Based on the scheme of damped harmonic oscillator quantization and thermo-field dynamics (TFD), the quantization of mesoscopic damped double resonance RLC circuit with mutual capacitance-inductance coupling is propo...Based on the scheme of damped harmonic oscillator quantization and thermo-field dynamics (TFD), the quantization of mesoscopic damped double resonance RLC circuit with mutual capacitance-inductance coupling is proposed. The quantum fluctuations of charge and current of each loop in a squeezed vacuum state are studied in the thermal excitation case. It is shown that the fluctuations not only depend on circuit inherent parameters, but also rely on excitation quantum number and squeezing parameter. Moreover, due to the finite environmental temperature and damped resistance, the fluctuations increase with the temperature rising, and decay with time.展开更多
1 H-magnetic resonance spectroscopy imaging and diffusion tensor imaging were performed in 19 patients with mild depression and in 13 controls.The mean age of the patients was 31 years.The mean Hamilton depression sco...1 H-magnetic resonance spectroscopy imaging and diffusion tensor imaging were performed in 19 patients with mild depression and in 13 controls.The mean age of the patients was 31 years.The mean Hamilton depression score of the patients was 22.5±13.2.N-acetylaspartate,choline and creatine concentrations and the average diffusion coefficient and fractional anisotropy values were measured in the bilateral hippocampus,striatum,thalamus and prefrontal deep white matter. Compared with the control group,the mild depressed patients had:(1)a higher choline/creatine ratio and a negative correlation between the choline/creatine ratio and the average diffusion coefficient in the hippocampus;(2)a lower choline/creatine ratio and a higher fractional anisotropy in the striatum;(3)a lower fractional anisotropy and a positive correlation between the fractional anisotropy and the choline/creatine ratio in the prefrontal deep white matter;and(4)a higher average diffusion coefficient and a positive correlation between the choline/creatine ratio and the N-acetylaspartate/creatine ratio in the thalamus,as well as positive correlation between the choline/creatine ratio and Hamilton depression scores.These data suggest evidence of abnormal connectivity in neurofibrotic microstructures and abnormal metabolic alterations in the limbic-cortical-striatal-pallidal-thalamic neural circuit in patients with mild depression.展开更多
The existence of specific biorhythms and the role of geomagnetic and/or solar magnetic activities are well-established by appropriate correlations in chronobiology. From a physical viewpoint, there are two different a...The existence of specific biorhythms and the role of geomagnetic and/or solar magnetic activities are well-established by appropriate correlations in chronobiology. From a physical viewpoint, there are two different accesses to biorhythms to set up connections to molecular processes: quantum mechanical perturbation theoretical methods and their resonance dominators to characterize specific interactions between constituents. These methods permit the treatment of molecular processes by circuits with characteristic resonances and “beat-frequencies”, which result from primarily fast physical processes. As examples, the tunneling processes between DNA base pairs (H bonds), the ATP decomposition and the irradiation of tumor cells are accounted for.展开更多
Wireless power transfer experiment by using magnetic coupling resonance can be used for electric vehicles,portable electronic equipment,etc.It is clear that this technology will bring convenience and productivity.So h...Wireless power transfer experiment by using magnetic coupling resonance can be used for electric vehicles,portable electronic equipment,etc.It is clear that this technology will bring convenience and productivity.So how can we do the wireless power transfer experiment?This thesis will show the experiment from two aspects:the first is to understand and explore the theory of this experiment.The second is to raise the questions I met and the utility of this technology.By studying the knowledge[1]of the theory,I have the fundamental understanding of alternating current,resonance circuit,and electro-magnetic induction[2].After the experiment,I also collect analyze the data.展开更多
LC circuit resonance frequency measurement often requires the use of professional analysis instruments such as LCR meters,vector network analyzers,but currently such instruments on the market are expensive,and it is d...LC circuit resonance frequency measurement often requires the use of professional analysis instruments such as LCR meters,vector network analyzers,but currently such instruments on the market are expensive,and it is difficult for non-professional institute personnel to access.Here comes unnecessary trouble.In view of this situation,a test method for measuring the resonance frequency using only a digital storage oscilloscope is proposed.Using the impulse signal to obtain the system response,the response waveform period can be observed through the oscilloscope.展开更多
