Objective To evaluate the sensitivity and specificity of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) measurements in diagnosing abdominal visceral obesity. Methods BMI, WC, and WHR wer...Objective To evaluate the sensitivity and specificity of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) measurements in diagnosing abdominal visceral obesity. Methods BMI, WC, and WHR were assessed in 690 Chinese adults (305 men and 385 women) and compared with magnetic resonance imaging (MRI) measurements of abdominal visceral adipose tissue (VA). Receiver operating characteristic (ROC) curves were generated and used to determine the threshold point for each anthropometric parameter. Results 1) MRI showed that 61.7% of overweight/obese individuals (BMI≥25 kg/m2) and 14.2% of normal weight (BMI<25 kg/m2) individuals had abdominal visceral obesity (VA≥100 cm2). 2) VA was positively correlated with each anthropometric variable, of which WC showed the highest correlation (r=0.73-0.77, P<0.001). 3) The best cut-off points for assessing abdominal visceral obesity were as followed: BMI of 26 kg/m2, WC of 90 cm, and WHR of 0.93, with WC being the most sensitive and specific factor. 4) Among subjects with BMI≥28 kg/m2 or WC≥95 cm, 95% of men and 90% of women appeared to have abdominal visceral obesity. Conclusion Measurements of BMI, WC, and WHR can be used in the prediction of abdominal visceral obesity, of which WC was the one with better accuracy.展开更多
Background： To combine dinicopathological characteristics associated with lymph node metastasis for submucosal gastric cancer into a nomogram. Methods： We retrospectively analyzed 262 patients with submucosal gastri...Background： To combine dinicopathological characteristics associated with lymph node metastasis for submucosal gastric cancer into a nomogram. Methods： We retrospectively analyzed 262 patients with submucosal gastric cancer who underwent D2 gastrectomy between 1996 and 2012. The relationship between lymph node metastasis and clinicopathological features was statistically analyzed. With multivariate logistic regression analysis, we made a nomogram to predict the possibility of lymph node metastasis. Receiver operating characteristic （ROC） analysis was also performed to assess the predictive value of the model. Discrimination and calibration were performed using internal validation. Results： A total number of 48 （18.3%） patients with submucosal gastric cancer have pathologically lymph node metastasis. For submucosal gastric carcinoma, lymph node metastasis was associated with age, tumor location, macroscopic type, size, differentiation, histology, the existence of ulcer and lymphovascular invasion in univariate analysis （all P〈0.05）. The multivariate logistic old, macroscopic type III or mixed, undifferentiated type, regression analysis identified that age _〈50 years and presence of lymphovascular invasion were independent risk factors of lymph node metastasis in submucosal gastric cancer （all P〈0.05）. We constructed a predicting nomogram with all these factors for lymph node metastasis in submucosal gastric cancer with good discrimination [area under the curve （AUC） =0.844]. Internal validation demonstrated a good discrimination power that the actual probability corresponds closely with the predicted probability. Conclusions： We developed a nomogram to predict the rate of lymph node metastasis for submucosal gastric cancer. With good discrimination and internal validation, the nomogram improved individualized predictions for assisting clinicians to make appropriated treatment decision for submucosal gastric cancer patients.展开更多
本文使用中国家庭动态跟踪调查(CFPS)数据,基于代理工具测试模型(Proxy means testing,PMT)并结合ROC曲线方法(Receiver Operating Characteristics)研究低保的反贫困瞄准问题.结果显示:城市单个贫困指数以卫生间类型、电脑拥有情况来...本文使用中国家庭动态跟踪调查(CFPS)数据,基于代理工具测试模型(Proxy means testing,PMT)并结合ROC曲线方法(Receiver Operating Characteristics)研究低保的反贫困瞄准问题.结果显示:城市单个贫困指数以卫生间类型、电脑拥有情况来衡量较为有效,农村单个贫困指数则以户主年龄、冰箱拥有情况来衡量较为有效.更改贫困概率门槛值会影响公共预算转移支付贫困瞄准结果,对于一个较低的贫困概率门槛值,其对应的覆盖率(公共预算转移支付覆盖贫困人口)和漏损率(非贫困人口被纳入公共预算转移支付)都比较高.当政策制定者把对覆盖贫困人口和排除非贫困人口的目标赋予同等权重时,城乡贫困概率门槛值约为0.5左右.当贫困率较低且使用与贫困率相同的瞄准率时,基于PMT模型的贫困瞄准较差.在贫困率给定的条件下,随着受益比率(包含率)的增加,贫困瞄准的精确性在提高.使用全覆盖所需预算的百分比下降时,覆盖率和漏损率也都呈现下降态势,贫困率逐渐上升,预算中做覆盖之用的比例上升,而预算中漏损部分的比例下降.贫困线的变动会影响覆盖率、漏损率.展开更多
