The variation of air temperature measurement errors using two different radiation shields (DTR502B Vaisala,Finland,and HYTFZ01,Huayun Tongda Satcom,China) was studied.Datasets were collected in the field at the Daxi...The variation of air temperature measurement errors using two different radiation shields (DTR502B Vaisala,Finland,and HYTFZ01,Huayun Tongda Satcom,China) was studied.Datasets were collected in the field at the Daxing weather station in Beijing from June 2011 to May 2012.Most air temperature values obtained with these two commonly used radiation shields were lower than the reference records obtained with the new Fiber Reinforced Polymers (FRP) Stevenson screen.In most cases,the air temperature errors when using the two devices were smaller on overcast and rainy days than on sunny days; and smaller when using the imported rather than the Chinese shield.The measured errors changed sharply at sunrise and sunset,and reached maxima at noon.Their diurnal variation characteristics were,naturally,related to changes in solar radiation.The relationships between the record errors,global radiation,and wind speed were nonlinear.An improved correction method was proposed based on the approach described by Nakamura and Mahrt (2005) (NM05),in which the impact of the solar zenith angle (SZA) on the temperature error is considered and extreme errors due to changes in SZA can be corrected effectively.Measurement errors were reduced significantly after correction by either method for both shields.The error reduction rate using the improved correction method for the Chinese and imported shields were 3.3% and 40.4% higher than those using the NM05 method,respectively.展开更多
By deriving the stress concentration factor of theestimation approach for residual fatigue life’ an estimationapproach for structure crack propagation based on multiplefactors correction is proposed. Then’ the quant...By deriving the stress concentration factor of theestimation approach for residual fatigue life’ an estimationapproach for structure crack propagation based on multiplefactors correction is proposed. Then’ the quantitativeexpression among the structure factor’ stress ratio’ loadingtype’ the manufacture processing factor and the crackpropagation is achieved. The proposed approach iimplemented in a case study for an instance structure’ and theinfluences of correction factors on the crack propagation areanalyzed. Meanwhile’ the probabilistic method based onWeibull distribution probability density function is selected toevaluate the precision of the corrected estimation approach’and the probability density of results is calculated by theprobability density function. It is shown that the resultsestimated by the corrected approach is more precise than thoseestimated by the fracture mechanics, and they are closer to thetest data.展开更多
To overcome the drawbacks such as irregular circuit construction and low system throughput that exist in conventional methods, a new factor correction scheme for coordinate rotation digital computer( CORDIC) algorit...To overcome the drawbacks such as irregular circuit construction and low system throughput that exist in conventional methods, a new factor correction scheme for coordinate rotation digital computer( CORDIC) algorithm is proposed. Based on the relationship between the iteration formulae, a new iteration formula is introduced, which leads the correction operation to be several simple shifting and adding operations. As one key part, the effects caused by rounding error are analyzed mathematically and it is concluded that the effects can be degraded by an appropriate selection of coefficients in the iteration formula. The model is then set up in Matlab and coded in Verilog HDL language. The proposed algorithm is also synthesized and verified in field-programmable gate array (FPGA). The results show that this new scheme requires only one additional clock cycle and there is no change in the elementary iteration for the same precision compared with the conventional algorithm. In addition, the circuit realization is regular and the change in system throughput is very minimal.展开更多
Ionising radiation therapy is a common treatment modality for different types of cancer and its use is expected to increase with advances in screening and early detection of cancer.Radiation injury to the gastrointest...Ionising radiation therapy is a common treatment modality for different types of cancer and its use is expected to increase with advances in screening and early detection of cancer.Radiation injury to the gastrointestinal tract is important factor working against better utility of this important therapeutic modality.Cancer survivors can suffer a wide variety of acute and chronic symptoms following radiotherapy,which significantly reduces their quality of life as well as adding an extra burden to the cost of health care.The accurate diagnosis and treatment of intestinal radiation injury often represents a clinical challenge to practicing physicians in both gastroenterology and oncology.Despite the growing recognition of the problem and some advances in understanding the cellular and molecular mechanisms of radiation injury,relatively little is known about the pathophysiology of gastrointestinal radiation injury or any possible susceptibility factors that could aggravate its severity.The aims of this review are to examine the various clinical manifestations of post-radiation gastrointestinal symptoms,to discuss possible patient and treatment factors implicated in normal gastrointestinal tissue radiosensitivity and to outline different mechanisms of intestinal tissue injury.展开更多
In order to analyze the effect of wavelength-dependent radiation-induced attenuation (RIA) on the mean trans- mission wavelength in optical fiber and the scale factor of interferometric fiber optic gyroscopes (IFOG...In order to analyze the effect of wavelength-dependent radiation-induced attenuation (RIA) on the mean trans- mission wavelength in optical fiber and the scale factor of interferometric fiber optic gyroscopes (IFOGs), three types of polarization-maintaining (PM) fibers are tested by using a 60Co γ-radiation source. The observed different mean wave- length shift (MWS) behaviors for different fibers are interpreted by color-center theory involving dose rate-dependent absorption bands in ultraviolet and visible ranges and total dose-dependent near-infrared absorption bands. To evaluate the mean wavelength variation in a fiber coil and the induced scale factor change for space-borne IFOGs under low radiation doses in a space environment, the influence of dose rate on the mean wavelength is investigated by testing four germanium (Ge) doped fibers and two germanium-phosphorus (Ge-P) codoped fibers irradiated at different dose rates. Experimental results indicate that the Ge-doped fibers show the least mean wavelength shift during irradiation and their mean wavelength of optical signal transmission in fibers will shift to a shorter wavelength in a low-dose-rate radiation environment. Finally, the change in the scale factor of IFOG resulting from the mean wavelength shift is estimated and tested, and it is found that the significant radiation-induced scale factor variation must be considered during the design of space-borne IFOGs.展开更多
