A Stochastic Model to Assess the Epidemiological Impact of Vaccine Booster Doses on COVID-19 and Viral Hepatitis B Co-Dynamics with Real Data

A patient co-infected with COVID-19 and viral hepatitis B can be atmore risk of severe complications than the one infected with a single infection.This study develops a comprehensive stochastic model to assess the epidemiological impact of vaccine booster doses on the co-dynamics of viral hepatitis B and COVID-19.The model is fitted to real COVID-19 data from Pakistan.The proposed model incorporates logistic growth and saturated incidence functions.Rigorous analyses using the tools of stochastic calculus,are performed to study appropriate conditions for the existence of unique global solutions,stationary distribution in the sense of ergodicity and disease extinction.The stochastic threshold estimated from the data fitting is given by:R_(0)^(S)=3.0651.Numerical assessments are implemented to illustrate the impact of double-dose vaccination and saturated incidence functions on the dynamics of both diseases.The effects of stochastic white noise intensities are also highlighted.

The development of real time data driving multi-axis linkage and synergic movement control system of 3D variable cross-section roll forming machine

The three dimensional variable cross-section roll forming is a kind of new metal forming technol- ogy which combines large forming force, multi-axis linkage movement and space synergic movement, and the sequential synergic movement of the ganged roller group is used to complete the metal sheet forming according to the shape of the complicated and variable forming part data. The control system should meet the demands of quick response to the test requirements of the product part. A new kind of real time data driving multi-axis linkage and synergic movement control strategy of 3D roll forming is put forward in the paper. In the new control strategy, the forming data are automatically generated according to the shape of the parts, and the multi-axis linkage movement together with cooperative motion among the six stands of the 3D roll forming machine is driven by the real-time information, and the control nodes are also driven by the forming data. The new control strategy is applied to a 48 axis 3D roll forming machine developed by our research center, and the control servo period is less than 10ms. A forming experiment of variable cross section part is carried out, and the forming preci- sion is better than ＋ 0.5mm by the control strategy. The result of the experiment proves that the control strategy has significant potentiality for the development of 3D roll forming production line with large scale, multi-axis ganged and svner^ic movement

Screening and reconstruction of real-time traffic data

The quality of real time traffic information is of the great importance, therefore the factors having effect on traffic characteristics are analyzed in general, and the necessities of real time data processing are summarized. The identification and reconstruction of real time traffic data are analyzed using Kalman filter equation and statistical approach. Four methods for ITS (Intelligent transportation system) detector data screening in traffic management systems are discussed in detail. Meanwhile traffic data examinations are discussed with solutions formulated through analysis, and recommendations are made for information collection and data management in future.

Quality control of marine big data——a case study of real-time observation station data in Qingdao

Offshore waters provide resources for human beings,while on the other hand,threaten them because of marine disasters.Ocean stations are part of offshore observation networks,and the quality of their data is of great significance for exploiting and protecting the ocean.We used hourly mean wave height,temperature,and pressure real-time observation data taken in the Xiaomaidao station(in Qingdao,China)from June 1,2017,to May 31,2018,to explore the data quality using eight quality control methods,and to discriminate the most effective method for Xiaomaidao station.After using the eight quality control methods,the percentages of the mean wave height,temperature,and pressure data that passed the tests were 89.6%,88.3%,and 98.6%,respectively.With the marine disaster(wave alarm report)data,the values failed in the test mainly due to the influence of aging observation equipment and missing data transmissions.The mean wave height is often affected by dynamic marine disasters,so the continuity test method is not effective.The correlation test with other related parameters would be more useful for the mean wave height.

Smear-Negative Multidrug-Resistant Tuberculosis a Significance Hidden Problem for MDR-TB Control: An Analysis of Real World Data

Purpose: The drug resistance pattern in tuberculosis (TB) is still under investigated. We analyzed the clinical data from the patients with smear positive TB and applied the model to predict the patients with smear-positive TB. Materials and Methods: Medical records information of 6977 cases was included from 11,950 inpatients from January 2009 to November 2013. The cases data were divided into a training set, test set and prediction set. Logistic regression analysis was applied to the training set data to establish a prediction classification model, the effect of which was then evaluated using the test set by receiver operating characteristic (ROC) analysis. The model was then applied to the prediction set to identify incidence of snMDR-TB. Results: Sixteen factors which correlate with MDR-TB-including frequency of hospitalization, province of origin, anti-TB drugs, and complications, were identified from the comparison between SP-TB and spMDR-TB. The area under the ROC curve (AUC) of the prediction model was 0.752 (sensitivity = 61.3%, specificity = 83.3%). The percentage of all inpatients with snMDR-TB (snMDR-TB/Total) was 28.7% ± 0.02%, while that of all SN-PTB with snMDR-TB (snMDR-TB/SN-PTB) was 26.5% ± 0.03%. The ratio of snMDR-TB to MDR-TB (snMDR-TB/MDR-TB) was 2.09 ± 0.33. Conclusion: snMDR-TB as an important source of MDR-TB is a significant hidden problem for MDR-TB control and can be identified by the prediction model. A kind of vicious circle with a certain delay effect exists between snMDR-TB and MDR-TB. To better control MDR-TB, it is necessary to pay greater attention to snMDR-TB, conduct further research and develop targeted therapeutic strategies.

