The flavonoids is a kind of complex compound and quercetin is a main composition in rape pollen.Taking quercetin as a sample and using separation technology and high performance liquid chromatography,chromatography fi...The flavonoids is a kind of complex compound and quercetin is a main composition in rape pollen.Taking quercetin as a sample and using separation technology and high performance liquid chromatography,chromatography fingerprint technique of Chinese medicine is introduced in food field to construct chromatography fingerprint of rape pollen,which can be used for medicinal use and edible use.The method will become a beneficial supplement for quality control method to ensure the safety and effectiveness of products.展开更多
Four peptide components RP1,RP2,RP3Ⅰ and RP3Ⅱ were purified from the water—ex- tract of rape(Brassica campestris L.)pollen.The primary sequence of RP3I,with 12 amino acid residues,has been determined by Edman degra...Four peptide components RP1,RP2,RP3Ⅰ and RP3Ⅱ were purified from the water—ex- tract of rape(Brassica campestris L.)pollen.The primary sequence of RP3I,with 12 amino acid residues,has been determined by Edman degradation—N—terminal dansylation.The immunopro- motive activities of the initially separated sample and RP3I have been also observed in vitro.展开更多
A dodecapeptide extracted from rape pollen was synthesized using solid—phase method,its conforma- tions in different states were studied by FT—IR,CD,and its physiological activities were determined.Seven segments an...A dodecapeptide extracted from rape pollen was synthesized using solid—phase method,its conforma- tions in different states were studied by FT—IR,CD,and its physiological activities were determined.Seven segments and five analogs were also synthesized to elucidate the structure—function relation.展开更多
Background Flavonoids from fruits, vegetables and plants have been widely studied on their improving lipidemia, anti-inflammation, anti-platelet aggregation and anti-oxidative activities. However, t know if flavonoids...Background Flavonoids from fruits, vegetables and plants have been widely studied on their improving lipidemia, anti-inflammation, anti-platelet aggregation and anti-oxidative activities. However, t know if flavonoids from rape bee pollen have the same effects in patients with dyslipidemia (DL), effects of we don' type 2 diabetes mellitus(T2DM), and cerebral infarction(CI). Methods The study involved with patients selected and divided into 4 groups, 30 cases of DL, of T2DM, of CI and health control (HC) for each. Forty mg flavonoids from rape bee pollen administrated orally twice a day for two months. Blood sugar (BG), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), low white blood-cell counts (WBC), platelet counts (PLT), high-sens malondialdehyde (MDA) were analyzed in four groups before and after density lipoprotein-cholesterol (LDL-C), itivity C-reactive protein (hsCRP) and taking flavonoids for two months. Results (1) Basic levels of TC, BG, WBC, PLT and hsCRP in groups of T2DM, CI, and TG and MDA in groups of DL, PLT, T2DM and CI were significantly higher than those in HC (P 〈 0.05-0.001). (2) The levels of hsCRP and MDA were significantly decreased, flavonoids for two months (P 〈 0.05-0.001) in group of while HDL-C was remarkably increased DL, T2MD, and CL These indexes were not the group of HC after taking flavonoids (P 〉 0.05). Conclusions The results could indieat disturbance, inflammation, and high oxidative stress in patients with dyslipidemisa, type 2 diabet TG, WBC, after taking different in e metabolic es mellitus, and cerebral infarction. The flavonoids from rape bee pollen may have effects of antioxidant activity, improving lipids, and anti-inflammation on these patients.展开更多
文摘The flavonoids is a kind of complex compound and quercetin is a main composition in rape pollen.Taking quercetin as a sample and using separation technology and high performance liquid chromatography,chromatography fingerprint technique of Chinese medicine is introduced in food field to construct chromatography fingerprint of rape pollen,which can be used for medicinal use and edible use.The method will become a beneficial supplement for quality control method to ensure the safety and effectiveness of products.
文摘Four peptide components RP1,RP2,RP3Ⅰ and RP3Ⅱ were purified from the water—ex- tract of rape(Brassica campestris L.)pollen.The primary sequence of RP3I,with 12 amino acid residues,has been determined by Edman degradation—N—terminal dansylation.The immunopro- motive activities of the initially separated sample and RP3I have been also observed in vitro.
文摘A dodecapeptide extracted from rape pollen was synthesized using solid—phase method,its conforma- tions in different states were studied by FT—IR,CD,and its physiological activities were determined.Seven segments and five analogs were also synthesized to elucidate the structure—function relation.
基金supported by The Capital Development Fund(2005-SF-Ⅱ-007)
文摘Background Flavonoids from fruits, vegetables and plants have been widely studied on their improving lipidemia, anti-inflammation, anti-platelet aggregation and anti-oxidative activities. However, t know if flavonoids from rape bee pollen have the same effects in patients with dyslipidemia (DL), effects of we don' type 2 diabetes mellitus(T2DM), and cerebral infarction(CI). Methods The study involved with patients selected and divided into 4 groups, 30 cases of DL, of T2DM, of CI and health control (HC) for each. Forty mg flavonoids from rape bee pollen administrated orally twice a day for two months. Blood sugar (BG), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), low white blood-cell counts (WBC), platelet counts (PLT), high-sens malondialdehyde (MDA) were analyzed in four groups before and after density lipoprotein-cholesterol (LDL-C), itivity C-reactive protein (hsCRP) and taking flavonoids for two months. Results (1) Basic levels of TC, BG, WBC, PLT and hsCRP in groups of T2DM, CI, and TG and MDA in groups of DL, PLT, T2DM and CI were significantly higher than those in HC (P 〈 0.05-0.001). (2) The levels of hsCRP and MDA were significantly decreased, flavonoids for two months (P 〈 0.05-0.001) in group of while HDL-C was remarkably increased DL, T2MD, and CL These indexes were not the group of HC after taking flavonoids (P 〉 0.05). Conclusions The results could indieat disturbance, inflammation, and high oxidative stress in patients with dyslipidemisa, type 2 diabet TG, WBC, after taking different in e metabolic es mellitus, and cerebral infarction. The flavonoids from rape bee pollen may have effects of antioxidant activity, improving lipids, and anti-inflammation on these patients.