Background Nursery pigs undergo stressors in the post-weaning period that result in production and welfare chal-lenges.These challenges disproportionately impact the offspring of primiparous sows compared to those of ...Background Nursery pigs undergo stressors in the post-weaning period that result in production and welfare chal-lenges.These challenges disproportionately impact the offspring of primiparous sows compared to those of mul-tiparous counterparts.Little is known regarding potential interactions between parity and feed additives in the post-weaning period and their effects on nursery pig microbiomes.Therefore,the objective of this study was to investigate the effects of maternal parity on sow and offspring microbiomes and the influence of sow parity on pig fecal microbi-ome and performance in response to a prebiotic post-weaning.At weaning,piglets were allotted into three treat-ment groups:a standard nursery diet including pharmacological doses of Zn and Cu(Con),a group fed a commercial prebiotic only(Preb)based on an Aspergillus oryzae fermentation extract,and a group fed the same prebiotic plus Zn and Cu(Preb+ZnCu).Results Although there were no differences in vaginal microbiome composition between primiparous and mul-tiparous sows,fecal microbiome composition was different(R^(2)=0.02,P=0.03).The fecal microbiomes of primiparous offspring displayed significantly higher bacterial diversity compared to multiparous offspring at d 0 and d 21 post-weaning(P<0.01),with differences in community composition observed at d 21(R^(2)=0.03,P=0.04).When analyzing the effects of maternal parity within each treatment,only the Preb diet triggered significant microbiome distinc-tions between primiparous and multiparous offspring(d 21:R^(2)=0.13,P=0.01;d 42:R^(2)=0.19,P=0.001).Composi-tional differences in pig fecal microbiomes between treatments were observed only at d 21(R^(2)=0.12,P=0.001).Pigs in the Con group gained significantly more weight throughout the nursery period when compared to those in the Preb+ZnCu group.Conclusions Nursery pig gut microbiome composition was influenced by supplementation with an Aspergillus oryzae fermentation extract,with varying effects on performance when combined with pharmacological levels of Zn and Cu or for offspring of different maternal parity groups.These results indicate that the development of nursery pig gut microbiomes is shaped by maternal parity and potential interactions with the effects of dietary feed additives.展开更多
Background Fertility declines in high-parity sows.This study investigated whether parity-dependent declines in embryonic survival and reproductive performance could be restored by dietary coenzyme Q10(CoQ10)supplement...Background Fertility declines in high-parity sows.This study investigated whether parity-dependent declines in embryonic survival and reproductive performance could be restored by dietary coenzyme Q10(CoQ10)supplementation.Methods Two experiments were performed.In Exp.1,30 young sows that had completed their 2nd parity and 30 high-parity sows that had completed their 10^(th)parity,were fed either a control diet(CON)or a CON diet supple-mented with 1 g/kg CoQ10(+CoQ10)from mating until slaughter at day 28 of gestation.In Exp.2,a total of 314 post-weaning sows with two to nine parities were fed the CON or+CoQ10 diets from mating throughout gestation.Results In Exp.1,both young and high-parity sows had a similar number of corpora lutea,but high-parity sows had lower plasma CoQ10 concentrations,down-regulated genes involved with de novo CoQ10 synthesis in the endome-trium tissues,and greater levels of oxidative stress markers in plasma and endometrium tissues.High-parity sows had fewer total embryos and alive embryos,lower embryonic survival,and greater embryo mortality than young sows.Dietary CoQ10 supplementation increased the number of live embryos and the embryonic survival rate to levels simi-lar to those of young sows,as well as lowering the levels of oxidative stress markers.In Exp.2,sows showed a parity-dependent decline in plasma CoQ10 levels,and sows with more than four parities showed a progressive decline in the number of total births,live births,and piglets born effective.Dietary supplementation with CoQ10 increased the number of total births,live births,and born effective,and decreased the intra-litter covariation coefficients and the percentage of sows requiring farrowing assistance during parturition.Conclusions Dietary CoQ10 supplementation can improve the embryonic survival and reproductive performance of gestating sows with high parity,probably by improving the development of uterine function.展开更多