Real Time Data Analysis of West Rapti River Basin of Nepal

Floods are the most widespread climate-related hazards in the world, and they impact more people globally than any other type of natural disasters. It causes over one third of the total economic loss from natural catastrophes and is responsible for two thirds of people affected by natural disasters. On the other hand, studies and analysis have shown that damage reductions due to forecasts improvements can range from a few percentage points to as much as 35% of annual flood damages. About 300 people lose their lives each year due to floods and landslides in Nepal with property damage exceeding 626 million NPR on average. The West Rapti River basin is one of the most flood prone river basins in Nepal. The real-time flood early warning system together with the development of water management and flood protection schemes plays a crucial role in reducing the loss of lives and properties and in overall development of the basin. The non-structural mitigating measure places people away from flood. This method is designed to reduce the impact of flooding to society and economy. This paper presents an overview of flood problems in the West Rapti River basin, causes and consequences of recent floods and the applicability and effectiveness of the real time data to flood early warning in Nepal.

Real traffic-data based evaluation of vehicular traffic environment and state- of-the-art with future issues in location-centric data dissemination for VANETs

Extensive investigation has been performed in location-centric or geocast routing protocols for reliable and efficient dissemination of information in Vehicular Adhoc Networks （VANETs）. Various location-centric routing protocols have been suggested in literature for road safety ITS applications considering urban and highway traffic environment. This paper characterizes vehicular environments based on real traffic data and investigates the evolution of location-centric data dissemination. The current study is carded out with three main objectives： （i） to analyze the impact of dynamic traffic environment on the design of data dissemination techniques, （ii） to characterize location-centric data dissemination in terms of functional and qualitative behavior of protocols, properties, and strengths and weaknesses, and （iii） to find some future research directions in information dissemination based on location. Vehicular traffic environments have been classified into three categories based on physical characteristics such as speed, inter-vehicular distance, neighborhood stability, traffic volume, etc. Real traffic data is considered to analyze on-road traffic environments based on the measurement of physical parameters and weather conditions. Design issues are identified in incorporating physical parameters and weather conditions into data dissemination. Functional and qualitative characteristics of location-centric techniques are explored considering urban and highway environments. Comparative analysis of location-centric techniques is carded out for both urban and highway environments individually based on some unique and common characteristics of the environments. Finally, some future research directions are identified in the area based on the detailed investigation of traffic environments and location-centric data dissemination techniques.

Real-time crash prediction on freeways using data mining and emerging techniques

Recent advances in intelligent transportation system allow traffic safety studies to extend from historic data-based analyses to real-time applications. The study presents a new method to predict crash likelihood with traffic data collected by discrete loop detectors as well as the web-crawl weather data. Matched case-control method and support vector machines （SVMs） technique were employed to identify the risk status. The adaptive synthetic over-sampling technique was applied to solve the imbalanced dataset issues. Random forest technique was applied to select the contributing factors and avoid the over-fitting issues. The results indicate that the SVMs classifier could successfully classify 76.32% of the crashes on the test dataset and 87.52% of the crashes on the overall dataset, which were relatively satisfactory compared with the results of the previous studies. Compared with the SVMs classifier without the data, the SVMs classifier with the web-crawl weather data increased the crash prediction accuracy by 1.32% and decreased the false alarm rate by 1.72%, showing the potential value of the massive web weather data. Mean impact value method was employed to evaluate the variable effects, and the results are identical with the results of most of previous studies. The emerging technique based on the discrete traffic data and web weather data proves to be more applicable on real- time safety management on freeways.

