A problem in chemical analysis in connection with measurements of a substance normally occurring in a sample, or identification of a substance which should not exist in a sample, is insufficient selectivity. In this a...A problem in chemical analysis in connection with measurements of a substance normally occurring in a sample, or identification of a substance which should not exist in a sample, is insufficient selectivity. In this article, we analyze this problem and propose remedies. We use a real doping case to illustrate how chemical noise causes a serious selectivity problem, probably causing a false positive outcome.展开更多
The differences in intracellular and extracellular protein expressions between human prostate cancer lines LNCap and DU145 were examined, The proteins of the two cell lines were extracted and condensed by using protei...The differences in intracellular and extracellular protein expressions between human prostate cancer lines LNCap and DU145 were examined, The proteins of the two cell lines were extracted and condensed by using protein extraction kits. And the intracellular and extracellular proteins were quantitatively detected on a micro-plate reader by using bicinchoninic acid (BCA) method. The proteins in cell culture fluid were qualitatively assayed by SELDI-TOF-MS, The results showed that the intracellular protein contents of LNCap cells were extremely higher than those of DU145 cells. After serum-free culture, both intracellular and extracellular protein contents of LNCap and DU145 were decreased to some extent. And the intracellular proteins were decreased by 5% in LNCap and by 36% in DU145 respectively, while the extracellular proteins were decreased by 89% in LNCap and 96% in DU145 respectively. SELDI assay revealed that there were 5 marker proteins in LNCap and 6 in DU145. Although both LNCap and DU145 cell lines originated from human prostate cancer, they had some differences in protein expression.展开更多
A microgrid is a combination of distributed energy resources and controllable loads. The main objective of this research is to optimize energy flow within a microgrid with regards to reliability in grid connected mode...A microgrid is a combination of distributed energy resources and controllable loads. The main objective of this research is to optimize energy flow within a microgrid with regards to reliability in grid connected mode. A microgrid with combined heat and power, natural gas generator, diesel generator, solar energy, wind energy, and battery energy storage along with a critical load is considered in this research. An event oriented analytical method called FTA (fault trees analysis) is implemented for reliability optimization using PTC Windchill Solutions software in a microgrid. The reliability of each component in each energy source of the microgrid is calculated using FTA. The reliability of the critical load is evaluated. The quantitative and qualitative results of FTA are evaluated in order to interpret the results of fault tree. The sensitivity and uncertainty of the fault tree results for critical load is deduced by calculating the importance measures such as risk achievement worth, risk reduction worth, criticality importance and Fussel-Vesely importance. Finally from the results the components that are sensitive and at high risk are deduced.展开更多
Social progress is constantly influenced by corruption and clientelism. One of the major causes is slow activityfrom experts on theoretical and practical management. In their decisions, they are not sufficiently ready...Social progress is constantly influenced by corruption and clientelism. One of the major causes is slow activityfrom experts on theoretical and practical management. In their decisions, they are not sufficiently ready to react todynamism of innovations in technical disciplines and current theory and practice in management. Contemporaryphilosophy of management is based on maximising quantity, expecting to deal with quality in due course.Management is focused on quantitative values and disregards the significance of the unity between quantity andquality. This leads to lack of transparency within management and uncertain efficiency of the decision-makingprocess. Disintegration affects the cooperation between individual production and administration branches. Theacademic world sees ethics more as a theoretical discipline connected with social sciences. Many companies,however, have begun to realise the need for innovation as part of successful long-term enterprising and creatingethical relationships inside and outside the company. Corruption scandals and increasing economic crime show thatit is counterproductive to advance business environment without adhering to moral and ethical principles.展开更多
The aim of this paper is to show how qualitative and quantitative approaches can be complementary to study internet financial communication in a thesis by papers and how grounded theory (GT) can be the link among th...The aim of this paper is to show how qualitative and quantitative approaches can be complementary to study internet financial communication in a thesis by papers and how grounded theory (GT) can be the link among the different papers of the thesis. The study context of our thesis was the unregulated markets of New York Stock Exchange (NYSE) Euronext Brussels and the problematic rose from this context: What is the voluntary effort of communication when there is no obligation of internet financial communication? Four papers tried to answer this central question and other following research questions. To answer those research questions, several methodological approaches were used: content analysis of websites and scoring, linear regression, paired sample, and interviews. At the end of our thesis by papers, we discovered that GT was the general methodological travel among the papers: Every article had for vocation to try to answer the questions raised by the previous article.展开更多
文摘A problem in chemical analysis in connection with measurements of a substance normally occurring in a sample, or identification of a substance which should not exist in a sample, is insufficient selectivity. In this article, we analyze this problem and propose remedies. We use a real doping case to illustrate how chemical noise causes a serious selectivity problem, probably causing a false positive outcome.