AIM: To transfer human HGF gene into the liver of rats by direct electroporation as a means to prevent radiationinduced liver damage.METHODS: Rat whole liver irradiation model was accomplished by intra-operative appro...AIM: To transfer human HGF gene into the liver of rats by direct electroporation as a means to prevent radiationinduced liver damage.METHODS: Rat whole liver irradiation model was accomplished by intra-operative approach. HGF plasmid was injected into liver and transferred by electroporation using a pulse generator. Control rats (n = 8) received electrogene therapy (EGT) vehicle plasmid and another 8rats received HGF-EGT 100 μg 48 h before WLIR.Expression of HGF in liver was examined by RT-PCR and ELISA methods. Apoptosis was determined by TUNEL assay. Histopathology was evaluated 10 wk after whole liver irradiation.RESULTS: Marked decrease of apoptotic cells and downregulation of transforming growth factor-beta 1 (TGF-β1)mRNA were observed in the HGF-EGT group 2 d after liver irradiation compared to control animals. Less evidence of radiation-induced liver damage was observed morphologically in liver specimen 10 wk after liver irradiation and longer median survival time was observed from HGF-EGT group (14 wk) compared to control rats (5 wk). (P = 0.031).CONCLUSION: For the first time it has been demonstrated that HGF-EGT would prevent liver from radiation-induced liver damage by preventing apoptosis and down-regulation of TGF-β1.展开更多
When there are installations of air velocity sensors in the mining industry for real-time airflow monitoring, a problem exists with how the monitored air velocity at a fixed location corresponds to the average air vel...When there are installations of air velocity sensors in the mining industry for real-time airflow monitoring, a problem exists with how the monitored air velocity at a fixed location corresponds to the average air velocity, which is used to determine the volume flow rate of air in an entry with the cross-sectional area. Correction factors have been practically employed to convert a measured centerline air velocity to the average air velocity. However, studies on the recommended correction factors of the sensor-measured air velocity to the average air velocity at cross sections are still lacking. A comprehensive airflow measurement was made at the Safety Research Coal Mine, Bruceton, PA, using three measuring methods including single-point reading, moving traverse, and fixed-point traverse. The air velocity distribution at each measuring station was analyzed using an air velocity contour map generated with Surfer~. The correction factors at each measuring station for both the centerline and the sensor location were calculated and are discussed.展开更多
In this paper, period-doubling bifurcation in a two-stage power factor correction converter is analyzed by using the method of incremental harmonic balance (IHB) and Floquet theory. A two-stage power factor correcti...In this paper, period-doubling bifurcation in a two-stage power factor correction converter is analyzed by using the method of incremental harmonic balance (IHB) and Floquet theory. A two-stage power factor correction converter typically employs a cascade configuration of a pre-regulator boost power factor correction converter with average current mode control to achieve a near unity power factor and a tightly regulated post-regulator DC-DC Buck converter with voltage feedback control to regulate the output voltage. Based on the assumption that the tightly regulated postregulator DC-DC Buck converter is represented as a constant power sink and some other assumptions, the simplified model of the two-stage power factor correction converter is derived and its approximate periodic solution is calculated by the method of IHB. And then, the stability of the system is investigated by using Floquet theory and the stable boundaries are presented on the selected parameter spaces. Finally, some experimental results are given to confirm the effectiveness of the theoretical analysis.展开更多
Radiative transfer modal simulations were used to investigate the erythemal ultraviolet (EUV) correction factors by separating the UV-A and UV-B spectral ranges. The correction factor was defined as the ratio of EUV...Radiative transfer modal simulations were used to investigate the erythemal ultraviolet (EUV) correction factors by separating the UV-A and UV-B spectral ranges. The correction factor was defined as the ratio of EUV caused by changing the amounts and characteristics of the extinction and scattering materials. The EUV correction factors (CFEUV) for UV-A [CFEUV(A)] and UV-B [CFEUV(B)] were affected by changes in the total ozone, optical depths of aerosol and cloud, and the solar zenith angle. The differences between CFEUV(A) and CFEUV(B) were also estimated as a function of solar zenith angle, the optical depths of aerosol and cloud, and total ozone. The differences between CFEUV(A) and CFEUV(B) ranged from -5.0% to 25.0% for aerosols, and from -9.5% to 2.0% for clouds in all simulations for different solar zenith angles and optical depths of aerosol and cloud. The rate of decline of CFEUV per unit optical depth between UV-A and UV-B differed by up to 20% for the same aerosol and cloud conditions. For total ozone, the variation in CFEUV(A) was negligible compared with that in CFEUV(B) because of the effective spectral range of the ozone absorption band. In addition, the sensitivity of the CFEUVs due to changes in surface conditions (i.e., surface albedo and surface altitude) was also estimated by using the model in this study. For changes in surface albedo, the sensitivity of the CFEUVs was 2.9%-4.1% per 0.1 albedo change, depending on the amount of aerosols or clouds. For changes in surface altitude, the sensitivity of CFEUV(B) was twice that of CFEUV(A), because the Rayleigh optical depth increased significantly at shorter wavelengths.展开更多
