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Intestinal microecological transplantation for a patient with chronic radiation enteritis:A case report
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作者 Lin Wang Yan Li +1 位作者 Yu-Jing Zhang Li-Hua Peng 《World Journal of Gastroenterology》 SCIE CAS 2024年第19期2603-2611,共9页
BACKGROUND The gut microbiota is strongly associated with radiation-induced gut damage.This study aimed to assess the effectiveness and safety of intestinal microecological transplantation for treating patients with c... BACKGROUND The gut microbiota is strongly associated with radiation-induced gut damage.This study aimed to assess the effectiveness and safety of intestinal microecological transplantation for treating patients with chronic radiation enteritis.CASE SUMMARY A 64-year-old female with cervical cancer developed abdominal pain,diarrhea,and blood in the stool 1 year after radiotherapy.An electronic colonoscopy was performed to diagnose chronic radiation enteritis.Two courses of intestinal microecological transplantation and full-length 16S rRNA microbiological analysis were performed.The patient experienced short-and long-term relief from symptoms without adverse effects.Whole 16S rRNA sequencing revealed significant differences in the intestinal flora’s composition between patient and healthy donors.Pathogenic bacteria,such as Escherichia fergusonii and Romboutsia timonensis,were more in the patient.Beneficial bacteria such as Faecalibacterium prausnitzii,Fusicatenibacter saccharivorans,Ruminococcus bromii,and Bifidobacterium longum were more in the healthy donors.Intestinal microbiota transplantation resulted in a significant change in the patient's intestinal flora composition.The composition converged with the donor's flora,with an increase in core beneficial intestinal bacteria,such as Eubacterium rectale,and a decrease in pathogenic bacteria.Changes in the intestinal flora corresponded with the patients'alleviating clinical symptoms.CONCLUSION Intestinal microecological transplantation is an effective treatment for relieving the clinical symptoms of chronic radiation enteritis by altering the composition of the intestinal flora.This study provides a new approach for treating patients with chronic radiation enteritis. 展开更多
关键词 Chronic radiation enteritis Gut microbial transplantation Intestinal microecology Cancer Quality of life Case report
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Establishment of a prediction model for severe acute radiation enteritis associated with cervical cancer radiotherapy 被引量:7
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作者 Chen-Ying Ma Jing Zhao +6 位作者 Guang-Hui Gan Xiao-Lan He Xiao-Ting Xu Song-Bing Qin Li-Li Wang Li Li Ju-Ying Zhou 《World Journal of Gastroenterology》 SCIE CAS 2023年第8期1344-1358,共15页
BACKGROUND Cervical cancer is one of the most common gynecological malignant tumors.Radiation enteritis(RE)leads to radiotherapy intolerance or termination of radiotherapy,which negatively impacts the therapeutic effe... BACKGROUND Cervical cancer is one of the most common gynecological malignant tumors.Radiation enteritis(RE)leads to radiotherapy intolerance or termination of radiotherapy,which negatively impacts the therapeutic effect and seriously affects the quality of life of patients.If the incidence of RE in patients can be predicted in advance,and targeted clinical preventive treatment can be carried out,the side effects of radiotherapy in cervical cancer patients can be significantly reduced.Furthermore,accurate prediction of RE is essential for the selection of individualized radiation dose and the optimization of the radiotherapy plan.AIM To analyze the relationships between severe acute RE(SARE)of cervical cancer radiotherapy and clinical factors and dose-volume parameters retrospectively.METHODS We included 50 cervical cancer patients who received volumetric modulated arc therapy(VMAT)from September 2017 to June 2018 in the Department of Radiotherapy at The First Affiliated Hospital Soochow University.Clinical and dose-volume histogram factors of patients were collected.Logistic regression analysis was used to evaluate the predictive value of each factor for SARE.A nomogram to predict SARE was developed(SARE scoring system≥3 points)based on the multiple regression coefficients;validity was verified by an internal verification method.RESULTS Gastrointestinal and hematological toxicity of cervical cancer VMAT gradually increased with radiotherapy and reached the peak at the end of radiotherapy.The main adverse reactions were diarrhea,abdominal pain,colitis,anal swelling,and blood in the stool.There was no significant difference in the incidence of gastrointestinal toxicity between the radical and postoperative adjuvant radiotherapy groups(P>0.05).There were significant differences in the small intestine V_(20),V_(30),V_(40),and rectal V40 between adjuvant radiotherapy and radical radiotherapy after surgery(P<0.05).Univariate and multivariate analyses revealed anal bulge rating(OR:14.779,95%CI:1.281-170.547,P=0.031)and disease activity index(DAI)score(OR:53.928,95%CI:3.822-760.948,P=0.003)as independent predictors of SARE.CONCLUSION Anal bulge rating(>0.500 grade)and DAI score(>2.165 points)can predict SARE.The nomogram shows potential value in clinical practice. 展开更多
