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Random Channel Allocation Scheme for SDMA Systems 被引量:1
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作者 邓燕 方旭明 《Journal of Southwest Jiaotong University(English Edition)》 2005年第2期135-138,共4页
A random allocation scheme for SDMA systems is proposed with a goal of more efficient dynamic allocation. Based on theoretical analysis and derivation, the blocking probability of the proposed scheme is calculated and... A random allocation scheme for SDMA systems is proposed with a goal of more efficient dynamic allocation. Based on theoretical analysis and derivation, the blocking probability of the proposed scheme is calculated and compared with those of the ftrst duplicate (FD) and duplicate last (DL) schemes with different state-independent probabilities (p,) of acquring a dupicate channel suecessfully and 5 resources; moreover, a more realistic performance analysis of the random scheme is made with state-dependent ps in the SDMA/CDMA environment. The results show that the random scheme has a similar allocation pefformace to the FD and DL schemes, but is simpler than them in computation and scheduling. 展开更多
关键词 random channel allocation SDMA Blocking probability
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Analysis of Methodology for the Application of Stratified Random Sampling with Optimum Allocation: The Case Study of Forest Bioenergy
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作者 M.N.Tsatiris 《Journal of Environmental Science and Engineering(A)》 2012年第1期82-91,共10页
In this paper, analysis of methodology was realized for the application of stratified random sampling with optimum allocation in the case of a subject of research which concerns the rural population and presents high ... In this paper, analysis of methodology was realized for the application of stratified random sampling with optimum allocation in the case of a subject of research which concerns the rural population and presents high differentiations among the three strata in which this population could be classified. The rural population of Evros Prefecture (Greece) with criterion the mean altitude of settlements was classified in three strata, the mountainous, semi-mountainous and fiat population for the estimation of mean consumption of forest fuelwood for covering of heating and cooking needs in households of these three strata. The analysis of this methodology includes: (1) the determination of total size of sample for entire the rural population and its allocation to the various strata; (2) the investigation of effectiveness of stratification with the technique of analysis of variance (One-Way ANOVA); (3) the conduct of sampling research with the realization of face-to-face interviews in selected households and (4) the control of forms of the questionnaire and the analysis of data by using the statistical package for social sciences, SPSS for Windows. All data for the analysis of this methodology and its practical application were taken by the pilot sampling which was realized in each stratum. Relative paper was not found by the review of literature. 展开更多
关键词 Analysis of methodology stratified random sampling with optimum allocation rural population forest bioenergy.
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Randomized MILP framework for Securing Virtual Machines from Malware Attacks
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作者 R.Mangalagowri Revathi Venkataraman 《Intelligent Automation & Soft Computing》 SCIE 2023年第2期1565-1580,共16页
Cloud computing involves remote server deployments with public net-work infrastructures that allow clients to access computational resources.Virtual Machines(VMs)are supplied on requests and launched without interacti... Cloud computing involves remote server deployments with public net-work infrastructures that allow clients to access computational resources.Virtual Machines(VMs)are supplied on requests and launched without interactions from service providers.Intruders can target these servers and establish malicious con-nections on VMs for carrying out attacks on other clustered VMs.The existing system has issues with execution time and false-positive rates.Hence,the overall system performance is degraded considerably.The proposed approach is designed to eliminate Cross-VM side attacks and VM escape and hide the server’s position so that the opponent cannot track the target server beyond a certain point.Every request is passed from source