文摘The differences in intracellular and extracellular protein expressions between human prostate cancer lines LNCap and DU145 were examined, The proteins of the two cell lines were extracted and condensed by using protein extraction kits. And the intracellular and extracellular proteins were quantitatively detected on a micro-plate reader by using bicinchoninic acid (BCA) method. The proteins in cell culture fluid were qualitatively assayed by SELDI-TOF-MS, The results showed that the intracellular protein contents of LNCap cells were extremely higher than those of DU145 cells. After serum-free culture, both intracellular and extracellular protein contents of LNCap and DU145 were decreased to some extent. And the intracellular proteins were decreased by 5% in LNCap and by 36% in DU145 respectively, while the extracellular proteins were decreased by 89% in LNCap and 96% in DU145 respectively. SELDI assay revealed that there were 5 marker proteins in LNCap and 6 in DU145. Although both LNCap and DU145 cell lines originated from human prostate cancer, they had some differences in protein expression.
文摘A microgrid is a combination of distributed energy resources and controllable loads. The main objective of this research is to optimize energy flow within a microgrid with regards to reliability in grid connected mode. A microgrid with combined heat and power, natural gas generator, diesel generator, solar energy, wind energy, and battery energy storage along with a critical load is considered in this research. An event oriented analytical method called FTA (fault trees analysis) is implemented for reliability optimization using PTC Windchill Solutions software in a microgrid. The reliability of each component in each energy source of the microgrid is calculated using FTA. The reliability of the critical load is evaluated. The quantitative and qualitative results of FTA are evaluated in order to interpret the results of fault tree. The sensitivity and uncertainty of the fault tree results for critical load is deduced by calculating the importance measures such as risk achievement worth, risk reduction worth, criticality importance and Fussel-Vesely importance. Finally from the results the components that are sensitive and at high risk are deduced.
文摘Social progress is constantly influenced by corruption and clientelism. One of the major causes is slow activityfrom experts on theoretical and practical management. In their decisions, they are not sufficiently ready to react todynamism of innovations in technical disciplines and current theory and practice in management. Contemporaryphilosophy of management is based on maximising quantity, expecting to deal with quality in due course.Management is focused on quantitative values and disregards the significance of the unity between quantity andquality. This leads to lack of transparency within management and uncertain efficiency of the decision-makingprocess. Disintegration affects the cooperation between individual production and administration branches. Theacademic world sees ethics more as a theoretical discipline connected with social sciences. Many companies,however, have begun to realise the need for innovation as part of successful long-term enterprising and creatingethical relationships inside and outside the company. Corruption scandals and increasing economic crime show thatit is counterproductive to advance business environment without adhering to moral and ethical principles.
文摘The aim of this paper is to show how qualitative and quantitative approaches can be complementary to study internet financial communication in a thesis by papers and how grounded theory (GT) can be the link among the different papers of the thesis. The study context of our thesis was the unregulated markets of New York Stock Exchange (NYSE) Euronext Brussels and the problematic rose from this context: What is the voluntary effort of communication when there is no obligation of internet financial communication? Four papers tried to answer this central question and other following research questions. To answer those research questions, several methodological approaches were used: content analysis of websites and scoring, linear regression, paired sample, and interviews. At the end of our thesis by papers, we discovered that GT was the general methodological travel among the papers: Every article had for vocation to try to answer the questions raised by the previous article.