关键词 Cervical cancer Intensity-modulated radiotherapy radiation enteritis NOMOGRAM PreDICTOR
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Modification of end-loop ileostomy for the treatment of ischemic or radiation enteritis 被引量:1
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作者 Konstantinos Tepetes Paraskevi Liakou +2 位作者 Ioannis Balogiannis Maria Kouvaraki Konstantinos Hatzitheofilou 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第30期4776-4778,共3页
AIM: To evaluate a new technique of temporary ileal anastomotic stoma, following small bowel resection, in patients where the anastomosis is anticipated to have borderline margins with dubious viability. METHODS: Five... AIM: To evaluate a new technique of temporary ileal anastomotic stoma, following small bowel resection, in patients where the anastomosis is anticipated to have borderline margins with dubious viability. METHODS: Five patients underwent enterectomy and partially anastomosed end-loop ileostomy at the University Hospital of Larissa between 2000 and 2006. Enterectomy was performed because of conditions such as mesenteric vascular occlusive disease, radiation entritis and small bowel injury. RESULTS: Postoperatively, none of the patients developed any stoma-related or anastomotic complications. There were no major complications. All patients were discharged between the 8th and 15th day after the procedure, and the stoma was closed 3 wk to 4 wk later. CONCLUSION: We believe that our proposed modification of end-loop ileostomy is a simple, quick and safe technique with minimal stoma-related morbidity, and with simple and safe reversion. This technique can be considered as a useful option in the treatment of ischemic or radiation-induced enteritis, and in the management of severe intestinal trauma. 展开更多
关键词 Anastomotic stoma Loop ileostomy Ischemic enteritis radiation enteritis
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Failure mechanism and infrared radiation characteristic of hard siltstone induced by stratification effect 被引量:1
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作者 CHENG Yun SONG Zhanping +2 位作者 XU Zhiwei YANG Tengtian TIAN Xiaoxu 《Journal of Mountain Science》 SCIE CSCD 2024年第3期1058-1074,共17页
The deformation in sedimentary rock induced by train loads has potential threat to the safe operation of tunnels. This study investigated the influence of stratification structure on the infrared radiation and tempora... The deformation in sedimentary rock induced by train loads has potential threat to the safe operation of tunnels. This study investigated the influence of stratification structure on the infrared radiation and temporal damage mechanism of hard siltstone. The uniaxial compression tests, coupled with acoustic emission(AE) and infrared radiation temperature(IRT) were conducted on siltstones with different stratification effects. The results revealed that the stratigraphic structure significantly affects the stress-strain response and strength degradation characteristics. The mechanical parameters exhibit anisotropy characteristics, and the stratification effect exhibits a negative correlation with the cracking stress and peak stress. The failure modes caused by the stratification effect show remarkable anisotropic features, including splitting failure(Ⅰ: 0°-22.50°, Ⅱ: 90°), composite failure(45°), and shearing failure(67.50°). The AE temporal sequences demonstrate a stepwise response characteristic to the loading stress level. The AE intensity indicates that the stress sensitivity of shearing failure and composite failure is generally greater than that of splitting failure. The IRT field has spatiotemporal migration and progressive dissimilation with stress loading and its dissimilation degree increases under higher stress levels. The stronger the stratification effect, the greater the dissimilation degree of the IRT field. The abnormal characteristic points of average infrared radiation temperature(AIRT) variance at local stress drop and peak stress can be used as early and late precursors to identify fracture instability. Theoretical analysis shows that the competitive relationship between compaction strengthening and fracturing damage intensifies the dissimilation of the infrared thermal field for an increasing stress level. The present study provides a theoretical reference for disaster warnings in hard sedimentary rock mass. 展开更多
关键词 Hard siltstone Failure mechanism Stratification effect Infrared radiation characteristic Temporal-damage mechanism DISSIMILATION
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Simulation of the Ecosystem Productivity Responses to Aerosol Diffuse Radiation Fertilization Effects over the Pan-Arctic during 2001–19 被引量:1
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作者 Zhiding ZHANG Xu YUE +3 位作者 Hao ZHOU Jun ZHU Yadong LEI Chenguang TIAN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第1期84-96,共13页
