The crystal structure of 2-methylthio-3-cyano-7-（4-methoxyphenyl）-pyrazolo[1,5- a]-pyrimidine （C15H12N4OS, Mr = 296.35） has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to mono...The crystal structure of 2-methylthio-3-cyano-7-（4-methoxyphenyl）-pyrazolo[1,5- a]-pyrimidine （C15H12N4OS, Mr = 296.35） has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to monoclinic, space group P21/c with a = 9.200（3）, b = 15.570（5）, c = 11.125（4） A,β= 114.273（6）°, V= 1452.7（8） A^3, Z= 4, De= 1.355 g/cm^3, μ= 0.227 mm^-1, F（000） = 616, R = 0.0499 and wR = 0.0949 for 2947 unique reflections with 1633 observed ones （I 〉 2σ（I））. The results show that all ring atoms in the pyrazolopyrimidine moiety are almost coplanar with a strong tensile force, which might be an important active site. The preliminary biological test shows that the title compound has moderate herbicidal activities.展开更多
Fifteen N'-(substituted pyrimidin-2-y1)-N-substituted phenoxyacetyl thioureas were synthesized and tested for biological activities. All of them are new compounds and their structures were confirmed by IR. IHNMR. ...Fifteen N'-(substituted pyrimidin-2-y1)-N-substituted phenoxyacetyl thioureas were synthesized and tested for biological activities. All of them are new compounds and their structures were confirmed by IR. IHNMR. MS and elemental analysis. Some of the target compounds showed excellent inhibitory activities against root and stalk of dicotyledon plant (such as radish). and selective on monoctyledon plant (such as rice).展开更多
Four -N--(substituted-pyrimidin-2-yl)--N--2-chloro-phenoxyacetyl thioureas 2 were synthesized through the reactions of 2-chloro-phenoxyacetyl isothiocyanate with substituted-2-amino-pyrimidines.Four 2-H--1,2,4-thiad...Four -N--(substituted-pyrimidin-2-yl)--N--2-chloro-phenoxyacetyl thioureas 2 were synthesized through the reactions of 2-chloro-phenoxyacetyl isothiocyanate with substituted-2-amino-pyrimidines.Four 2-H--1,2,4-thiadiazolo[2,3--a-]pyrimidine dervatives were synthesized by the oxidizing cyclizations of 2. All of them are new compounds. Their structures were confirmed by IR, 1HNMR and elementary analysis.The preliminary herbicidal test showed that some of them have excellent inhibitory activities against root and stalk of dicotyledon plant, but selective to monocotyledon plant.展开更多
Five novel cis-3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropyl formyl thiourea derivatives(4a～4e) have been synthesized. Their structures are characterized by 1H NMR, IR and elemental analysis. The preli...Five novel cis-3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropyl formyl thiourea derivatives(4a～4e) have been synthesized. Their structures are characterized by 1H NMR, IR and elemental analysis. The preliminary herbicidal tests indicate the compound 4a shows a better inhibitory activity to broad leaf plant, 4d and 4e to monoctyledon plant, respectively.展开更多
文摘The crystal structure of 2-methylthio-3-cyano-7-（4-methoxyphenyl）-pyrazolo[1,5- a]-pyrimidine （C15H12N4OS, Mr = 296.35） has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to monoclinic, space group P21/c with a = 9.200（3）, b = 15.570（5）, c = 11.125（4） A,β= 114.273（6）°, V= 1452.7（8） A^3, Z= 4, De= 1.355 g/cm^3, μ= 0.227 mm^-1, F（000） = 616, R = 0.0499 and wR = 0.0949 for 2947 unique reflections with 1633 observed ones （I 〉 2σ（I））. The results show that all ring atoms in the pyrazolopyrimidine moiety are almost coplanar with a strong tensile force, which might be an important active site. The preliminary biological test shows that the title compound has moderate herbicidal activities.
文摘Fifteen N'-(substituted pyrimidin-2-y1)-N-substituted phenoxyacetyl thioureas were synthesized and tested for biological activities. All of them are new compounds and their structures were confirmed by IR. IHNMR. MS and elemental analysis. Some of the target compounds showed excellent inhibitory activities against root and stalk of dicotyledon plant (such as radish). and selective on monoctyledon plant (such as rice).
文摘Four -N--(substituted-pyrimidin-2-yl)--N--2-chloro-phenoxyacetyl thioureas 2 were synthesized through the reactions of 2-chloro-phenoxyacetyl isothiocyanate with substituted-2-amino-pyrimidines.Four 2-H--1,2,4-thiadiazolo[2,3--a-]pyrimidine dervatives were synthesized by the oxidizing cyclizations of 2. All of them are new compounds. Their structures were confirmed by IR, 1HNMR and elementary analysis.The preliminary herbicidal test showed that some of them have excellent inhibitory activities against root and stalk of dicotyledon plant, but selective to monocotyledon plant.
文摘Five novel cis-3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropyl formyl thiourea derivatives(4a～4e) have been synthesized. Their structures are characterized by 1H NMR, IR and elemental analysis. The preliminary herbicidal tests indicate the compound 4a shows a better inhibitory activity to broad leaf plant, 4d and 4e to monoctyledon plant, respectively.