利用变量节点符号可靠度在迭代过程中的分布特征,提出了一种基于可靠度差值特征的自适应判决多元低密度奇偶校验(Low Density Parity Check, LDPC)译码算法。整个迭代过程划分为两个阶段,针对不同阶段节点可靠度的差值特征分别采用不同...利用变量节点符号可靠度在迭代过程中的分布特征,提出了一种基于可靠度差值特征的自适应判决多元低密度奇偶校验(Low Density Parity Check, LDPC)译码算法。整个迭代过程划分为两个阶段,针对不同阶段节点可靠度的差值特征分别采用不同的判决策略:前期阶段,采用传统的基于最大可靠度的判决策略;后期阶段,根据最大、次大可靠度之间的差值特征,设计自适应的码元符号判决策略。仿真结果表明,所提算法在相当的译码复杂度前提下,能获得0.15~0.4 dB的性能增益。同时,对于列重较小的LDPC码,具有更低的译码错误平层。展开更多
军事卫星通信由于需满足信息实时性、传输速率高、通信容量大以及符合星间链路信道的时变特性等要求,通常采用高编码增益、高吞吐量的信道编码方案。低密度奇偶校验(Low-Density Parity-Check,LDPC)码由于具备接近Shannon极限的优异纠...军事卫星通信由于需满足信息实时性、传输速率高、通信容量大以及符合星间链路信道的时变特性等要求,通常采用高编码增益、高吞吐量的信道编码方案。低密度奇偶校验(Low-Density Parity-Check,LDPC)码由于具备接近Shannon极限的优异纠错性能和可并行计算的特性成为卫星通信主导信道编码标准之一。目前卫星通信接收机的译码器模块设计仍存在诸如无法实时在线判断迭代停止、系统吞吐量受限、大量判决电路影响核心译码电路的低功耗和实时性等问题。考虑上述问题,以因子图模型为基础,针对空间数据系统咨询委员会(Consultative Committee for Space Data Systems,CCSDS)标准深空通信码型,将校验节点归一化满足概率进化图案与LDPC译码器状态紧密耦合,给出可实时在线判断迭代停止的最优停止准则,实现高性能、低复杂度的停止准则译码算法设计。当优先考虑高吞吐量时,误码率(Bit Error Rate,BER)性能退化0.13 dB,中低信噪比平均迭代次数(Average Number of Iteration,ANI)降低50%以上;当优先考虑纠错性能时,BER性能仅退化0.02 dB,同时大幅降低ANI。该译码算法为高效低复杂度LDPC译码器设计提供有效解决方案。展开更多
基金This study was partially supported by funds from the Agricultural Research,Education,Extension and Technology Transfer(AGREETT)and MNDrive Global Food Ventures Programs,both from the University of MinnesotaPartial funding was supplied by BioZyme,Inc,St.Joseph,Missouri,USA and New Fashion Pork,Jackson,MN,USA.
文摘Background Nursery pigs undergo stressors in the post-weaning period that result in production and welfare chal-lenges.These challenges disproportionately impact the offspring of primiparous sows compared to those of mul-tiparous counterparts.Little is known regarding potential interactions between parity and feed additives in the post-weaning period and their effects on nursery pig microbiomes.Therefore,the objective of this study was to investigate the effects of maternal parity on sow and offspring microbiomes and the influence of sow parity on pig fecal microbi-ome and performance in response to a prebiotic post-weaning.At weaning,piglets were allotted into three treat-ment groups:a standard nursery diet including pharmacological doses of Zn and Cu(Con),a group fed a commercial prebiotic only(Preb)based on an Aspergillus oryzae fermentation extract,and a group fed the same prebiotic plus Zn and Cu(Preb+ZnCu).Results Although there were no differences in vaginal microbiome composition between primiparous and mul-tiparous sows,fecal microbiome composition was different(R^(2)=0.02,P=0.03).The fecal microbiomes of primiparous offspring displayed significantly higher bacterial diversity compared to multiparous offspring at d 0 and d 21 post-weaning(P<0.01),with differences in community composition observed at d 21(R^(2)=0.03,P=0.04).When analyzing the effects of maternal parity within each treatment,only the Preb diet triggered significant microbiome distinc-tions between primiparous and multiparous offspring(d 21:R^(2)=0.13,P=0.01;d 42:R^(2)=0.19,P=0.001).Composi-tional differences in pig fecal microbiomes between treatments were observed only at d 21(R^(2)=0.12,P=0.001).Pigs in the Con group gained significantly more weight throughout the nursery period when compared to those in the Preb+ZnCu group.Conclusions Nursery pig gut microbiome composition was influenced by supplementation with an Aspergillus oryzae fermentation extract,with varying effects on performance when combined with pharmacological levels of Zn and Cu or for offspring of different maternal parity groups.These results indicate that the development of nursery pig gut microbiomes is shaped by maternal parity and potential interactions with the effects of dietary feed additives.