to destination via one broadcast domain to confuse the opponent and avoid them from tracking the server’s position.Allocation of SECURITY Resources accepts a safety game in a simple format as input andfinds the best coverage vector for the opponent using a Stackelberg Equilibrium(SSE)technique.A Mixed Integer Linear Programming(MILP)framework is used in the algorithm.The VM challenge is reduced by afirewall-based controlling mechanism combining behavior-based detection and signature-based virus detection.The pro-posed method is focused on detecting malware attacks effectively and providing better security for the VMs.Finally,the experimental results indicate that the pro-posed security method is efficient.It consumes minimum execution time,better false positive rate,accuracy,and memory usage than the conventional approach. 展开更多
关键词 Virtualization technology security cross-VM channel attack VM-escape R-VM-MILP algorithm(randomized VM allocation of security resources) Mixed Integer Linear Programming(MILP) SSE strategy firewall-based monitoring method
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Assessment of duodenogastric reflux by combined continuous intragastric pH and bilirubin monitoring 被引量:30
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作者 Fei Dai Jun Gong Ru Zhang Jin-Yan Luo You-Ling Zhu Xue-Qin Wang,Department of Gastroenterology,Second Hospital of Xi’ an Jiaotong University,Xi’an 710004,Shaanxi Province,China 《World Journal of Gastroenterology》 SCIE CAS CSCD 2002年第2期382-384,共3页
AIM: To assess the diagnostic value of a combination of continuous intragastric pH and bilirubin monitoring in the detection of duodenogastric reflux (DGR), and the effects of diet on the bilirubin absorbance. METHODS... AIM: To assess the diagnostic value of a combination of continuous intragastric pH and bilirubin monitoring in the detection of duodenogastric reflux (DGR), and the effects of diet on the bilirubin absorbance. METHODS: 30 healthy volunteers were divided into two groups: standard diet group (Group 1) 18 cases, free diet group (Group 2)12 cases. Each subjects were subjected to simultaneous 24-hour intragastric pH and spectrophotometric bilirubin concentration monitoring (Bilitec 2000). RESULTS: There was no difference of preprandial phase bilirubin absorbance between two groups. The absorbance of postprandial phase was significantly increased in group 2 than group 1. There was no difference between preprandial phase and postprandial phase absorbance in group 1. Postprandial phase absorbance was significantly higher in group 2. In a comparison of bile reflux with intragastric pH during night time, there were 4 types of reflux: Simultaneous increase in absorbance and pH in only 19.6%, increase in bilirubin with unchanged pH 33.3%, pH increase with unchanged absorbance 36.3%, and both unchanged in 10.8%. Linear regression analysis showed no correlation between percentage total time of pH【4 and percentage total time of absorbance】0.14, r=0.068 P【0.05. CONCLUSION: Because of the dietary effect, high absorbance fluids or foods should be avoided in detection. Intragastric pH and bilirubin monitoring separately predict the presence of duodenal (and/or pancreatic) reflux and bile reflux. They can not substitute for each other. The detection of DGR is improved if the two parameters are combined simultaneously. 展开更多
关键词 ADULT Aged BILIRUBIN DIET Duodenogastric Reflux FEMALE Fiber Optics Humans Hydrogen-Ion Concentration Male Middle Aged Postprandial Period random allocation Research Support Non-U.S. Gov't
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Effect of L-NAME on nitric oxide and gastrointestinal motility alterations in cirrhotic rats 被引量:19
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作者 Xin Wang Zong-You Zhang Mei Lan Ji-Yan Miao Xue-Gang Guo Yong-Quan Shi Yan-Qiu Zhao Jie Ding Kai-Cun Wu Dai-Ming Fan,Institute of Digestive disease,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China Yue-Xia Zhong,Emergency Department,Tangdu Hospital,Fourth Military Medical University,Xi’an 710038,Shaanxi Province,China Ju Lu,Class EE 87,Department of Electronic Engineering,Tsinghua University,Beijing 100084,China Bo-Rong Pan,Oncology Center,Xijing Hospital,Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China 《World Journal of Gastroenterology》 SCIE CAS CSCD 2002年第2期328-332,共5页
