A study of the hypoechoic hypertrophic lesions and hypoechoic cancer lesions in hypertrophic prostate inner glands with transrectal color doppler ultrasonography

Objective: To observe the sonographic and hemodynamic features of hypoechoic hypertrophic lesions and hypoechoic cancer lesions in the hypertrophic prostate inner glands, in order to raise the accuracy of early diagnosis rate for prostate cancer. Methods: 31 cases of hypoechoic hypertrophic lesions and 18 cases of hypoechoic cancer lesions in the hypertrophic prostate inner glands were observed by transrectal ultrasonography and comparatively analyze the shape, edge and the systolic peak velocity (Vs) , resistance index (RI) and pulsatility index (PI) of the lesions. Results: In contrast with hypertrophic group, the cancer group presented irregular shape and unclear edge, and obviously higher Vs, RI and PI. Conclusion: The sonographic appearance and Vs. RI. PI have important value in distinguishing hypoechoic hypertrophic lesions and hypoechoic cancer lesions in the hypertrophic prostate inner glands.

Characters of normal prostate and prostate cancer lesions by transrectal contrast enhanced ultrasonography

Objective:The aim of the study was to observe the characters and differences of the inner and outer parts of prostate gland, the prostatic cancer lesions in inner and outer parts of prostate glands by transrectal contrast enhanced ultrasonography (TRCEUS) in order to provide valuable information for diagnosing of prostatic cancers. Methods: The ultrasound contrast agent was SonoVue (from Bracco Company, Italian). Instrument adopted Esaote Company Technos DU8 (transrectal ultrasonography). We observed the starting and ending times of transrectal contrast enhancement in the normal prostate inner gland group (16 cases), normal prostate outer gland group (16 cases), and the prostatic cancer lesions in inner gland group (8 cases) as well as in outer gland group (11 cases), respectively. Results: There was no significant difference in the starting time of the normal prostate glands between the inner gland and outer gland groups (P>0.05), likewise no significant difference between the cancer lesions in the inner gland and outer gland groups (P>0.05), but starting times of the cancer lesions in both groups were earlier than those of the normal prostate inner and outer glands groups (P<0.01). The ending time of enhancement was no significant difference among all groups (P>0.05). Conclusion: The earlier starting time of contrast enhancement in prostatic cancer lesions by TRCEUS has important value of distinguishing the cancer lesions from normal prostate glands. It is helpful to diagnose the prostatic cancer lesions.

Diagnostic Value between 1984 and 2018 of Transrectal Biopsy Guided by Ultrasonography after Radical Prostatectomy

Objectives—to determine correlation between GSs(Gleason scores)on needle biopsy and RP(radical prostatectomy),evaluating diagnostic tests on biopsy and RP within the last years,between 1984 and 2018.Method—analysis of 100 patients,diagnosed with PCa(prostate cancer)needle biopsy using 18-gauge needle,who underwent RP with lymphadenectomy and for which preoperative and postoperative GSs were available.GS group analysis used three categorization schemes for differentiation:mild,moderate and poor for the whole group and we determined SE(sensitivity),SP(specificity),PVPR(positive predictive value),negative predictive value and accuracy.Results—we found that 42%of the patients had no changes between GS on biopsy and prostatectomy,while 20%were overgraded and 38%undergraded by needle biopsy.Graduation of+1 point in GS(32%)or-1 point(17%)was the most common.Most patients were classified as moderately differentiated by biopsies(78 and 35%in scheme 1 and 2 or 3,respectively),while 43%of patients received an intermediate differentiation classification.Biopsy accuracy varied from 44 to 76%for the analysis of all three schemes.Conclusion—there are differences in correlation between GS on biopsy and on surgical specimen,and Gleason’s graduation also depends on the experience of the pathologist.We have shown that sextant biopsies using 18-gauge and a same group of pathologists showed acceptable concordance values(42%)between the GS on biopsy and prostatectomy.

