Established and Emerging Optical Technologies for the Real-Time Detection of Cervical Neoplasia: A Review

Cervical cancer remains a critically important problem for women, especially those women in the developing world where the case-fatality rate is high. There are an estimated 528,000 cases and 266,000 deaths worldwide. Established screening and detection programs in the developed world have lowered the mortality from 40/100,000 to 2/100,000 over the last 60 years. The standard of care has been and continues to be: a screening Papanicolaou smear with or without Human Papilloma Virus (HPV) testing;followed by colposcopy and biopsies and if the smear is abnormal;and followed by treatment if the biopsies show high grade disease (cervical intraepithelial neoplasia (CIN) grades 2 and 3 and Carcinoma-in-situ). Low grade lesions (Pap smears with Atypical Cells of Uncertain Significance (ASCUS), Low Grade Squamous Intraepithelial Lesions (LGSIL), biopsies showing HPV changes or showing CIN 1);are usually followed for two years and then treated if persistent. Treatment can be performed with loop excision, LASER, or cryotherapy. Loop excision yields a specimen which can be reviewed to establish the diagnosis more accurately. LASER vaporizes the lesion and cryotherapy leads to tissue destruction. Under long term study;loop excision, LASER, and cryotherapy have the same rate of cure. The standard of care is expensive and takes 6 - 12 weeks for the individual patient. During the last twenty years, new technologies that can view the cervix and even image the cervix with cellular resolution have been developed. These technologies could lead to a new paradigm in which diagnosis and treatment occurs at a single visit. These technologies include fluorescence and reflectance spectroscopy (probe or wide-field, whole cervix scanning approaches) and fluorescence confocal endomicroscopy or high resolution micro-endoscopy. Both technologies have received Federal Drug Administration (FDA) and have been commercialized. Research trials continue to show their remarkable performance. These technologies are reviewed and clinical trials are summarized. Emerging technologies are coming along that may compete with those already approved and include optical coherence tomography, optical coherence tomography with autofluorescence, diffuse optical microscopy, and dual mode micro-endoscopy. These technologies are also reviewed and where available, clinical data is reported. Optical technologies are ready to diffuse into clinical practice because they will save money and 3 or 4 visits in the developed world and offer the same standard of care to the developing world where more cervical cancer exists.

Applying real-time control to enhance the performance of nitrogen removal in CAST system

A bench-scale reactor（72 L） red with domestic sewage, was operated more than 3 months with three operation modes： traditional mode, modified mode and real-time control mode, so as to evaluate effects of the operation mode on the system performance and to develop a feasible control strategy. Results obtained from fixed-time control study indicate that the variations of the pH and oxidation-reduction potential（ORP） profiles can represent dynamic characteristics of system and the cycle sequences can be controlled and optimized by the control points on the pH and ORP profiles. A control strategy was, therefore, developed and applied to real-time control mode. Compared with traditional mode, the total nitrogen（TN） removal can be increased by approximately 16% in modified mode and a mean TN removal of 92% was achieved in real-time control mode. Moreover, approximately 12.5% aeration energy was saved in real- time control mode. The result of this study shows that the performance of nitrogen removal was enhanced in modified operation mode. Moreover, the real-time control made it possible to optimize process operation and save aeration energy.

Diagnosis of Mycobacterium tuberculosis using molecular biology technology

Objective:To present an integrated molecular biology dedicated system for tuberculosis diagnosis.Methods:One hundred and five sputum specimens from patients strongly suspected by clinical parameters of tuberculosis were studied by Ziehl-Neelsen staining,by cultivation on solid medium and by a balanced hemincsted fluorometric PCR system(Orange C3TB) that could preserve worker safety and produce a rather pure material free of potential inhibitors. DNA amplification was performed in a low cost tuberculosis termocycler-fluorotneter.Produced double stranded DNA was flurometrically detected.The whole reaction was conducted in one single tube which would not be opened after adding the processed sample in order to minimize the risk of cross contamination with amplicons.Results:The assay was able to delect 30 bacillus per sample mL with 99.8%interassay variation coefficient.PCR was positive in 23(21.9%) tested samples(21 of them were smear negative).In our study it showed a preliminary sensitivity of 94.5%for sputum and an overall specificity of 98.7%.Conclusions:Total run time of the test is 4 h with 2.5 real working time.All PCR positive samples are also positive by microbiological culture and clinical criteria.Results show that it could be a very useful tool to increase detection efficiency of tuberculosis disease in low bacilus load samples.Furthermore,its low cost and friendly using make it feasible to run in poor regions.

