The Application of Quality Control Circles to Reduce the Cost of Non-priced Consumables in Department of Oncology

Objective:To investigate the effectiveness of using quality control circle(QCC)techniques to reduce the cost of non-priced consumables in medical oncology.Methods:Analytic statistics were compiled on the performance appraisal form.Aiming at the key points of improvement with respect to the excess cost of non-valuable consumables,the reasons were analyzed,and corresponding measures were formulated to compare the cost before and after the improvement.Results:After the QCC activity,the cost of non-priced consumables decreased from RMB 6.57/bed day to RMB 3.96/bed day.Conclusion:QCC has effectively reduced the cost of non-priced consumables in the oncology department,and it is worthy of promotion.

The Theory and Methods Research on Ecological Quality Control of Enterprises

So far, most theories of economics and management are under the same premisethat the natural resources are never exhausted and regenerated repeatedly. The magic of technologybrought by industrial revolution endowed human with power that they can do anything they want. Italso turns natural resources into industrial energy and enhances the development of human societyand civilization. Human uses direct comparison of input and output and the satisfaction degree ofdemands to measure the production activities, the economic benefit and management performance,regardless of the change of ecology that serves as the natural resources. However, since theecological environment has been changing worse recently and natural disaster happened frequentlyhuman's dream of conquering the nature has been broken. The nature implements reprisal against humanagain and again, and human is faced with the development limit because of the environmentalrestriction.

Quality Control and Nonclinical Research on CAR-T Cell Products: General Principles and Key Issues

Adoptive cell therapy using chimeric antigen receptor T (CAR-T) cells, which is a promising cancer immunotherapy strategy, has been developing very rapidly in recent years. CAR-T cells are genetically modified T cells that can specifically recognize tumor specific antigens on the surface of tumor cells, and then effectively kill tumor cells. At present, exciting results are being achieved in clinical applications of CAR-T cells for patients with hematological malignancies. The research and development of CAR-T cells for various targets and for the treatment of solid tumors have become a hot topic worldwide, so an increasing number of investigational new drug applications (INDAs) and new drug applications (NDAs) of CAR-T cell products are expected to be submitted in future. The quality control and nonclinical research of these products are of great significance in ensuring the safety and effectiveness of these products;however, they also present great challenges and difficulties. This article discusses the general principles of and key issues regarding the quality control and nonclinical research of CAR-T cell products based on their product characteristics and on relevant guidelines for gene and cell therapy products.

Study on Rear-end Real-time Data Quality Control Method of Regional Automatic Weather Station

[Objective] The aim was to study the rear-end real-time data quality control method of regional automatic weather station. [Method] The basic content and steps of rear-end real-time data quality control of regional automatic weather station were introduced. Each element was treated with systematic quality control procedure. The existence of rear-end real time data of regional meteorological station in Guangxi was expounded. Combining with relevant elements and linear changes, improvement based on traditional quality control method was made. By dint of evaluation and relevant check of element, the quality of temperature and pressure was controlled. [Result] The method was optimized based on traditional quality control method, and it narrowed the effectiveness of real-time data quality control. The quality check of hourly precipitation applied relevant check of hourly minimum temperature, vertical consistency check of radar data, which can effectively improve the accuracy and credibility of hourly precipitation quality control. [Conclusion] The method was on trial for one year in the quality control of real-time data in the regional automatic meteorological station in Guangxi and had gained good outcome.

VPLS Based Quality and Cost Control for Tennessee Eastman Process

Product quality and operation cost control obtain increasing emphases in modern chemical system engineering. To improve the fault detection power of the partial least square (PLS) method for quality control, a new QRPV statistic is proposed in terms of the VP (variable importance in projection) indices of monitored process variables, which is significantly advanced over and different from the conventional Q statistic. QRPV is calculated only by the residuals of the remarkable process variables (RPVs). Therefore, it is the dominant relation between quality and RPV not all process variables (as in the case of the conventional PLS) that is monitored by this new VP-PLS (VPLS) method. The combination of QRPV and T2 statistics is applied to the quality and cost control of the Tennessee Eastman (TE) process, and weak faults can be detected as quickly as possible. Consequently, the product quality of TE process is guaranteed and operation costs are reduced.

Cost Control research in Construction Project Management

Construction project management as an important branch of management science has its own characteristics; it was known as an important aspect of project management in the 21 st century. Construction companies now face a more complex competitive environment and more powerful competitors. In order to compete for the market and living space, Enterprises should be in a strategic height, cultivate long- term competitive advantage. Cost management is a new tool to enhance the competitiveness of enterprises, Popularization and application of Construction project management to the scientific development of the project management made the following three aspects urgent requirement. First. establish a scientific system for the construction project management. Construction Project Management knowledge system is the foundation and needs for Construction Project Management scientific and professional.

