Climate change which is mainly caused by carbon emissions is a global problem affecting the economic development and well-being of human society.Low-carbon agriculture is of particular significance in slowing down glo...Climate change which is mainly caused by carbon emissions is a global problem affecting the economic development and well-being of human society.Low-carbon agriculture is of particular significance in slowing down global warming and reaching the goal of“carbon peak and carbon neutrality”.Therefore,taking straw incorporation as an example,this paper aims to investigate the impact of risk preferences on farmers’low-carbon agricultural technology(LCAT)adoption.Based on a two-phase micro-survey data of 1038 rice farmers in Jiangsu,Jiangxi,and Hunan provinces,this paper uses experimental economics methods to measure farmers’risk aversion and loss aversion to obtain the real risk preferences information of the farmers.We also explore the data to examine the actual LCAT adoption behavior of farmers.The results revealed that both risk aversion and loss aversion significantly inhibit farmers’LCAT adoption:more risk-averse or more loss-averse farmers are less likely to adopt LCAT.It is further found that crop insurance,farm scale and governmental regulations can alleviate the negative impact of risk aversion and loss aversion on farmers’LCAT adoption.Therefore,we propose that local governments need to promote low-carbon agricultural development by propagating the benefits of LCAT,extending crop insurance,promoting appropriate scale operations,and strengthening governmental regulations to promote farmers’LCAT adoption.展开更多
This paper examined consumers’experiences in and preferences for plant-based meat(PBM)food and their respective correlates,based on data from an online survey of 579 consumers in four major cities in China in early 2...This paper examined consumers’experiences in and preferences for plant-based meat(PBM)food and their respective correlates,based on data from an online survey of 579 consumers in four major cities in China in early 2021.We first described consumers’experiences in consuming and purchasing PBM food and their correlates,and then analyzed consumer preferences using hypothetical choice experiment.The experiment offered consumers various options to purchase burgers made from PBM or animal-based meat(ABM),combined with different countries of origin(COO),taste labels,and prices.Our data showed that respondents hold overall positive attitudes toward PBM food;85 and 82%of respondents reported experience in eating and purchasing PBM food,respectively.More than half of them ate PBM food because they wanted to try new food(58%),or were interested in healthy food(56%).Income,religion,and dietary restrictions were significantly correlated with consumers’experiences in PBM food consumption.Results from the Random Parameter Logit Model based on the hypothetical choice experiment data showed that 79%of respondents chose PBM burgers and were willing to pay an average of 88 CNY for a PBM burger.We also found that 99.8 and 83%of respondents are willing to buy burgers made in China and those with a taste label,with a willingness to pay(WTP)of 208 and 120 CNY,respectively.The heterogeneity test revealed that females and those with at least a bachelor’s degree,higher income,religious beliefs,and dietary restrictions are more likely to buy PBM burgers than their counterparts.展开更多
Since the introduction of antiretroviral therapy, the life expectancy of people living with human immunodeficiency virus (PLWH) has extended. This extension has led to an increase in the aging population in Japan and ...Since the introduction of antiretroviral therapy, the life expectancy of people living with human immunodeficiency virus (PLWH) has extended. This extension has led to an increase in the aging population in Japan and globally. Providing appropriate long-term care (LTC) for PLWH has thus become increasingly critical. Our study aimed to describe LTC setting preferences and related factors among middle-aged and older Japanese people living with HIV. A cross-sectional survey was conducted at two hospitals in Tokyo. One hundred seventy-five outpatients aged 40 years and above participated in this study. Participants completed an anonymous self-administered questionnaire to assess where they wanted to live once they could no longer care for themselves. Approximately 52.0% preferred a designated facility for older adults or LTC, while 30.3% preferred their home or living with family, a partner, or a friend (“familiar housing”). Bivariate analyses revealed that LTC setting preference was significantly associated with marital status, whether or not the participant had at least one child, and household composition. Furthermore, logistic regression analysis revealed that participants living with non-kin were less likely to prefer living in designated housing facilities for older adults or LTC (adjusted odds ratio = 0.17, 95% confidence interval: 0.05 - 0.63). The study findings suggest that family make-up and composition of cohabiters are critical indicators for LTC setting preference in this population. These findings can be the foundation for future care planning and delivery to meet the unique LTC needs and expectations of the aging population with HIV in Japan and similar global settings.展开更多
BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling...BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling,and purulent perianal discharge,and METHODS This cross-sectional observational study was conducted in patients with CD aged 21-90 years via a web-enabled questionnaire in seven countries(April-August 2021).Patients were recruited into three cohorts:Cohort 1 included patients without perianal fistulas;cohort 2 included patients with perianal fistulas without fistula-related surgery;and cohort 3 included patients with perianal fistulas and fistula-related surgery.Validated patient-reported outcome measures were used to assess quality of life.Drivers of treatment preferences were measured using a discrete choice experiment(DCE).RESULTS In total,929 patients were recruited(cohort 1,n=620;cohort 2,n=174;cohort 3,n=135).Short Inflammatory Bowel Disease Questionnaire scores were worse for patients with CPF(cohorts 2 and 3)than for those with CD without CPF(cohort 1):Mean score 3.8 and 3.7 vs 4.1,respectively,(P<0.001).Similarly,mean Revised FI and FI Quality of Life scores were worse for patients with CPF than for those with CD without CPF.Quality of Life with Anal Fistula scores were similar in patients with CPF with or without CPF-related surgery(cohorts 2 and 3):Mean score 41 and 42,respectively.In the DCE,postoperative discomfort and fistula healing rate were the most important treatment attributes influencing treatment choice:Mean relative importance 35.7 and 24.7,respectively.CONCLUSION The burden of illness in CD is significantly higher for patients with CPF and patients rate lower postoperative discomfort and higher healing rates as the most desirable treatment attributes.展开更多
Soymilk is one of the most available beverages, an alternative to dairy milk and is recognized for its nutritional value. The nutritional quality, the presence of anti-nutritional factors, isoflavones and sensory acce...Soymilk is one of the most available beverages, an alternative to dairy milk and is recognized for its nutritional value. The nutritional quality, the presence of anti-nutritional factors, isoflavones and sensory acceptability of soymilk depended on the soybean variety as well as the processing conditions. The soymilks from conventional and specialty Brazilian soybean cultivars were compared regarding the composition and consumer acceptance. There were significant differences on the protein, oil, sugars, isoflavones, presence of anti-nutritional factors (phytate and trypsin inhibitor activity) and NSI (nitrogen solubility index) among cultivars and soymilks and for sensory acceptance of soymilks. The preference mapping and cluster analysis identified three different segments of consumers. The soymilk from the conventional cultivar BRS284 achieved higher and similar acceptance score for the three consumer’s segments while the lipoxygenase free cultivars (BRS213 and BRS257) and specialty cultivar BRS216 showed higher score for two segments of consumers. The sensory evaluation of soymilk from different soybean cultivars could improve consumer uptake.展开更多
Background:The midwife plays a critical role in health counselling and education,not just for women but also for their families and communities.At the current time,with the growth of the midwifery workforce globally,t...Background:The midwife plays a critical role in health counselling and education,not just for women but also for their families and communities.At the current time,with the growth of the midwifery workforce globally,there is still a lack of understanding regarding the full scope and role of the midwife.Aim:To evaluate the current situation of knowledge of midwives’role among women in Makkah.In addition,this study identifies the effect of women’s knowledge on their preferences for receiving maternity care from health professionals.Methods:This study employed a descriptive quantitative cross-sectional method.The total resultant sample size(N)equalled 379 global respondents,of which 306,with a response rate=of 80.73%completed the entire survey as requested.An electronic questionnaire in the Arabic language was used in this study.Results:Results revealed that most women had incorrect knowledge regarding three aspects of the midwives’roles during pregnancy 53.9%,labour 52.8%and childbirth 61.9%.Also,results presented that most women preferred obstetricians to follow up on an uncomplicated pregnancy,labour,childbirth,and maternity care 69.6%,53.9%,64.7%and 46.1%,respectively.The study found that the women’s knowledge about midwives’roles affects their preferences for healthcare professionals in receiving maternity care(P<0.05).Conclusion:Responses showed that most participants had no experience and had negative views about midwives’roles.Thus,it would affect their health professionals’preferences for receiving maternity care.Therefore,midwifery services and maternity care professionals should prioritize educating women about midwives’competencies in maternity care.展开更多
