The purpose of this experiment is to investigate the effect of pulsed electromagnetic field (PEMF) and biomechanical force on orthodontic tooth movement by means of measurement of gross tooth movement anatomic data, l...The purpose of this experiment is to investigate the effect of pulsed electromagnetic field (PEMF) and biomechanical force on orthodontic tooth movement by means of measurement of gross tooth movement anatomic data, light microscopic evaluation and transmission electromicroscopic evaluation. The results indicate that PEMF combined with biomechanical force could accelerate the rate and amount of orthodontic tooth movement, enhance bone deposition in tension side and resorption in compression side. The results also suggest that PEMF could accelerate orthodontic tooth movement as a result of increase in quantity of active cells, PEMF couldn’t change the ultrastructure of cells.展开更多
目的 探讨旋转脉动磁场对兔实验性牙齿移动过程中牙周组织血小板衍生生长因子A（PDGF-A）表达的影响.方法 30只体重为1.0～1.5 kg的健康新西兰大耳白兔按每组5只随机分为实验1、3、5、7、14、21 d组.2%戊巴比妥钠麻醉下于双侧上颌第一...目的 探讨旋转脉动磁场对兔实验性牙齿移动过程中牙周组织血小板衍生生长因子A（PDGF-A）表达的影响.方法 30只体重为1.0～1.5 kg的健康新西兰大耳白兔按每组5只随机分为实验1、3、5、7、14、21 d组.2%戊巴比妥钠麻醉下于双侧上颌第一磨牙与切牙间拴结不锈钢螺簧,施力80g,左侧只加力为对照侧,右侧加力加旋转脉动磁场为实验侧,通过免疫组织化学染色进行PDGF-A半定量分析.结果 实验侧牙周组织中PDGF-A表达高于对照侧;实验侧张力区、压力区牙周组织中PDGF-A表达在5、7、14 d时较对照侧差异有统计学意义（5.28±0.14 vs 2.03±0.18,7.63±0.27 vs 2.84±0.12,3.52±0.16 vs 1.65±0.03;8.10±0.13 vs 4.30±0.21,13.27±0.31 vs 6.47±0.15,5.66±0.22 vs 3.15±0.27,P＜0.05）;在7 d时牙周组织PDGF-A表达达到高峰.结论 旋转脉动磁场照射促进了牙周组织中PDGF-A的表达,促进了牙周组织的改建.展开更多
文摘The purpose of this experiment is to investigate the effect of pulsed electromagnetic field (PEMF) and biomechanical force on orthodontic tooth movement by means of measurement of gross tooth movement anatomic data, light microscopic evaluation and transmission electromicroscopic evaluation. The results indicate that PEMF combined with biomechanical force could accelerate the rate and amount of orthodontic tooth movement, enhance bone deposition in tension side and resorption in compression side. The results also suggest that PEMF could accelerate orthodontic tooth movement as a result of increase in quantity of active cells, PEMF couldn’t change the ultrastructure of cells.
文摘目的 探讨旋转脉动磁场对兔实验性牙齿移动过程中牙周组织血小板衍生生长因子A（PDGF-A）表达的影响.方法 30只体重为1.0～1.5 kg的健康新西兰大耳白兔按每组5只随机分为实验1、3、5、7、14、21 d组.2%戊巴比妥钠麻醉下于双侧上颌第一磨牙与切牙间拴结不锈钢螺簧,施力80g,左侧只加力为对照侧,右侧加力加旋转脉动磁场为实验侧,通过免疫组织化学染色进行PDGF-A半定量分析.结果 实验侧牙周组织中PDGF-A表达高于对照侧;实验侧张力区、压力区牙周组织中PDGF-A表达在5、7、14 d时较对照侧差异有统计学意义（5.28±0.14 vs 2.03±0.18,7.63±0.27 vs 2.84±0.12,3.52±0.16 vs 1.65±0.03;8.10±0.13 vs 4.30±0.21,13.27±0.31 vs 6.47±0.15,5.66±0.22 vs 3.15±0.27,P＜0.05）;在7 d时牙周组织PDGF-A表达达到高峰.结论 旋转脉动磁场照射促进了牙周组织中PDGF-A的表达,促进了牙周组织的改建.