Value of Real-Time Bedside Ultrasonography in the Etiologic Diagnosis of Acute Dyspnea

Objective: To explore the value of real-time bedside ultrasonography in the etiologic diagnosis of acute dyspnea. Methods: Sixty-two patients with acute dyspnea who were treated in our hospital from January 2016 to December 2020 were randomly selected and their clinical data were retrospectively analyzed. All patients were randomly divided into a control group for routine examinations (n = 31) and an observation group for real-time beside ultrasonography (n = 31). The costs of medical examinations, examination duration, and diagnostic results of severe pneumonia, acute cardiogenic pulmonary edema, pulmonary embolism, chronic obstructive pulmonary disease, and pneumothorax (including sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy) of the two groups of patients were compared and analyzed. Results: Compared with the control group, the observation group had significantly shorter examinations (P < 0.05). Although the cost of medical examinations of the observation group tended to be higher, the difference between groups was not significant (P > 0.05). Moreover, there were no significant differences in left ventricular ejection fraction, left ventricular end-diastolic diameter, or brain natriuretic peptide between the two groups (P > 0.05). Comparison of the etiologic diagnosis results between the two groups showed that the observation group had significantly higher diagnostic sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy for various causes compared with the control group (P < 0.05). Conclusion: Real-time bedside ultrasonography for the etiologic diagnosis of patients with acute dyspnea was quicker and had higher diagnostic accuracy;thus providing accurate guidance for the disease treatment, and having a higher promotional value in clinical practice compared with routine examinations.

前列腺癌诊断技术的研究进展

前列腺癌(prostate cancer,PCa)是全世界第二常见的男性恶性肿瘤疾病,近年来,我国PCa的发病率明显升高。目前针对PCa的诊断主要依赖于直肠指诊(digital rectal examination,DRE)、前列腺特异性抗原(prostate-specific antigen,PSA)检测、经直肠超声检查(transrectal ultrasonography,TRUS)、多参数磁共振成像(multi-parametric magnetic resonance imaging,mp-MRI),单一诊断方式存在局限性,经直肠超声引导下的穿刺活检是目前诊断前列腺癌的金标准。本文主要回顾了PCa领域中不同诊断技术的现有研究,并探讨了新的成像方式在未来的应用潜力,旨在为前列腺癌患者的早期诊断、临床治疗及改善预后提供更准确、全面的信息。

MRI、TRUS联合血清PSA对前列腺癌的诊断价值

目的研究磁共振成像(MRI)、经直肠超声(TRUS)结合血清前列腺特异性抗原(PSA)诊断前列腺癌诊断的应用价值。方法收集2020年1月—2023年1月前在武穴市第一人民医院检查的疑似前列腺癌患者140例,均给予MRI、TRUS检查,并进行血清PSA水平检测,以患者手术病理结果为金标准,观察单一MRI、TRUS、血清PSA及联合诊断时漏诊、误诊情况,进行一致性分析,计算各项单一诊断及联合诊断的诊断灵敏度、特异度、准确率。结果经手术病理结果证实为前列腺癌81例,非前列腺癌59例,前列腺癌患者血清PSA水平高于非前列腺癌患者(P<0.05);单一MRI、TRUS或PSA诊断前列腺癌与手术病理结果的一致性一般(Kappa=0.641、0.624、0.536,均P<0.001),联合诊断与手术病理结果的一致性较好(Kappa=0.906,P<0.001);联合诊断的灵敏度、特异度、准确率为高于单一MRI、TRUS、血清PSA及各诊断方式两两联合(P<α,α=0.007)。结论前列腺癌诊断中单一MRI、TRUS、血清PSA诊断均存在漏诊、误诊风险,联合诊断可弥补单一诊断的不足,提高前列腺癌患者的诊断准确率。

经阴囊及直肠超声联合血清AMH检测对梗阻性与非梗阻性无精子症的鉴别诊断价值

目的:探讨经阴囊及直肠超声联合血清抗米勒管激素(AMH)检测对无精子症的鉴别诊断价值。方法:选取2017年3月—2021年3月咸宁市第一人民医院收治的无精子症患者90例,均行阴囊及直肠超声检查、血清AMH检测,并根据睾丸活检结果将患者分为梗阻性无精子症(OA)组(n=38)和非梗阻性无精子症(NOA)组(n=52)。比较两组睾丸体积及超声征象、血清AMH水平,通过绘制受试者操作特征(ROC)曲线,分析经阴囊及直肠超声、血清AMH及联合诊断OA的效能。结果:超声结果显示,OA组睾丸体积≥12 mL、附睾及远端精道异常超声征象比例均显著高于NOA组,差异均有统计学意义(P<0.05)。OA组血清AMH水平为(8.43±2.57)ng/mL,明显高于NOA组的(5.58±1.72)ng/mL,差异有统计学意义(P<0.05)。ROC曲线显示,睾丸体积≥12 mL、附睾及远端精道异常超声征象(梗阻征象)、血清AMH、超声联合血清AMH诊断OA的曲线下面积(AUC)分别为0.788、0.793、0.881、0.964。结论:经阴囊及直肠超声联合血清AMH检测鉴别OA与NOA有较高的价值。