Relaxation time spectra (RTS) derived from time domain induced polarization data (TDIP) are helpful to assess oil reservoir pore structures. However, due to the sensitivity to the signal-to-noise ratio (SNR), th...Relaxation time spectra (RTS) derived from time domain induced polarization data (TDIP) are helpful to assess oil reservoir pore structures. However, due to the sensitivity to the signal-to-noise ratio (SNR), the inversion accuracy of the traditional singular value decomposition (SVD) inversion method reduces with a decrease of SNR. In order to enhance the inversion accuracy and improve robustness of the inversion method to the SNR, an improved inversion method, based on damping factor and spectrum component residual correction, is proposed in this study. The numerical inversion results show that the oscillation of the RTS derived from the SVD method increased with a decrease of SNR, which makes it impossible to get accurate inversion components. However, the SNR has little influence on inversion components of the improved method, and the RTS has high inversion accuracy and robustness. Moreover, RTS derived from core sample data is basically in accord with the pore-size distribution curve, and the RTS derived from the actual induced polarization logging data is smooth and continuous, which indicates that the improved method is practicable.展开更多
The undrained shear strength (su) of fine-grained soils that can be measured in situ and in laboratory isone of the key geotechnical parameters. The unconfined compression test (UCT) is widely used in laboratoryto...The undrained shear strength (su) of fine-grained soils that can be measured in situ and in laboratory isone of the key geotechnical parameters. The unconfined compression test (UCT) is widely used in laboratoryto measure this parameter due to its simplicity; however, it is severely affected by sampledisturbance. The vane shear test (VST) technique that is less sensitive to sample disturbance involves acorrection factor against the soil plasticity, commonly known as the Bjerrum's correction factor, m. Thisstudy aims to reevaluate the Bjerrum's correction factor in consideration of a different approach and arelatively new method of testing. Atterberg limits test, miniature VST, and reverse extrusion test (RET)were conducted on 120 remolded samples. The effect of soil plasticity on undrained shear strength wasexamined using the liquidity index instead of Bjerrum's correction factor. In comparison with the resultobatined using the Bjerrum's correction factor, the undrained shear strength was better representedwhen su values were correlated with the liquidity index. The results were validated by the RET, whichwas proven to take into account soil plasticity with a reliable degree of accuracy. This study also showsthat the RET has strong promise as a new tool for testing undrained shear strength of fine-grained soils.展开更多
A new method of revising activity values has been derived based on the so called correction factor function for binary alloys with a large difference between two components. The correction factor is a function of phys...A new method of revising activity values has been derived based on the so called correction factor function for binary alloys with a large difference between two components. The correction factor is a function of physical properties formed by the difference of two components. Its absolute value increases with the enhancement of the difference in the character of components. It can be either positive or negative and the rules for selecting the sign of correction factor have been analyzed. Results are in good agreement with the experimental values.展开更多
A new family of converters,high-performance AC/DC power factor correction(PFC) switching converters with one-cycle control technology and active floating-charge technology,was derived and experimentally verified.The t...A new family of converters,high-performance AC/DC power factor correction(PFC) switching converters with one-cycle control technology and active floating-charge technology,was derived and experimentally verified.The topology of a single-phase CCM and DCM Boost-PFC switching converter was also analyzed.Its operating prniciples and control methods were expounded.Based on these,a new type of AC/DC switching converter circuits for PFC combined with one-cycle control technology was presented herein.The proposed AC/DC switching converter significantly helps improve the converter efficiency and its power factor value.展开更多
This paper presents a comprehensive charging operation for an electric-drive-reconfigured onboard charger(EDROC)with active power factor correction(APFC).The charging topology exclusively utilizes the three-phase perm...This paper presents a comprehensive charging operation for an electric-drive-reconfigured onboard charger(EDROC)with active power factor correction(APFC).The charging topology exclusively utilizes the three-phase permanent magnet synchronous motor(PMSM)propulsion system as a three-channel boost-type converter in which only a contactor and a small diode bridge are added.First,the operation scenario of the EDROC is introduced.Second,the relationship between electromagnetic torque and rotor position is investigated.Third,the current ripple cancellation of the EDROC is discussed in detail.Moreover,to implement the single-phase APFC along with charging voltage/current regulation of propulsion battery,control strategies including current balancing and synchronous/interleaving PWM strategies are incorporated.Finally,200W proof-of-concept prototype-based tests are conducted under different operation scenarios.展开更多
This paper presents the global solar radiation (GSR) and cloud transmittance factor (cf) measured at the horizontal surface over a period of one year from 2009 to 2010 using CMP6 Pyranometer and NILUUV Irradiance Mete...This paper presents the global solar radiation (GSR) and cloud transmittance factor (cf) measured at the horizontal surface over a period of one year from 2009 to 2010 using CMP6 Pyranometer and NILUUV Irradiance Meter at Lukla (Latitude 26.69oN,Longitude 86.73?E and Altitude 2850 m) in the foothills of the Mt Everest (8850 m high). Monthly and seasonal variations of global solar radiation as well as correlation between clearness index and cloud transmittance factor at Lukla are presented. The annual average daily global solar radiation is about 3.83 kWh/sq·m/day which is sufficient to promote solar active and passive energy technology at high mountain terrain where there is no other viable alternative sources of energy. The maximum and minimum global solar radiation of 5.33 and 2.08 kWh/sq·m/day is recorded in April and September 2010 respectively. The seasonal variation of solar energy is about 2.87 kWh/sq·m/day and 4.83 kWh/sq·m/day in summer and spring respectively which is not in line with the general trend. The coefficient of determination (R2) between cloud transmittance factor (cf) and clearness factor (K) is found to be 0.97. This novel result can be utilized to estimate the global solar radiation at the horizontal surface where K and cf are available.展开更多