Memory-Type Control Charts Through the Lens of Cost Parameters

A memory-type control chart utilizes previous information for chart construction.An example of a memory-type chart is an exponentially-weighted moving average(EWMA)control chart.The EWMA control chart is well-known and widely employed by practitioners for monitoring small and moderate process mean shifts.Meanwhile,the EWMA median chart is robust against outliers.In light of this,the economic model of the EWMA and EWMA median control charts are commonly considered.This study aims to investigate the effect of cost parameters on the out-of-control average run lengthðARL_(1)Þin implementing EWMA and EWMA median control charts.The economic model was used to compute the ARL_(1) parameter.The 14 input parameters were identified and the analysis was carried out based on the one-parameter-at-a-time basis.When the input parameters change based on a predetermined percentage,the ARL_(1) is affected.According to the results of the EWMA chart,nine input parameters had an effect andfive input parameters had no effect on the ARL_(1) parameter.Further,only seven of the 14 input parameters had an effect on the ARL_(1) of the EWMA median chart.However,the effect of each input parameter on the ARL_(1) was different.Moreover,the ARL_(1) for the EWMA median chart was smaller than the EWMA chart.This analysis is crucial to observe and determine the input parameters that have a significant impact on the ARL_(1) of the EMWA and EWMA median control charts.Hence,practitioners can obtain an overview of the influence of the input parameters on the ARL_(1) when implementing the EWMA and EWMA median control charts.

The Impact of Health Care Reform Initiatives on Ethical Conflict and Opportunities for Nurses to Improve Quality of Care While Enhancing Their Work Environments

Background: After more than a decade of the nursing profession contending that healthcare reform based almost exclusively on cost cutting was creating an array of serious ethical issues for nurses, healthcare organizations and other providers are now facing increasing demands primarily from payers to demonstrate improvement in both quality of care and patient experience along with continued cost reduction. Research Question: Have efforts by healthcare organizations to comply with these recently imposed requirements influenced the ethical environment faced by nurses and nurse leaders and if so, how? Materials and Methods: Data for assessing the current ethical environment was gathered with a close-ended survey mailed in October 2012 to a random sample of 3000 members of the American Organization of Nurse Executives. Results and Discussion: Statistical analysis of the data and comparison with the findings of a similar study conducted in 2000 indicated that along with five highly rated issues in the earlier study attributed largely to economic constraints imposed by healthcare organizations, the top-10 key ethical issues today included five issues primarily attributable to interprofessional conflict. Conclusion: Given the success of many ongoing efforts aimed at weakening these key sources of ethical conflict that have blocked many proposals to improve the quality of care, opportunities should arise for the nursing profession to more fully achieve its goals of improving the quality of care, safety and patient satisfaction and enhancing nurses’ work environments essential to that effort.

A Clustering-tree Topology Control Based on the Energy Forecast for Heterogeneous Wireless Sensor Networks

How to design an energy-efficient algorithm to maximize the network lifetime in complicated scenarios is a critical problem for heterogeneous wireless sensor networks (HWSN). In this paper, a clustering-tree topology control algorithm based on the energy forecast (CTEF) is proposed for saving energy and ensuring network load balancing, while considering the link quality, packet loss rate, etc. In CTEF, the average energy of the network is accurately predicted per round (the lifetime of the network is denoted by rounds) in terms of the difference between the ideal and actual average residual energy using central limit theorem and normal distribution mechanism, simultaneously. On this basis, cluster heads are selected by cost function (including the energy, link quality and packet loss rate) and their distance. The non-cluster heads are determined to join the cluster through the energy, distance and link quality. Furthermore, several non-cluster heads in each cluster are chosen as the relay nodes for transmitting data through multi-hop communication to decrease the load of each cluster-head and prolong the lifetime of the network. The simulation results show the efficiency of CTEF. Compared with low-energy adaptive clustering hierarchy (LEACH), energy dissipation forecast and clustering management (EDFCM) and efficient and dynamic clustering scheme (EDCS) protocols, CTEF has longer network lifetime and receives more data packets at base station. © 2014 Chinese Association of Automation.

Added Value of Power Control in Improving the Integration of Wind Turbines in Weak Grid Conditions

For economical reasons, wind turbine systems must be located in favourable sites generating a higher pro- ductivity. These are often located in areas with weak electric grid infrastructures. The constraints related to this type of grids limit the penetration levels of wind energy. These constraints are mainly related to power quality in the grid as well as the economical aspects of the project. In this study, we take into account the slow voltage variations and the flicker phenomenon. The models used are based on the development of a set of relations derived from engineering knowledge related to both technical and economical points of view. The maximal penetration level of a fixed speed wind turbine system is determined for a given grid. The power control has been investigated to improve wind turbine system integration. Obtained results show the necessity to adapt technological choices to the requirements of weaker grids. Penetration levels and wind turbine cost may be greatly improved using variable speed systems.