A deep learning access controlmodel based on user preferences is proposed to address the issue of personal privacy leakage in social networks.Firstly,socialusers andsocialdata entities are extractedfromthe social netw...A deep learning access controlmodel based on user preferences is proposed to address the issue of personal privacy leakage in social networks.Firstly,socialusers andsocialdata entities are extractedfromthe social networkandused to construct homogeneous and heterogeneous graphs.Secondly,a graph neural networkmodel is designed based on user daily social behavior and daily social data to simulate the dissemination and changes of user social preferences and user personal preferences in the social network.Then,high-order neighbor nodes,hidden neighbor nodes,displayed neighbor nodes,and social data nodes are used to update user nodes to expand the depth and breadth of user preferences.Finally,a multi-layer attention network is used to classify user nodes in the homogeneous graph into two classes:allow access and deny access.The fine-grained access control problem in social networks is transformed into a node classification problem in a graph neural network.The model is validated using a dataset and compared with other methods without losing generality.The model improved accuracy by 2.18%compared to the baseline method GraphSAGE,and improved F1 score by 1.45%compared to the baseline method,verifying the effectiveness of the model.展开更多
Introduction: Females with sickle cell disease (SCD), despite having a delayed pubertal development, are subject to many worries relating to their abilities to conceive, their capacity to maintain a maternofetal-risk-...Introduction: Females with sickle cell disease (SCD), despite having a delayed pubertal development, are subject to many worries relating to their abilities to conceive, their capacity to maintain a maternofetal-risk-free pregnancy till term and give birth to healthy children without sickle cell disease. Knowing that unplanned pregnancies are more likely to increase maternofetal morbidity and mortality, we sought out to explore the pregnancy preferences in female patients with sickle cell disease to promote healthy conception and childbirth in this vulnerable population. Methodology: We conducted a cross-sectional study involving female patients of child-bearing age with sickle cell disease followed at Laquintinie Hospital Douala or who were members of a local sickle cell association. Pregnancy preferences were determined using the Desire to Avoid Pregnancy (DAP) scale. Factors associated with pregnancy preferences were determined using multivariable linear regression model. Threshold for significance was set at p Results: Seventy-seven patients were included with a mean age of 24.71 ± 5.53 years. Forty patients (51.95%) had one sexual partner and thirteen women (32.5%) used contraceptive methods. Most patients (46.0%) responded “Strongly Agree” or “Agree” to the statement “it would be a good thing for me if I became pregnant in the next 3 months”. The mean DAP score was 1.63 ± 0.91 [1.28 ± 0.82 in those who had a sexual partner and 1.99 ± 0.86 in those who had no sexual partner]. Factors that were positively associated with DAP score were students (b = 0.32, 95% CI [0.21, 0.95], p = 0.003), monthly income ≥ 100,000 FCFA (b = 0.24, 95% CI [0.07, 0.81], p = 0.022), and not having a sexual partner (b = 0.26, 95% CI [0.11, 0.85], p = 0.012). Conclusion: Most female patients with SCD have a low desire to avoid pregnancy. This is especially true for patients who are not students, have a partner and have a low monthly income.展开更多
Many different factors,such as species traits,socio-economic factors,geographical and environmental factors,can lead to specimen collection preference.This study aims to determine whether grassland specimen collection...Many different factors,such as species traits,socio-economic factors,geographical and environmental factors,can lead to specimen collection preference.This study aims to determine whether grassland specimen collection in China is preferred by species traits(i.e.,plant height,flowering and fruiting period),environmental range(i.e.,the temperature and precipitation range)and geographical range(i.e.,distribution range and altitudinal range).Ordinary least squares models and phylogenetic generalized linear mixed models were used to analyze the relationships between specimen number and the explanatory variables.Random Forest models were then used to find the most parsimonious multivariate model.The results showed that interannual variation in specimen number between 1900 and 2020 was considerable.Specimen number of these species in southeast China was notably lower than that in northwest China.Environmental range and geographical range of species had significant positive correlations with specimen number.In addition,there were relatively weak but significant associations between specimen number and species trait(i.e.,plant height and flowering and fruiting period).Random Forest models indicated that distribution range was the most important variable,followed by flowering and fruiting period,and altitudinal range.These findings suggest that future floristic surveys should pay more attention to species with small geographical range,narrow environmental range,short plant height,and short flowering and fruiting period.The correction of specimen collection preference will also make the results of species distribution model,species evolution and other works based on specimen data more accurate.展开更多
BACKGROUND Primary thumb carpometacarpal(CMC)osteoarthritis is one of the most common conditions encountered by hand surgeons.Of the vast number of operations that have been proposed,none have demonstrated results sig...BACKGROUND Primary thumb carpometacarpal(CMC)osteoarthritis is one of the most common conditions encountered by hand surgeons.Of the vast number of operations that have been proposed,none have demonstrated results significantly superior to trapeziectomy alone.AIM The purpose of our study was to determine why surgeons opt for their technique in treating CMC arthritis.METHODS A cross-sectional survey of active members of the American Society for Surgery of the Hand was conducted to evaluate the reasons behind their preferred technique in the treatment of isolated thumb CMC arthritis.Surgeons were contacted by email once and provided with a link to a de-identified survey consisting of 5 treatment questions and 5 demographic questions.RESULTS Of 950 responses were received.40.5%of surgeons preferred trapeziectomy+ligament reconstruction tendon interposition(LRTI),followed by trapeziectomy+suspensionplasty(28.2%),suture button suspension(5.9%),trapeziectomy alone(4.6%),prosthetic arthroplasty(3.2%),arthrodesis(1.1%),and other(6.6%).Proponents of trapeziectomy+LRTI cited familiarity(73.2%),exposure during fellowship(48.8%)and less proximal migration(60%)to be the main reasons affecting their decision.Surgeons who preferred trapeziectomy+suspensionplasty most reported simplicity(74.9%),fewer complications(45.3%),less proximal migration(43.8%),and avoidance of autogenous tissue harvest(42.7%).Advocates of suture button suspension cited avoidance of autogenous tissue harvest(80.4%),shorter immobilization(76.8%),and quicker recovery(73.2%)with their technique.Advocates of trapeziectomy alone cited simplicity(97.7%),fewer complications(86.4%),and avoidance of autogenous tissue harvest(59.1%).In their comments,45%of surgeons choosing trapeziectomy alone cited evidence as an additional rationale.Advocates of prosthetic arthroplasty cited improved pinch strength(83.3%)and improved range of motion(63.3%),while those preferring arthrodesis cited better pinch strength(90%)and frequently in their comments,durability.Of the surgeons who preferred a technique other than LRTI,41.8%reported they had tried LRTI in the past,citing complexity of the procedure,flexor carpi radialis harvest,and longer operative time as reasons for moving on.CONCLUSION Our study provides an update on current treatment trends and offers new insight into the reasons behind surgeons'decision making in the management of thumb carpometacarpal osteoarthritis.Despite strong Level 1 evidence supporting the use of trapeziectomy alone,our findings demonstrate that most surgeons continue to supplement trapeziectomy with other techniques such as LRTI or suspensionplasty.Several factors including familiarity,personal experience(Level 4 evidence),and comfort may be more influential than Level 1 evidence in determining the techniques in a surgeon's armamentarium.Further prospective studies are needed to determine the optimal technique for surgical management of Eaton stages II-IV CMC arthritis and how these studies will affect surgeons’choice.展开更多
