Equivalent source layer （ESL） imaging is an important kind of high-resolution electro- encephalogram （EEG） imaging. It consists of two categories： equivalent dipole layer （EDL） and equivalent charge layer （ECL...Equivalent source layer （ESL） imaging is an important kind of high-resolution electro- encephalogram （EEG） imaging. It consists of two categories： equivalent dipole layer （EDL） and equivalent charge layer （ECL）. Both of them are assumed to be located on or near the cortical surface and have been proposed as high-resolution imaging modalities or as intermediate steps to estimate the epicortical potential. Here, EDL and ECL based on a realistic head model are presented, both simulations and real data experiment are done to compare these two models. The results show that ECL can provide higher spatial resolution about source location than EDL does.展开更多
Invasive techniques are becoming increasingly important in the presurgical evaluation of epilepsy.Adopting the electrophysiological source imaging(ESI)of interictal scalp electroencephalography(EEG)to localize the epi...Invasive techniques are becoming increasingly important in the presurgical evaluation of epilepsy.Adopting the electrophysiological source imaging(ESI)of interictal scalp electroencephalography(EEG)to localize the epileptogenic zone remains a challenge.The accuracy of the preoperative localization of the epileptogenic zone is key to curing epilepsy.The T1 MRI and the boundary element method were used to build the realistic head model.To solve the inverse problem,the distributed inverse solution and equivalent current dipole(ECD)methods were employed to locate the epileptogenic zone.Furthermore,a combination of inverse solution algorithms and Granger causality connectivity measures was evaluated.The ECD method exhibited excellent focalization in lateralization and localization,achieving a coincidence rate of 99.02%(p<0.05)with the stereo electroencephalogram.The combination of ECD and the directed transfer function led to excellent matching between the information flow obtained from intracranial and scalp EEG recordings.The ECD inverse solution method showed the highest performance and could extract the discharge information at the cortex level from noninvasive low-density EEG data.Thus,the accurate preoperative localization of the epileptogenic zone could reduce the number of intracranial electrode implantations required.展开更多
文摘Equivalent source layer （ESL） imaging is an important kind of high-resolution electro- encephalogram （EEG） imaging. It consists of two categories： equivalent dipole layer （EDL） and equivalent charge layer （ECL）. Both of them are assumed to be located on or near the cortical surface and have been proposed as high-resolution imaging modalities or as intermediate steps to estimate the epicortical potential. Here, EDL and ECL based on a realistic head model are presented, both simulations and real data experiment are done to compare these two models. The results show that ECL can provide higher spatial resolution about source location than EDL does.
基金Supported by the National Key R&D Program of China(2022YFC2402203)the Key R&D Program of Hebei(21372002D)。
文摘Invasive techniques are becoming increasingly important in the presurgical evaluation of epilepsy.Adopting the electrophysiological source imaging(ESI)of interictal scalp electroencephalography(EEG)to localize the epileptogenic zone remains a challenge.The accuracy of the preoperative localization of the epileptogenic zone is key to curing epilepsy.The T1 MRI and the boundary element method were used to build the realistic head model.To solve the inverse problem,the distributed inverse solution and equivalent current dipole(ECD)methods were employed to locate the epileptogenic zone.Furthermore,a combination of inverse solution algorithms and Granger causality connectivity measures was evaluated.The ECD method exhibited excellent focalization in lateralization and localization,achieving a coincidence rate of 99.02%(p<0.05)with the stereo electroencephalogram.The combination of ECD and the directed transfer function led to excellent matching between the information flow obtained from intracranial and scalp EEG recordings.The ECD inverse solution method showed the highest performance and could extract the discharge information at the cortex level from noninvasive low-density EEG data.Thus,the accurate preoperative localization of the epileptogenic zone could reduce the number of intracranial electrode implantations required.