Water pollution control planning for the Taizi River watershed

Water pollution control planning for the Taizi River watershed,a typical Chinese case study,is presented in this paper. Based on comprehensive analysis.water quality in the watershed was assessed and predicated;water quality models for the river and reservoir were built;and function of water bodies and environmental assimilative capacity were determined ;and then the planning for industrial pollution sources and concentrated sewage treatment were made respectively.

The Influence of Construction Manager Experience in Project Accomplishment

Nowadays, construction projects became more complex, where the responsibility of construction manager is to control and plan the project resources in a professional way to handover the project in terms of time, cost, and quality. The aim of this study is to analyze the affect of the long experience of the construction manager on project success; it aims to identify the capability skills that the construction manager should have to complete the project on time. The fmding of this study is to help in understanding the factors that influence the project success through the long experience of the construction manager.

Management System Activities of the Operation and Utilization of GHARR-1

The Ghana Research Reactor-1 (GHARR-1) is a 34 kW low enriched uranium (LEU) Miniature Neutron Source Reactor (MNSR), tank-in-pool type and cooled by natural circulation under atmospheric pressure operating conditions. GHARR-1 is owned by Ghana Atomic Energy Commission (GAEC) and operated by National Nuclear Research Institute (NNRI), one of the institutes of GAEC. GHARR-1 is housed by Nuclear Reactors Research Centre (NRRC), one of the Centres of NNRI. Management/Administration, Radiation protection, Reactor operation and maintenance, Reactor utilization and Physical protection are the various systems/units that integrate to manage the activities of operation and utilization of GHARR-1 in addition to the quality assurance and quality control management system of the research reactor facility. The GHARR-1 which is currently in operation follows a robust maintenance culture adopted by the management system and this has made it possible to keep the reactor in operation with minimal interruption. The management system activities adopted at the Centre to ensure safety of the workers, public and the research reactor facility include authorization of the operation of the reactor for any experiments/modifications;providing material and financial resources for maintaining the research reactor facility;following standard procedures while carrying out Neutron Activation Analysis;participation in IAEA proficiency test;irradiation sites/positions characterization;following standard procedures while carrying out reactor operation and maintenance including reactor and pool water purification and other related activities;monitoring radiation levels in the controlled, supervised and uncontrolled areas of the research reactor facility as well as during reactor operation and maintenance;controlling the physical entry of the workers and public into the research reactor facility;and ensuring that the security structures provided to protect the reactor facility are functioning properly. The thorough knowledge on the functions of the various components that make up the electrical/electronic and control systems of the reactor has been observed to be important for continuous successful maintenance of the research reactor to keep the reactor in operation. This work provides some management system activities adopted to monitor the activities of the research reactor operation and utilization to guarantee safety of workers, public and the environment as well as to safeguard a continuous operation of the research reactor. These management system activities adopted among others, are in the form of Monitoring Forms provided for monitoring the activities of the research reactor operation and utilization in order to ensure standard procedures and specifications are followed and quality services are rendered to the public.

机器学习视角下风味分子研究及其在茉莉花茶中的应用

旨在探讨机器学习在风味分子研究领域的应用,尤其是其在茉莉花茶风味分析中的实践。风味分子的研究是理解和优化食品、特别是茶类饮品味道和品质的基础。机器学习技术的引入为风味分子的识别和分析打开了新的视野。概述了风味分子的基本概念和研究方法,详细讨论了机器学习在解析分子结构与风味特性关系、茉莉花茶品质预测与控制、风味分析、预测与优化、智能化加工等方面的应用,并提出了研究展望,以期为提升茉莉花茶的品质和茶产业发展提供技术支持。

油田开发中精细油藏描述成果平台建设研究

精细油藏描述是油田开发最基础的工作之一,历来受到研究者的高度重视。目前精细油藏描述中存在的突出问题主要包括研究成果继承性差、基础资料存储不规范、专业软件需求缺口大、成果应用需加强和成果存储管理不规范等5方面。文章通过精细油藏描述成果平台建设,可以从基础数据的整理准备、专业软件共享和协同研究、成果标准规范化存储管理等方面解决上述问题。精细油藏描述数据管理主要包括项目整体数据信息的统计和分析、项目研究数据的整理和统计、成果平台与其他数据平台的对接和数据调用等。精细油藏描述协同研究过程主要包括专业软件的平台实现和使用、不同专业软件之间中间成果的转换和调用、研究工作的自动化实现和完成。精细油藏描述成果存储和管理主要包括成果上传管理中格式的统一规范、成果存储上传中的质量控制、成果生产应用中的跟踪和更新。