High Te superconductor (HTS) technology has been used to develop a unique high Q resonant circuit. Such circuit or device has some special characteristics such as very high voltage generation. Theoretical study and ...High Te superconductor (HTS) technology has been used to develop a unique high Q resonant circuit. Such circuit or device has some special characteristics such as very high voltage generation. Theoretical study and experimental approaches have proceeded for the concept verification. This paper presents the theory about this high Q resonant circuit. The operation principle of the circuit is described. A practical prototype for HTS high voltage generation is also demonstrated. The experiment result shows that very high voltages can be achieved by the developed method using HTS technology.展开更多
Aim To provide technical parameters for development of quartz gyro. Methods Theory of elastic beam was applied to piezoelectric beam. Based on the concept of equivalent volume force and energy conservation, the f...Aim To provide technical parameters for development of quartz gyro. Methods Theory of elastic beam was applied to piezoelectric beam. Based on the concept of equivalent volume force and energy conservation, the formula of electrode location efficiency was derived. And the electric system was compared with the dynamic one according to the principle of equivalent circuit for piezoelectric crystal, and the general formulae of the parameters for the equivalent circuit, R n L n C n , were derived. Results and Conclusion Optimum electrode location is chosen, and the derived equivalent circuit parameters are the theoretical base of the circuit design for quartz gyro.展开更多
Cerebral small vessel disease(CSVD) is a common etiology of vascular cognitive impairment with no dementia(V-CIND). Studies have revealed that cerebral microbleeds(CMBs), a feature of CSVD, contribute to cogniti...Cerebral small vessel disease(CSVD) is a common etiology of vascular cognitive impairment with no dementia(V-CIND). Studies have revealed that cerebral microbleeds(CMBs), a feature of CSVD, contribute to cognitive impairment. However, the association between CMBs and dementia conversion in individuals with V-CIND is still unclear. Here, we analyzed the predictive role of CMBs in the conversion from V-CIND to dementia in CSVD patients. We recruited and prospectively assessed 85 patients with CSVD and V-CIND. V-CIND was evaluated using a series of comprehensive neuropsychological scales, including the Chinese version of the Montreal Cognitive Assessment and the Clinical Dementia Rating. MRI assessments were used to quantify lacunar infarcts, white matter hyperintensities, CMBs, and medial temporal lobe atrophy. Eighty-two of the 85 patients completed the assessment for dementia conversion at a 1-year follow-up assessment. Multivariate logistic regression analyses were conducted to examine independent clinical and MRI variables associated with dementia conversion. Twenty-four patients(29.3%) had converted to dementia at the 1-year follow-up, and these individuals had significantly more CMBs in the fronto-subcortical circuits. Multivariate logistic regression analyses revealed that the patients with CMBs in the fronto-subcortical circuits(odds ratio = 4.4; 95% confidence interval: 1.602-12.081, P = 0.004) and 5 or more CMBs overall(odds ratio = 17.6, 95% confidence interval: 3.23-95.84, P = 0.001) had a significantly increased risk of dementia at the 1-year follow-up. These findings indicate that CMBs in the fronto-subcortical circuits may be predictive of dementia conversion in CSVD patients with V-CIND, and thus extend the clinical significance of CMBs.展开更多
We demonstrated a novel method to measure the unloaded quality factor(Q factor) of high-Q resonant cavities. This method was used to obtain data with low errors and calculate the unloaded Q factor. This procedure was ...We demonstrated a novel method to measure the unloaded quality factor(Q factor) of high-Q resonant cavities. This method was used to obtain data with low errors and calculate the unloaded Q factor. This procedure was more reliable than traditional methods. The data required for the method were near the resonant frequency,not at the half-power points of the reflection coefficient curve or Smith chart. We applied the new method to measure a resonant cavity with an unloaded Q factor of^100,000, obtaining good agreement between the measured and theoretical results.展开更多
