A real time processing system of seismic waves using personal computers-Function and characteristics

Seismological Bureau of Sichuan Province, Chengdu 610041, China2) Center for Analysis and Prediction, State Seismological Bureau, Beijing 100036, China3) Observation Center for Prediction of Earthquakes and Volcanic Eruptions, Faculty of Sciences, Tohoku University, Sendai 98077, Japan

Acceleration of Points to Convex Region Correspondence Pose Estimation Algorithm on GPUs for Real-Time Applications

In our previous work, a novel algorithm to perform robust pose estimation was presented. The pose was estimated using points on the object to regions on image correspondence. The laboratory experiments conducted in the previous work showed that the accuracy of the estimated pose was over 99% for position and 84% for orientation estimations respectively. However, for larger objects, the algorithm requires a high number of points to achieve the same accuracy. The requirement of higher number of points makes the algorithm, computationally intensive resulting in the algorithm infeasible for real-time computer vision applications. In this paper, the algorithm is parallelized to run on NVIDIA GPUs. The results indicate that even for objects having more than 2000 points, the algorithm can estimate the pose in real time for each frame of high-resolution videos.

Acceleration of optical coherence tomography signal processing by multi-graphics processing units

A multi-GPU system designed for high-speed,real-time signal processing of optical coherencetomography(OCT)is described herein.For the OCT data sampled in linear wave numbers,themaximum procesing rates reached 2.95 MHz for 1024-OCT and 1.96 MHz for 2048-OCT.Data sampled using linear wavelengths were re-sampled using a time-domain interpolation method and zero-padding interpolation method to improve image quality.The maximum processing rates for1024-OCT reached 2.16 MHz for the time-domain method and 1.26 MHz for the zero-paddingmethod.The maximum processing rates for 2048-0CT reached_1.58 MHz,and 0.68 MHz,respectively.This method is capable of high-speed,real-time processing for O CT systems.

Letters A practical method of interpolation for real time processing

A simple way of interpolation for real time processing is pres -ented. For passive localization, the time delay between two signals can be determined by the peak of their cross-correlation. It is more efficient to estimate a cross-correlation function by the inverse FFT of the cross-spectral density. The original smapling rate is usually very low to reduce computation. The sampling rate of the cross-correlation so computed is too low to estimate satisfactorily and an interpolation procedure is therefore needed. The interpolation by zero augmented spectrum is concise, fast and accurate. The results of the computer simulation and real nuderwater signal processing are given in the paper.

Real time monitoring of bioreactor mAb IgG3 cell culture process dynamics via Fourier transform infrared spectroscopy： Implications for enabling cell culture process analytical technology

Compared to small molecule process analytical technology （PAT） applications, biotechnology product PAT applications have certain unique challenges and opportunities. Understanding process dynamics of bioreactor cell culture process is essential to establish an appropriate process control strategy for biotechnology product PAT applications. Inline spectroscopic techniques for real time monitoring of bioreactor cell culture process have the distinct potential to develop PAT approaches in manufac- turing biotechnology drug products. However, the use of inline Fourier transform infrared （FTIR） spectroscopic techniques for bioreactor cell culture process monitoring has not been reported. In this work, real time inline FTIR Spectroscopy was applied to a lab scale bioreactor mAb IgG3 cell culture fluid biomolecular dynamic model. The technical feasibility of using FTIR Spectroscopy for real time tracking and monitoring four key cell culture metabolites （including glucose, glutamine, lactate, and ammonia） and protein yield at increasing levels of complexity （simple binary system, fully formulated media, actual bioreactor cell culture process） was evaluated via a stepwise approach. The FTIR fingerprints of the key metabolites were identified. The multivariate partial least squares （PLS） calibration models were established to correlate the process FTIR spectra with the concentrations of key metabolites and protein yield of in-process samples, either individually for each metabolite and protein or globally for all four metabolites simultaneously. Applying the 2＇ld derivative pre-processing algorithm to the FTIR spectra helps to reduce the number of PLS latent variables needed significantly and thus simplify the interpretation of the PLS models. The validated PLS models show promise in predicting the concentration profiles of glucose, glutamine, lactate, and ammonia and protein yield over the course of the bioreactor cell culture process. Therefore, this work demonstrated the technical feasibility of real time monitoring of the bioreactor cell culture process via FTIR spectroscopy. Its implications for enabling cell culture PAT were discussed.