Monolithic textured perovskite/silicon tandem solar cells(TSCs)are expected to achieve maximum light capture at the lowest cost,potentially exhibiting the best power conversion efficiency.However,it is challenging to ...Monolithic textured perovskite/silicon tandem solar cells(TSCs)are expected to achieve maximum light capture at the lowest cost,potentially exhibiting the best power conversion efficiency.However,it is challenging to fabricate high-quality perovskite films and preferred crystal orientation on commercially textured silicon substrates with micrometersize pyramids.Here,we introduced a bulky organic molecule(4-fluorobenzylamine hydroiodide(F-PMAI))as a perovskite additive.It is found that F-PMAI can retard the crystallization process of perovskite film through hydrogen bond interaction between F^(−)and FA^(+)and reduce(111)facet surface energy due to enhanced adsorption energy of F-PMAI on the(111)facet.Besides,the bulky molecular is extruded to the bottom and top of perovskite film after crystal growth,which can passivate interface defects through strong interaction between F-PMA+and undercoordinated Pb^(2+)/I^(−).As a result,the additive facilitates the formation of large perovskite grains and(111)preferred orientation with a reduced trap-state density,thereby promoting charge carrier transportation,and enhancing device performance and stability.The perovskite/silicon TSCs achieved a champion efficiency of 30.05%based on a silicon thin film tunneling junction.In addition,the devices exhibit excellent longterm thermal and light stability without encapsulation.This work provides an effective strategy for achieving efficient and stable TSCs.展开更多
Female grasshoppers can affect the fitness of their offspring through their selection of oviposition site. Knowledge of soil type on oviposition, and its effects on subsequent development can provide guidelines for ha...Female grasshoppers can affect the fitness of their offspring through their selection of oviposition site. Knowledge of soil type on oviposition, and its effects on subsequent development can provide guidelines for habitat manipulations that reduce the harmful effects of these pests on farmers fields. The influence of soil types on the oviposition site preference of variegated grasshopper (Zonocerus variegatus L.) reared some cassava (Manihot esculenta Crantz) varieties, was investigated in a cage trial carried out at the Bio factory laboratory, School of Agriculture and Food Sciences, Njala University, Sierra Leone during 2022/2023. The treatments comprised three soil types (Sandy, Loamy and Clay), each with three replications laid out in a randomized complete block design (RCBD) in wooden cages. Data were collected on the following development parameters including, Net reproductive growth ratio (R0), Generation time (Tc), Intrinsic rate of increase (rm), Finite rate of increase (), Doubling time (Dt), and overall survivorship. Findings revealed that, Z. variegatus L. preferred sandy soil in which, on average, most eggs were deposited (338, 6.62 4.40), followed by loamy soil, 286 (5.53 3.96), and then, clayey soil, 200 (3.91 3.85);though, the differences were not significant. This study established that Z. variegatus deposited more eggs in sandy soil > loamy soil > clayey soil, respectively;and subsequent survivorship of the immature unto mature adult insect, revealed a similar order. This indicates that the sandy soil is the most preferred substrate for oviposition and subsequent development into adult insects.展开更多
Background:Bitter taste receptors(Tas2rs)are generally considered to sense various bitter compounds to escape the intake of toxic substances.Bitter taste receptors have been found to widely express in extraoral tissue...Background:Bitter taste receptors(Tas2rs)are generally considered to sense various bitter compounds to escape the intake of toxic substances.Bitter taste receptors have been found to widely express in extraoral tissues and have important physiological functions outside the gustatory system in vivo.Methods:To investigate the physiological functions of the bitter taste receptor cluster Tas2r106/Tas2r104/Tas2r105/Tas2r114 in lingual and extraoral tissues,multiple Tas2rs mutant mice and Gnat3 were produced using CRISPR/Cas9 gene-editing technique.A mixture containing Cas9 and sgRNA mRNAs for Tas2rs and Gnat3 gene was microinjected into the cytoplasm of the zygotes.Then,T7EN1 assays and sequencing were used to screen genetic mutation at the target sites in founder mice.Quantitative real-time polymerase chain reaction(qRT-PCR)and immunostaining were used to study the expression level of taste signaling cascade and bitter taste receptor in taste buds.Perception to taste substance was also studied using twobottle preference tests.Results:We successfully produced several Tas2rs and Gnat3 mutant mice using the CRISPR/Cas9 technique.Immunostaining results showed that the expression of GNAT3 and PLCB2 was not altered in Tas2rs mutant mice.But qRT-PCR results revealed the changed expression profile of m Tas2rs gene in taste buds of these mutant mice.With two-bottle preference tests,these mutant mice eliminate responses to cycloheximide due to genetic mutation of Tas2r105.In addition,these mutant mice showed a loss of taste perception to quinine dihydrochloride,denatonium benzoate,and cucurbitacin B(CuB).Gnat3-mediated taste receptor and its signal pathway contribute to CuB perception.Conclusions:These findings implied that these mutant mice would be a valuable means to understand the biological functions of TAS2Rs in extraoral tissues and investigate bitter compound-induced responses mediated by these TAS2Rs in many extraoral tissues.展开更多
Case-based reasoning(CBR) is one of the best methods for generating an effective solution in an emergency. In recent years, some methods for generating emergency alternatives have been included in practical CBR applic...Case-based reasoning(CBR) is one of the best methods for generating an effective solution in an emergency. In recent years, some methods for generating emergency alternatives have been included in practical CBR applications, but there have been no in-depth studies of these processes. In this study,we propose a new method for dynamic case retrieval with subjective preferences and objective information, which considers the personal preferences of the decision makers and changes in the attributes of the emergency as the situation develops. First,we present a formula for calculating the case similarity and changing trends in the case considered, where similar cases are obtained. Next, we describe a method for measuring the overall assessment value with respect to similar historical cases, which is obtained by aggregating the case similarity, the utility case similarity, the first response time, and the implementation effect.The subjective preferences and objective information are also integrated in the decision-making process. Finally, we present a case study based on the emergency response to a fire in a highrise building, which illustrates the applicability and feasibility of the proposed method.展开更多
Many agricultural landscapes have been formed through the interaction and co-evolution of nature and people, and represent the living landscapes shaped over time through intensive and continuous human cultivation. Ter...Many agricultural landscapes have been formed through the interaction and co-evolution of nature and people, and represent the living landscapes shaped over time through intensive and continuous human cultivation. Terraced paddy fields are being re-evaluated to take into account the multiple functions they fill beyond only rice cultivation, particularly their contribution to the national biodiversity strategy of Japan. Since the 1990 s, terraced paddy fields have been considered a representative cultural landscape of Japan and, at the same time, multi-stakeholder conservation activities have been conducted throughout Japan to reverse the increasing abandonment of terraces. Shiroyone Senmaida is an outstanding cultural landscape and a major tourist attraction in Noto Peninsula, Ishikawa Prefecture, which was designated through an initiative by the Food and Agriculture Organization(FAO) as a Globally Important Agricultural Heritage Systems(GIAHS) pilot site in 2011. It is important to clarify tourist preference for terraced paddy field landscapes to contribute to future policy making toward improved agricultural landscape conservation. A key finding of this study is that tourists visiting toenjoy the agricultural landscape are also concerned on the sustainability of the farming methods and preferred to maintain the naturalness of the landscape. Respondents with higher educational levels and greater concern for the biological and traditional farming knowledge aspects of the rice terraces were also more inclined to favor sustainable farming practices. Tourists preferred to maintain the naturalness and rurality of the agricultural landscape, and indicated that construction of excessive tourist facilities would cause the landscape to deteriorate. It was suggested that the local community and surroundings, including rural settlements, hills, and forests, should also be conserved together with the scenic terrace.展开更多