A full planar tunable band pass resonator is introduced, which is constructed by using novel symmetric step impedance resonator (SIR) and hyperabrupt varactors for wide bandwidth tuning and size reduction. The equiv...A full planar tunable band pass resonator is introduced, which is constructed by using novel symmetric step impedance resonator (SIR) and hyperabrupt varactors for wide bandwidth tuning and size reduction. The equivalent circuit model of the proposed resonator is set up. Theoretical analysis based on transmission line as well as odd and even-mode method is completed. The attractiveness of the approach presented lies in its simplicity. Based on the detailed analysis, a 6 GHz to 10 GHz varactor tuned resonator is designed, fabricated, and measured. It shows wideband tuning ability of 37%. The experimental results of the resonator have a good agreement with the analysis results.展开更多
In this paper, we design and fabricate a silicon integrated optical filter consisting of two cascaded micro-ring resonators and two straight waveguides. Two micro-heaters are fabricated on the top of two micro-rings r...In this paper, we design and fabricate a silicon integrated optical filter consisting of two cascaded micro-ring resonators and two straight waveguides. Two micro-heaters are fabricated on the top of two micro-rings respectively, which are employed to modulate the micro-rings to perform the function of a tunable optical filter by the thermo–optic effect. The static response test indicates that the extinction ratio and 3-d B bandwidth are 29.01 d B and 0.21 nm respectively, the dynamic response test indicates that the 10%–90% rise and 90%–10% fall time of the filter are 16 μs and 12 μs, respectively,which can meet the requirements of optical communication and information processing. Finally, the power consumption of the device is also characterized, and the total power consumption is about 9.43 m W/nm, which has been improved efficiently.展开更多
A theoretical model is developed for calculating the eigenmodes of the multi-gap resonant cavity. The structure of concern is a kind of ladder-type circuit, offering the advantages of easy fabrication, high characteri...A theoretical model is developed for calculating the eigenmodes of the multi-gap resonant cavity. The structure of concern is a kind of ladder-type circuit, offering the advantages of easy fabrication, high characteristic impedance (R/Q), and thermal capacity in the millimeter wave to THz regime. The eigenfunction expansion method is used to establish the field expressions for the gaps and the coupling region. Then, the match conditions at the interface are employed, which leads to a group of complicate boundary equations in the form of an infinite series. To facilitate the mathematical treatments and perform a highly efficient calculation, these boundary equations are transformed into the algebraic forms through the matrix representations. Finally, the concise dispersion equation is obtained. The roots of the dispersion equation include both the axial modes in the gaps, which include the fundamental and the high-order modes, and the cavity modes in the coupling region. Extensive numerical results are presented and the behaviors of the multi-gap resonant cavity are examined.展开更多
We propose a scheme to transmit information via the statistical distribution of excitations of a nanomechanical resonator. It employs a controllable coupling between this system and a Cooper pair box. The success prob...We propose a scheme to transmit information via the statistical distribution of excitations of a nanomechanical resonator. It employs a controllable coupling between this system and a Cooper pair box. The success probability and the fidelity are calculated and compared with those obtained in an atom-field system in different regimes. Addtionaly, the scheme can also be applied to prepare low excited Fock states.展开更多
Recently, resonant AC/DC converter has been accepted by the industry. However, the efficiency will be decreased at light load. So, a novel topology with critical controlling mode combined with resonant ones is propose...Recently, resonant AC/DC converter has been accepted by the industry. However, the efficiency will be decreased at light load. So, a novel topology with critical controlling mode combined with resonant ones is proposed in this paper. The new topology can correspond to a 90 plus percent of power converting. So,a novel topology of an state of-art integrated circuit, which can be used as power management circuit, has been designed based on the above new topology. A simulator which is specific suitable for the power controller has been founded in this work and it has been used for the simulation of the novel architecture and the proposed integrated circuit.展开更多