Sentiment Drift Detection and Analysis in Real Time Twitter Data Streams

Handling sentiment drifts in real time twitter data streams are a challen-ging task while performing sentiment classifications,because of the changes that occur in the sentiments of twitter users,with respect to time.The growing volume of tweets with sentiment drifts has led to the need for devising an adaptive approach to detect and handle this drift in real time.This work proposes an adap-tive learning algorithm-based framework,Twitter Sentiment Drift Analysis-Bidir-ectional Encoder Representations from Transformers(TSDA-BERT),which introduces a sentiment drift measure to detect drifts and a domain impact score to adaptively retrain the classification model with domain relevant data in real time.The framework also works on static data by converting them to data streams using the Kafka tool.The experiments conducted on real time and simulated tweets of sports,health care andfinancial topics show that the proposed system is able to detect sentiment drifts and maintain the performance of the classification model,with accuracies of 91%,87%and 90%,respectively.Though the results have been provided only for a few topics,as a proof of concept,this framework can be applied to detect sentiment drifts and perform sentiment classification on real time data streams of any topic.

Web-based GIS System for Real-time Field Data Collection Using Personal Mobile Phone

Recently, use of mobile communicational devices in field data collection is increasing such as smart phones and cellular phones due to emergence of embedded Global Position System GPS and Wi-Fi Internet access. Accurate timely and handy field data collection is required for disaster management and emergency quick responses. In this article, we introduce web-based GIS system to collect the field data by personal mobile phone through Post Office Protocol POP3 mail server. The main objective of this work is to demonstrate real-time field data collection method to the students using their mobile phone to collect field data by timely and handy manners, either individual or group survey in local or global scale research.

A review on research of real estate big data

The research value and market potentials of "big data" in real estate industry are well acknowledged with the development of technologies. But research in this area is far away from systematic and thorough context. Aiming at this issue, we systematically examined the research outcomes related to real estate big data. It gives a comment to current research status and proposes the future directions in this area from the four aspects, i.e. the hierarchical structuring of real estate "Big Data", integrated implementation, exchange and pricing systems, and the market operation system, in order to assist the researchers for their future works.

Study on Rear-end Real-time Data Quality Control Method of Regional Automatic Weather Station

[Objective] The aim was to study the rear-end real-time data quality control method of regional automatic weather station. [Method] The basic content and steps of rear-end real-time data quality control of regional automatic weather station were introduced. Each element was treated with systematic quality control procedure. The existence of rear-end real time data of regional meteorological station in Guangxi was expounded. Combining with relevant elements and linear changes, improvement based on traditional quality control method was made. By dint of evaluation and relevant check of element, the quality of temperature and pressure was controlled. [Result] The method was optimized based on traditional quality control method, and it narrowed the effectiveness of real-time data quality control. The quality check of hourly precipitation applied relevant check of hourly minimum temperature, vertical consistency check of radar data, which can effectively improve the accuracy and credibility of hourly precipitation quality control. [Conclusion] The method was on trial for one year in the quality control of real-time data in the regional automatic meteorological station in Guangxi and had gained good outcome.

Real-time performance of periodic data transmission in EPA industrial Ethernet

To evaluate and improve the real-time performance of Ethernet for plant automation（EPA） industrial Ethernet,the real-time performance of EPA periodic data transmission was theoretically and experimentally studied.By analyzing information transmission regularity and EPA deterministic scheduling mechanism,periodic messages were categorized as different modes according to their entering-queue time.The scheduling characteristics and delivery time of each mode and their interacting relations were studied,during which the models of real-time performance of periodic information transmission in EPA system were established.On this basis,an experimental platform is developed to test the delivery time of periodic messages transmission in EPA system.According to the analysis and the experiment,the main factors that limit the real-time performance of EPA periodic data transmission and the improvement methods were proposed.

Alternate Data Acquisition and Real-time Monitoring System on HT-7 Tokamak

A new system called alternate data acquisition and real-time monitoring system has been developed for long-time discharge in tokamak operation. It can support continuous on-line data acquisition at a high sampling rate and a graphic display of the plasma parameters during the discharge. Thus operators can monitor and control the plasma state in real time. An application of this system has been demonstrated on the HT-7 tokamak.

Quality Control System of Meteorological Real-time Data from Automatic Weather Stations in Shandong

The quality control system for meteorological real-time data from automatic weather stations in Shandong realized integration of communi- cation system and provincial quality control system, and an interaction platform which was mainly created by Web was set up. The system not only was fully guaranteed for the funning of basic business, also improved the reliability of the data.