经直肠超声测量膀胱内前列腺突出程度对临床有意义前列腺癌检出率的价值

目的:探讨经直肠超声(TRUS)测量膀胱内前列腺突出程度(IPP)对临床有意义前列腺癌(CsPCa)检出率的价值。方法:回顾性分析2019年1月至2022年12月在东部战区总医院和江苏省人民医院经TRUS引导下行前列腺穿刺活检的患者128例。TRUS测量IPP大小并进行分级(0~3级),比较Gleason评分<7分(对照组)和Gleason评分≥7分(CsPCa组)患者临床病理及超声影像特征的差异及相关性。使用多元Logistic回归分析筛选与CsPCa检出率相关的因素。结果:单因素分析结果显示CsPCa组患者前列腺体积显著大于对照组[(51.3±12.1)ml vs(43.2±11.3)ml,P<0.05],PSAD显著低于对照组[(0.45±1.92)ng/ml vs(0.59±2.14)ng/ml,P<0.05]。CsPCa在IPP 3级的患者中占比低于IPP 0~2级(56.0%vs 85.4%、87.1%、80.6%),差异具有统计学意义(P<0.05)。Spearman相关分析结果表明,Gleason评分与前列腺体积呈正相关(r=0.612),与PSAD(r=-0.735)以及IPP分级(r=-0.619)呈负相关(P<0.05)。通过Logistic回归分析结果显示IPP 3级(OR 0.690,95%CI0.380~0.995,P=0.032)为CsPCa的独立保护因素。结论:CsPCa与前列腺IPP分级具有显著相关性,与IPP 0~2级患者相比,IPP 3级患者经TRUS引导下穿刺活检CsPCa检出率降低。因此,IPP分级增高时需警惕假阴性率的发生。

Value of transrectal ultrasonography for tumor node metastasis restaging in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy

Objective:To explore the value of transrectal ultrasonography(TRUS)for tumor node metastasis(TNM)restaging for patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy(neo-CRT).Methods:One hundred and forty-nine patients with locally advanced rectal cancer(cT3-4 or cN+)who underwent TRUS after neo-CRT were retrospectively reviewed.TRUS restaging was compared with the results of post-operative pathological TNM findings.Results:After neo-CRT,the accuracy of TRUS for diagnosing T-staging was 30.9%,with 60.4%(90/149)of cases overestimated.The sensitivity of TRUS for T-staging(T0 vs T1 vs T2 vs T3 vs T4)were 16.3%,0%,12.5%,42.6%and 75.0%,respectively.The accuracy of TRUS for diagnosing N-staging after neo-CRT was 81.2%,with the sensitivities of N0 and N+were 93.3%and 31.0%,respectively.After neo-CRT,27.5%(41/149)of patients achieved pathologically complete response(pCR).The sensitivity,specificity,positive predictive value and negative predictive values of TRUS for pCR were 17.1%,99.1%,87.5%and 75.9%,respectively.Conclusions:TRUS can be applied for restaging T4 and N0,and has potential for screening out patients with pCR in those with locally advanced rectal cancer after neo-CRT,although some stages are overestimated for T-staging and its sensitivity for predicting pCR is low.

顽固性血精病因和治疗初探

目的 :探讨顽固性血精的病因特点和影响治疗的因素 ,评价经直肠超声 (TRUS)引导下经会阴穿刺抽吸精囊液和灌注抗生素诊治顽固性血精的有效性。 方法 :入选 12例病人 ,平均年龄 (36 .4± 10 .8)岁 ,平均病程 (13.9± 6 .4 )个月。病人先行前列腺按摩 ,取得前列腺液 (EPS)并进行细菌培养。在TRUS引导下经会阴穿刺抽吸影像异常侧精囊液 (SVF)进行细菌培养和细胞学检查。根据EPS细菌培养和药敏试验结果选择抗生素 ,如细菌培养阴性则选择广谱抗生素 ,在TRUS引导下穿刺精囊进行灌注和冲洗。 1个月后复查时如血精未消失 ,则再次穿刺灌药。以后每 3个月随访 1次。 结果 :B超发现精囊异常影像位于左侧 4例 ,右侧 3例 ,双侧 2例 ,未见异常 3例。异常影像包括 :精囊或 和射精管扩张 7例 ;精囊壁增厚 3例 ;精囊壁钙化或精囊结石 3例 ;副中肾管 (M櫣ｌｌｅｒｉａｎｄｕｃｔ)囊肿1例。 7例SVF培养阳性 :耐甲氧西林金黄色葡萄球菌 (MRSA) 4例 ,耐甲氧西林凝固酶阴性葡萄球菌 (MRCNS)、大肠埃希菌、奇异变形杆菌各 1例。此 7例病人中 5例SVF和EPS细菌培养结果相同。在TRUS引导下经会阴穿刺精囊灌注抗生素并冲洗 ,7例灌注 1次 ,5例灌注 2次。随访 10例 ,平均 (16 .7± 5 .9)个月 ,6例未复发 ,4例仍反复发作。 结论