Once people have a well-trained motor skill, their performance becomes stabilized and achieving substantial improvement is difficult. Recently, we have shown that even a plateaued hand motor skill can be upgraded with...Once people have a well-trained motor skill, their performance becomes stabilized and achieving substantial improvement is difficult. Recently, we have shown that even a plateaued hand motor skill can be upgraded with short-period electrical stimulation to the hand prior to the task. Here, we identify the neuronal substrates underlying the improvement of the plateaued skill by examining the enhanced functional connectivity in the sensory-motor regions that are associated with motor learning. We measured brain activity using functional magnetic resonance imaging and performed psychophysiological interaction analysis. We recruited seven right-handed very-well trained participants, whose motor performance of continuously rotating two balls with their right hands became stabilized at higher performance levels. We prepared two experiments, in each of which they repeated an experimental run 16 times. In each run, they performed this cyclic rotation as many times as possible in 16 s. In the thenar-stimulation experiment, we applied 60-s stimulation to the thenar muscle before each of the 5th - 12th runs, and the others were preceded by ineffective sham stimulation. In the control experiment, the sham was always provided. Thenar stimulation enabled the participants to perform the movements at higher cycles. In association with this performance improvement, we found enhanced activity couplings between the primary motor cortex and the sensorimotor territory of the putamen and between the cerebellum and the primary sensorimotor cortices, without any quantitative activity increase. Neither behavioral change nor these increased activity couplings were observed in the control.Thus, in contrast to the stable neuronal states in the cortico-subcortical motor circuits when the well-learned task is repeated at the later stages of motor skill learning, plastic changes in the motor circuits seem to be required when the plateaued skill is upgraded, and the stimulation may entail a state of readiness for the plastic change that allows subsequent performance improvement.展开更多
Resonant tunneling diode (RTD) of AlAs/InGaAs/AlAs double barrier-single well structure was designed and fabricated. The devices showed current-voltage characteristics with peak-valley current ratio of 4 : 1 at roo...Resonant tunneling diode (RTD) of AlAs/InGaAs/AlAs double barrier-single well structure was designed and fabricated. The devices showed current-voltage characteristics with peak-valley current ratio of 4 : 1 at room temperature. The scattering parameter of RTD was measured by using an HP8510(C) network analyzer. Equivalent circuit parameters were obtained by curve fitting and optimized. The RTD switching time was estimated using the measured capacitance and average negative differential resistance. The minimum rise time of the sample was estimated to be 21 ps.展开更多
Recently, resonant AC/DC converter has been accepted by the industry. However, the efficiency will be decreased at light load. So, a novel topology with critical controlling mode combined with resonant ones is propose...Recently, resonant AC/DC converter has been accepted by the industry. However, the efficiency will be decreased at light load. So, a novel topology with critical controlling mode combined with resonant ones is proposed in this paper. The new topology can correspond to a 90 plus percent of power converting. So,a novel topology of an state of art integrated circuit, which can be used as power management circuit, has been designed based on the above new topology. A simulator which is specifically suitable for the power controller has been founded in this work and it has been used for the simulation of the novel architecture and the proposed integrated circuit.展开更多
The zero-voltage quasi-resonant boost switching DC-DC converter has been inves-tigated by using the time averaging equivalent circuit approach of periodically switching linearnetworks.The DC steady state and AC small ...The zero-voltage quasi-resonant boost switching DC-DC converter has been inves-tigated by using the time averaging equivalent circuit approach of periodically switching linearnetworks.The DC steady state and AC small signal characteristics of the converter are also given.展开更多
基金Project supported by the Natural Science Foundation of Heze University of Shandong Province, China (Grant No XY05WL01), the University Experimental Technology Foundation of Shandong Province, China (Grant No S04W138), the Natural Science Foundation of Shandong Province, China (Grant No Y2004A09) and the National Natural Science Foundation of China (Grant No 10574060).
文摘Based on the scheme of damped harmonic oscillator quantization and thermo-field dynamics (TFD), the quantization of mesoscopic damped double resonance RLC circuit with mutual capacitance-inductance coupling is proposed. The quantum fluctuations of charge and current of each loop in a squeezed vacuum state are studied in the thermal excitation case. It is shown that the fluctuations not only depend on circuit inherent parameters, but also rely on excitation quantum number and squeezing parameter. Moreover, due to the finite environmental temperature and damped resistance, the fluctuations increase with the temperature rising, and decay with time.