AIM: To investigate the effect of L-NAME on nitric oxide and gastrointestinal motility alterations in cirrhotic rats. METHODS: Rats with cirrhosis induced by carbon tetrachloride were randomly divided into two groups,... AIM: To investigate the effect of L-NAME on nitric oxide and gastrointestinal motility alterations in cirrhotic rats. METHODS: Rats with cirrhosis induced by carbon tetrachloride were randomly divided into two groups, one n =13 receiving 0.5mg.kg(-1) per day of N(G)-nitro-L-arginine methyl ester (L-NAME), a nitric oxide synthase inhibitor, for 10 days, whereas the other group (n =13) and control (n =10) rats were administrated the same volume of 9g.L(-1) saline. Half gastric emptying time and 2h residual rate were measured by SPECT, using (99m)Tc-DTPA-labeled barium sulfate as test meal. Gastrointestinal transition time was recorded simultaneously. Serum concentration of nitric oxide (NO) was determined by the kinetic cadmium reduction and colorimetric methods. Immunohistochemical SABC method was used to observe the expression and distribution of three types of nitric oxide synthase (NOS) isoforms in the rat gastrointestinal tract. Western blot was used to detect expression of gastrointestinal NOS isoforms. RESULTS: Half gastric emptying time and trans-gastrointestinal time were significantly prolonged(124.0 +/- 26.4 min; 33.7 +/- 8.9 min; 72.1 +/- 15.3 min; P【0.01), (12.4 +/- 0.5h; 9.5 +/- 0.3h; 8.2 +/- 0.8h; P【0.01), 2h residual rate was raised in cirrhotic rats than in controls and cirrhotic rats treated with L-NAME (54.9 +/- 7.6%,13.7 +/- 3.2%, 34.9 +/- 10.3%, P【0.01). Serum concentration of NO was significantly increased in cirrhotic rats than in the other groups (8.20 +/- 2.48) micromol.L(-1), (5.94 +/-1.07) micromol.L(-1) and control (5.66 +/- 1.60 micromol.L(-1), P【0.01. NOS staining intensities which were mainly located in the gastrointestinal tissues were markedly lower in cirrhotic rats than in the controls and cirrhotic rats after treated with L-NAME. CONCLUSION: Gastrointestinal motility was remarkably inhibited in cirrhotic rats, which could be alleviated by L-NAME. Nitric oxide may play an important role in the inhibition of gastrointestinal motility in cirrhotic rats. 展开更多
关键词 Animals Carbon Tetrachloride Digestive System Enzyme Inhibitors Gastrointestinal Motility Humans Liver Cirrhosis Experimental Male NG-Nitroarginine Methyl Ester Nitric Oxide Nitric Oxide Synthase random allocation RATS Rats Sprague-Dawley Research Support Non-U.S. Gov't Tomography Emission-Computed Single-Photon
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Effects of progesterone on gastric emptying and intestinal transit in male rats 被引量:12
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作者 Paulus S.Wang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2002年第2期338-341,共4页
AIM: To study the dose-dependent of progesterone (P) effect and the interaction between the oxytocin (OT) and P on gastrointestinal motility. METHODS: In order to monitor the gastric emptying and intestinal transit, t... AIM: To study the dose-dependent of progesterone (P) effect and the interaction between the oxytocin (OT) and P on gastrointestinal motility. METHODS: In order to monitor the gastric emptying and intestinal transit, the SD male rats were intubated via a catheter with normal saline (3 ml/kg) containing Na(2)(51)CrO(4) (0.5 microCi/ml) and 10% charcoal. OT was dissolved into normal saline and P was dissolved into 75% alcohol. RESULTS: Low does of P (1 mg/kg, i.p.) enhanced the gastric emptying (75+/-3%, P【0.05) and high dose of P (5 mg/kg, i.p.) inhibit it (42+/-11.2%, P【0.01). P (1 mg/kg) increased the intestinal transit (4.2+/-0.3, P【0.05) while the higher dose (10-20 mg/kg) had no effect. OT (0.8 mg/kg, i.p.) inhibited the gastric emptying (23.5+/-9.8%, P【0.01). The inhibitory effects of P(20 mg/kg) (32+/-9.7%, P【0.05) and OT (0.8 mg/kg) on gastric emptying enhanced each other when the two chemicals were administrated simultaneously (17+/-9.4%, P【0.01). CONCLUSION: Low dose of P increased GI motility while high dose of P decreased it. During the later period of pregnancy, elevated plasma level of OT may also participate in the gastrointestinal inhibition. 展开更多
关键词 ANIMALS Drug Interactions Gastric Emptying Gastrointestinal Transit Male OXYTOCIN PROGESTERONE random allocation RATS Rats Sprague-Dawley Research Support Non-U.S. Gov't
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Study on Action of Acupuncture on Ventromedial Nucleus of Hypothalamus in Obese Rats 被引量:10