The pan-Arctic is confronted with air pollution transported from lower latitudes.Observations have shown that aerosols help increase plant photosynthesis through the diffuse radiation fertilization effects(DRFEs).Whil... The pan-Arctic is confronted with air pollution transported from lower latitudes.Observations have shown that aerosols help increase plant photosynthesis through the diffuse radiation fertilization effects(DRFEs).While such DRFEs have been explored at low to middle latitudes,the aerosol impacts on pan-Arctic ecosystems and the contributions by anthropogenic and natural emission sources remain less quantified.Here,we perform regional simulations at 0.2o×0.2ousing a well-validated vegetation model(Yale Interactive terrestrial Biosphere,YIBs)in combination with multi-source of observations to quantify the impacts of aerosol DRFEs on the net primary productivity(NPP)in the pan-Arctic during 2001-19.Results show that aerosol DRFEs increase pan-Arctic NPP by 2.19 Pg C(12.8%)yr^(-1)under clear-sky conditions,in which natural and anthropogenic sources contribute to 8.9% and 3.9%,respectively.Under all-sky conditions,such DRFEs are largely dampened by cloud to only 0.26 Pg C(1.24%)yr^(-1),with contributions of 0.65% by natural and 0.59% by anthropogenic species.Natural aerosols cause a positive NPP trend of 0.022% yr^(-1)following the increased fire activities in the pan-Arctic.In contrast,anthropogenic aerosols induce a negative trend of-0.01% yr^(-1)due to reduced emissions from the middle latitudes.Such trends in aerosol DRFEs show a turning point in the year of 2007 with more positive NPP trends by natural aerosols but negative NPP trends by anthropogenic aerosols thereafter.Though affected by modeling uncertainties,this study suggests a likely increasing impact of aerosols on terrestrial ecosystems in the pan-Arctic under global warming. 展开更多
关键词 diffuse radiation fertilization effects anthropogenic aerosols natural aerosols pan-Arctic net primary productivity
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High-speed performance self-powered short wave ultraviolet radiation detectors based onκ(ε)-Ga_(2)O_(3) 被引量:1
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作者 Aleksei Almaev Alexander Tsymbalov +5 位作者 Bogdan Kushnarev Vladimir Nikolaev Alexei Pechnikov Mikhail Scheglov Andrei Chikiryaka Petr Korusenko 《Journal of Semiconductors》 EI CAS CSCD 2024年第4期56-62,共7页
High-speed solar-blind short wavelength ultraviolet radiation detectors based onκ(ε)-Ga_(2)O_(3)layers with Pt contacts were demonstrated and their properties were studied in detail.Theκ(ε)-Ga_(2)O_(3)layers were ... High-speed solar-blind short wavelength ultraviolet radiation detectors based onκ(ε)-Ga_(2)O_(3)layers with Pt contacts were demonstrated and their properties were studied in detail.Theκ(ε)-Ga_(2)O_(3)layers were deposited by the halide vapor phase epitaxy on patterned GaN templates with sapphire substrates.The spectral dependencies of the photoelectric properties of struc-tures were analyzed in the wavelength interval 200-370 nm.The maximum photo to dark current ratio,responsivity,detectiv-ity and external quantum efficiency of structures were determined as:180.86 arb.un.,3.57 A/W,1.78×10^(12) Hz^(0.5)∙cm·W^(-1) and 2193.6%,respectively,at a wavelength of 200 nm and an applied voltage of 1 V.The enhancement of the photoresponse was caused by the decrease in the Schottky barrier at the Pt/κ(ε)-Ga_(2)O_(3)interface under ultraviolet exposure.The detectors demon-strated could functionalize in self-powered mode due to built-in electric field at the Pt/κ(ε)-Ga_(2)O_(3)interface.The responsivity and external quantum efficiency of the structures at a wavelength of 254 nm and zero applied voltage were 0.9 mA/W and 0.46%,respectively.The rise and decay times in self-powered mode did not exceed 100 ms. 展开更多
关键词 κ(ε)-gallium oxide solar-blind shortwave ultraviolet radiation detectors self-powered operation mode
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Radiation of a TM mode from an open end of a three-layer dielectric capillary
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作者 Sergey NGalyamin Alexandr MAltmark 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期311-318,共8页
Modern trends in beam-driven radiation sources include the interaction of Cherenkov wakefields in open-ended circular waveguides with complicated dielectric linings, with a three-layer dielectric capillary recently pr... Modern trends in beam-driven radiation sources include the interaction of Cherenkov wakefields in open-ended circular waveguides with complicated dielectric linings, with a three-layer dielectric capillary recently proposed to reduce radiation divergence being a representative example [Opt. Lett. 45 5416(2020)]. We present a rigorous approach that allows for an analytical description of the electromagnetic processes that occur when the structure is excited by a single waveguide TM mode. In other words, the corresponding canonical waveguide diffraction problem is solved in a rigorous formulation. This is a continuation of our previous papers which considered simpler cases with a homogeneous or two-layer dielectric filling. Here we use the same analytical approach based on the Wiener–Hopf–Fock technique and deal with the more complicated case of a three-layer dielectric lining. Using the obtained rigorous solution, we discuss the possibility of manipulating the far-field radiation pattern using a third layer made of a low permittivity material. 展开更多