This study examined public attitudes concerning the value of outdoor spaces which people use daily. Two successive analyses were performed based on data from common residents and college students in the city of Hangzh...This study examined public attitudes concerning the value of outdoor spaces which people use daily. Two successive analyses were performed based on data from common residents and college students in the city of Hangzhou, China. First, citizens registered various items constituting desirable values of residential outdoor spaces through a preliminary questionnaire. The result proposed three general attributes (functional, aesthetic and ecological) and ten specific qualities of residential outdoor spaces. An analytic hierarchy process (AHP) was applied to an interview survey in order to clarify the weights among these attributes and qualities. Second, principal factors were extracted from the ten specific qualities with principal component analysis (PCA) for both the common case and the campus case. In addition, the variations of respondents’ groups were classified with cluster analysis (CA) using the results of the PCA. The results of the AHP application found that the public prefers the functional attribute, rather than the aesthetic attribute. The latter is always viewed as the core value of open spaces in the eyes of architects and designers. Fur-thermore, comparisons of ten specific qualities showed that the public prefers the open spaces that can be utilized conveniently and easily for group activities, because such spaces keep an active lifestyle of neighborhood communication, which is also seen to protect human-regarding residential environments. Moreover, different groups of respondents diverge largely in terms of gender, age, behavior and preference.展开更多
Considering that the assumption of time consistency does not adequately reveal the mechanisms of exit decisions of venture capital(VC),this study proposes two kinds of time-inconsistent preferences(i.e.,time-flow inco...Considering that the assumption of time consistency does not adequately reveal the mechanisms of exit decisions of venture capital(VC),this study proposes two kinds of time-inconsistent preferences(i.e.,time-flow inconsistency and time-point incon-sistency)to advance research in this field.Time-flow inconsistency is in line with the previous time inconsistency literature,while time-point inconsistency is rooted in the VC fund’s finite lifespan.Based on the assumption about the strategies guiding future behaviors,we consider four types of venture capitalists:time-consistent,time-point-inconsistent,naïve,and sophisticated venture capitalists,of which the latter three are time-inconsistent.We derive and compare the exit thresholds of these four types of venture capitalists.The main results include:(1)time-inconsistent preferences acceler-ate the exits of venture capitalists;(2)the closer the VC funds expiry dates are,t`he more likely time-inconsistent venture capitalists are to accelerate their exits;and(3)future selves caused by time-flow inconsistency weaken the effect of time-point inconsist-ency.Our study provides a behavioral explanation for the empirical fact of young VCs’grandstanding.展开更多
Over the last decade, the popularity of Transportation Network Companies (TNCs) as a mode of travel has been increasing at a steady pace. This trend <span style="font-family:Verdana;">highlights the im...Over the last decade, the popularity of Transportation Network Companies (TNCs) as a mode of travel has been increasing at a steady pace. This trend <span style="font-family:Verdana;">highlights the importance of identifying the determinants that influence transportati</span><span style="font-family:Verdana;">on users to adopt TNCs as a preferred mode choice and the impacts of su</span><span style="font-family:Verdana;">ch preferences on their travel patterns and transportation network o</span><span style="font-family:Verdana;">peration. This paper reports on a recent study undertaken in Birmingham, AL aiming at understanding and documenting the factors that influence transportation users to select TNCs (such as Uber/Lyft) for completing typical day trips. In </span><span style="font-family:Verdana;">doing so, a travel diary questionnaire survey was developed in accordance with</span> <span style="font-family:Verdana;">the Institute of Transportation Engineers (ITE) Manual on Transportation Engineering Studies using the Qualtrics Research Core platform. The que</span><span style="font-family:Verdana;">stionnair</span><span style="font-family:Verdana;">e was used to survey over 450 transportation users in the Birmingham Metro area. The survey participants provided detailed trip information for a </span><span style="font-family:Verdana;">typical 24-hr day along with demographic data and travel preference informatio</span><span style="font-family:Verdana;">n. The survey responses provide high-resolution micro-level indicators </span><span style="font-family:Verdana;">of travel preferences and behaviors in a TNC-served area, which is a much-needed </span><span style="font-family:Verdana;">type of information for researchers and transportation planning agencies.</span>展开更多
We investigate the significance of extreme positive returns in the cross-sectional pricing of cryptocurrencies.Through portfolio-level analyses and weekly cross-sectional regressions on all cryptocurrencies in our sam...We investigate the significance of extreme positive returns in the cross-sectional pricing of cryptocurrencies.Through portfolio-level analyses and weekly cross-sectional regressions on all cryptocurrencies in our sample period,we provide evidence for a positive and statistically significant relationship between the maximum daily return within the previous month(MAX)and the expected returns on cryptocurrencies.In particular,the univariate portfolio analysis shows that weekly average raw and riskadjusted return differences between portfolios of cryptocurrencies with the highest and lowest MAX deciles are 3.03%and 1.99%,respectively.The results are robust with respect to the differences in size,price,momentum,short-term reversal,liquidity,volatility,skewness,and investor sentiment.展开更多
The international financial reporting standard for cash flow statement (IAS 7) provides options for the classification of certain cash flow items (arbitrary items). Therefore, business firms may classify the arbit...The international financial reporting standard for cash flow statement (IAS 7) provides options for the classification of certain cash flow items (arbitrary items). Therefore, business firms may classify the arbitrary items using the option that would maximize their own interest. This reduces the comparability of financial statements amongst business firms. This study aims to investigate the factors explaining management preferences in the selection of financial reporting practices on the arbitrary cash flow items. It concludes that managers tend to magnify the CFO reported in order to maximize the shareholders' wealth, which in turn would maximize their compensation. Managers of business firms with a relatively smaller size of CFO tend to classify interest paid and dividends paid as non-CFO in order to magnify their CFO. They also tend to classify interest received as CFO in order to inflate their relatively smaller size of CFO up to expectation. Similarly, managers of business firms with a relative larger size of dividends paid would classify the dividends paid outside CFO.展开更多
基金supported by the National Natural Science Foundation of China(72103115)the Humanities and Social Science Research General Project of the Ministry of Education of China(21XJC790008)+1 种基金the China Postdoctoral Science Foundation(2020T130393)the Social Science Foundation of Shaanxi Province,China(2021D028)。
文摘Climate change which is mainly caused by carbon emissions is a global problem affecting the economic development and well-being of human society.Low-carbon agriculture is of particular significance in slowing down global warming and reaching the goal of“carbon peak and carbon neutrality”.Therefore,taking straw incorporation as an example,this paper aims to investigate the impact of risk preferences on farmers’low-carbon agricultural technology(LCAT)adoption.Based on a two-phase micro-survey data of 1038 rice farmers in Jiangsu,Jiangxi,and Hunan provinces,this paper uses experimental economics methods to measure farmers’risk aversion and loss aversion to obtain the real risk preferences information of the farmers.We also explore the data to examine the actual LCAT adoption behavior of farmers.The results revealed that both risk aversion and loss aversion significantly inhibit farmers’LCAT adoption:more risk-averse or more loss-averse farmers are less likely to adopt LCAT.It is further found that crop insurance,farm scale and governmental regulations can alleviate the negative impact of risk aversion and loss aversion on farmers’LCAT adoption.Therefore,we propose that local governments need to promote low-carbon agricultural development by propagating the benefits of LCAT,extending crop insurance,promoting appropriate scale operations,and strengthening governmental regulations to promote farmers’LCAT adoption.