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作者 刘志诚 孙凤岷 +7 位作者 苏静 赵玫 朱苗花 王沂争 魏群利 李嘉 顾云 王友京 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第3期220-224,共5页
Effects of acupuncture on the spontaneous discharge of nerve cells and levels of monoamine neurotransmitters in ventromedial nucleus of hypothalamus (VMH) of the obese rats were investigated. Results indicated that th... Effects of acupuncture on the spontaneous discharge of nerve cells and levels of monoamine neurotransmitters in ventromedial nucleus of hypothalamus (VMH) of the obese rats were investigated. Results indicated that the levels of tyrosine (Tyr) and dopamine (DA) were lowered, the levels of 5-hydroxytryptamine (5-HT) and 5-hydoxyindole acetic acid (5-HIAA) increased, and the frequency of the spontaneous discharge of nerve cells in VMH lowered in the obese rat group as compared with the normal group. When acupuncture obtained the effect of weight reduction, the frequency of spontaneous discharges of nerve cells in VMH were markedly increased, and the levels of Tyr, DA and tryptamine (Typ) and 5-HT/5-HIAA ratio elevated, and the 5-HT level lowered. It is suggested that the virtuous regulative action of acupuncture on VMH might be one of the key factors in acupuncture for weight reduction. 展开更多
关键词 ACUPUNCTURE Animals Dopamine HYPOTHALAMUS Male Obesity random allocation RATS Rats Sprague-Dawley SEROTONIN TYROSINE Ventromedial Hypothalamic Nucleus
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Regulating effect of Chinese herbal medicine on the peritoneal lymphatic stomata in enhancing ascites absorption of experimental hepatofibrotic mice 被引量:10
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作者 Ji-Cheng Li Shi-Ping Ding,Department of Lymphology,Department of Histology and Embryology, Medical College of Zhejiang University,Hangzhou 310031,Zhejiang Province,China Jian Xu,Hangzhou First People’ s Hospital,Hangzhou 310006,Zhejiang Province,China 《World Journal of Gastroenterology》 SCIE CAS CSCD 2002年第2期333-337,共5页
AIM: To observe the regulatory effect of Chinese herbal medicine on peritoneal lymphatic stomata and its significance in treating ascites in liver fibrosis model mice. METHODS: Two Chinese herbal composite prescriptio... AIM: To observe the regulatory effect of Chinese herbal medicine on peritoneal lymphatic stomata and its significance in treating ascites in liver fibrosis model mice. METHODS: Two Chinese herbal composite prescriptions were used separately to treat the carbon tetrachloride-induced mouse model of liver fibrosis. The histo-pathologic changes of the liver sections (HE and VG stainings) were observed. The peritoneal lymphatic stomata was detected by scanning electron microscopy and computer image processing. The changes of urinary volume and sodium ion concentration were measured. RESULTS: In the model group, lots of fibrous tissue formed in liver and extended into the hepatic lobules to separate them incompletely. In the treated and prevention groups, the histo-pathologic changes of liver was rather milder, only showed much less fibrous tissue proliferation in the hepatic lobules. The peritoneal lymphatic stomata enlarged with increased density in the experimental groups (diameter: PA, 3.07 +/- 0.69 microm; PB, 2.82 +/- 0.37 microm; TA, 3.25 +/- 0.82 microm and TB, 2.82 +/- 0.56 microm; density: PA, 7.11 +/- 1.90 stomata.1000 microm(-2); PB, 8.76 +/- 1.45 stomata.1000 microm(-2); TA, 6.55 +/- 1.44 stomata.1000 microm(-2)and TB, 8.76+/-1.79 stomata.1000 microm(-2)), as compared with the model group (diameter: 2.00+/-0.52 microm density: 4.45+/-1.05 stomata.1000 microm(-2)). After treatment, the urinary volume and sodium ion excretion increased in the experimental groups (PA, 231.28+/-41.09 mmol.L(-1); PB, 171.69 +/- 27.48 mmol.L(-1) and TA, 231.44 +/- 34.12 mmol.L(-1)), which were significantly different with those in the model group (129.33 +/- 36.75 mmol.L(-1)). CONCLUSION: Chinese herbal medicine has marked effects in alleviating liver fibrosis, regulating peritoneal lymphatic stomata, improving the drainage of ascites from peritoneal cavity and causing increase of urinary volume and sodium ion excretion to reduce the water and sodium retention, and thus have favorable therapeutic effect in treating ascites. 展开更多
关键词 PHYTOTHERAPY Animals ASCITES Carbon Tetrachloride Chlorides Drugs Chinese Herbal Liver Liver Cirrhosis Experimental Lymph Nodes Male Medicine Chinese Traditional MICE PERITONEUM Potassium random allocation Research Support Non-U.S. Gov't Sodium