文摘1 H-magnetic resonance spectroscopy imaging and diffusion tensor imaging were performed in 19 patients with mild depression and in 13 controls.The mean age of the patients was 31 years.The mean Hamilton depression score of the patients was 22.5±13.2.N-acetylaspartate,choline and creatine concentrations and the average diffusion coefficient and fractional anisotropy values were measured in the bilateral hippocampus,striatum,thalamus and prefrontal deep white matter. Compared with the control group,the mild depressed patients had:(1)a higher choline/creatine ratio and a negative correlation between the choline/creatine ratio and the average diffusion coefficient in the hippocampus;(2)a lower choline/creatine ratio and a higher fractional anisotropy in the striatum;(3)a lower fractional anisotropy and a positive correlation between the fractional anisotropy and the choline/creatine ratio in the prefrontal deep white matter;and(4)a higher average diffusion coefficient and a positive correlation between the choline/creatine ratio and the N-acetylaspartate/creatine ratio in the thalamus,as well as positive correlation between the choline/creatine ratio and Hamilton depression scores.These data suggest evidence of abnormal connectivity in neurofibrotic microstructures and abnormal metabolic alterations in the limbic-cortical-striatal-pallidal-thalamic neural circuit in patients with mild depression.
文摘The existence of specific biorhythms and the role of geomagnetic and/or solar magnetic activities are well-established by appropriate correlations in chronobiology. From a physical viewpoint, there are two different accesses to biorhythms to set up connections to molecular processes: quantum mechanical perturbation theoretical methods and their resonance dominators to characterize specific interactions between constituents. These methods permit the treatment of molecular processes by circuits with characteristic resonances and “beat-frequencies”, which result from primarily fast physical processes. As examples, the tunneling processes between DNA base pairs (H bonds), the ATP decomposition and the irradiation of tumor cells are accounted for.
文摘Wireless power transfer experiment by using magnetic coupling resonance can be used for electric vehicles,portable electronic equipment,etc.It is clear that this technology will bring convenience and productivity.So how can we do the wireless power transfer experiment?This thesis will show the experiment from two aspects:the first is to understand and explore the theory of this experiment.The second is to raise the questions I met and the utility of this technology.By studying the knowledge[1]of the theory,I have the fundamental understanding of alternating current,resonance circuit,and electro-magnetic induction[2].After the experiment,I also collect analyze the data.
文摘LC circuit resonance frequency measurement often requires the use of professional analysis instruments such as LCR meters,vector network analyzers,but currently such instruments on the market are expensive,and it is difficult for non-professional institute personnel to access.Here comes unnecessary trouble.In view of this situation,a test method for measuring the resonance frequency using only a digital storage oscilloscope is proposed.Using the impulse signal to obtain the system response,the response waveform period can be observed through the oscilloscope.
文摘High Te superconductor (HTS) technology has been used to develop a unique high Q resonant circuit. Such circuit or device has some special characteristics such as very high voltage generation. Theoretical study and experimental approaches have proceeded for the concept verification. This paper presents the theory about this high Q resonant circuit. The operation principle of the circuit is described. A practical prototype for HTS high voltage generation is also demonstrated. The experiment result shows that very high voltages can be achieved by the developed method using HTS technology.
文摘Aim To provide technical parameters for development of quartz gyro. Methods Theory of elastic beam was applied to piezoelectric beam. Based on the concept of equivalent volume force and energy conservation, the formula of electrode location efficiency was derived. And the electric system was compared with the dynamic one according to the principle of equivalent circuit for piezoelectric crystal, and the general formulae of the parameters for the equivalent circuit, R n L n C n , were derived. Results and Conclusion Optimum electrode location is chosen, and the derived equivalent circuit parameters are the theoretical base of the circuit design for quartz gyro.