梗阻性无精子症经直肠B超声像表现及其临床意义

目的:探讨梗阻性无精子症经直肠B超的声像表现及其在梗阻定位诊断中的应用价值。方法:对248例临床诊断为梗阻性无精子症的男性患者行经直肠B超检查,观察前列腺、双侧精囊及射精管的声像表现。结果:本组病例前列腺体积平均13.2 ml。前列腺、双侧精囊及射精管形态正常111例。双侧精囊缺如39例,双侧精囊发育不全33例,单侧精囊发育不全、对侧精囊缺如23例,双侧精囊扩张28例,单侧精囊扩张14例。这42例精囊扩张者中射精管扩张18例、前列腺中线部位囊肿17例。结论:梗阻性无精子症的病变类型多样。经直肠B超可以清楚显示前列腺、精囊及射精管的形态与病变,对于判断梗阻性无精子症的病变类型及部位有一定的参考作用。

经直肠超声引导下精囊穿刺灌注治疗顽固性血精长期疗效观察

目的:评价经直肠超声(TRUS)引导下经会阴精囊穿刺灌注抗生素治疗顽固性血精的长期疗效。方法:入选12名患者,年龄(36.4±10.8)岁,病程(13.9±6.4)个月。取得前列腺按摩液(EPS)并进行细菌培养。在TRUS引导下经会阴穿刺抽吸影像异常侧精囊液(SVF)进行细菌培养。根据EPS细菌培养和药敏试验结果选择抗生素,细菌培养阴性者选择广谱抗生素,在TRUS引导下穿刺精囊进行灌洗和冲洗。1个月后复查时如血精未消失,则再次穿刺灌药。以后每3个月随访1次。结果:TRUS发现精囊和/或射精管异常影像者9例,包括精囊和/或射精管扩张7例;精囊壁增厚3例;精囊壁钙化或精囊结石3例;副中肾管囊肿1例。7例SVF培养阳性,其中耐甲氧西林金黄色葡萄球菌4例,耐甲氧西林凝固酶阴性葡萄球菌、大肠埃希菌、奇异变形杆菌各1例。随访10例,随访时间(31.4±5.7)个月,中位时间31.5个月。治疗后从未复发3例,曾经复发7例;末次随访时2例仍有持续发作,8例未发作。结论:TRUS引导下精囊穿刺灌注抗生素治疗顽固性血精有一定疗效。

对直肠内超声诊断用于直肠癌术前分期的探讨

目的评估直肠内超声诊断(transrectalultrasonography,TRUS)对直肠癌术前T分期的价值。方法收集原发性直肠癌45例。观察肿块大小、形态、回声、方位、浸润周径、深度及邻近组织脏器受累。结果45例中,TRUS检出42例;超声分期(uT)与病理分期(pT)相符32例,符合率76%。TRUS所测肿瘤长、短径与pT无明显关系(P=0.083、0.499),而侵犯周径则与pT有关(P=0.015)。结论对于多数直肠癌患者,TRUS是其T分期的有效手段;难以判断肿瘤浸润深度时,结合侵犯周径可提高分期准确性。