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Interobserver variation in histopathological assessment of Helicobacter pylori gastritis 被引量:6
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作者 Ozlem Aydin Reyhan Egilmez +1 位作者 Tuba Karabacak Arzu Kanik 《World Journal of Gastroenterology》 SCIE CAS CSCD 2003年第10期2232-2235,共4页
AIM:Because the presence or absence of H pylori infection has important implications for therapeutic decisions based on histological assessment,the reproducibility of Sydney system is important.The study was designed ... AIM:Because the presence or absence of H pylori infection has important implications for therapeutic decisions based on histological assessment,the reproducibility of Sydney system is important.The study was designed to test the reproducibility of features of Helicobacter pylori gastritis, using the updated Sydney classification. METHODS:Gastric biopsies of 40 randomly selected cases of H pylori gastritis were scored semiquantitatively by three pathologists.Variables analysed induded chronic inflammation, inflammatory activity,atrophy,intestinal metaplasia,H pylori, surface epithelial damage.κ values below 0.5 represented poor,those between 0.5 and 0.75 good and values over 0.75 excellent interobserver agreement. RESULTS:The best interobserver agreement(κ=0.62)was present for intestinal metaplasia.The agreement was the poorest for evaluating atrophy(κ=0.31). CONCLUSION:Although the results of this study were in accordance with some previous studies,an excellent agreement could not be reached for any features of H pylori gastritis.This low degree of concordance is assumed to be due to the personal evaluation differences in grading the features,the lack of standardized diagnostic criteria,and the ignorance to reach a consensus about the methods to be used in grading the features of H pylori gastritis before initiating the study. 展开更多
关键词 Helicobacter pylori ADULT Aged BIOPSY numerical data FEMALE GASTRITIS Helicobacter Infections Humans Male Middle Aged Observer Variation Pyloric Antrum random allocation
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Metabolic Changes in Rats with Photochemically Induced Cerebral Infarction and the Effects of Batroxobin:A Study by Magnetic Resonance Imaging,~1H-and ^(31)p-Magnetic Resonance Spectroscopy 被引量:6
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作者 管兴志 吴卫平 +6 位作者 匡培根 匡培梓 高杨 管林初 李丽云 毛希安 刘买利 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第1期59-67,共9页
Metabolic changes in rats with photochemically induced cerebral infarction and the effects of batroxobin were investigated 1, 3, 5 and 7 days after infarction by means of magnetic resonance imaging (MRI), 1H- and 31P-... Metabolic changes in rats with photochemically induced cerebral infarction and the effects of batroxobin were investigated 1, 3, 5 and 7 days after infarction by means of magnetic resonance imaging (MRI), 1H- and 31P-magnetic resonance spectroscopy (MRS). A region of T2 hyperintensity was observed in left temporal neocortex in infarction group and batroxobin group 1, 3, 5 and 7 days after infarction. The volume of the region gradually decreased from 1 day to 7 days after infarction. The ratio of NAA/Cho + Cr in the region of T2 hyperintensity in the infarction group was significantly lower than that in the corresponding region in the sham-operated group 3, 5 and 7 days after infarction respectively (P 展开更多
关键词 Animals Aspartic Acid BATROXOBIN Cerebral Infarction Magnetic Resonance Imaging Male PHOTOCHEMISTRY Photosensitizing Agents random allocation RATS Rats Sprague-Dawley Rose Bengal
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INHIBITORY EFFECT OF TRIMETAZIDINE ON CARDIAC MYOCYTE APOPTOSIS IN RABBIT MODEL OF ISCHEMIA-REPERFUSION 被引量:6
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作者 Rasheed AL-ghazali 《Chinese Medical Sciences Journal》 CAS CSCD 2004年第4期242-242,共1页
关键词 Animals APOPTOSIS Male MALONDIALDEHYDE Myocardial Ischemia Myocardial Reperfusion Injury Myocytes Cardiac Protective Agents Rabbits random allocation Research Support Non-U.S. Gov't Superoxide Dismutase TRIMETAZIDINE
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GAP-43 Expression and Pathological Changes of Temporal Infarction in R.ats and Effects of Batroxobin 被引量:4
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作者 吴卫平 管兴志 +1 位作者 匡培根 张小澍 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第1期42-46,共5页