文摘Objective To evaluate the sensitivity and specificity of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) measurements in diagnosing abdominal visceral obesity. Methods BMI, WC, and WHR were assessed in 690 Chinese adults (305 men and 385 women) and compared with magnetic resonance imaging (MRI) measurements of abdominal visceral adipose tissue (VA). Receiver operating characteristic (ROC) curves were generated and used to determine the threshold point for each anthropometric parameter. Results 1) MRI showed that 61.7% of overweight/obese individuals (BMI≥25 kg/m2) and 14.2% of normal weight (BMI<25 kg/m2) individuals had abdominal visceral obesity (VA≥100 cm2). 2) VA was positively correlated with each anthropometric variable, of which WC showed the highest correlation (r=0.73-0.77, P<0.001). 3) The best cut-off points for assessing abdominal visceral obesity were as followed: BMI of 26 kg/m2, WC of 90 cm, and WHR of 0.93, with WC being the most sensitive and specific factor. 4) Among subjects with BMI≥28 kg/m2 or WC≥95 cm, 95% of men and 90% of women appeared to have abdominal visceral obesity. Conclusion Measurements of BMI, WC, and WHR can be used in the prediction of abdominal visceral obesity, of which WC was the one with better accuracy.
文摘Background： To combine dinicopathological characteristics associated with lymph node metastasis for submucosal gastric cancer into a nomogram. Methods： We retrospectively analyzed 262 patients with submucosal gastric cancer who underwent D2 gastrectomy between 1996 and 2012. The relationship between lymph node metastasis and clinicopathological features was statistically analyzed. With multivariate logistic regression analysis, we made a nomogram to predict the possibility of lymph node metastasis. Receiver operating characteristic （ROC） analysis was also performed to assess the predictive value of the model. Discrimination and calibration were performed using internal validation. Results： A total number of 48 （18.3%） patients with submucosal gastric cancer have pathologically lymph node metastasis. For submucosal gastric carcinoma, lymph node metastasis was associated with age, tumor location, macroscopic type, size, differentiation, histology, the existence of ulcer and lymphovascular invasion in univariate analysis （all P〈0.05）. The multivariate logistic old, macroscopic type III or mixed, undifferentiated type, regression analysis identified that age _〈50 years and presence of lymphovascular invasion were independent risk factors of lymph node metastasis in submucosal gastric cancer （all P〈0.05）. We constructed a predicting nomogram with all these factors for lymph node metastasis in submucosal gastric cancer with good discrimination [area under the curve （AUC） =0.844]. Internal validation demonstrated a good discrimination power that the actual probability corresponds closely with the predicted probability. Conclusions： We developed a nomogram to predict the rate of lymph node metastasis for submucosal gastric cancer. With good discrimination and internal validation, the nomogram improved individualized predictions for assisting clinicians to make appropriated treatment decision for submucosal gastric cancer patients.
文摘本文使用中国家庭动态跟踪调查(CFPS)数据,基于代理工具测试模型(Proxy means testing,PMT)并结合ROC曲线方法(Receiver Operating Characteristics)研究低保的反贫困瞄准问题.结果显示:城市单个贫困指数以卫生间类型、电脑拥有情况来衡量较为有效,农村单个贫困指数则以户主年龄、冰箱拥有情况来衡量较为有效.更改贫困概率门槛值会影响公共预算转移支付贫困瞄准结果,对于一个较低的贫困概率门槛值,其对应的覆盖率(公共预算转移支付覆盖贫困人口)和漏损率(非贫困人口被纳入公共预算转移支付)都比较高.当政策制定者把对覆盖贫困人口和排除非贫困人口的目标赋予同等权重时,城乡贫困概率门槛值约为0.5左右.当贫困率较低且使用与贫困率相同的瞄准率时,基于PMT模型的贫困瞄准较差.在贫困率给定的条件下,随着受益比率(包含率)的增加,贫困瞄准的精确性在提高.使用全覆盖所需预算的百分比下降时,覆盖率和漏损率也都呈现下降态势,贫困率逐渐上升,预算中做覆盖之用的比例上升,而预算中漏损部分的比例下降.贫困线的变动会影响覆盖率、漏损率.