基金supported by the Medical Scientific Research Foundation of Guangdong Province,China(No.A2015160)
文摘Cerebral small vessel disease(CSVD) is a common etiology of vascular cognitive impairment with no dementia(V-CIND). Studies have revealed that cerebral microbleeds(CMBs), a feature of CSVD, contribute to cognitive impairment. However, the association between CMBs and dementia conversion in individuals with V-CIND is still unclear. Here, we analyzed the predictive role of CMBs in the conversion from V-CIND to dementia in CSVD patients. We recruited and prospectively assessed 85 patients with CSVD and V-CIND. V-CIND was evaluated using a series of comprehensive neuropsychological scales, including the Chinese version of the Montreal Cognitive Assessment and the Clinical Dementia Rating. MRI assessments were used to quantify lacunar infarcts, white matter hyperintensities, CMBs, and medial temporal lobe atrophy. Eighty-two of the 85 patients completed the assessment for dementia conversion at a 1-year follow-up assessment. Multivariate logistic regression analyses were conducted to examine independent clinical and MRI variables associated with dementia conversion. Twenty-four patients(29.3%) had converted to dementia at the 1-year follow-up, and these individuals had significantly more CMBs in the fronto-subcortical circuits. Multivariate logistic regression analyses revealed that the patients with CMBs in the fronto-subcortical circuits(odds ratio = 4.4; 95% confidence interval: 1.602-12.081, P = 0.004) and 5 or more CMBs overall(odds ratio = 17.6, 95% confidence interval: 3.23-95.84, P = 0.001) had a significantly increased risk of dementia at the 1-year follow-up. These findings indicate that CMBs in the fronto-subcortical circuits may be predictive of dementia conversion in CSVD patients with V-CIND, and thus extend the clinical significance of CMBs.
基金supported by the National Key Research and Development Program of China(No.2016YFA0401902)
文摘We demonstrated a novel method to measure the unloaded quality factor(Q factor) of high-Q resonant cavities. This method was used to obtain data with low errors and calculate the unloaded Q factor. This procedure was more reliable than traditional methods. The data required for the method were near the resonant frequency,not at the half-power points of the reflection coefficient curve or Smith chart. We applied the new method to measure a resonant cavity with an unloaded Q factor of^100,000, obtaining good agreement between the measured and theoretical results.
文摘A full planar tunable band pass resonator is introduced, which is constructed by using novel symmetric step impedance resonator (SIR) and hyperabrupt varactors for wide bandwidth tuning and size reduction. The equivalent circuit model of the proposed resonator is set up. Theoretical analysis based on transmission line as well as odd and even-mode method is completed. The attractiveness of the approach presented lies in its simplicity. Based on the detailed analysis, a 6 GHz to 10 GHz varactor tuned resonator is designed, fabricated, and measured. It shows wideband tuning ability of 37%. The experimental results of the resonator have a good agreement with the analysis results.
基金Project supported by the National Natural Science Foundation of China(Grant No.61405082)the Fundamental Research Funds for the Central Universities
文摘In this paper, we design and fabricate a silicon integrated optical filter consisting of two cascaded micro-ring resonators and two straight waveguides. Two micro-heaters are fabricated on the top of two micro-rings respectively, which are employed to modulate the micro-rings to perform the function of a tunable optical filter by the thermo–optic effect. The static response test indicates that the extinction ratio and 3-d B bandwidth are 29.01 d B and 0.21 nm respectively, the dynamic response test indicates that the 10%–90% rise and 90%–10% fall time of the filter are 16 μs and 12 μs, respectively,which can meet the requirements of optical communication and information processing. Finally, the power consumption of the device is also characterized, and the total power consumption is about 9.43 m W/nm, which has been improved efficiently.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61222110 and 60971073)
文摘A theoretical model is developed for calculating the eigenmodes of the multi-gap resonant cavity. The structure of concern is a kind of ladder-type circuit, offering the advantages of easy fabrication, high characteristic impedance (R/Q), and thermal capacity in the millimeter wave to THz regime. The eigenfunction expansion method is used to establish the field expressions for the gaps and the coupling region. Then, the match conditions at the interface are employed, which leads to a group of complicate boundary equations in the form of an infinite series. To facilitate the mathematical treatments and perform a highly efficient calculation, these boundary equations are transformed into the algebraic forms through the matrix representations. Finally, the concise dispersion equation is obtained. The roots of the dispersion equation include both the axial modes in the gaps, which include the fundamental and the high-order modes, and the cavity modes in the coupling region. Extensive numerical results are presented and the behaviors of the multi-gap resonant cavity are examined.