直肠超声引导下经会阴与经直肠前列腺穿刺活检术诊断前列腺癌的临床价值比较

目的比较直肠超声引导下经会阴与经直肠前列腺穿刺活检术诊断前列腺癌的临床价值。方法回顾分析本院行直肠超声引导下经会阴前列腺穿刺活检术的175例患者与经直肠前列腺穿刺活检术的137例患者资料,比较两组患者的术前资料、前列腺癌阳性检出率及安全性。结果两组患者的血清PSA、前列腺结节检出率及前列腺体积无明显差别,经会阴穿刺患者的前列腺癌阳性检出率为41.14%,并发疼痛、发热、血尿及尿潴留的患者分别占9.14%、3.43%、6.86%和5.71%,无患者发生血便。经直肠穿刺患者的前列腺癌阳性检出率为39.42%,并发疼痛、发热、血尿、尿潴留及血便的患者分别为8.03%、9.49%、8.03%、5.84%和5.11%;两种方法比较,经会阴穿刺术后患者发热及血便的发生率明显低于经直肠穿刺的患者,而前列腺癌阳性检出率、术后疼痛、血尿和尿潴留的发生率无明显差异。结论经直肠超声引导下的经会阴穿刺和经直肠穿刺前列腺活检术都是有效的活检方法。应根据患者直肠指检是否扪及肿块、TRUS是否发现占位及患者身体状况来选择穿刺方法。有感染倾向的患者应选择经会阴穿刺活检。

经会阴及经直肠前列腺穿刺活检术的临床应用分析

目的:比较经直肠及经会阴两种前列腺穿刺活检术的阳性率及并发症。方法:回顾性分析2009年1月至2014年1月间156例前列腺穿刺活检病例,其中经直肠径路97例,经会阴径路59例。结果:经直肠径路组穿刺阳性率为48.4%,经会阴径路组为44.1%。根据不同的PSA水平分层,两种径路穿刺活检的阳性率无显著性差异(P>0.05)。穿刺后经直肠径路组与经会阴径路组血尿发生率分别为54.6%、42.4%,尿频尿急尿痛发生率分别为17.5%、22.0%,排尿困难发生率分别为9.3%、6.8%,急性尿潴留发生率分别为7.2%、6.8%,上述并发症发生率在两组间差异无统计学意义(P>0.05);发热发生率分别为15.5%、3.4%,血便发生率分别为50.5%、3.4%,经直肠径路组要显著高于经会阴径路组(P<0.05及P<0.01);会阴肿胀发生率分别为3.1%、13.6%,经会阴径路组显著性增高(P<0.05)。结论:超声引导下经直肠和经会阴前列腺穿刺活检术都是诊断前列腺癌的有效方法。两种方式的穿刺阳性率无显著性差异,但并发症发生率各有特点,具体方式选择应根据患者情况决定。

经直肠三维超声检查和前列腺特异抗原在前列腺癌穿刺活检中的作用

目的 分析经直肠超声 (TRUS)和前列腺特异抗原 (PSA)在前列腺癌穿刺活检中的作用 ,提出各种穿刺方式适用的条件 ,以求在减少穿刺并发症的前提下获得较高的阳性结果。方法 我院 2 0 0 0年 4月至 2 0 0 1年 4月行前列腺穿刺病例5 4例 ,术前因为超声检查发现前列腺异常病灶或超声检查未发现前列腺异常病灶但直肠指检前列腺较硬而均经血清PSA测定异常 ,经TRUS引导行病灶活检或系统 6点穿刺活检。结果 3 1人PSA≥ 2 0ng/ml,穿刺病理阳性 2 5例 ,前列腺癌的检出率为 80 .6% ,其中TRUS发现可疑病灶 (TRUS +) 2 1例均证实为癌。 2 3人PSA <2 0ng/ml,穿刺病理阳性 2例 ,前列腺癌的检出率为 8.7%。TRUS( +) 3例 ,仅 1例证实为癌。此两组病人前列腺癌的检出率差异明显 (P <0 .0 1)。结论 当超声发现高度怀疑病灶同时PSA≥ 2 0ng/ml,建议病灶穿刺 ;超声检查阴性而PSA≥ 2 0ng/ml且前列腺体积明显增大者宜行 13点TRUS引导活检 ;若PSA <2 0ng/ml则首次活检时包扩病灶在内的 6点系统穿刺较为可取。

梗阻性无精子症的外科治疗(附56例报告)

目的:探讨梗阻性无精子症的诊断和外科治疗方法。方法:分析2004年10月至2008年11月间收治的56例梗阻性无精子症患者的临床资料,其中43例为射精管梗阻性无精子症,13例疑为附睾水平梗阻性无精子症。常规精液分析、精浆果糖和中性α葡糖苷酶测定以及经直肠超声检查(TRUS)对其进行诊断,必要时行输精管造影检查。43例为射精管梗阻性无精子症使用经尿道射精管切开术(TURED)治疗,13例疑为附睾水平梗阻性无精子症行阴囊探查术,对其中11例确定为附睾水平梗阻行双侧或单侧附睾输精管端侧吻合术,术后随访其疗效。结果:所有患者均完成手术,术后随访3～51个月。43例射精管梗阻性无精子症TURED术后,36例(83.7%)精液检查有不同程度的改善,11例(25.6%)妻子妊娠。11例附睾水平梗阻性无精子症行输精管附睾吻合术后,6例(54.5%)精液检查检出活精子,3例(27.3%)妻子妊娠。结论:精液分析、精浆果糖和中性α葡糖苷酶测定,TRUS和输精管造影是诊断梗阻性无精子症的主要方式。TURED和输精管附睾吻合术分别是治疗射精管梗阻性无精子症和附睾水平梗阻性无精子症的有效方法。