关键词 diffraction radiation open-ended waveguide Wiener–Hopf technique Cherenkov radiation
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Heuristic Estimation of the Vacuum Energy Density of the Universe: Part II-Analysis Based on Frequency Domain Electromagnetic Radiation
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作者 Vernon Cooray Gerald Cooray +1 位作者 Marcos Rubinstein Farhad Rachidi 《Journal of Electromagnetic Analysis and Applications》 2024年第1期1-9,共9页
In Part I of this paper, an inequality satisfied by the vacuum energy density of the universe was derived using an indirect and heuristic procedure. The derivation is based on a proposed thought experiment, according ... In Part I of this paper, an inequality satisfied by the vacuum energy density of the universe was derived using an indirect and heuristic procedure. The derivation is based on a proposed thought experiment, according to which an electron is accelerated to a constant and relativistic speed at a distance L from a perfectly conducting plane. The charge of the electron was represented by a spherical charge distribution located within the Compton wavelength of the electron. Subsequently, the electron is incident on the perfect conductor giving rise to transition radiation. The energy associated with the transition radiation depends on the parameter L. It was shown that an inequality satisfied by the vacuum energy density will emerge when the length L is pushed to cosmological dimensions and the product of the radiated energy, and the time duration of emission is constrained by Heisenberg’s uncertainty principle. In this paper, a similar analysis is conducted with a chain of electrons oscillating sinusoidally and located above a conducting plane. In the thought experiment presented in this paper, the behavior of the energy radiated by the chain of oscillating electrons is studied in the frequency domain as a function of the length L of the chain. It is shown that when the length L is pushed to cosmological dimensions and the energy radiated within a single burst of duration of half a period of oscillation is constrained by the fact that electromagnetic energy consists of photons, an inequality satisfied by the vacuum energy density emerges as a result. The derived inequality is given by where is the vacuum energy density. This result is consistent with the measured value of the vacuum energy density, which is 5.38 × 10<sup>-10</sup> J/m. The result obtained here is in better agreement with experimental data than the one obtained in Part I of this paper with time domain radiation. 展开更多
关键词 Classical Electrodynamics Electromagnetic radiation Action Radiated Energy PHOTON Heisenberg’s Uncertainty Principle Dark Energy Vacuum Energy Cosmological Constant Hubble Radius
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Progress of Radiation Belt Exploration by a Constellation of Small Satellites TGCSS/SGRB, COSPAR
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作者 WU Ji YANG Xiaochao +1 位作者 DAI Lei DENG Li 《空间科学学报》 CAS CSCD 北大核心 2024年第4期746-750,共5页
A COnstellation of Radiation BElt Survey(CORBES)program is proposed by the Sub-Group on Radiation Belt(SGRB)of TGCSS,COSPAR.To address the open qustions about the dynamics of the Earth’s radiation belt,CORBES mission... A COnstellation of Radiation BElt Survey(CORBES)program is proposed by the Sub-Group on Radiation Belt(SGRB)of TGCSS,COSPAR.To address the open qustions about the dynamics of the Earth’s radiation belt,CORBES mission would use a constellation of small/CubeSats to take an ultra-fast survey of the Earth’s radiation belt.The concept,science objectives and preliminary technical design of CORBES are introduced.This mission is an international multilateral cooperation mission coordinated by COSPAR.The SGRB Science Activities and COSPAR HQs Coordinate Activities on CORBES are summaried. 展开更多
关键词 radiation belts Ultra-fast survey CONSTELLATION
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Operando measurement of lattice deformation profiles of synchrotron radiation monochromator
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作者 Yue Zhang Zhong-Liang Li +4 位作者 Shang-Yu Si Lian Xue Hong-Xin Luo Xiao-Wei Zhang Jun Hu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第7期8-19,共12页
This study presents a new method for characterizing the thermal lattice deformation of a monochromator with high precision under service conditions and first reports the operando measurements of nanoscale thermal latt... This study presents a new method for characterizing the thermal lattice deformation of a monochromator with high precision under service conditions and first reports the operando measurements of nanoscale thermal lattice deformation on a double-crystal monochromator at different incident powers.The nanoscale thermal lattice deformation of the monochromator first crystal was obtained by analyzing the intensity of the distorted DuMond diagrams.DuMond diagrams of the 333 diffraction index,sensitive to lattice deformation,were obtained directly using a 2D detector and an analyzer crystal orthogonal to the monochromator.With increasing incident power and power density,the maximum height of the lattice deformation increased from 3.2 to 18.5 nm,and the deformation coefficient of the maximum height increased from 1.1 to 3.2 nm/W.The maximum relative standard deviation was 4.2%,and the maximum standard deviation was 0.1 nm.Based on the measured thermal deformations,the flux saturation phenomenon and critical point for the linear operation of the monochromator were predicted with increasing incident power.This study provides a simple solution to the problem of the lower precision of synchrotron radiation monochromator characterizations compared to simulations. 展开更多