BACKGROUND Radiation pneumonitis(RP)is a severe complication of thoracic radiotherapy that may lead to dyspnea and lung fibrosis,and negatively affects patients’quality of life.AIM To carry out multiple regression an...BACKGROUND Radiation pneumonitis(RP)is a severe complication of thoracic radiotherapy that may lead to dyspnea and lung fibrosis,and negatively affects patients’quality of life.AIM To carry out multiple regression analysis on the influencing factors of radiation pneumonitis.METHODS Records of 234 patients receiving chest radiotherapy in Huzhou Central Hospital(Huzhou,Zhejiang Province,China)from January 2018 to February 2021,and the patients were divided into either a study group or a control group based on the presence of radiation pneumonitis or not.Among them,93 patients with radiation pneumonitis were included in the study group and 141 without radiation pneumonitis were included in the control group.General characteristics,and radiation and imaging examination data of the two groups were collected and compared.Due to the statistical significance observed,multiple regression analysis was performed on age,tumor type,chemotherapy history,forced vital capacity(FVC),forced expiratory volume in the first second(FEV1),carbon monoxide diffusion volume(DLCO),FEV1/FVC ratio,planned target area(PTV),mean lung dose(MLD),total number of radiation fields,percentage of lung tissue in total lung volume(vdose),probability of normal tissue complications(NTCP),and other factors.RESULTS The proportions of patients aged≥60 years and those with the diagnosis of lung cancer and a history of chemotherapy in the study group were higher than those in the control group(P<0.05);FEV1,DLCO,and FEV1/FVC ratio in the study group were lower than those in the control group(P<0.05),while PTV,MLD,total field number,vdose,and NTCP were higher than in the control group(P<0.05).Logistic regression analysis showed that age,lung cancer diagnosis,chemotherapy history,FEV1,FEV1/FVC ratio,PTV,MLD,total number of radiation fields,vdose,and NTCP were risk factors for radiation pneumonitis.CONCLUSION We have identified patient age,type of lung cancer,history of chemotherapy,lung function,and radiotherapy parameters as risk factors for radiation pneumonitis.Comprehensive evaluation and examination should be carried out before radiotherapy to effectively prevent radiation pneumonitis.展开更多
A new type of high power LED drivers is proposed by adopting an improved two-stages non-isolated configuration. In order to improve power factor and achieve accurate average current control under universal input volta...A new type of high power LED drivers is proposed by adopting an improved two-stages non-isolated configuration. In order to improve power factor and achieve accurate average current control under universal input voltages ranging from 100 Vrms to 240 Vrms, the power factor correction and average current mode control methods operating in continuous current conduction mode are designed and implemented. With the LUMILEDS emitter type LEDs, a laboratory prototype is built and measured. And from the measured results, it could be concluded that the proposed driver has many better performances such as high power factor, low current harmonic, accurate average current control and switch protection.展开更多
This paper presents a PFCVF (Power Factor Correction) rectifier that uses a variable frequency source for alternators for electric and hybrid vehicles application. In such application, the frequency of the signal in t...This paper presents a PFCVF (Power Factor Correction) rectifier that uses a variable frequency source for alternators for electric and hybrid vehicles application. In such application, the frequency of the signal in the alternator changes according to the vehicle speed, more over the loading effect on the alternator introduces harmonic currents and increases the alternator apparent power requirements. To overcome these problems and aiming more stability and better design of the alternator, a new third harmonic injection technique is proposed. This technique allows to preserve a good THD (Total Harmonic Distortion) of the input source at any frequency and to decrease losses in semiconductors switches, thereby allowing more stability and reducing the apparent power requirements. A comparative study between the standard and the new technique is made and highlights the effectiveness of the new design. A detailed analysis of the proposed topology is presented and simulations as well as experimental results are shown.展开更多
In this paper, the relationship between radiation crosslinking parameter β and the molecular internal rotating steric factor (σ) for fluoropolymers were studied. An expression calculating the molecular internal rota...In this paper, the relationship between radiation crosslinking parameter β and the molecular internal rotating steric factor (σ) for fluoropolymers were studied. An expression calculating the molecular internal rotating steric factor of fluoropolymers, σ=1.44+(β-0.206)/1.946, was established. σ value obtained by this method is in agreement with that given in the literature.展开更多