基金support from the National Natural Science Foundation of China(71861147003,71925009,72141014).
文摘This paper examined consumers’experiences in and preferences for plant-based meat(PBM)food and their respective correlates,based on data from an online survey of 579 consumers in four major cities in China in early 2021.We first described consumers’experiences in consuming and purchasing PBM food and their correlates,and then analyzed consumer preferences using hypothetical choice experiment.The experiment offered consumers various options to purchase burgers made from PBM or animal-based meat(ABM),combined with different countries of origin(COO),taste labels,and prices.Our data showed that respondents hold overall positive attitudes toward PBM food;85 and 82%of respondents reported experience in eating and purchasing PBM food,respectively.More than half of them ate PBM food because they wanted to try new food(58%),or were interested in healthy food(56%).Income,religion,and dietary restrictions were significantly correlated with consumers’experiences in PBM food consumption.Results from the Random Parameter Logit Model based on the hypothetical choice experiment data showed that 79%of respondents chose PBM burgers and were willing to pay an average of 88 CNY for a PBM burger.We also found that 99.8 and 83%of respondents are willing to buy burgers made in China and those with a taste label,with a willingness to pay(WTP)of 208 and 120 CNY,respectively.The heterogeneity test revealed that females and those with at least a bachelor’s degree,higher income,religious beliefs,and dietary restrictions are more likely to buy PBM burgers than their counterparts.
文摘Since the introduction of antiretroviral therapy, the life expectancy of people living with human immunodeficiency virus (PLWH) has extended. This extension has led to an increase in the aging population in Japan and globally. Providing appropriate long-term care (LTC) for PLWH has thus become increasingly critical. Our study aimed to describe LTC setting preferences and related factors among middle-aged and older Japanese people living with HIV. A cross-sectional survey was conducted at two hospitals in Tokyo. One hundred seventy-five outpatients aged 40 years and above participated in this study. Participants completed an anonymous self-administered questionnaire to assess where they wanted to live once they could no longer care for themselves. Approximately 52.0% preferred a designated facility for older adults or LTC, while 30.3% preferred their home or living with family, a partner, or a friend (“familiar housing”). Bivariate analyses revealed that LTC setting preference was significantly associated with marital status, whether or not the participant had at least one child, and household composition. Furthermore, logistic regression analysis revealed that participants living with non-kin were less likely to prefer living in designated housing facilities for older adults or LTC (adjusted odds ratio = 0.17, 95% confidence interval: 0.05 - 0.63). The study findings suggest that family make-up and composition of cohabiters are critical indicators for LTC setting preference in this population. These findings can be the foundation for future care planning and delivery to meet the unique LTC needs and expectations of the aging population with HIV in Japan and similar global settings.
文摘BACKGROUND Patients with Crohn’s disease(CD)are at risk of developing complications such as perianal fistulas.Patients with Crohn’s perianal fistulas(CPF)are affected by fecal incontinence(FI),bleeding,pain,swelling,and purulent perianal discharge,and METHODS This cross-sectional observational study was conducted in patients with CD aged 21-90 years via a web-enabled questionnaire in seven countries(April-August 2021).Patients were recruited into three cohorts:Cohort 1 included patients without perianal fistulas;cohort 2 included patients with perianal fistulas without fistula-related surgery;and cohort 3 included patients with perianal fistulas and fistula-related surgery.Validated patient-reported outcome measures were used to assess quality of life.Drivers of treatment preferences were measured using a discrete choice experiment(DCE).RESULTS In total,929 patients were recruited(cohort 1,n=620;cohort 2,n=174;cohort 3,n=135).Short Inflammatory Bowel Disease Questionnaire scores were worse for patients with CPF(cohorts 2 and 3)than for those with CD without CPF(cohort 1):Mean score 3.8 and 3.7 vs 4.1,respectively,(P<0.001).Similarly,mean Revised FI and FI Quality of Life scores were worse for patients with CPF than for those with CD without CPF.Quality of Life with Anal Fistula scores were similar in patients with CPF with or without CPF-related surgery(cohorts 2 and 3):Mean score 41 and 42,respectively.In the DCE,postoperative discomfort and fistula healing rate were the most important treatment attributes influencing treatment choice:Mean relative importance 35.7 and 24.7,respectively.CONCLUSION The burden of illness in CD is significantly higher for patients with CPF and patients rate lower postoperative discomfort and higher healing rates as the most desirable treatment attributes.
文摘Soymilk is one of the most available beverages, an alternative to dairy milk and is recognized for its nutritional value. The nutritional quality, the presence of anti-nutritional factors, isoflavones and sensory acceptability of soymilk depended on the soybean variety as well as the processing conditions. The soymilks from conventional and specialty Brazilian soybean cultivars were compared regarding the composition and consumer acceptance. There were significant differences on the protein, oil, sugars, isoflavones, presence of anti-nutritional factors (phytate and trypsin inhibitor activity) and NSI (nitrogen solubility index) among cultivars and soymilks and for sensory acceptance of soymilks. The preference mapping and cluster analysis identified three different segments of consumers. The soymilk from the conventional cultivar BRS284 achieved higher and similar acceptance score for the three consumer’s segments while the lipoxygenase free cultivars (BRS213 and BRS257) and specialty cultivar BRS216 showed higher score for two segments of consumers. The sensory evaluation of soymilk from different soybean cultivars could improve consumer uptake.