Simple, Flexible, and Interoperable SCADA System Based on Agent Technology

SCADA (Supervisory Control and Data Acquisition) is concerned with gathering process information from industrial control processes found in utilities such as power grids, water networks, transportation, manufacturing, etc., to provide the human operators with the required real-time access to industrial processes to be monitored and controlled either locally (on-site)or remotely (i.e., through Internet). Conventional solutions such as custom SCADA packages, custom communication protocols, and centralized architectures are no longer appropriate for engineering this type of systems because of their highly distribution and their uncertain continuously changing working environments. Multi-agent systems (MAS) appeared as a new architectural style for engineering complex and highly dynamic applications such as SCADA systems. In this paper, we propose an approach for simply developing flexible and interoperable SCADA systems based on the integration of MAS and OPC process protocol. The proposed SCADA system has the following advantages: 1) simple (easier to be implemented);2) flexible (able to adapt to its environment dynamic changes);and 3) interoperable (relative to the underlying control systems, which belongs to diverse of vendors). The applicability of the proposed approach is demonstrated by a real case study example carried out in a paper mill.

Development of PC Worker’s Management System in PC Training Room and Office by Using IoT Technology

At present time, there has been a demand for management systems that can survey and monitor a PC （personal computer） practice room, movement of people in an office, situation of utilization of facilities and so on in real time without causing psychological stress. For example, PC administrators in Japanese national educational institutions must report operation status of PC practice rooms once a year. But, there is currently no system for automatically recording PC operating situations. Therefore, the burden on the PC administrators is big. In this study, we aimed at systems for accurately managing the sitting and work time without psychologically stressing PC users. This time, we propose uniform management systems of sitting and work time using smart tap node and mat sensor node by IoT （Internet of Things） technology. The smart tap was connected to PCs to acquire the operating status of the PCs. In parallel with this smart tap, the mat sensor was used to acquire human presence state. By calculating binary data representing the PC operating status and human presence state from the two sensing data （smart tap and mat sensor） by the proposed technique, we can exactly calculate wasteful power consumption etc. The use of IoT technology makes it unnecessary to use large installation services when introducing our system. Therefore, this our proposal system can be easily installed even by unskilled workers.

Applying Global Positioning System Real-Time Kinematic Technology to Collection and Analysis of Rowing Information

To obtain higher accuracy of information concerning boat motion, the use of global positioning system (GPS) real-time kinematic (RTK) technology was investigated. Through RTK technology, a measurement precision of the ±1 cm range can be achieved. The research equipment included a GPS receiver and a personal digital assistant as a data control and processing unit. Real-time GPS data was captured and processed to acquire various parameters, including the boat track, velocity curve, stroke rate, and stroke distance. Using this data, the quantitative information related to rowing training can be achieved. The results are helpful for analyzing the biomechanical parameters of rowing techniques and for evaluating training efficiency.

英国数学英才选拔考试MAT命题技术分析

数学入学考试MAT是英国重要的数学英才选拔考试,是牛津等大学数学、计算机及相关专业的入学条件之一,数学知识与方法相当于A水平核心数学C1和C2模块水平,但问题设计却不同,重在考查考生理解A水平数学的深度而非广度.MAT的命题特征是：控制运算量,解题思维多样;分层递进设计,考查数学探究能力;构建新情境,渗透数学建模思想,考核信息加工能力;因循专业所需,甄别不同数学能力.

Comprehensive and personalized approach is a critical area for developing remote cardiac rehabilitation programs

In the evolving landscape of cardiac rehabilitation(CR),adopting digital technologies,including synchronous/real-time digital interventions and smart applications,has emerged as a transformative approach.These technologies offer realtime health data access,continuous vital sign monitoring,and personalized educational enhanced patient self-management and engagement.Despite their potential benefits,challenges and limitations exist,necessitating careful consideration.Synchronous/real-time digital CR involves remote,two-way audiovisual communication,addressing issues of accessibility and promoting home-based interventions.Smart applications extend beyond traditional healthcare,providing real-time health data and fostering patient empowerment.Wearable devices and mobile apps enable continuous monitoring,tracking of rehabilitation outcomes,and facilitate lifestyle modifications crucial for cardiac health maintenance.As digital CR progresses,ensuring patient access,equitable implementation,and addressing the digital divide becomes paramount.Artificial intelligence holds promise in the early detection of cardiac events and tailoring patient-specific CR programs.However,challenges such as digital literacy,data privacy,and security must be addressed to ensure inclusive implementation.Moreover,the shift toward digital CR raises concerns about cost,safety,and potential depersonalization of therapeutic relationships.A transformative shift towards technologically enabled CR necessitates further research,focusing not only on technological advancements but also on customization to meet diverse patient needs.Overcoming challenges related to cost,safety,data security,and potential depersonalization is crucial for the widespread adoption of digital CR.Future studies should explore integrating moral values into digital therapeutic relationships and ensure that digital CR is accessible,equitable,and seamlessly integrated into routine cardiac care.Theoretical frameworks that accommodate the dynamic quality of real-time monitoring and feedback feature of digital CR interventions should be considered to guide intervention development.