In intensity modulated radiation treatment (IMRT) planning, the use of asymmetrically collimated fields that are placed on central axis or its off-set is mostly required. Output is the main topic discussed today for e...In intensity modulated radiation treatment (IMRT) planning, the use of asymmetrically collimated fields that are placed on central axis or its off-set is mostly required. Output is the main topic discussed today for extremely small and/or severe irregularly shaped fields. The air scatter data are involved directly or indirectly in obtaining the output. Despite the fact that extensive data have been published in many studies to provide a guide on the magnitude of output factor for clinical accelerators, there are very few data reviewed about output factor in-air or phantom for off-set fields. This study was aimed to investigate the impact of these conditions for small fields. This study was conducted in Elekta Synergy linear accelerator which produces 6 MV X-ray energy. The in-air output factor (Sc) has been measured by CC04 ion chamber with brass-alloy “build-up” cap and Dose-1 electrometer, and the total output (Scp) measurements were carried on at dose maximum depth in phantom by the same chamber and Thermoluminescence dosimeter (TLD) for 1 - 10 cm2 fields. The all measurements at center of isocenter and off-set fields at three directions (X2, Y1, Diagonal) were done. By decreasing field size from 10 to 2 cm2 at isocenter, the Sc value using CC04 was decreased to 5.4% and Scp using CC04 and TLD to 14.5% and 11% respectively. By increasing off-set value, the Sc and Scp values were increased in all directions comparing to central fields. The maximum increase was obtained in Y1 direction for Sc and Scp. TLD results for Scp is slightly higher than CC04. The dosimetric properties of small fields and their off-set should be evaluated and modelled appropriately in the treatment planning system to ensure accurate dose calculation in Intensity Modulated Radiation Treatment.展开更多
基金financially supported by the Meteorological Key Technology Integration and Application Project funded by the China Meteorological Administration (Grant No.CAMGJ2012M01)the Special Fund of Beijing Meteorological Bureau (Grant No.2011BMBKYZX04)the Nation Natural Science Foundation of China (Grant No.41275114)
文摘The variation of air temperature measurement errors using two different radiation shields (DTR502B Vaisala,Finland,and HYTFZ01,Huayun Tongda Satcom,China) was studied.Datasets were collected in the field at the Daxing weather station in Beijing from June 2011 to May 2012.Most air temperature values obtained with these two commonly used radiation shields were lower than the reference records obtained with the new Fiber Reinforced Polymers (FRP) Stevenson screen.In most cases,the air temperature errors when using the two devices were smaller on overcast and rainy days than on sunny days; and smaller when using the imported rather than the Chinese shield.The measured errors changed sharply at sunrise and sunset,and reached maxima at noon.Their diurnal variation characteristics were,naturally,related to changes in solar radiation.The relationships between the record errors,global radiation,and wind speed were nonlinear.An improved correction method was proposed based on the approach described by Nakamura and Mahrt (2005) (NM05),in which the impact of the solar zenith angle (SZA) on the temperature error is considered and extreme errors due to changes in SZA can be corrected effectively.Measurement errors were reduced significantly after correction by either method for both shields.The error reduction rate using the improved correction method for the Chinese and imported shields were 3.3% and 40.4% higher than those using the NM05 method,respectively.
基金The National Natural Science Foundation of China(No.51675098)Chinese Specialized Research Foundation for Doctoral Program of Higher Education(No.20130092110003)Graduate Student Research Innovation Foundation of Jiangsu Province(No.KYLX15_0059)
文摘By deriving the stress concentration factor of theestimation approach for residual fatigue life’ an estimationapproach for structure crack propagation based on multiplefactors correction is proposed. Then’ the quantitativeexpression among the structure factor’ stress ratio’ loadingtype’ the manufacture processing factor and the crackpropagation is achieved. The proposed approach iimplemented in a case study for an instance structure’ and theinfluences of correction factors on the crack propagation areanalyzed. Meanwhile’ the probabilistic method based onWeibull distribution probability density function is selected toevaluate the precision of the corrected estimation approach’and the probability density of results is calculated by theprobability density function. It is shown that the resultsestimated by the corrected approach is more precise than thoseestimated by the fracture mechanics, and they are closer to thetest data.
基金The National High Technology Research and Development Program of China (863 Program)(No.2007AA01Z280)
文摘To overcome the drawbacks such as irregular circuit construction and low system throughput that exist in conventional methods, a new factor correction scheme for coordinate rotation digital computer( CORDIC) algorithm is proposed. Based on the relationship between the iteration formulae, a new iteration formula is introduced, which leads the correction operation to be several simple shifting and adding operations. As one key part, the effects caused by rounding error are analyzed mathematically and it is concluded that the effects can be degraded by an appropriate selection of coefficients in the iteration formula. The model is then set up in Matlab and coded in Verilog HDL language. The proposed algorithm is also synthesized and verified in field-programmable gate array (FPGA). The results show that this new scheme requires only one additional clock cycle and there is no change in the elementary iteration for the same precision compared with the conventional algorithm. In addition, the circuit realization is regular and the change in system throughput is very minimal.
文摘Ionising radiation therapy is a common treatment modality for different types of cancer and its use is expected to increase with advances in screening and early detection of cancer.Radiation injury to the gastrointestinal tract is important factor working against better utility of this important therapeutic modality.Cancer survivors can suffer a wide variety of acute and chronic symptoms following radiotherapy,which significantly reduces their quality of life as well as adding an extra burden to the cost of health care.The accurate diagnosis and treatment of intestinal radiation injury often represents a clinical challenge to practicing physicians in both gastroenterology and oncology.Despite the growing recognition of the problem and some advances in understanding the cellular and molecular mechanisms of radiation injury,relatively little is known about the pathophysiology of gastrointestinal radiation injury or any possible susceptibility factors that could aggravate its severity.The aims of this review are to examine the various clinical manifestations of post-radiation gastrointestinal symptoms,to discuss possible patient and treatment factors implicated in normal gastrointestinal tissue radiosensitivity and to outline different mechanisms of intestinal tissue injury.