文摘Background:The midwife plays a critical role in health counselling and education,not just for women but also for their families and communities.At the current time,with the growth of the midwifery workforce globally,there is still a lack of understanding regarding the full scope and role of the midwife.Aim:To evaluate the current situation of knowledge of midwives’role among women in Makkah.In addition,this study identifies the effect of women’s knowledge on their preferences for receiving maternity care from health professionals.Methods:This study employed a descriptive quantitative cross-sectional method.The total resultant sample size(N)equalled 379 global respondents,of which 306,with a response rate=of 80.73%completed the entire survey as requested.An electronic questionnaire in the Arabic language was used in this study.Results:Results revealed that most women had incorrect knowledge regarding three aspects of the midwives’roles during pregnancy 53.9%,labour 52.8%and childbirth 61.9%.Also,results presented that most women preferred obstetricians to follow up on an uncomplicated pregnancy,labour,childbirth,and maternity care 69.6%,53.9%,64.7%and 46.1%,respectively.The study found that the women’s knowledge about midwives’roles affects their preferences for healthcare professionals in receiving maternity care(P<0.05).Conclusion:Responses showed that most participants had no experience and had negative views about midwives’roles.Thus,it would affect their health professionals’preferences for receiving maternity care.Therefore,midwifery services and maternity care professionals should prioritize educating women about midwives’competencies in maternity care.
基金supported by the National Natural Science Foundation of China Project(No.62302540)The Open Foundation of Henan Key Laboratory of Cyberspace Situation Awareness(No.HNTS2022020)+2 种基金Natural Science Foundation of Henan Province Project(No.232300420422)The Natural Science Foundation of Zhongyuan University of Technology(No.K2023QN018)Key Research and Promotion Project of Henan Province in 2021(No.212102310480).
文摘A deep learning access controlmodel based on user preferences is proposed to address the issue of personal privacy leakage in social networks.Firstly,socialusers andsocialdata entities are extractedfromthe social networkandused to construct homogeneous and heterogeneous graphs.Secondly,a graph neural networkmodel is designed based on user daily social behavior and daily social data to simulate the dissemination and changes of user social preferences and user personal preferences in the social network.Then,high-order neighbor nodes,hidden neighbor nodes,displayed neighbor nodes,and social data nodes are used to update user nodes to expand the depth and breadth of user preferences.Finally,a multi-layer attention network is used to classify user nodes in the homogeneous graph into two classes:allow access and deny access.The fine-grained access control problem in social networks is transformed into a node classification problem in a graph neural network.The model is validated using a dataset and compared with other methods without losing generality.The model improved accuracy by 2.18%compared to the baseline method GraphSAGE,and improved F1 score by 1.45%compared to the baseline method,verifying the effectiveness of the model.
文摘Introduction: Females with sickle cell disease (SCD), despite having a delayed pubertal development, are subject to many worries relating to their abilities to conceive, their capacity to maintain a maternofetal-risk-free pregnancy till term and give birth to healthy children without sickle cell disease. Knowing that unplanned pregnancies are more likely to increase maternofetal morbidity and mortality, we sought out to explore the pregnancy preferences in female patients with sickle cell disease to promote healthy conception and childbirth in this vulnerable population. Methodology: We conducted a cross-sectional study involving female patients of child-bearing age with sickle cell disease followed at Laquintinie Hospital Douala or who were members of a local sickle cell association. Pregnancy preferences were determined using the Desire to Avoid Pregnancy (DAP) scale. Factors associated with pregnancy preferences were determined using multivariable linear regression model. Threshold for significance was set at p Results: Seventy-seven patients were included with a mean age of 24.71 ± 5.53 years. Forty patients (51.95%) had one sexual partner and thirteen women (32.5%) used contraceptive methods. Most patients (46.0%) responded “Strongly Agree” or “Agree” to the statement “it would be a good thing for me if I became pregnant in the next 3 months”. The mean DAP score was 1.63 ± 0.91 [1.28 ± 0.82 in those who had a sexual partner and 1.99 ± 0.86 in those who had no sexual partner]. Factors that were positively associated with DAP score were students (b = 0.32, 95% CI [0.21, 0.95], p = 0.003), monthly income ≥ 100,000 FCFA (b = 0.24, 95% CI [0.07, 0.81], p = 0.022), and not having a sexual partner (b = 0.26, 95% CI [0.11, 0.85], p = 0.012). Conclusion: Most female patients with SCD have a low desire to avoid pregnancy. This is especially true for patients who are not students, have a partner and have a low monthly income.
基金the Natural Science Foundation of Inner Mongolia,China(2023JQ01)the National Key R&D Program of China(2019YFA0607103)+2 种基金the Central Government Guides Local Science and Technology Development Fund Projects(2022ZY0224)the Open Project Program of Ministry of Education Key Laboratory of Ecology and Resources Use of the Mongolian Plateau,Hohhot,Inner Mongolia,China(KF2023003)Major Science and Technology Project of Inner Mongolia Autonomous Region:Monitoring,Assessment and Early Warning Technology Research of Biodiversity in Inner Mongolia(2021ZD0011)for financial support.
文摘Many different factors,such as species traits,socio-economic factors,geographical and environmental factors,can lead to specimen collection preference.This study aims to determine whether grassland specimen collection in China is preferred by species traits(i.e.,plant height,flowering and fruiting period),environmental range(i.e.,the temperature and precipitation range)and geographical range(i.e.,distribution range and altitudinal range).Ordinary least squares models and phylogenetic generalized linear mixed models were used to analyze the relationships between specimen number and the explanatory variables.Random Forest models were then used to find the most parsimonious multivariate model.The results showed that interannual variation in specimen number between 1900 and 2020 was considerable.Specimen number of these species in southeast China was notably lower than that in northwest China.Environmental range and geographical range of species had significant positive correlations with specimen number.In addition,there were relatively weak but significant associations between specimen number and species trait(i.e.,plant height and flowering and fruiting period).Random Forest models indicated that distribution range was the most important variable,followed by flowering and fruiting period,and altitudinal range.These findings suggest that future floristic surveys should pay more attention to species with small geographical range,narrow environmental range,short plant height,and short flowering and fruiting period.The correction of specimen collection preference will also make the results of species distribution model,species evolution and other works based on specimen data more accurate.
文摘BACKGROUND Primary thumb carpometacarpal(CMC)osteoarthritis is one of the most common conditions encountered by hand surgeons.Of the vast number of operations that have been proposed,none have demonstrated results significantly superior to trapeziectomy alone.AIM The purpose of our study was to determine why surgeons opt for their technique in treating CMC arthritis.METHODS A cross-sectional survey of active members of the American Society for Surgery of the Hand was conducted to evaluate the reasons behind their preferred technique in the treatment of isolated thumb CMC arthritis.Surgeons were contacted by email once and provided with a link to a de-identified survey consisting of 5 treatment questions and 5 demographic questions.RESULTS Of 950 responses were received.40.5%of surgeons preferred trapeziectomy+ligament reconstruction tendon interposition(LRTI),followed by trapeziectomy+suspensionplasty(28.2%),suture button suspension(5.9%),trapeziectomy alone(4.6%),prosthetic arthroplasty(3.2%),arthrodesis(1.1%),and other(6.6%).Proponents of trapeziectomy+LRTI cited familiarity(73.2%),exposure during fellowship(48.8%)and less proximal migration(60%)to be the main reasons affecting their decision.Surgeons who preferred trapeziectomy+suspensionplasty most reported simplicity(74.9%),fewer complications(45.3%),less proximal migration(43.8%),and avoidance of autogenous tissue harvest(42.7%).Advocates of suture button suspension cited avoidance of autogenous tissue harvest(80.4%),shorter immobilization(76.8%),and quicker recovery(73.2%)with their technique.Advocates of trapeziectomy alone cited simplicity(97.7%),fewer complications(86.4%),and avoidance of autogenous tissue harvest(59.1%).In their comments,45%of surgeons choosing trapeziectomy alone cited evidence as an additional rationale.Advocates of prosthetic arthroplasty cited improved pinch strength(83.3%)and improved range of motion(63.3%),while those preferring arthrodesis cited better pinch strength(90%)and frequently in their comments,durability.Of the surgeons who preferred a technique other than LRTI,41.8%reported they had tried LRTI in the past,citing complexity of the procedure,flexor carpi radialis harvest,and longer operative time as reasons for moving on.CONCLUSION Our study provides an update on current treatment trends and offers new insight into the reasons behind surgeons'decision making in the management of thumb carpometacarpal osteoarthritis.Despite strong Level 1 evidence supporting the use of trapeziectomy alone,our findings demonstrate that most surgeons continue to supplement trapeziectomy with other techniques such as LRTI or suspensionplasty.Several factors including familiarity,personal experience(Level 4 evidence),and comfort may be more influential than Level 1 evidence in determining the techniques in a surgeon's armamentarium.Further prospective studies are needed to determine the optimal technique for surgical management of Eaton stages II-IV CMC arthritis and how these studies will affect surgeons’choice.