关键词 Synchrotron radiation MONOCHROMATOR Lattice deformation X-ray dynamic diffraction
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Assessing the yield difference of double-cropping rice in South China driven by radiation use efficiency
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作者 Jian Lu Sicheng Deng +6 位作者 Muhammad Imran Jingyin Xie Yuanyuan Li Jianying Qi Shenggang Pan Xiangru Tang Meiyang Duan 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第11期3692-3705,共14页
Double-cropping rice in South China continues to break the total yield record,but the yield potential of singlecropping rice is not being realized.Radiation use efficiency(RUE)has been singled out as an important dete... Double-cropping rice in South China continues to break the total yield record,but the yield potential of singlecropping rice is not being realized.Radiation use efficiency(RUE)has been singled out as an important determinant of grain yield in many cereal species.However,there is no information on whether the yield gaps in doublecropping rice involve differences in RUE.Field experiments were performed over two years to evaluate the effects of intercepted radiation(IP)and RUE on the above-ground biomass production,crop growth rate(CGR),and harvest index(HI),in four representative rice varieties,i.e.,Xiangyaxiangzhan(XYXZ),Meixiangzhan 2(MXZ2),Nanjingxiangzhan(NJXZ),and Ruanhuayoujinsi(RHYJS),during the early and late seasons of rice cultivation in South China.The results revealed that grain yield in the early season was 8.2%higher than in the late season.The yield advantage in the early season was primarily due to higher spikelets per panicle and above-ground biomass resulting from a higher RUE.The spikelets per panicle in the early season were 6.5,8.3,6.9,and 8.5%higher in XYXZ,MXZ2,NJXZ,and RHYJS,respectively,than in the late season.The higher early season grain yield was more closely related to RUE in the middle tillering stage(R^(2)=0.34),panicle initiation(R^(2)=0.16),and maturation stage(R^(2)=0.28),and the intercepted photosynthetically active radiation(IPAR)in the maturation stage(R^(2)=0.28),while the late season grain yield was more dependent on IPAR in the middle tillering stage(R^(2)=0.31)and IPAR at panicle initiation(R^(2)=0.23).The results of this study conclusively show that higher RUE contributes to the yield progress of early season rice,while the yield improvement of late season rice is attributed to higher radiation during the early reproductive stage.Rationally allocating the RUE of double-cropping rice with high RUE varieties or adjustments of the sowing period merits further study. 展开更多
关键词 grain yield radiation use efficiency double-cropping rice
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Extraction of the key infrared radiation temperature features concerning stress and crack evolution of loaded rocks
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作者 Wei Liu Liqiang Ma +4 位作者 Michel Jaboyedoff Marc-Henri Derron Qiangqiang Gao Fengchang Bu Hai Sun 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第8期1059-1081,共23页
The infrared radiation temperature(IRT)variation concerning stress and crack evolution of rocks is a critical focus in rock mechanics domain and engineering disaster warning.In this paper,a methodology to extract the ... The infrared radiation temperature(IRT)variation concerning stress and crack evolution of rocks is a critical focus in rock mechanics domain and engineering disaster warning.In this paper,a methodology to extract the key IRT features related to stress and crack evolution of loaded rocks is proposed.Specifically,the wavelet denoising and reconstruction in thermal image sequence(WDRTIS)method is employed to eliminate temporal noise in thermal image sequences.Subsequently,the adaptive partition temperature drift correction(APTDC)method is introduced to alleviate temperature drift.On this basis,the spatial noise correction method based on threshold segmentation and adaptive median filtering(OTSU-AMF)is proposed to extract the key IRT features associated with microcracks of loaded rocks.Following temperature drift correction,IRT provides an estimation of the thermoelastic factor in rocks,typically around 5.29×10^(-5) MPa^(-1) for sandstones.Results reveal that the high-temperature concentrated region in cumulative thermal images of crack evolution(TICE)can elucidate the spatiotemporal evolution of localized damage.Additionally,heat dissipation of crack evolution(HDCE)acquired from TICE quantifies the progressive failure process of rocks.The proposed methodology enhances the reliability of IRT monitoring results and provides an innovative approach for conducting research in rock mechanics and monitoring engineering disasters. 展开更多