基金Project supported by the National Natural Science Foundation of China (Grant No. 61007040)
文摘In order to analyze the effect of wavelength-dependent radiation-induced attenuation (RIA) on the mean trans- mission wavelength in optical fiber and the scale factor of interferometric fiber optic gyroscopes (IFOGs), three types of polarization-maintaining (PM) fibers are tested by using a 60Co γ-radiation source. The observed different mean wave- length shift (MWS) behaviors for different fibers are interpreted by color-center theory involving dose rate-dependent absorption bands in ultraviolet and visible ranges and total dose-dependent near-infrared absorption bands. To evaluate the mean wavelength variation in a fiber coil and the induced scale factor change for space-borne IFOGs under low radiation doses in a space environment, the influence of dose rate on the mean wavelength is investigated by testing four germanium (Ge) doped fibers and two germanium-phosphorus (Ge-P) codoped fibers irradiated at different dose rates. Experimental results indicate that the Ge-doped fibers show the least mean wavelength shift during irradiation and their mean wavelength of optical signal transmission in fibers will shift to a shorter wavelength in a low-dose-rate radiation environment. Finally, the change in the scale factor of IFOG resulting from the mean wavelength shift is estimated and tested, and it is found that the significant radiation-induced scale factor variation must be considered during the design of space-borne IFOGs.
基金Supported by National Science Council grant NSC-91-275-9075-001 for the development of Boron Neutron Capture Therapy for Hepatoma Treatment
文摘AIM: To transfer human HGF gene into the liver of rats by direct electroporation as a means to prevent radiationinduced liver damage.METHODS: Rat whole liver irradiation model was accomplished by intra-operative approach. HGF plasmid was injected into liver and transferred by electroporation using a pulse generator. Control rats (n = 8) received electrogene therapy (EGT) vehicle plasmid and another 8rats received HGF-EGT 100 μg 48 h before WLIR.Expression of HGF in liver was examined by RT-PCR and ELISA methods. Apoptosis was determined by TUNEL assay. Histopathology was evaluated 10 wk after whole liver irradiation.RESULTS: Marked decrease of apoptotic cells and downregulation of transforming growth factor-beta 1 (TGF-β1)mRNA were observed in the HGF-EGT group 2 d after liver irradiation compared to control animals. Less evidence of radiation-induced liver damage was observed morphologically in liver specimen 10 wk after liver irradiation and longer median survival time was observed from HGF-EGT group (14 wk) compared to control rats (5 wk). (P = 0.031).CONCLUSION: For the first time it has been demonstrated that HGF-EGT would prevent liver from radiation-induced liver damage by preventing apoptosis and down-regulation of TGF-β1.
文摘When there are installations of air velocity sensors in the mining industry for real-time airflow monitoring, a problem exists with how the monitored air velocity at a fixed location corresponds to the average air velocity, which is used to determine the volume flow rate of air in an entry with the cross-sectional area. Correction factors have been practically employed to convert a measured centerline air velocity to the average air velocity. However, studies on the recommended correction factors of the sensor-measured air velocity to the average air velocity at cross sections are still lacking. A comprehensive airflow measurement was made at the Safety Research Coal Mine, Bruceton, PA, using three measuring methods including single-point reading, moving traverse, and fixed-point traverse. The air velocity distribution at each measuring station was analyzed using an air velocity contour map generated with Surfer~. The correction factors at each measuring station for both the centerline and the sensor location were calculated and are discussed.
基金supported by the National Natural Science Foundation of China (Grant No.51007068)the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No.20100201120028)+1 种基金the Fundamental Research Funds for the Central Universities of Chinathe State Key Laboratory of Electrical Insulation and Power Equipment of China (Grant No.EIPE10303)
文摘In this paper, period-doubling bifurcation in a two-stage power factor correction converter is analyzed by using the method of incremental harmonic balance (IHB) and Floquet theory. A two-stage power factor correction converter typically employs a cascade configuration of a pre-regulator boost power factor correction converter with average current mode control to achieve a near unity power factor and a tightly regulated post-regulator DC-DC Buck converter with voltage feedback control to regulate the output voltage. Based on the assumption that the tightly regulated postregulator DC-DC Buck converter is represented as a constant power sink and some other assumptions, the simplified model of the two-stage power factor correction converter is derived and its approximate periodic solution is calculated by the method of IHB. And then, the stability of the system is investigated by using Floquet theory and the stable boundaries are presented on the selected parameter spaces. Finally, some experimental results are given to confirm the effectiveness of the theoretical analysis.
基金funded by the Korea Meteorological Administration Research and Development Program (Grant No. KMIPA 2015-5170)
文摘Radiative transfer modal simulations were used to investigate the erythemal ultraviolet (EUV) correction factors by separating the UV-A and UV-B spectral ranges. The correction factor was defined as the ratio of EUV caused by changing the amounts and characteristics of the extinction and scattering materials. The EUV correction factors (CFEUV) for UV-A [CFEUV(A)] and UV-B [CFEUV(B)] were affected by changes in the total ozone, optical depths of aerosol and cloud, and the solar zenith angle. The differences between CFEUV(A) and CFEUV(B) were also estimated as a function of solar zenith angle, the optical depths of aerosol and cloud, and total ozone. The differences between CFEUV(A) and CFEUV(B) ranged from -5.0% to 25.0% for aerosols, and from -9.5% to 2.0% for clouds in all simulations for different solar zenith angles and optical depths of aerosol and cloud. The rate of decline of CFEUV per unit optical depth between UV-A and UV-B differed by up to 20% for the same aerosol and cloud conditions. For total ozone, the variation in CFEUV(A) was negligible compared with that in CFEUV(B) because of the effective spectral range of the ozone absorption band. In addition, the sensitivity of the CFEUVs due to changes in surface conditions (i.e., surface albedo and surface altitude) was also estimated by using the model in this study. For changes in surface albedo, the sensitivity of the CFEUVs was 2.9%-4.1% per 0.1 albedo change, depending on the amount of aerosols or clouds. For changes in surface altitude, the sensitivity of CFEUV(B) was twice that of CFEUV(A), because the Rayleigh optical depth increased significantly at shorter wavelengths.