文野形构--华中科技大学的武陵干栏研究40年

2024年1月20日在四川李庄成功举办的“中国民居--传统居住形态研究展”上,华中科技大学团队以武陵干栏为主题,展出了其深耕武陵40年的研究脉络,包括“致敬传统”“武陵干栏研究进行时”“未来发展趋向”等版块。在此契机下,文章试图回溯华中科技大学民居研究的若干重要阶段,梳理研究团队40年来从经典史论转向田野实证、深耕营造技艺体系化调查并面向当代乡土实践的奋进线索。

人工智能技术在教学设计制作中的应用与实践

随着时代的发展,人工智能技术助推了线上教育的发展,但如今的微课制作质量忽高忽低,不仅存在操作繁琐、耗时长等问题,还不能激发起学生的学习兴趣。本文设计了基于AI技术的微课制作平台,该平台可辅助老师制作微课,在一定程度上节省了时间,简化了过程,并且系统后台能够自动生成品质高的微课视频,有效提升了微课的使用率与质量。

A virtual 3D interactive painting method for Chinese calligraphy and painting based on real-time force feedback technology

A novel 3D interactive painting method for Chinese calligraphy and painting based on force feedback technology is proposed. The relationship between the force exerted on the brush and the resulting brush deformation is analyzed and a spring-mass model is used to build a model of the 3D Chinese brush. The 2D brush footprint between the brush and the plane of the paper or object is calculated according to the deformation of the 3D brush when force is exerted on the 3D brush. Then the 3D brush footprint is obtained by projecting the 2D brush footprint onto the surface of the 3D object in real time, and a complete 3D brushstroke is obtained by superimposing 3D brush footprints along the painting direction. The proposed method has been suc- cessfully applied in a virtual 3D interactive drawing system based on force feedback technology. In this system, users can paint 3D brushstrokes in real time with a Phantom Desktop haptic device, which can effectively serve as a virtual reality interface to the simulated painting environment for users.

One-time Shaping Technological System of Lightweight Roof Greening

Lightweight roof greening is an important way for improving urban ecological environment and has good ecological and social benefits, but the investment is- too-high for the investors. Therefore, it is necessary to improve the system of lightweight roof greening. This study introduced a lightweight roof greening mode with low cost, simple construction, rapid formation, good economic benefit and convenient curing.

3-D Animation as Applied to the Solving of Coupling Relations in the 6-DOF Parallel Robot

How to solve the coupling relations in a 6 - DOF parallel robot quickly and accurately within the limits of realtime control is a critical problem. In traditional analytic method, the complicated mathemtical model must first be constructed and then solved by programming.Obviously, this method is not very practical. This paper,therefore, proposes a new way of approach with a new method using 3- D animation for the solving of coupling relations in the 6 - DOF parallel robot. This method is much simpler and its solving accuracy approaches that of the more complicated analytic method.

人工智能抠像技术在影视后期制作中的应用与探讨

抠像技术是影视后期制作中的重要环节,随着计算机的算力逐年提升和各行业大数据的积累,人工智能(Artificial Intelligence,AI)技术在各个领域进行了不断探索和发展,特别是在影视行业中的计算机视觉方面得到了广泛运用。AI技术与影视的结合,不仅可以提高制作效率,还能为观众带来更好的观影体验。文章讲解人工智能抠像技术在影视后期制作中的应用,并从AI技术抠像优势、关键技术分析和应用前景共3个方面进行阐述。