基金supported by the National Key Research and Development Program of China(2022YFD1301300).
文摘Background Fertility declines in high-parity sows.This study investigated whether parity-dependent declines in embryonic survival and reproductive performance could be restored by dietary coenzyme Q10(CoQ10)supplementation.Methods Two experiments were performed.In Exp.1,30 young sows that had completed their 2nd parity and 30 high-parity sows that had completed their 10^(th)parity,were fed either a control diet(CON)or a CON diet supple-mented with 1 g/kg CoQ10(+CoQ10)from mating until slaughter at day 28 of gestation.In Exp.2,a total of 314 post-weaning sows with two to nine parities were fed the CON or+CoQ10 diets from mating throughout gestation.Results In Exp.1,both young and high-parity sows had a similar number of corpora lutea,but high-parity sows had lower plasma CoQ10 concentrations,down-regulated genes involved with de novo CoQ10 synthesis in the endome-trium tissues,and greater levels of oxidative stress markers in plasma and endometrium tissues.High-parity sows had fewer total embryos and alive embryos,lower embryonic survival,and greater embryo mortality than young sows.Dietary CoQ10 supplementation increased the number of live embryos and the embryonic survival rate to levels simi-lar to those of young sows,as well as lowering the levels of oxidative stress markers.In Exp.2,sows showed a parity-dependent decline in plasma CoQ10 levels,and sows with more than four parities showed a progressive decline in the number of total births,live births,and piglets born effective.Dietary supplementation with CoQ10 increased the number of total births,live births,and born effective,and decreased the intra-litter covariation coefficients and the percentage of sows requiring farrowing assistance during parturition.Conclusions Dietary CoQ10 supplementation can improve the embryonic survival and reproductive performance of gestating sows with high parity,probably by improving the development of uterine function.
文摘军事卫星通信由于需满足信息实时性、传输速率高、通信容量大以及符合星间链路信道的时变特性等要求,通常采用高编码增益、高吞吐量的信道编码方案。低密度奇偶校验(Low-Density Parity-Check,LDPC)码由于具备接近Shannon极限的优异纠错性能和可并行计算的特性成为卫星通信主导信道编码标准之一。目前卫星通信接收机的译码器模块设计仍存在诸如无法实时在线判断迭代停止、系统吞吐量受限、大量判决电路影响核心译码电路的低功耗和实时性等问题。考虑上述问题,以因子图模型为基础,针对空间数据系统咨询委员会(Consultative Committee for Space Data Systems,CCSDS)标准深空通信码型,将校验节点归一化满足概率进化图案与LDPC译码器状态紧密耦合,给出可实时在线判断迭代停止的最优停止准则,实现高性能、低复杂度的停止准则译码算法设计。当优先考虑高吞吐量时,误码率(Bit Error Rate,BER)性能退化0.13 dB,中低信噪比平均迭代次数(Average Number of Iteration,ANI)降低50%以上;当优先考虑纠错性能时,BER性能仅退化0.02 dB,同时大幅降低ANI。该译码算法为高效低复杂度LDPC译码器设计提供有效解决方案。