关键词 Infrared radiation(IR) Temperature drift Spatial background noise Rock fracture Average infrared radiation temperature(AIRT) Heat dissipation of crack evolution(HDCE)
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A Quasi-Linear Relationship between Planetary Outgoing Longwave Radiation and Surface Temperature in a Radiative-Convective-Transportive Climate Model of a Gray Atmosphere
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作者 Jie SUN Michael SECOR +1 位作者 Ming CAI Xiaoming HU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第1期8-18,共11页
In this study,we put forward a radiative-convective-transportive energy balance model of a gray atmosphere to examine individual roles of the greenhouse effect of water vapor,vertical convection,and atmospheric polewa... In this study,we put forward a radiative-convective-transportive energy balance model of a gray atmosphere to examine individual roles of the greenhouse effect of water vapor,vertical convection,and atmospheric poleward energy transport as well as their combined effects for a quasi-linear relationship between the outgoing longwave radiation(OLR)and surface temperature(T_(S)).The greenhouse effect of water vapor enhances the meridional gradient of surface temperature,thereby directly contributing to a quasi-linear OLR-T_(S) relationship.The atmospheric poleward energy transport decreases the meridional gradient of surface temperature.As a result of the poleward energy transport,tropical(high-latitude)atmosphere-surface columns emit less(more)OLR than the solar energy input at their respective locations,causing a substantial reduction of the meridional gradient of the OLR.The combined effect of reducing the meridional gradients of both OLR and surface temperature by the poleward energy transport also contributes to the quasi-linear OLR-T_(S) relationship.Vertical convective energy transport reduces the meridional gradient of surface temperature without affecting the meridional gradient of OLR,thereby suppressing part of the reduction to the increasing rate of OLR with surface temperature by the greenhouse effect of water vapor and poleward energy transport.Because of the nature of the energy balance in the climate system,such a quasi-linear relationship is also a good approximation for the relationship between the annual-mean net downward solar energy flux at the top of the atmosphere and surface temperature. 展开更多
关键词 outgoing longwave radiation greenhouse effect poleward energy transport
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Predicting microseismic,acoustic emission and electromagnetic radiation data using neural networks
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作者 Yangyang Di Enyuan Wang +3 位作者 Zhonghui Li Xiaofei Liu Tao Huang Jiajie Yao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第2期616-629,共14页
Microseism,acoustic emission and electromagnetic radiation(M-A-E)data are usually used for predicting rockburst hazards.However,it is a great challenge to realize the prediction of M-A-E data.In this study,with the ai... Microseism,acoustic emission and electromagnetic radiation(M-A-E)data are usually used for predicting rockburst hazards.However,it is a great challenge to realize the prediction of M-A-E data.In this study,with the aid of a deep learning algorithm,a new method for the prediction of M-A-E data is proposed.In this method,an M-A-E data prediction model is built based on a variety of neural networks after analyzing numerous M-A-E data,and then the M-A-E data can be predicted.The predicted results are highly correlated with the real data collected in the field.Through field verification,the deep learning-based prediction method of M-A-E data provides quantitative prediction data for rockburst monitoring. 展开更多
关键词 MICROSEISM Acoustic emission Electromagnetic radiation Neural networks Deep learning ROCKBURST
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Potential pharmacological mechanisms of digallate in the treatment of enteritis based on network pharmacology and molecular docking
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作者 Ning Tang Lian-Dong Zhao +3 位作者 Yang Zhao Yu-Meng Han Yue Cao Yan Wang 《Integrative Medicine Discovery》 2024年第7期1-10,共10页
Background:In order to investigate the possible pharmacological mechanism of digallate in Galla Chinensis for treating enteritis,providing reference for the search and exploration of effective drugs for treating enter... Background:In order to investigate the possible pharmacological mechanism of digallate in Galla Chinensis for treating enteritis,providing reference for the search and exploration of effective drugs for treating enteritis.Method:Traditional Chinese Medicines Systems Pharmacology Database and Analysis Platform,PharmMapper,DisGeNET,DrugBank,and GeneCards databases were used to obtain drug and disease-related target information.Gene ontology functional annotation and Kyoto Encyclopedia of Genes and Genomes pathway enrichment were performed,and the main therapeutic pathways and targets were identified by combining protein-protein interaction networks and cytoHubba plug-in.Molecular docking was used to validate the results.Result:297 drug related targets,2436 disease related targets,and 66 target points related to digallate were predicted to be associated with enteritis.10 related signal pathways and 10 key genes were identified.Conclusion:Digallate may be utilized to treat enteritis by acting on similar pathways,such those related to pathways in cancer,lipid and atherosclerosis,proteoglycans in cancer,Rap1 signaling pathway,PI3K-Akt signaling pathway and other targets such as IGF1,EGFR,SRC,IGF1R,PPARG. 展开更多
