Introduction The cyano branched carbohydrates are useful, versatil intermediaries for the synthesis of branched sugars having biological activity in nature. Owing to the good yield, mild reaction conditions and high s...Introduction The cyano branched carbohydrates are useful, versatil intermediaries for the synthesis of branched sugars having biological activity in nature. Owing to the good yield, mild reaction conditions and high stereospecificity, the phase transition catalysis(PTC)method has been widely used to the syntheses of C-展开更多
Great attention has been paid to the synthesis and structural analysis of 1, 3-anhydro-pyranose derivatives since B. Samuelsson reported the structure and strong biological activities of Thromboxane A<sub>2</...Great attention has been paid to the synthesis and structural analysis of 1, 3-anhydro-pyranose derivatives since B. Samuelsson reported the structure and strong biological activities of Thromboxane A<sub>2</sub>（TXA<sub>2</sub>） for platelet aggregation, vasoconstriction and contraction of smooth muscle in 1975. The nucleus of 2, 6-dioxabicyclo [3,1,1] heptane has been considered to play an important role in the strong bioactiv ities of TXA<sub>2</sub>. It is difficult to investigate the molecular structure of TXA<sub>2</sub>展开更多
基金Supported by the National Natural Science Foundation of China
文摘Introduction The cyano branched carbohydrates are useful, versatil intermediaries for the synthesis of branched sugars having biological activity in nature. Owing to the good yield, mild reaction conditions and high stereospecificity, the phase transition catalysis(PTC)method has been widely used to the syntheses of C-
基金Project supported by the National Natural Science Foundation of China.
文摘Great attention has been paid to the synthesis and structural analysis of 1, 3-anhydro-pyranose derivatives since B. Samuelsson reported the structure and strong biological activities of Thromboxane A<sub>2</sub>（TXA<sub>2</sub>） for platelet aggregation, vasoconstriction and contraction of smooth muscle in 1975. The nucleus of 2, 6-dioxabicyclo [3,1,1] heptane has been considered to play an important role in the strong bioactiv ities of TXA<sub>2</sub>. It is difficult to investigate the molecular structure of TXA<sub>2</sub>