基金Project supported by the FAPEG (CV)INCT-IQ (ATA)the CNPq (ATA,BB)
文摘We propose a scheme to transmit information via the statistical distribution of excitations of a nanomechanical resonator. It employs a controllable coupling between this system and a Cooper pair box. The success probability and the fidelity are calculated and compared with those obtained in an atom-field system in different regimes. Addtionaly, the scheme can also be applied to prepare low excited Fock states.
文摘Recently, resonant AC/DC converter has been accepted by the industry. However, the efficiency will be decreased at light load. So, a novel topology with critical controlling mode combined with resonant ones is proposed in this paper. The new topology can correspond to a 90 plus percent of power converting. So,a novel topology of an state of-art integrated circuit, which can be used as power management circuit, has been designed based on the above new topology. A simulator which is specific suitable for the power controller has been founded in this work and it has been used for the simulation of the novel architecture and the proposed integrated circuit.
文摘Once people have a well-trained motor skill, their performance becomes stabilized and achieving substantial improvement is difficult. Recently, we have shown that even a plateaued hand motor skill can be upgraded with short-period electrical stimulation to the hand prior to the task. Here, we identify the neuronal substrates underlying the improvement of the plateaued skill by examining the enhanced functional connectivity in the sensory-motor regions that are associated with motor learning. We measured brain activity using functional magnetic resonance imaging and performed psychophysiological interaction analysis. We recruited seven right-handed very-well trained participants, whose motor performance of continuously rotating two balls with their right hands became stabilized at higher performance levels. We prepared two experiments, in each of which they repeated an experimental run 16 times. In each run, they performed this cyclic rotation as many times as possible in 16 s. In the thenar-stimulation experiment, we applied 60-s stimulation to the thenar muscle before each of the 5th - 12th runs, and the others were preceded by ineffective sham stimulation. In the control experiment, the sham was always provided. Thenar stimulation enabled the participants to perform the movements at higher cycles. In association with this performance improvement, we found enhanced activity couplings between the primary motor cortex and the sensorimotor territory of the putamen and between the cerebellum and the primary sensorimotor cortices, without any quantitative activity increase. Neither behavioral change nor these increased activity couplings were observed in the control.Thus, in contrast to the stable neuronal states in the cortico-subcortical motor circuits when the well-learned task is repeated at the later stages of motor skill learning, plastic changes in the motor circuits seem to be required when the plateaued skill is upgraded, and the stimulation may entail a state of readiness for the plastic change that allows subsequent performance improvement.
基金SUPPORTED BY NATIONAL NATURAL SCIENCE FOUNDATION OF CHINA( NO. 60177010).
文摘Resonant tunneling diode (RTD) of AlAs/InGaAs/AlAs double barrier-single well structure was designed and fabricated. The devices showed current-voltage characteristics with peak-valley current ratio of 4 : 1 at room temperature. The scattering parameter of RTD was measured by using an HP8510(C) network analyzer. Equivalent circuit parameters were obtained by curve fitting and optimized. The RTD switching time was estimated using the measured capacitance and average negative differential resistance. The minimum rise time of the sample was estimated to be 21 ps.
基金supported by Program for New Century Excellent Talents in University(NCET)(2008)Funding Project for Academic Human Resources Development in Institutions of Higher Learning Under the Jurisdiction of Beijing Municipality+1 种基金 (PHR(IHLB)) and Beijing Novel Research Star(2005B01)Ministry of Beijing Science and Technology
文摘Recently, resonant AC/DC converter has been accepted by the industry. However, the efficiency will be decreased at light load. So, a novel topology with critical controlling mode combined with resonant ones is proposed in this paper. The new topology can correspond to a 90 plus percent of power converting. So,a novel topology of an state of art integrated circuit, which can be used as power management circuit, has been designed based on the above new topology. A simulator which is specifically suitable for the power controller has been founded in this work and it has been used for the simulation of the novel architecture and the proposed integrated circuit.
文摘The zero-voltage quasi-resonant boost switching DC-DC converter has been inves-tigated by using the time averaging equivalent circuit approach of periodically switching linearnetworks.The DC steady state and AC small signal characteristics of the converter are also given.