基金supported by a project from the Youth Science Foundation of the National Natural Science Foundation of China (11104089)
文摘Relaxation time spectra (RTS) derived from time domain induced polarization data (TDIP) are helpful to assess oil reservoir pore structures. However, due to the sensitivity to the signal-to-noise ratio (SNR), the inversion accuracy of the traditional singular value decomposition (SVD) inversion method reduces with a decrease of SNR. In order to enhance the inversion accuracy and improve robustness of the inversion method to the SNR, an improved inversion method, based on damping factor and spectrum component residual correction, is proposed in this study. The numerical inversion results show that the oscillation of the RTS derived from the SVD method increased with a decrease of SNR, which makes it impossible to get accurate inversion components. However, the SNR has little influence on inversion components of the improved method, and the RTS has high inversion accuracy and robustness. Moreover, RTS derived from core sample data is basically in accord with the pore-size distribution curve, and the RTS derived from the actual induced polarization logging data is smooth and continuous, which indicates that the improved method is practicable.
文摘The undrained shear strength (su) of fine-grained soils that can be measured in situ and in laboratory isone of the key geotechnical parameters. The unconfined compression test (UCT) is widely used in laboratoryto measure this parameter due to its simplicity; however, it is severely affected by sampledisturbance. The vane shear test (VST) technique that is less sensitive to sample disturbance involves acorrection factor against the soil plasticity, commonly known as the Bjerrum's correction factor, m. Thisstudy aims to reevaluate the Bjerrum's correction factor in consideration of a different approach and arelatively new method of testing. Atterberg limits test, miniature VST, and reverse extrusion test (RET)were conducted on 120 remolded samples. The effect of soil plasticity on undrained shear strength wasexamined using the liquidity index instead of Bjerrum's correction factor. In comparison with the resultobatined using the Bjerrum's correction factor, the undrained shear strength was better representedwhen su values were correlated with the liquidity index. The results were validated by the RET, whichwas proven to take into account soil plasticity with a reliable degree of accuracy. This study also showsthat the RET has strong promise as a new tool for testing undrained shear strength of fine-grained soils.
基金Financial support of this research by the National Natural Sci-ence Foundation of China under Grants 50074013 and 59774027and Huo Ying-Dong Education Foundation is gratefully acknowl-edged. Thanks are furthermore due to Chinese-Austrian Scientific Techni
文摘A new method of revising activity values has been derived based on the so called correction factor function for binary alloys with a large difference between two components. The correction factor is a function of physical properties formed by the difference of two components. Its absolute value increases with the enhancement of the difference in the character of components. It can be either positive or negative and the rules for selecting the sign of correction factor have been analyzed. Results are in good agreement with the experimental values.
文摘A new family of converters,high-performance AC/DC power factor correction(PFC) switching converters with one-cycle control technology and active floating-charge technology,was derived and experimentally verified.The topology of a single-phase CCM and DCM Boost-PFC switching converter was also analyzed.Its operating prniciples and control methods were expounded.Based on these,a new type of AC/DC switching converter circuits for PFC combined with one-cycle control technology was presented herein.The proposed AC/DC switching converter significantly helps improve the converter efficiency and its power factor value.
基金This work was supported in part by the National Natural Science Foundation of China(51807098,61673226)and the Six Talent Peaks Project in Jiangsu Province(2015-JY-028).
文摘This paper presents a comprehensive charging operation for an electric-drive-reconfigured onboard charger(EDROC)with active power factor correction(APFC).The charging topology exclusively utilizes the three-phase permanent magnet synchronous motor(PMSM)propulsion system as a three-channel boost-type converter in which only a contactor and a small diode bridge are added.First,the operation scenario of the EDROC is introduced.Second,the relationship between electromagnetic torque and rotor position is investigated.Third,the current ripple cancellation of the EDROC is discussed in detail.Moreover,to implement the single-phase APFC along with charging voltage/current regulation of propulsion battery,control strategies including current balancing and synchronous/interleaving PWM strategies are incorporated.Finally,200W proof-of-concept prototype-based tests are conducted under different operation scenarios.
文摘This paper presents the global solar radiation (GSR) and cloud transmittance factor (cf) measured at the horizontal surface over a period of one year from 2009 to 2010 using CMP6 Pyranometer and NILUUV Irradiance Meter at Lukla (Latitude 26.69oN,Longitude 86.73?E and Altitude 2850 m) in the foothills of the Mt Everest (8850 m high). Monthly and seasonal variations of global solar radiation as well as correlation between clearness index and cloud transmittance factor at Lukla are presented. The annual average daily global solar radiation is about 3.83 kWh/sq·m/day which is sufficient to promote solar active and passive energy technology at high mountain terrain where there is no other viable alternative sources of energy. The maximum and minimum global solar radiation of 5.33 and 2.08 kWh/sq·m/day is recorded in April and September 2010 respectively. The seasonal variation of solar energy is about 2.87 kWh/sq·m/day and 4.83 kWh/sq·m/day in summer and spring respectively which is not in line with the general trend. The coefficient of determination (R2) between cloud transmittance factor (cf) and clearness factor (K) is found to be 0.97. This novel result can be utilized to estimate the global solar radiation at the horizontal surface where K and cf are available.