To study the changes of the expression of growth-associated protein-43 (GAP-43) and pathology in temporal infarction of rats photochemically induced and the effects of batroxobin. METHODS: Immunohistochemical techniqu... To study the changes of the expression of growth-associated protein-43 (GAP-43) and pathology in temporal infarction of rats photochemically induced and the effects of batroxobin. METHODS: Immunohistochemical technique and hematoxylin-eosin stain was used to show the changes of the expression of GAP-43 and pathology. RESULTS: In infarction group, GAP-43 expression was markedly increased on the infarction and surrounding tissues at 24 h cerebral infarction. The expression reached peak level at 72 h after cerebral infarction and was decreased at 7 d after cerebral infarction. However, in batroxobin-treated group, GAP-43 expression was increased and the pathological changes were much slight as compared with infarction group. CONCLUSION: The expression of GAP-43 increases in infarction of temporal neocortex and batroxobin promotes the expression of GAP-43 and ameliorates the pathological changes in infarction of temporal neocortex. 展开更多
关键词 Animals BATROXOBIN Brain Infarction Fibrinolytic Agents GAP-43 Protein Male NEOCORTEX random allocation RATS Rats Wistar Temporal Lobe
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Effect of Batroxobin on Expression of Neural Cell Adhesion Molecule in Temporal Infarction Rats and Spatial Learning and Memory Disorder 被引量:4
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作者 吴卫平 管兴志 +6 位作者 匡培根 姜树军 扬炯炯 隋南 AlbertChen 匡培梓 张小澍 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第4期294-298,共5页
The effect of Batroxobin expression of neural cell adhesion molecule (NCAM) in left temporal ischemic rats with spatial memory disorder was investigated by means of Morri's water maze and immunohistochemical metho... The effect of Batroxobin expression of neural cell adhesion molecule (NCAM) in left temporal ischemic rats with spatial memory disorder was investigated by means of Morri's water maze and immunohistochemical methods. The results showed that the mean reaction time and distance of temporal ischemic rats for searching a goal were significantly longer than those of sham-operated rats and at the same time NCAM expression of left temporal ischemic region was significantly increased. However, the mean reaction time and distance of Batroxobin-treated rats were shorter and they used normal strategies more often and earlier than those of ischemic rats. The number of NCAM immune reactive cells of Batroxobin-treated rats was more than that of ischemic group. In conclusion, Batroxobin can improve spatial memory disorder of temporal ischemic rats and the regulation of the expression of NCAM is probably related to the neuroprotective mechanism. 展开更多
关键词 Animals BATROXOBIN Cell Adhesion Molecules Neuronal Cerebral Infarction Male Maze Learning Memory Disorders Neuroprotective Agents random allocation RATS Rats Wistar Temporal Lobe
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Effect of Batroxobin on Neuronal Apoptosis During Focal Cerebral Ischemia and Reperfusion in Rats 被引量:3
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作者 吴卫平 匡培根 李振洲 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第2期136-140,共5页
We have found that Batroxobin plays a protective role in ischemic brain injury, which attracted us to investigate the effect of Batroxobin on apoptosis of neurons during cerebral ischemia and reperfusion. The apoptoti... We have found that Batroxobin plays a protective role in ischemic brain injury, which attracted us to investigate the effect of Batroxobin on apoptosis of neurons during cerebral ischemia and reperfusion. The apoptotic cells in ischemic rat brains at different reperfusion intervals were tested with method of TdT-mediated dUTP-DIG nick end labeling (TUNEL) and the effect of Batroxobin on the apoptosis of neurons was studied in left middle cerebral artery (LMCA) occlusion and reperfusion in rat models (n = 18). The results showed that few scattered apoptosis cells were observed in right cerebral hemispheres after LMCA occlusion and reperfusion, and that a lot of apoptosis cells were found in left ischemic cortex and caudoputamen at 12 h reperfusion, and they reached peak at 24 h-48 h reperfusion. However, in the rats pretreated with Batroxobin, the number of apoptosis cells in left cerebral cortex and caudoputamen reduced significantly and the neuronal damage was much milder at 24 h reperfusion than that of saline-treated rats. The results indicate that administration of Batroxobin may reduce the apoptosis of neurons induced by cerebral ischemia and reperfusion and afford significant cerebroprotection in the model of focal cerebral ischemia and reperfusion. 展开更多
