Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-...Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-related quality of life(HRQoL)for people living with HIV(PLWHIV)required solutions beyond antiretroviral therapy and viral load suppression.This study will explore the role of personality,social economic and prevention strategy effection on HRQoL among people living with HIV/AIDS.Methods::A cross-sectional study was conducted among PLWHIV aged more than 16 years old in the 10 municipalities in Yunnan Province,China from October 2019 to May 2020,enrolling total 1997 participants.Individual-level HRQoL data were measured by 12-item Short Form Health Survey(SF-12)and EuroQol Five Dimensions Questionnaire(EQ-5D-5L).We assembled municipal-level data about social economic from Yunnan Statistical Yearbook in 2020 and strategy practice information from the self-evaluation system.We used the principal component analysis to build the social economic and strategy effect on each area respectively and one-way ANOVA was used to perform univariate analysis to identify the predictors with significant differences.Finally we used multi-level model(MLM)to explore the personality,social economic and strategy effects in health-related quality of life among PLWHIV.Results::The global score for quality of life measured using EQ-5D-5L had an estimated mean score(standard deviation,SD)of 0.901±0.146.The HRQoL score measured using PCS-12 had an estimated mean score(SD)of 46.62±8.55.The mean MCS-12 score(SD)was estimated to be 47.80±9.71.The area-level predictors explained a proportion of 13.6-17.2%for the between-area variation of the HRQoL scores,regardless of the total HRQoL,physical component and mental component.The impacts of stigma(P<0.01),social support(P<0.001),anxiety(P<0.001),depression(P<0.05)and social economic status(P<0.05)on HRQoL at the individual-level were significantly different.The plots visualized the impact of individual-level factors on a respondent’s HRQoL was modified by the area-level characteristics.Conclusions::The study identified the possible strategy determinant of individual HRQoL of PLWHIV and also the area effect on HRQoL.Stigma,social support,anxiety,depression and social economic status were the individual-level determinants on HRQoL.These could be a valuable resource for evaluating the overall health of the areas and help improve local decision making.展开更多
目的了解沙盘游戏疗法对少年肾病综合征患儿心理特征、社交焦虑及生活质量的影响。方法采用便利抽样方法抽取武汉市某三级甲等医院2018年5月-2021年5月收治的700例少年肾病综合征患儿为研究对象,将其随机分为观察组和对照组,每组350例,...目的了解沙盘游戏疗法对少年肾病综合征患儿心理特征、社交焦虑及生活质量的影响。方法采用便利抽样方法抽取武汉市某三级甲等医院2018年5月-2021年5月收治的700例少年肾病综合征患儿为研究对象,将其随机分为观察组和对照组,每组350例,其中对照组给予常规干预(即入院时介绍院内相关情况及疾病注意事项),观察组在对照组基础上实施沙盘游戏疗法。观察两组患儿干预前后应用Conners父母症状问卷(Parent Symptom Questionnaire,PSQ)、儿少心理健康量表(Mental Health Scale for Child and Adolescent,MHS-CA)、儿童社交焦虑量表(Social Anxiety Scale for Children,SASC)、儿少主观生活质量问卷(Inventory of Subjective Life Quality,ISLQ)评分。结果观察组干预后PSQ评分中各维度评分均明显低于对照组(P<0.05,Cohen's d>0.8),观察组干预后MHS-CA评分中各维度评分均明显高于对照组(P<0.05,Cohen's d>0.8),观察组干预后SASC评分中各维度评分均明显低于对照组(P<0.05,Cohen's d>0.8),观察组干预后ISLQ评分中各维度评分均明显高于对照组(P<0.05,Cohen's d>0.8)。结论沙盘游戏疗法能明显改善少年肾病综合征患儿的心理健康程度,缓解其社交焦虑,提升日常生活质量。展开更多
基金Our study was supported by National Nature Science Foundation of China(No.71904166)Yunnan high-level medical cultivation programme(No.H-2018103)13th Five-year National S&T Major Project for Comprehensive Pilots(No.2018ZX10715006).
文摘Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-related quality of life(HRQoL)for people living with HIV(PLWHIV)required solutions beyond antiretroviral therapy and viral load suppression.This study will explore the role of personality,social economic and prevention strategy effection on HRQoL among people living with HIV/AIDS.Methods::A cross-sectional study was conducted among PLWHIV aged more than 16 years old in the 10 municipalities in Yunnan Province,China from October 2019 to May 2020,enrolling total 1997 participants.Individual-level HRQoL data were measured by 12-item Short Form Health Survey(SF-12)and EuroQol Five Dimensions Questionnaire(EQ-5D-5L).We assembled municipal-level data about social economic from Yunnan Statistical Yearbook in 2020 and strategy practice information from the self-evaluation system.We used the principal component analysis to build the social economic and strategy effect on each area respectively and one-way ANOVA was used to perform univariate analysis to identify the predictors with significant differences.Finally we used multi-level model(MLM)to explore the personality,social economic and strategy effects in health-related quality of life among PLWHIV.Results::The global score for quality of life measured using EQ-5D-5L had an estimated mean score(standard deviation,SD)of 0.901±0.146.The HRQoL score measured using PCS-12 had an estimated mean score(SD)of 46.62±8.55.The mean MCS-12 score(SD)was estimated to be 47.80±9.71.The area-level predictors explained a proportion of 13.6-17.2%for the between-area variation of the HRQoL scores,regardless of the total HRQoL,physical component and mental component.The impacts of stigma(P<0.01),social support(P<0.001),anxiety(P<0.001),depression(P<0.05)and social economic status(P<0.05)on HRQoL at the individual-level were significantly different.The plots visualized the impact of individual-level factors on a respondent’s HRQoL was modified by the area-level characteristics.Conclusions::The study identified the possible strategy determinant of individual HRQoL of PLWHIV and also the area effect on HRQoL.Stigma,social support,anxiety,depression and social economic status were the individual-level determinants on HRQoL.These could be a valuable resource for evaluating the overall health of the areas and help improve local decision making.
文摘目的了解沙盘游戏疗法对少年肾病综合征患儿心理特征、社交焦虑及生活质量的影响。方法采用便利抽样方法抽取武汉市某三级甲等医院2018年5月-2021年5月收治的700例少年肾病综合征患儿为研究对象,将其随机分为观察组和对照组,每组350例,其中对照组给予常规干预(即入院时介绍院内相关情况及疾病注意事项),观察组在对照组基础上实施沙盘游戏疗法。观察两组患儿干预前后应用Conners父母症状问卷(Parent Symptom Questionnaire,PSQ)、儿少心理健康量表(Mental Health Scale for Child and Adolescent,MHS-CA)、儿童社交焦虑量表(Social Anxiety Scale for Children,SASC)、儿少主观生活质量问卷(Inventory of Subjective Life Quality,ISLQ)评分。结果观察组干预后PSQ评分中各维度评分均明显低于对照组(P<0.05,Cohen's d>0.8),观察组干预后MHS-CA评分中各维度评分均明显高于对照组(P<0.05,Cohen's d>0.8),观察组干预后SASC评分中各维度评分均明显低于对照组(P<0.05,Cohen's d>0.8),观察组干预后ISLQ评分中各维度评分均明显高于对照组(P<0.05,Cohen's d>0.8)。结论沙盘游戏疗法能明显改善少年肾病综合征患儿的心理健康程度,缓解其社交焦虑,提升日常生活质量。