文摘BACKGROUND Radiation pneumonitis(RP)is a severe complication of thoracic radiotherapy that may lead to dyspnea and lung fibrosis,and negatively affects patients’quality of life.AIM To carry out multiple regression analysis on the influencing factors of radiation pneumonitis.METHODS Records of 234 patients receiving chest radiotherapy in Huzhou Central Hospital(Huzhou,Zhejiang Province,China)from January 2018 to February 2021,and the patients were divided into either a study group or a control group based on the presence of radiation pneumonitis or not.Among them,93 patients with radiation pneumonitis were included in the study group and 141 without radiation pneumonitis were included in the control group.General characteristics,and radiation and imaging examination data of the two groups were collected and compared.Due to the statistical significance observed,multiple regression analysis was performed on age,tumor type,chemotherapy history,forced vital capacity(FVC),forced expiratory volume in the first second(FEV1),carbon monoxide diffusion volume(DLCO),FEV1/FVC ratio,planned target area(PTV),mean lung dose(MLD),total number of radiation fields,percentage of lung tissue in total lung volume(vdose),probability of normal tissue complications(NTCP),and other factors.RESULTS The proportions of patients aged≥60 years and those with the diagnosis of lung cancer and a history of chemotherapy in the study group were higher than those in the control group(P<0.05);FEV1,DLCO,and FEV1/FVC ratio in the study group were lower than those in the control group(P<0.05),while PTV,MLD,total field number,vdose,and NTCP were higher than in the control group(P<0.05).Logistic regression analysis showed that age,lung cancer diagnosis,chemotherapy history,FEV1,FEV1/FVC ratio,PTV,MLD,total number of radiation fields,vdose,and NTCP were risk factors for radiation pneumonitis.CONCLUSION We have identified patient age,type of lung cancer,history of chemotherapy,lung function,and radiotherapy parameters as risk factors for radiation pneumonitis.Comprehensive evaluation and examination should be carried out before radiotherapy to effectively prevent radiation pneumonitis.
文摘A new type of high power LED drivers is proposed by adopting an improved two-stages non-isolated configuration. In order to improve power factor and achieve accurate average current control under universal input voltages ranging from 100 Vrms to 240 Vrms, the power factor correction and average current mode control methods operating in continuous current conduction mode are designed and implemented. With the LUMILEDS emitter type LEDs, a laboratory prototype is built and measured. And from the measured results, it could be concluded that the proposed driver has many better performances such as high power factor, low current harmonic, accurate average current control and switch protection.
文摘This paper presents a PFCVF (Power Factor Correction) rectifier that uses a variable frequency source for alternators for electric and hybrid vehicles application. In such application, the frequency of the signal in the alternator changes according to the vehicle speed, more over the loading effect on the alternator introduces harmonic currents and increases the alternator apparent power requirements. To overcome these problems and aiming more stability and better design of the alternator, a new third harmonic injection technique is proposed. This technique allows to preserve a good THD (Total Harmonic Distortion) of the input source at any frequency and to decrease losses in semiconductors switches, thereby allowing more stability and reducing the apparent power requirements. A comparative study between the standard and the new technique is made and highlights the effectiveness of the new design. A detailed analysis of the proposed topology is presented and simulations as well as experimental results are shown.
基金The project was supported by the research foundation of IAEA, Agency Research Contract No. 4316/RB
文摘In this paper, the relationship between radiation crosslinking parameter β and the molecular internal rotating steric factor (σ) for fluoropolymers were studied. An expression calculating the molecular internal rotating steric factor of fluoropolymers, σ=1.44+(β-0.206)/1.946, was established. σ value obtained by this method is in agreement with that given in the literature.
文摘In intensity modulated radiation treatment (IMRT) planning, the use of asymmetrically collimated fields that are placed on central axis or its off-set is mostly required. Output is the main topic discussed today for extremely small and/or severe irregularly shaped fields. The air scatter data are involved directly or indirectly in obtaining the output. Despite the fact that extensive data have been published in many studies to provide a guide on the magnitude of output factor for clinical accelerators, there are very few data reviewed about output factor in-air or phantom for off-set fields. This study was aimed to investigate the impact of these conditions for small fields. This study was conducted in Elekta Synergy linear accelerator which produces 6 MV X-ray energy. The in-air output factor (Sc) has been measured by CC04 ion chamber with brass-alloy “build-up” cap and Dose-1 electrometer, and the total output (Scp) measurements were carried on at dose maximum depth in phantom by the same chamber and Thermoluminescence dosimeter (TLD) for 1 - 10 cm2 fields. The all measurements at center of isocenter and off-set fields at three directions (X2, Y1, Diagonal) were done. By decreasing field size from 10 to 2 cm2 at isocenter, the Sc value using CC04 was decreased to 5.4% and Scp using CC04 and TLD to 14.5% and 11% respectively. By increasing off-set value, the Sc and Scp values were increased in all directions comparing to central fields. The maximum increase was obtained in Y1 direction for Sc and Scp. TLD results for Scp is slightly higher than CC04. The dosimetric properties of small fields and their off-set should be evaluated and modelled appropriately in the treatment planning system to ensure accurate dose calculation in Intensity Modulated Radiation Treatment.