基金the financial support of National Key Research and Development Program of China(Grant No.2023YFB4202503)the Joint Funds of the National Natural Science Foundation of China(Grant No.U21A2072)+7 种基金Natural Science Foundation of China(Grant No.62274099)Natural Science Foundation of Tianjin(No.20JCQNJC02070)China Postdoctoral Science Foundation(No.2020T130317)the Overseas Expertise Introduction Project for Discipline Innovation of Higher Education of China(Grant No.B16027)Tianjin Science and Technology Project(Grant No.18ZXJMTG00220)Key R&D Program of Hebei Province(No.19214301D)provided by the Haihe Laboratory of Sustainable Chemical Transformationsthe Fundamental Research Funds for the Central Universities,Nankai University.
文摘Monolithic textured perovskite/silicon tandem solar cells(TSCs)are expected to achieve maximum light capture at the lowest cost,potentially exhibiting the best power conversion efficiency.However,it is challenging to fabricate high-quality perovskite films and preferred crystal orientation on commercially textured silicon substrates with micrometersize pyramids.Here,we introduced a bulky organic molecule(4-fluorobenzylamine hydroiodide(F-PMAI))as a perovskite additive.It is found that F-PMAI can retard the crystallization process of perovskite film through hydrogen bond interaction between F^(−)and FA^(+)and reduce(111)facet surface energy due to enhanced adsorption energy of F-PMAI on the(111)facet.Besides,the bulky molecular is extruded to the bottom and top of perovskite film after crystal growth,which can passivate interface defects through strong interaction between F-PMA+and undercoordinated Pb^(2+)/I^(−).As a result,the additive facilitates the formation of large perovskite grains and(111)preferred orientation with a reduced trap-state density,thereby promoting charge carrier transportation,and enhancing device performance and stability.The perovskite/silicon TSCs achieved a champion efficiency of 30.05%based on a silicon thin film tunneling junction.In addition,the devices exhibit excellent longterm thermal and light stability without encapsulation.This work provides an effective strategy for achieving efficient and stable TSCs.
文摘Female grasshoppers can affect the fitness of their offspring through their selection of oviposition site. Knowledge of soil type on oviposition, and its effects on subsequent development can provide guidelines for habitat manipulations that reduce the harmful effects of these pests on farmers fields. The influence of soil types on the oviposition site preference of variegated grasshopper (Zonocerus variegatus L.) reared some cassava (Manihot esculenta Crantz) varieties, was investigated in a cage trial carried out at the Bio factory laboratory, School of Agriculture and Food Sciences, Njala University, Sierra Leone during 2022/2023. The treatments comprised three soil types (Sandy, Loamy and Clay), each with three replications laid out in a randomized complete block design (RCBD) in wooden cages. Data were collected on the following development parameters including, Net reproductive growth ratio (R0), Generation time (Tc), Intrinsic rate of increase (rm), Finite rate of increase (), Doubling time (Dt), and overall survivorship. Findings revealed that, Z. variegatus L. preferred sandy soil in which, on average, most eggs were deposited (338, 6.62 4.40), followed by loamy soil, 286 (5.53 3.96), and then, clayey soil, 200 (3.91 3.85);though, the differences were not significant. This study established that Z. variegatus deposited more eggs in sandy soil > loamy soil > clayey soil, respectively;and subsequent survivorship of the immature unto mature adult insect, revealed a similar order. This indicates that the sandy soil is the most preferred substrate for oviposition and subsequent development into adult insects.
基金Shanghai Science and Technology Commission“R&D Public Service Platform and Institutional Capacity Improvement Project”,Grant/Award Number:21DZ2291300National Science and Technology Major Project,Grant/Award Number:2017ZX10304402-001-006 and 2017ZX10304402-001-012Start-on Funding from Shanghai Public Health Clinical Center,Grant/Award Number:KY-GW-2019-11,KYGW-2019-19 and KY-GW-2021-39。
文摘Background:Bitter taste receptors(Tas2rs)are generally considered to sense various bitter compounds to escape the intake of toxic substances.Bitter taste receptors have been found to widely express in extraoral tissues and have important physiological functions outside the gustatory system in vivo.Methods:To investigate the physiological functions of the bitter taste receptor cluster Tas2r106/Tas2r104/Tas2r105/Tas2r114 in lingual and extraoral tissues,multiple Tas2rs mutant mice and Gnat3 were produced using CRISPR/Cas9 gene-editing technique.A mixture containing Cas9 and sgRNA mRNAs for Tas2rs and Gnat3 gene was microinjected into the cytoplasm of the zygotes.Then,T7EN1 assays and sequencing were used to screen genetic mutation at the target sites in founder mice.Quantitative real-time polymerase chain reaction(qRT-PCR)and immunostaining were used to study the expression level of taste signaling cascade and bitter taste receptor in taste buds.Perception to taste substance was also studied using twobottle preference tests.Results:We successfully produced several Tas2rs and Gnat3 mutant mice using the CRISPR/Cas9 technique.Immunostaining results showed that the expression of GNAT3 and PLCB2 was not altered in Tas2rs mutant mice.But qRT-PCR results revealed the changed expression profile of m Tas2rs gene in taste buds of these mutant mice.With two-bottle preference tests,these mutant mice eliminate responses to cycloheximide due to genetic mutation of Tas2r105.In addition,these mutant mice showed a loss of taste perception to quinine dihydrochloride,denatonium benzoate,and cucurbitacin B(CuB).Gnat3-mediated taste receptor and its signal pathway contribute to CuB perception.Conclusions:These findings implied that these mutant mice would be a valuable means to understand the biological functions of TAS2Rs in extraoral tissues and investigate bitter compound-induced responses mediated by these TAS2Rs in many extraoral tissues.
