and biomolecules when radiated by using the plasmas produced in a helium oxygen mixture.
基金financial support from the Program for New Century Excellent Talents in University (No. NCET-12-0971)
文摘Offshore drilling has attracted more attention than ever before due to the increasing worldwide energy demand especially in China. High cost, long drilling cycles, and low rate of penetration (ROP) represent critical challenges for offshore drilling operations. The hydraulic pulse generator was specifically designed, based on China offshore drilling technologies and parameters, to overcome problems encountered during offshore drilling. Both laboratory and field tests were conducted to collect the characteristics of the hydraulic pulse generator. The relationships between flow rate and pressure amplitude, pressure loss and pulse frequency were obtained, which can be used to optimize operation parameters for hydraulic pulse jet drilling. Meanwhile a bottom hole assembly (BHA) for pulse jet drilling has been designed, combining the hydraulic pulse generator with the conventional BHA, positive displacement motor, and rotary steerable system (RSS) etc. Furthermore, the hydraulic pulse jet technique has been successfully applied in more than 10 offshore wells in China. The depth of the applied wells ranged from 2,000 m to 4,100 m with drilling bit diameters of 311 mm and 216 mm. The field application results showed that hydraulic pulse jet technique was feasible for various bit types and formations, and that ROP could be significantly increased, by more than 25%.