Background context:Metastatic spinal cord compression(MSCC)seriously affects the survival rate.Objective:The therapeutic effects of two treatment strategies for MSCC:percutaneous vertebroplasty(PVP)combined with radio...Background context:Metastatic spinal cord compression(MSCC)seriously affects the survival rate.Objective:The therapeutic effects of two treatment strategies for MSCC:percutaneous vertebroplasty(PVP)combined with radiofrequency ablation(RFA)and PVP combined with^(125)I particle implantation,were compared.Study design:Retrospective study.Patient sample:40 patients with MSCC were divided into two groups:19 cases in the RFA group and 21 cases in the^(125)I group.Method:All patients were accessed to determine the differences in pain,which was evaluated using the visual analog scale(VAS)at 1 week,1 month,and 3 months after the operation,and spinal stenosis rates(SSRs),which were measured at 1 and 3 months after the operation,between the two groups.Results:The VAS scores and SSRs at baseline were comparable between the RFA group and the^(125)I group(7.19±2.07 vs 7.42±1.95,37.7%±11.2%vs 41.1%±11.4%).The VAS scores and SSRs at 1 month and 3 months after the operation were significantly reduced in both groups,compared with those at baseline.The VAS scores and SSRs in the^(125)I group were lower than those in the RFA group at 3 months after the operation(1.09±0.97 vs 1.75±1.06 p=0.048 and 12.3%±6.4%vs 18.1%±10.1%p=0.034),while the VAS scores at1 week after the operation in the RFA group were lower than those in the^(125)I group(4.39±1.34 vs 5.05±1.82 p=0.049).Conclusion:PVP combined with RFA has a slight advantage in relieving pain in the short term,while PVP combined with^(125)I particle implantation may have a better effect in the relieving pain and decreasing the SSRs at 3 months after the operation.展开更多
Background: Trigeminal neuralgia is a chronic pain syndrome characterized by paroxysmal, shock-like, stabbing, recurrent episodes of pain localized in the distribution area of one or more branches of the trigeminal ne...Background: Trigeminal neuralgia is a chronic pain syndrome characterized by paroxysmal, shock-like, stabbing, recurrent episodes of pain localized in the distribution area of one or more branches of the trigeminal nerve. The Initial approach for treating trigeminal neuralgia consists of pharmacological therapy. Many patients experience initial pain relief with pharmacological therapy;however, most of those patients eventually undergo surgery. Patients and Methods: In this descriptive prospective study, we evaluate the efficiency and safety of percutaneous balloon compression (PBC) and percutaneous radiofrequency ablation (RFA) in treating patients with typical idiopathic trigeminal neuralgia. This study includes 21 patients (divided into two groups, PBC = 15 patients and RFA = six patients) who met our inclusion and exclusion criteria, from May 2018 to April 2019, with a follow-up period of six months. Results: At one month postoperative follow-up, all patients in both groups were pain-free. At six months postoperative follow-up, in group 1 (PBC), 14 (95.24%) patients were pain-free, while in group 2 (RFA) all patients remained pain-free. The most common encountered postoperative complications are masticatory muscles weakness (Four patients in PBC group, and one patient in RFA group) and facial hypothesia (12 patients in PBC group and four patients in RFA group). Conclusions: In our study, patients with trigeminal neuralgia were not controlled by drug treatment, but percutaneous balloon compression and percutaneous radiofrequency ablation proved to be very effective treatment options, with no major complications.展开更多
文摘Background context:Metastatic spinal cord compression(MSCC)seriously affects the survival rate.Objective:The therapeutic effects of two treatment strategies for MSCC:percutaneous vertebroplasty(PVP)combined with radiofrequency ablation(RFA)and PVP combined with^(125)I particle implantation,were compared.Study design:Retrospective study.Patient sample:40 patients with MSCC were divided into two groups:19 cases in the RFA group and 21 cases in the^(125)I group.Method:All patients were accessed to determine the differences in pain,which was evaluated using the visual analog scale(VAS)at 1 week,1 month,and 3 months after the operation,and spinal stenosis rates(SSRs),which were measured at 1 and 3 months after the operation,between the two groups.Results:The VAS scores and SSRs at baseline were comparable between the RFA group and the^(125)I group(7.19±2.07 vs 7.42±1.95,37.7%±11.2%vs 41.1%±11.4%).The VAS scores and SSRs at 1 month and 3 months after the operation were significantly reduced in both groups,compared with those at baseline.The VAS scores and SSRs in the^(125)I group were lower than those in the RFA group at 3 months after the operation(1.09±0.97 vs 1.75±1.06 p=0.048 and 12.3%±6.4%vs 18.1%±10.1%p=0.034),while the VAS scores at1 week after the operation in the RFA group were lower than those in the^(125)I group(4.39±1.34 vs 5.05±1.82 p=0.049).Conclusion:PVP combined with RFA has a slight advantage in relieving pain in the short term,while PVP combined with^(125)I particle implantation may have a better effect in the relieving pain and decreasing the SSRs at 3 months after the operation.
文摘Background: Trigeminal neuralgia is a chronic pain syndrome characterized by paroxysmal, shock-like, stabbing, recurrent episodes of pain localized in the distribution area of one or more branches of the trigeminal nerve. The Initial approach for treating trigeminal neuralgia consists of pharmacological therapy. Many patients experience initial pain relief with pharmacological therapy;however, most of those patients eventually undergo surgery. Patients and Methods: In this descriptive prospective study, we evaluate the efficiency and safety of percutaneous balloon compression (PBC) and percutaneous radiofrequency ablation (RFA) in treating patients with typical idiopathic trigeminal neuralgia. This study includes 21 patients (divided into two groups, PBC = 15 patients and RFA = six patients) who met our inclusion and exclusion criteria, from May 2018 to April 2019, with a follow-up period of six months. Results: At one month postoperative follow-up, all patients in both groups were pain-free. At six months postoperative follow-up, in group 1 (PBC), 14 (95.24%) patients were pain-free, while in group 2 (RFA) all patients remained pain-free. The most common encountered postoperative complications are masticatory muscles weakness (Four patients in PBC group, and one patient in RFA group) and facial hypothesia (12 patients in PBC group and four patients in RFA group). Conclusions: In our study, patients with trigeminal neuralgia were not controlled by drug treatment, but percutaneous balloon compression and percutaneous radiofrequency ablation proved to be very effective treatment options, with no major complications.