经直肠彩色多普勒超声膀胱肿瘤显像的临床价值

目的 探讨经直肠腔内彩色多普勒超声显像对膀胱肿瘤的临床价值。方法 对 3 6例膀胱肿瘤患者先经腹壁再经直肠进行彩色多普勒超声检查 ,对两种方法的显示率进行比较 ,记录血流参数 ,进行统计学分析。结果 经腹壁和经直肠彩色多普勒显像肿瘤显示率分别为 61%和 97% ,有显著差异 (P <0 .0 5 )。最大血流速度Vmax和最小血流速度Vmin在较小的肿瘤低 ,较大肿瘤高。阻力指数RI在较小的肿瘤高 ,较大肿瘤低 ,但没有统计学差异 (P >0 .0 5 )。结论 膀胱肿瘤彩色多普勒超声显像经直肠检查方法优于经腹壁方法 ,特别是小于 2 .

经直肠超声检查在男性梗阻性无精子症病因筛查中的作用(附695例病例分析)

目的:探讨经直肠超声(TRUS)在男性梗阻性无精子症病因筛查中的作用。方法:回顾性分析我院2007年1月至2009年5月695例男性梗阻性无精子症患者的TRUS的病因诊断结果。结果:695例梗阻性无精子症患者中,TRUS检查发现病变以射精管病变(29.2%)、精囊腺病变(25.4%)以及前列腺中线囊肿病变(18.5%)为主。TRUS检查共发现射精管扩张203例;精囊腺病变177例,其中先天性精囊腺缺如或者发育不全108例,精囊腺扩张51例;另外,TRUS诊断发现前列腺中线囊肿128例,其中75例(58.5%)射精管囊肿,39例(30.5%)苗勒管囊肿。34例患者的梗阻性无精子症可能由于钙化性疾病导致。而153例患者(22.0%)TRUS检查未见明显异常。TRUS在本组梗阻性无精子症患者中,78.0%可以发现比较明确的病因。结论:TRUS可以比较清晰地观察射精管以及精囊腺等结构异常,可以为远端输精系统梗阻的病因诊断提供重要的参考信息。

前列腺癌经直肠超声图像特征与其危险度的关系研究

目的探讨前列腺癌（PCa）经直肠超声（TRUS）图像特征与其危险度的关系。方法回顾性选取2013年5月—2015年3月同济大学附属第十人民医院收治的符合纳入标准的PCa患者102例为研究对象,患者均经穿刺活检后病理确诊,均行TRUS检查及MRI检查,根据前列腺特异抗原（PSA）、穿刺病理Gleason评分〈7分或临床分期分为PCa低危、中危、高危。观察不同TRUS图像特征（包括前列腺两侧对称性、包膜完整性、内外腺分界清晰度、有无前列腺结节,有前列腺结节者观察结节大小、结节边界、结节回声及结节血流）与PCa危险度的关系。结果102例PCa患者中,低危19例（18.6%）,中危29例（28.4%）,高危54例（53.0%）。前列腺两侧不对称、包膜不完整、内外腺分界不清晰的患者PCa危险度高于两侧对称、包膜完整、内外腺分界清晰的患者（P〈0.05）。有无结节患者PCa危险度比较,差异无统计学意义（P〉0.05）。56例有前列腺结节的PCa患者中,低危6例,中危18例,高危32例。结节≥10 mm患者PCa危险度高于结节〈10 mm,结节血流Ⅱ~Ⅲ级的患者PCa危险度高于结节血流0-Ⅰ级（P〈0.05）;不同结节边界清晰度、结节回声患者PCa危险度比较,差异无统计学意义（P〉0.05）。结论TRUS图像特征中前列腺两侧对称性、包膜完整性、内外腺分界清晰度、结节大小及结节血流可以评估PCa的危险度,因此建议将TRUS检查结果作为临床治疗的参考。