关键词 ANIMALS Apoptosis BATROXOBIN Brain Ischemia Male NEURONS Neuroprotective Agents random allocation RATS Rats Sprague-Dawley Reperfusion Injury
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Effects of Batroxobin on Spatial Learning and Memory Disorder of Rats with Temporal Ischemia and the Expression of HSP32 and HSP70 被引量:3
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作者 吴卫平 匡培根 +5 位作者 姜树军 张小澍 杨炯炯 隋南 Albert Chen 匡培梓 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第4期297-301,共5页
  The effect of Batroxobin on spatial memory disorder of left temporal ischemic rats and the expression of HSP32 and HSP70 were investigated with Morri`s water maze and immunohistochemistry methods. The results show...   The effect of Batroxobin on spatial memory disorder of left temporal ischemic rats and the expression of HSP32 and HSP70 were investigated with Morri`s water maze and immunohistochemistry methods. The results showed that the mean reaction time and distance of temporal ischemic rats in searching a goal were significantly longer than those of the sham-operated rats and at the same time HSP32 and HSP70 expression of left temporal ischemic region in rats was significantly increased as compared with the sham-operated rats. However, the mean reaction time and distance of the Batroxobin-treated rats were shorter and they used normal strategies more often and earlier than those of ischemic rats. The number of HSP32 and HSP70 immune reactive cells of Batroxobin-treated rats was also less than that of the ischemic group. In conclusion, Batroxobin can improve spatial memory disorder of temporal ischemic rats; and the down-regulation of the expression of HSP32 and HSP70 is probably related to the attenuation of ischemic injury. 展开更多
关键词 OXYGENASES Animals BATROXOBIN Brain Ischemia DOWN-REGULATION HSP70 Heat-Shock Proteins Heat-Shock Proteins Heme Oxygenase (Decyclizing) Learning Disorders Male Maze Learning Memory Disorders random allocation RATS Rats Wistar Snake Venoms Spatial Behavior Temporal Lobe
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Effects of Acupuncture on Monoamine Neurotransmitters in Raphe Nuclei in Obese Rats 被引量:2
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作者 魏群利 刘志诚 王友京 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第2期147-150,共4页
Effects of acupuncture on the levels of neurotransmitters in the raphe nuclei were investigated in obeserats.It was found that the levels of tryptophan (Trp) and 5-hydroxyindoleacetic acid (5-HIAA) wereincreased,and 5... Effects of acupuncture on the levels of neurotransmitters in the raphe nuclei were investigated in obeserats.It was found that the levels of tryptophan (Trp) and 5-hydroxyindoleacetic acid (5-HIAA) wereincreased,and 5-hydroxytryptamine (5-HT) level and 5-HT/5-HIAA ratio decreased in the raphe nucleiof the obese group as compared with the normal group;and that acupuncture could produce weightreduction,increase the 5-HT level and 5-HT/5-HIAA ratio,and decrease the contents of Trp and5-HIAA,but did not change the levels of dopamine (DA) and noradrenaline (NA).It is indicated thatbenign regulative action of acupuncture on 5-HT and its metabolism in the raphe nuclei is possibly oneof the factors for reducing weight by acupuncture. 展开更多
关键词 ACUPUNCTURE Animals Biogenic Monoamines Male NOREPINEPHRINE Obesity random allocation Raphe Nuclei RATS Rats Sprague-Dawley SEROTONIN TRYPTOPHAN Weight Loss
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The Regulatory Action of Radix Astragali on M-Cholinergic Receptor of the Brain of Senile Rats 被引量:2
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作者 石瑞如 何路明 +4 位作者 胡雅儿 易宁育 翁世艾 曹永舒 刘煜 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第3期232-235,共4页
The changes in density of M-cholinergic receptors in different areas of senile rats and the regulatory action of Huang Qi ([symbol: see text] Radix Astragali, a drug for warming yang and replenishing qi) were observed... The changes in density of M-cholinergic receptors in different areas of senile rats and the regulatory action of Huang Qi ([symbol: see text] Radix Astragali, a drug for warming yang and replenishing qi) were observed by autoradiography. The results showed that the gray scale displayed in brain sections was clear and mainly distributed in the cortex, hippocampus and striate body, while that due to nonspecific combination was negligible. The gray scale in the cortex, hippocampus and striate body of the experimental group was markedly lower than that in the young control rats, decreased respectively by 24.87%, 14.12% and 12.76% (all P 展开更多