Integrated Real-Time Big Data Stream Sentiment Analysis Service

Opinion (sentiment) analysis on big data streams from the constantly generated text streams on social media networks to hundreds of millions of online consumer reviews provides many organizations in every field with opportunities to discover valuable intelligence from the massive user generated text streams. However, the traditional content analysis frameworks are inefficient to handle the unprecedentedly big volume of unstructured text streams and the complexity of text analysis tasks for the real time opinion analysis on the big data streams. In this paper, we propose a parallel real time sentiment analysis system: Social Media Data Stream Sentiment Analysis Service (SMDSSAS) that performs multiple phases of sentiment analysis of social media text streams effectively in real time with two fully analytic opinion mining models to combat the scale of text data streams and the complexity of sentiment analysis processing on unstructured text streams. We propose two aspect based opinion mining models: Deterministic and Probabilistic sentiment models for a real time sentiment analysis on the user given topic related data streams. Experiments on the social media Twitter stream traffic captured during the pre-election weeks of the 2016 Presidential election for real-time analysis of public opinions toward two presidential candidates showed that the proposed system was able to predict correctly Donald Trump as the winner of the 2016 Presidential election. The cross validation results showed that the proposed sentiment models with the real-time streaming components in our proposed framework delivered effectively the analysis of the opinions on two presidential candidates with average 81% accuracy for the Deterministic model and 80% for the Probabilistic model, which are 1% - 22% improvements from the results of the existing literature.

Data Transfer Over the Internet for Real Time Applications

Efficient real time data exchange over the Internet plays a crucial role in the successful application of web-based systems. In this paper, a data transfer mechanism over the Internet is proposed for real time web based applications. The mechanism incorporates the eXtensible Markup Language （XML） and Hierarchical Data Format （HDF） to provide a flexible and efficient data format. Heterogeneous transfer data is classified into light and heavy data, which are stored using XML and HDF respectively; the HDF data format is then mapped to Java Document Object Model （JDOM） objects in XML in the Java environment. These JDOM data objects are sent across computer networks with the support of the Java Remote Method Invocation （RMI） data transfer infrastructure. Client＇s defined data priority levels are implemented in RMI, which guides a server to transfer data objects at different priorities. A remote monitoring system for an industrial reactor process simulator is used as a case study to illustrate the proposed data transfer mechanism.

基于真实世界数据的注射泵临床使用有效性评价研究

目的基于真实世界数据(Real World Data,RWD)对注射泵的主要有效性评价功能进行研究,最大程度反映其临床实践中的真实性能表现,以建立科学有效的评价方法。方法选取本院重症医学科3种品牌(M、F、L)注射泵共计37台次作为研究对象,根据建立的临床使用评价指标,分别在5、25和50 mL/h 3种流速下,获得注射泵出第1滴液的时间和响应时间来测试注射泵快速启动的性能差异,计算流速平均值、相对示值误差和示值重复性来测试注射泵注射精度的性能差异;分别在5、10和15 mL/h 3种流速下,获得注射泵的流速波动下限和间歇时间来测试注射泵联机中继的性能差异。结果在快速启动功能方面,设定流速越大,注射泵出第1滴液的时间和响应时间越短,且在3种流速下,M品牌注射泵出第1滴液的时间和响应时间都最短(P<0.05)。在注射精度功能方面,在3种流速下,M和L品牌的流速控制性能和示值稳定性都显著优于F品牌(P<0.05)。在联机中继功能方面,人工模拟联机中继功能导致的流速波动下限和间歇时间差异显著(P<0.05),且设定流速越大,实时流速从下降到恢复设定值需要的间歇时间就越短。另外,M品牌的自动联机中继功能可有效解决前序泵与后序泵中继过程中产生的药物流量抖动或间断,但有瞬时流速上升,相对能够保证药物流量的稳定性和连续性。结论使用正确的基于RWD的注射泵临床使用评价方法不仅能够规范临床应用行为,还能够为注射泵的评价、准入/淘汰和集中采购/价格谈判提供数据支撑。

基于改进遗传算法的2型糖尿病中医药有效处方推荐方法研究

目的改进遗传算法创新推荐度模型,以2型糖尿病(T2DM)电子病历数据为基础进行核心处方挖掘及有效处方推荐。方法基于真实世界电子病历数据,构建T2DM患者有效处方集及不同证型原始处方集数据库;对遗传算法进行改进,优化适应度函数的构建,使提取出的核心有效处方朝着有效处方集的方向进化;基于核心有效处方与原始处方集的相似度关系,创新推荐度模型,通过遍历不同证型原始处方集进行处方推荐度挖掘。结果共使用有效诊疗标准的处方17712条,提取的核心有效处方中包含中药37种;最终挖掘出满足“推荐度≥85%”的处方26条,最大推荐度为97.26%。结论研究改进遗传算法提高了对中药处方集的特征提取和全局搜索能力,并通过提出新的推荐度模型进行临床处方决策推荐,提高了电子病历数据的利用率。