An IoT-Based Aquaculture Monitoring System Using Firebase

Indonesia is a producer in the fisheries sector,with production reaching 14.8 million tons in 2022.The production potential of the fisheries sector can be optimally optimized through aquaculture management.One of the most important issues in aquaculture management is how to efficiently control the fish pond water conditions.IoT technology can be applied to support a fish pond aquaculture monitoring system,especially for catfish species(Siluriformes),in real-time and remotely.One of the technologies that can provide this convenience is the IoT.The problem of this study is how to integrate IoT devices with Firebase’s cloud data system to provide reliable and precise data,which makes it easy for fish cultivators to monitor fishpond conditions in real time and remotely.The IoT aquaculture fishpond monitoring use 3 parameters:(1)water temperature;(2)pHwater level;and(3)turbidity level of pond water.IoT devices use temperature sensors,pH sensors,and turbidity sensors,which are integrated with a microcontroller and Wi-Fi module.Data from sensor readings are sent to the Firebase cloud via theWi-Fi module so that it can be accessed in real time by end users with an Androidbased mobile app.The findings are(1)the IoT-based aquaculture monitoring system device has a low error rate in measuring temprature,pH,and turbidity with a percentage of 1.75%,1.94% and 9.78%,respectively.Overall,the total average error of the three components is 4.49%;(2)in cost analysis,IoT-based has a cost-effectiveness of 94.21% compared to labor costs.An IoT-based aquaculture monitoring system using Firebase can be effectively used as a technology for monitoring fish pond conditions in real-time and remotely for fish cultivators that contribute to providing an IoT-based aquaculture monitoring system that produces valid data,is precise,is easy to implement,and is a low-cost system.

Detection and Mapping of Violent Crime Hotspots in Southwestern Nigeria

The increasing rate of insecurity in Nigeria, especially the southwest requires a paradigm shift from popular approach to crime hotspots detection. This study employed geospatial technologies to integrate spatio-temporal crime, social media and field observation data from the communities in all the six states in the southwest to develop crime hotspots that can serve as preliminary information to assist in allocating resources for crime control and prevention. Historical crime data from January 1972 to April, 2021 were compiled and updated with rigorous field survey in September, 2021. The field data were encoded, input to the SPSS 17 and analyzed using descriptive statistics and multivariate analysis. A total 936 crime locations data were geolocated and exported to ArcGIS 10.5 for spatial mapping using point map operation and further imported to e-Spatial web-based and QGIS for the generation of hotspot map using heatmap tool. The results revealed that armed robbery, assassination and cultism were more pronounced in Lagos and Ogun States. Similarly, high incidences of farmers/herdsmen conflicts are observed in Oyo and Osun States. Increasing incidences of kidnapping are common in all the south-western states but very prominent in Ondo, Lagos and Oyo States. Most of the violent crime incidents took place along the highways, with forests being their hideouts. Violent crimes are dominantly caused by high rate of unemployment while farmer/herdsmen conflicts were majorly triggered by the scarcity of grazing fields and destruction of arable crops. The conflicts have resulted in the increasing cases of rape and disruption of social group, intake of hard drugs, cult-related activities, low income and revenue generation, and displacement of farmers and infrastructural damages. The study advocates regular retraining and equipping of security agents, establishment of cattle ranch, and installation of sophisticated IP Camera at the crime hotspots to assist in real-time crime monitoring and management.

营造科技新城的大学化中心区——探索一种创新街区的地域性空间模式及其设计方法

作为一种新兴、独特的空间类型和学术议题,创新时代科技新城的规划设计思想与方法值得深究。文章结合无锡市的实践,尝试建构一种科技新城中心区的空间发展模式—毯式大学。即传承江南园林空间基因的创新街区模式,总结其整体性的三种空间模式与重要的基质构造机理,以此在“去中心化”的创新文化与在地性的空间文化之间建立平衡,探索经由城市设计连接传统与现代、历史与未来的可能之路。

虚拟抠像技术在微课视频制作中的应用研究

将虛拟抠像技术应用在微课视频制作中既可以保证教学视频的质量,还可以让微课发展跟上互联网时代发展的步伐。虛拟抠图技术也叫虛拟演播室技术,其将摄像机拍摄的图像和计算机设计的三维虚拟背景空间进行有效融合,从而形成一种新的视频图像。

层次式图切分快速分割算法

图切分(Graph Cuts,GC)是近年来兴起的基于图论框架的图像分割方法,该理论的新颖之处在于它的全局最优性和结合多种知识的统一性。但当图像较大时运算非常耗时。该文提出了一种基于GC的层次式图像分割方法。先在低分辨率中用GC以较低的分割代价获取粗尺度的初始分割,再将结果轮廓映射回高分辨率图像中并构造出窄带,进而采用matting思想,在窄带内获取精确分割。实验结果表明,本文方法在确保分割结果准确性的同时,运算速度大幅度提高。