关键词 digallate enteritis network pharmacology molecular docking
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Scheme of negative acoustic radiation force based on a multiple-layered spherical structure
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作者 宫门阳 徐鑫 +3 位作者 乔玉配 刘杰惠 何爱军 刘晓宙 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第1期477-487,共11页
Acoustic radiation force(ARF), as an important particle manipulation method, has been extensively studied in recent years. With the introduction of the concept of “acoustic tweezers”, negative acoustic radiation has... Acoustic radiation force(ARF), as an important particle manipulation method, has been extensively studied in recent years. With the introduction of the concept of “acoustic tweezers”, negative acoustic radiation has become a research hotspot. In this paper, a scheme of realizing negative ARF based on the multiple-layered spherical structure design is proposed. The specific structure and design idea are presented. Detailed theoretical calculation analysis is carried out.Numerical simulations have been performed to verify the correctness of this prediction. The conjecture that the suppression of backscattering can achieve negative ARF is verified concretely, which greatly expands the application prospect and design ideas of the ARF. This work has laid a theoretical foundation for realizing precise control of the structure. 展开更多
关键词 acoustic tweezers negative acoustic radiation force particle manipulation
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Isomeric fluorescence sensors for wide range detection of ionizing radiations
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作者 Jimin Han Tianyu Yang +1 位作者 Li Yang Yuanjian Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期247-257,共11页
In order to achieve a wider range of ionizing radiations detection,novel fluorescence sensing materials have been developed that utilize the fluorescence enhancement phenomenon caused by the intramolecular photoinduce... In order to achieve a wider range of ionizing radiations detection,novel fluorescence sensing materials have been developed that utilize the fluorescence enhancement phenomenon caused by the intramolecular photoinduced electron transfer(PET)effect.Two perylene diimide isomers PDI-P and PDI-B were designed and synthesized,and their molecular structures were characterized by high-resolution Fourier transform mass spectrometry(HRMS),nuclear magnetic resonance hydrogen and carbon spectroscopy(~1H and~(13)C NMR).The interaction between ionizing radiation and fluorescent molecules was simulated by HCl titration.The results show that combining PDIs and HCl can improve fluorescence through the retro-PET process.Despite the similarities in chemical structures,the fluorescent enhancement multiple of PDI-B with aromatic amine as electron donor is much higher than that of PDI-P with alkyl amine.In the direct irradiation experiments of ionizing radiation,the emission enhancement multiples of PDI-P and PDI-B are 2.01 and 45.4,respectively.Furthermore,density functional theory(DFT)and time-dependent density functional theory(TDDFT)calculations indicate that the HOMO and HOMO-1 energy ranges of PDI-P and PDI-B are 0.54 e V and 1.13 e V,respectively.A wider energy range has a stronger driving force on electrons,which is conducive to fluorescence quenching.Both femtosecond transient absorption spectroscopy(fs-TAS)and transient fluorescence spectroscopy(TFS)tests show that PDI-B has shorter charge separation lifetime and higher electron transfer rate constant.Although both isomers can significantly reduce LOD during PET process,PDI-B with aromatic amine has a wider detection range of 0.118—240 Gy due to its larger emission enhancement,which is a leap of three orders of magnitude.It breaks through the detection range of gamma radiation reported in existing studies,and provides theoretical support for the further study of sensitive and effective new materials for ionizing radiation detection. 展开更多
关键词 Perylene imide Intramolecular PET Ionizing radiation detection Fluorescence sensor ISOMERS
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The Performance of Downward Shortwave Radiation Products from Satellite and Reanalysis over the Transect of Zhongshan Station to Dome A, East Antarctica
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作者 Jiajia JIA Zhaoliang ZENG +3 位作者 Wenqian ZHANG Xiangdong ZHENG Yaqiang WANG Minghu DING 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第8期1574-1588,1671-1675,共20页
