Objective: To evaluate the clinicopathological characteristics of rectal cancer diagnosed as adenoma in biopsy. Methods: 50 rectal cancer cases diagnosed as adenoma in biopsy were analyzed retrospectively in this stud...Objective: To evaluate the clinicopathological characteristics of rectal cancer diagnosed as adenoma in biopsy. Methods: 50 rectal cancer cases diagnosed as adenoma in biopsy were analyzed retrospectively in this study by comparing the biopsy and postoperative pathology. Results: Among these 50 patients, biopsy pathology showed 26% (13/50) adenoma with mild dysplasia, 30% (15/50) adenoma with moderate dysplasia, and 44% (22/50) adenoma with severe dysplasia. In 8 cases, the adenomas were smaller than 2cm. On postoperatively surgical pathology, only 10 cases were carcinoma-in-situ, while 40 cases were invasive cancer. Conclusion: Special emphasis should be taken to biopsy-negative rectal adenomas and those smaller than 2cm.展开更多
Thanks to major advances in the field of surgical techniques and neoadjuvant chemoradiation therapy,along with more accurate pre-operative staging tools and the widespread introduction of population-based screening pr...Thanks to major advances in the field of surgical techniques and neoadjuvant chemoradiation therapy,along with more accurate pre-operative staging tools and the widespread introduction of population-based screening programs,treatment of rectal cancer has been evolving over the past few decades,moving towards a more tailored approach.This has brought a shift in the treatment algorithm of benign rectal lesions and selected early rectal cancers,for which today transanal endoscopic microsurgery(TEM)is accepted as an effective alternative to abdominal surgery.In 2013,topics of controversy are the role of TEM in the treatment of more advanced rectal cancers,in cases of complete pathological response after chemoradiation therapy and the role of TEM as a platform for single-port surgery and NOTES.This article reviews the current indications for TEM and the future perspectives of this approach in the treatment of rectal tumors.展开更多
文摘Objective: To evaluate the clinicopathological characteristics of rectal cancer diagnosed as adenoma in biopsy. Methods: 50 rectal cancer cases diagnosed as adenoma in biopsy were analyzed retrospectively in this study by comparing the biopsy and postoperative pathology. Results: Among these 50 patients, biopsy pathology showed 26% (13/50) adenoma with mild dysplasia, 30% (15/50) adenoma with moderate dysplasia, and 44% (22/50) adenoma with severe dysplasia. In 8 cases, the adenomas were smaller than 2cm. On postoperatively surgical pathology, only 10 cases were carcinoma-in-situ, while 40 cases were invasive cancer. Conclusion: Special emphasis should be taken to biopsy-negative rectal adenomas and those smaller than 2cm.
文摘Thanks to major advances in the field of surgical techniques and neoadjuvant chemoradiation therapy,along with more accurate pre-operative staging tools and the widespread introduction of population-based screening programs,treatment of rectal cancer has been evolving over the past few decades,moving towards a more tailored approach.This has brought a shift in the treatment algorithm of benign rectal lesions and selected early rectal cancers,for which today transanal endoscopic microsurgery(TEM)is accepted as an effective alternative to abdominal surgery.In 2013,topics of controversy are the role of TEM in the treatment of more advanced rectal cancers,in cases of complete pathological response after chemoradiation therapy and the role of TEM as a platform for single-port surgery and NOTES.This article reviews the current indications for TEM and the future perspectives of this approach in the treatment of rectal tumors.