关键词 Astragalus Plant Drugs Chinese Herbal Aging Animals AUTORADIOGRAPHY BRAIN Corpus Striatum Hippocampus Male random allocation RATS Rats Sprague-Dawley Receptors Muscarinic
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Effect of Acupuncture on Free Radicals in Rats with Early Experimental Spinal Cord Injury 被引量:2
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作者 吴永刚 孙忠人 +3 位作者 李志刚 赵永厚 孙申田 王友京 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第1期51-54,共4页
Effect of acupuncture on free radicals after spinal cord injury was observed in rats with experimental spinal cord injury (SCI). Results indicated that within 24 hours after SCI malondialdehyde (MDA) increased progres... Effect of acupuncture on free radicals after spinal cord injury was observed in rats with experimental spinal cord injury (SCI). Results indicated that within 24 hours after SCI malondialdehyde (MDA) increased progressively, 2 hours after SCI it reached the peak; and the superoxide dismutase (SOD) activity decreased significantly at the same hours, the decrease being the most marked 2-6 hours after SCI. The MDA content in the acupuncture group was significantly lower (P 展开更多
关键词 ELECTROACUPUNCTURE ANIMALS Female Free Radicals Male MALONDIALDEHYDE random allocation RATS Rats Wistar Spinal Cord Injuries Superoxide Dismutase
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EFFECTS OF ACUPUNCTURE ON THE PITUITARYTHYROID AXIS IN RABBITS WITH FRACTURE 被引量:1
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作者 沈梅红 祁晓华 +3 位作者 黄晔 吕越 蔡文辉 王友京 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1999年第4期300-303,共4页
PURPOSE: To observe the effects of acupuncture on the pituitary-thyroid axis in rabbits with fracture. METHOD: 36 male rabbits with a 3-mm width experimental defect in the middle segment of the left radius were random... PURPOSE: To observe the effects of acupuncture on the pituitary-thyroid axis in rabbits with fracture. METHOD: 36 male rabbits with a 3-mm width experimental defect in the middle segment of the left radius were randomly divided into the treatment group and control group, and the changes in serum T3, T4 and TSH contents in different weeks were investigated. RESULTS: Serum T3, T4 and TSH contents in the treatment group all were higher than those in the control group, with statistically significant differences in the contents of T4 and TSH in the second week and T3 content in the fourth week (P 展开更多
关键词 ELECTROACUPUNCTURE Animals Hypothalamo-Hypophyseal System Male RABBITS Radius Fractures random allocation Thyroid Gland THYROTROPIN THYROXINE TRIIODOTHYRONINE
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The Effects of Electroacupuncture at the Heart Meridian on Myocardial Contractile Function in Rabbits with Myocardial Ischemia
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作者 Fang Zhibin(方志斌) +3 位作者 Zhou Yiping(周逸平) Wang Yuelan(王月兰) 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第1期47-50,共4页
  Acute myocardial ischemia was induced by intravenous injection of pituitrin, and electroacupuncture (EA) was applied at the Heart and Lung Meridians (HM and LM), 3 points on each meridian. The changes in the left ...   Acute myocardial ischemia was induced by intravenous injection of pituitrin, and electroacupuncture (EA) was applied at the Heart and Lung Meridians (HM and LM), 3 points on each meridian. The changes in the left intraventricular pressure (LVP), the maximum rise rate of intraventricular pressure (LVP dp/dtmax), the area of cardiac force loop (ACFL), and the maximum shortening velocity of myocardial contractile element (Vmax) were observed. As a result, there were significant differences in the improvement of LVP, LVP dp/dtmax, ACFL and Vmax between EA at HM and LM. The regulatory action of EA at HM on the myocardial contractile function was significantly better than that of EA at LM, indicating that HM has a close relationship with the myocardial contractile function.…… 展开更多
关键词 ELECTROACUPUNCTURE ANIMALS Female Male MERIDIANS Myocardial Contraction Myocardial Ischemia Pituitary Hormones Posterior RABBITS random allocation Ventricular Function Left
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