The downward shortwave radiation(DSR) is an important part of the Earth's energy balance, driving Earth's system's energy, water, and carbon cycles. Due to the harsh Antarctic environment, the accuracy of ... The downward shortwave radiation(DSR) is an important part of the Earth's energy balance, driving Earth's system's energy, water, and carbon cycles. Due to the harsh Antarctic environment, the accuracy of DSR derived from satellite and reanalysis has not been systematically evaluated over the transect of Zhongshan station to Dome A, East Antarctica.Therefore, this study aims to evaluate DSR reanalysis products(ERA5-Land, ERA5, MERRA-2) and satellite products(CERES and ICDR) in this area. The results indicate that DSR exhibits obvious monthly and seasonal variations, with higher values in summer than in winter. The ERA5-Land(ICDR) DSR product demonstrated the highest(lowest) accuracy,as evidenced by a correlation coefficient of 0.988(0.918), a root-mean-square error of 23.919(69.383) W m^(–2), a mean bias of –1.667(–28.223) W m^(–2) and a mean absolute error of 13.37(58.99) W m^(–2). The RMSE values for the ERA5-Land reanalysis product at seven stations, namely Zhongshan, Panda 100, Panda 300, Panda 400, Taishan, Panda 1100, and Kunlun, were 30.938, 29.447, 34.507, 29.110, 20.339, 17.267, and 14.700 W m^(-2), respectively;with corresponding bias values of 9.887, –12.159, –19.181, –15.519, –8.118, 6.297, and 3.482 W m^(–2). Regarding seasonality, ERA5-Land, ERA5,and MERRA-2 reanalysis products demonstrate higher accuracies during spring and summer, while ICDR products are least accurate in autumn. Cloud cover, water vapor, total ozone, and severe weather are the main factors affecting DSR. The error of DSR products is greatest in coastal areas(particularly at the Zhongshan station) and decreases towards the inland areas of Antarctica. 展开更多
关键词 downward shortwave radiation East Antarctic reanalysis product satellite product validation
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A Study of Radiation-Induced Telomere Instability Using Multiplex Ligation-Dependent Probe Amplification (MLPA)
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作者 Alan Chant Ahmad Chaudary Christina M. Kraemer-Chant 《Advances in Biological Chemistry》 CAS 2024年第3期73-85,共13页
The integrity of the chromosomes for two WIL2-derived lymphoblastoid cell lines (TK6 and WTK1) in the presence and absence of ionizing radiation was analyzed by Multiplex Ligation-Dependent Probe Amplification (MLPA).... The integrity of the chromosomes for two WIL2-derived lymphoblastoid cell lines (TK6 and WTK1) in the presence and absence of ionizing radiation was analyzed by Multiplex Ligation-Dependent Probe Amplification (MLPA). The TK6 cell line has the native p53 tumor-suppressor gene, whereas WTK1 cells contain a p53 mutation. Each cell line was isolated pre- and post-irradiation (2 and 3 Gy) and analyzed by MLPA. The impact of irradiation on these two cell lines was investigated using probes that target specific regions on chromosomes associated with subtelomeric regions. Results indicate that WTK1 and TK6 are impacted differently after irradiation, and that each cell line presents its own unique MLPA profile. The most notable differences are the appearance of a number of probes in the post-irradiated MLPA profile that are not present in the controls, and two unique probe signals only seen in WTK1 cells. These results build on our previous studies that indicate how different human cell lines can be affected by radiation in significantly different ways depending on the presence or absence of wild type p53. 展开更多
关键词 Ionizing radiation Multiplex Ligation-Dependent Probe Amplification (MLPA) p53 Tumor Suppressor Telomere Instability
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Effect of combination of ultraviolet radiation and biocide on fungal-induced corrosion of high-strength 7075 aluminum alloy
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作者 Zheng-yu JIN Chao WANG +1 位作者 Hai-xian LIU Hong-wei LIU 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第9期2787-2799,共13页
The effect of ultraviolet(UV)radiation and biocide benzalkonium chloride(BKC)on fungal-induced corrosion of AA7075 induced by Aspergillus terreus(A.terreus)was deeply studied using analysis of biological activity,surf... The effect of ultraviolet(UV)radiation and biocide benzalkonium chloride(BKC)on fungal-induced corrosion of AA7075 induced by Aspergillus terreus(A.terreus)was deeply studied using analysis of biological activity,surface analysis,and electrochemical measurements.Results demonstrated that the planktonic and sessile spore concentrations decline by more than two orders of magnitude when UV radiation and BKC are combinedly used compared with the control.UV radiation can inhibit the biological activity of A.terreus and influence the stability of passive film of AA7075.Except for direct disinfection,the physical adsorption of BKC on the specimen can effectively inhibit the attachment of A.terreus.The combination of UV radiation and BKC can much more effectively inhibit the corrosion of AA,especially pitting corrosion,due to their synergistic effect.The combined application of UV radiation and BKC can be a good method to effectively inhibit fungal-induced corrosion. 展开更多
关键词 fungal-induced corrosion Aspergillus terreus 7075 aluminum alloy ultraviolet radiation benzalkonium chloride
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