基金supported by the National Science Foundation for Outstanding Youth of China(70925004)Fujian Province Transportation Hall of Science and Technology Development Projects,China(201319)the Science and Technology Project in Fujian Province Department of Education,China(JB14122)
文摘Case-based reasoning(CBR) is one of the best methods for generating an effective solution in an emergency. In recent years, some methods for generating emergency alternatives have been included in practical CBR applications, but there have been no in-depth studies of these processes. In this study,we propose a new method for dynamic case retrieval with subjective preferences and objective information, which considers the personal preferences of the decision makers and changes in the attributes of the emergency as the situation develops. First,we present a formula for calculating the case similarity and changing trends in the case considered, where similar cases are obtained. Next, we describe a method for measuring the overall assessment value with respect to similar historical cases, which is obtained by aggregating the case similarity, the utility case similarity, the first response time, and the implementation effect.The subjective preferences and objective information are also integrated in the decision-making process. Finally, we present a case study based on the emergency response to a fire in a highrise building, which illustrates the applicability and feasibility of the proposed method.
文摘Many agricultural landscapes have been formed through the interaction and co-evolution of nature and people, and represent the living landscapes shaped over time through intensive and continuous human cultivation. Terraced paddy fields are being re-evaluated to take into account the multiple functions they fill beyond only rice cultivation, particularly their contribution to the national biodiversity strategy of Japan. Since the 1990 s, terraced paddy fields have been considered a representative cultural landscape of Japan and, at the same time, multi-stakeholder conservation activities have been conducted throughout Japan to reverse the increasing abandonment of terraces. Shiroyone Senmaida is an outstanding cultural landscape and a major tourist attraction in Noto Peninsula, Ishikawa Prefecture, which was designated through an initiative by the Food and Agriculture Organization(FAO) as a Globally Important Agricultural Heritage Systems(GIAHS) pilot site in 2011. It is important to clarify tourist preference for terraced paddy field landscapes to contribute to future policy making toward improved agricultural landscape conservation. A key finding of this study is that tourists visiting toenjoy the agricultural landscape are also concerned on the sustainability of the farming methods and preferred to maintain the naturalness of the landscape. Respondents with higher educational levels and greater concern for the biological and traditional farming knowledge aspects of the rice terraces were also more inclined to favor sustainable farming practices. Tourists preferred to maintain the naturalness and rurality of the agricultural landscape, and indicated that construction of excessive tourist facilities would cause the landscape to deteriorate. It was suggested that the local community and surroundings, including rural settlements, hills, and forests, should also be conserved together with the scenic terrace.
文摘This study examined public attitudes concerning the value of outdoor spaces which people use daily. Two successive analyses were performed based on data from common residents and college students in the city of Hangzhou, China. First, citizens registered various items constituting desirable values of residential outdoor spaces through a preliminary questionnaire. The result proposed three general attributes (functional, aesthetic and ecological) and ten specific qualities of residential outdoor spaces. An analytic hierarchy process (AHP) was applied to an interview survey in order to clarify the weights among these attributes and qualities. Second, principal factors were extracted from the ten specific qualities with principal component analysis (PCA) for both the common case and the campus case. In addition, the variations of respondents’ groups were classified with cluster analysis (CA) using the results of the PCA. The results of the AHP application found that the public prefers the functional attribute, rather than the aesthetic attribute. The latter is always viewed as the core value of open spaces in the eyes of architects and designers. Fur-thermore, comparisons of ten specific qualities showed that the public prefers the open spaces that can be utilized conveniently and easily for group activities, because such spaces keep an active lifestyle of neighborhood communication, which is also seen to protect human-regarding residential environments. Moreover, different groups of respondents diverge largely in terms of gender, age, behavior and preference.
基金supported by the Major Program of the National Social Science Foundation of China under Grant No.17ZDA083the National Natural Science Foundation of China under Grant No.71932002the Natural Science Foundation of Beijing Municipality under Grant No.9192001.
文摘Considering that the assumption of time consistency does not adequately reveal the mechanisms of exit decisions of venture capital(VC),this study proposes two kinds of time-inconsistent preferences(i.e.,time-flow inconsistency and time-point incon-sistency)to advance research in this field.Time-flow inconsistency is in line with the previous time inconsistency literature,while time-point inconsistency is rooted in the VC fund’s finite lifespan.Based on the assumption about the strategies guiding future behaviors,we consider four types of venture capitalists:time-consistent,time-point-inconsistent,naïve,and sophisticated venture capitalists,of which the latter three are time-inconsistent.We derive and compare the exit thresholds of these four types of venture capitalists.The main results include:(1)time-inconsistent preferences acceler-ate the exits of venture capitalists;(2)the closer the VC funds expiry dates are,t`he more likely time-inconsistent venture capitalists are to accelerate their exits;and(3)future selves caused by time-flow inconsistency weaken the effect of time-point inconsist-ency.Our study provides a behavioral explanation for the empirical fact of young VCs’grandstanding.
文摘Over the last decade, the popularity of Transportation Network Companies (TNCs) as a mode of travel has been increasing at a steady pace. This trend <span style="font-family:Verdana;">highlights the importance of identifying the determinants that influence transportati</span><span style="font-family:Verdana;">on users to adopt TNCs as a preferred mode choice and the impacts of su</span><span style="font-family:Verdana;">ch preferences on their travel patterns and transportation network o</span><span style="font-family:Verdana;">peration. This paper reports on a recent study undertaken in Birmingham, AL aiming at understanding and documenting the factors that influence transportation users to select TNCs (such as Uber/Lyft) for completing typical day trips. In </span><span style="font-family:Verdana;">doing so, a travel diary questionnaire survey was developed in accordance with</span> <span style="font-family:Verdana;">the Institute of Transportation Engineers (ITE) Manual on Transportation Engineering Studies using the Qualtrics Research Core platform. The que</span><span style="font-family:Verdana;">stionnair</span><span style="font-family:Verdana;">e was used to survey over 450 transportation users in the Birmingham Metro area. The survey participants provided detailed trip information for a </span><span style="font-family:Verdana;">typical 24-hr day along with demographic data and travel preference informatio</span><span style="font-family:Verdana;">n. The survey responses provide high-resolution micro-level indicators </span><span style="font-family:Verdana;">of travel preferences and behaviors in a TNC-served area, which is a much-needed </span><span style="font-family:Verdana;">type of information for researchers and transportation planning agencies.</span>
文摘We investigate the significance of extreme positive returns in the cross-sectional pricing of cryptocurrencies.Through portfolio-level analyses and weekly cross-sectional regressions on all cryptocurrencies in our sample period,we provide evidence for a positive and statistically significant relationship between the maximum daily return within the previous month(MAX)and the expected returns on cryptocurrencies.In particular,the univariate portfolio analysis shows that weekly average raw and riskadjusted return differences between portfolios of cryptocurrencies with the highest and lowest MAX deciles are 3.03%and 1.99%,respectively.The results are robust with respect to the differences in size,price,momentum,short-term reversal,liquidity,volatility,skewness,and investor sentiment.
文摘The international financial reporting standard for cash flow statement (IAS 7) provides options for the classification of certain cash flow items (arbitrary items). Therefore, business firms may classify the arbitrary items using the option that would maximize their own interest. This reduces the comparability of financial statements amongst business firms. This study aims to investigate the factors explaining management preferences in the selection of financial reporting practices on the arbitrary cash flow items. It concludes that managers tend to magnify the CFO reported in order to maximize the shareholders' wealth, which in turn would maximize their compensation. Managers of business firms with a relatively smaller size of CFO tend to classify interest paid and dividends paid as non-CFO in order to magnify their CFO. They also tend to classify interest received as CFO in order to inflate their relatively smaller size of CFO up to expectation. Similarly, managers of business firms with a relative larger size of dividends paid would classify the dividends paid outside CFO.