研究型医院临床研究全流程质量控制的构建与运行

研究型医院开展的临床研究项目越来越多。通过对研究型医院开展的临床研究进行包括立项前、实施中、结题后等多角度、全流程的质量控制,可以及时识别临床研究中存在的风险或潜在风险因素,实时评估并解决质量问题,避免发生重大临床研究问题的可能性。研究型医院通过全流程质控过程中及时主动发现问题,确立协调机制、优化沟通流程,减少研究项目质量问题的发生,持续完善临床研究的质量管理体系,保证研究合规、数据完整准确,提升研究结论的可靠性。

船舶建造物料控制标准研究

船舶建造过程中涉及到的物料种类繁多,各具特色,它们各自在船舶建造中发挥着不可替代的作用。本文从船舶建造物料采购流程与策略、库存管理与优化、质量控制与检验等几方面研究船舶建造物料控制标准,以期能够合理地选用和管理这些物料,最终确保船舶建造的质量和效率。

混合式教学随机对照试验研究的医学教育论文质量分析

目的 分析我国医学教育领域混合式教学随机对照试验研究的期刊论文质量,以规范混合式教学随机对照试验研究论文的写作和提高混合式教学随机对照试验研究论文的水平。方法 在中国知网、万方数据知识服务平台、维普网、Scopus数据库检索相关论文,共纳入自建库起至2023年12月31日发表的我国医学教育领域混合式教学随机对照试验研究论文73篇。参考CONSORT规范的条目自制论文质量分析量表。量表包含5个主题内容22个条目:文题和摘要主题(含2个条目)、引言主题(含2个条目)、方法主题(含13个条目)、结果主题(含3个条目)、讨论和其他主题(含2个条目)。若论文中具有符合或描述此条目的内容,计1分,否则计0分,各条目的评分相加得出论文的总分。同时,比较核心期刊论文与非核心期刊论文、双一流高校论文与非双一流高校论文之间的评分差异。结果 本研究最终纳入73篇中文论文进行分析。73篇论文整体评分为(12.02±3.79)分,最低评分为5分,最高评分为17分。在22个条目中,有10个条目的论文符合率低于50.0%。其中,以下5个条目中的论文符合率最低:“文题能够识别是随机对照试验”和“随机化后脱落的例数和原因”的论文符合率均为0%;“研究所需要的样本量”的论文符合率为1.4%(1/73);“受试者合格的纳入标准”的论文符合率为13.7%(10/73);“随机序列产生的方法”的论文符合率为21.9%(16/73)。核心期刊论文与非核心期刊论文(t=0.304,P=0.605)、双一流高校论文与非双一流高校论文(t=1.674,P=0.532)之间的评分差异均无统计学意义。结论 我国医学教育领域混合式教学随机对照试验研究的论文整体质量不高。其中,研究者对“文题能够识别是随机对照试验”、“随机化后脱落的例数和原因”、“研究所需要的样本量”、“受试者合格的纳入标准”和“随机序列产生的方法”等条目描述得较少,需要研究者在研究设计、研究实施和论文写作阶段都予以重视并加以改进。

超额商誉与商业信用成本:基于风险和内控视角

为厘清超额商誉与商业信用成本间的关系,从供应商与企业间融资成本视角出发,以2014—2021年沪深A股公司为样本,基于信号传递理论,分析超额商誉对商业信用成本的影响机制。研究发现:超额商誉正向影响企业商业信用成本;超额商誉通过加剧企业经营风险,进而增加商业信用成本;较高的内部控制质量对超额商誉与商业信用成本间关系起负向调节作用,且随着内部控制质量的提升,超额商誉加剧经营风险的作用会有所减少,相应其对商业信用成本的正向影响也会减弱;在独立董事比例高、高管股权激励水平高和高管薪酬激励水平低的情形下,超额商誉对商业信用成本的正向影响降低,较高的独董比例和高管股权激励能一定程度缓解超额商誉的负面影响。

蒙药材质量标准及质量控制方法的研究进展

蒙药材质量稳定是保证蒙医药长久发展的首要前提。建立科学、完善的药材质量标准不仅可以保证临床用药的安全、有效,可为后续蒙药制剂的生产提供稳定的质量保证。本文对历版蒙药材及饮片质量标准的主要内容进行对比总结,阐述蒙药材标准的变化历程;总结蒙药材质量标准及现代分析技术中常见的质量控制方法;并对质量标准中存在的问题进行分析讨论,为推动蒙药标准化、现代化发展提供参考。