The authors reported the case of a 35-year-old woman with an unusual huge recurrent meningioma in the left cerebral hemisphere confirmed by the pathological examination.This patient's clinical presentation was ver...The authors reported the case of a 35-year-old woman with an unusual huge recurrent meningioma in the left cerebral hemisphere confirmed by the pathological examination.This patient's clinical presentation was very unusual.Brain magnetic resonance imaging(MRI) demonstrated a huge tumor in the left frontal region.The extracranial surface dimensions of the mass were 12cm craniocaudal × 11cm transverse × 9cm anteroposterior;and the intracranial dimensions were 9cm craniocaudal × 7cm transverse × 10cm anteroposterior respectively.The patient underwent left frontal recurrent meningioma resection by microsurgery,with total tumor resection.Following which the patient was discharged in a stable condition.To the best of the authors' knowledge,such an unusual huge recurrent meningioma has not been reported.The authors reviewed the literatures with reference to recurrent meningioma,analyzed the unusual imaging appearances of this patient,and explored the mechanism underlying the huge volume formation.The fundamental principle to reducing or completely avoiding meningioma recurrence is to achieve total tumour resection.Recurrent meningiomas are also amenable to surgery.展开更多
Background Atypical meningioma is one of the rare subtypes of meningioma, which is lacking of optimal consensus on treatment strategies. This study aimed to investigate the radical treatment strategies to improve the ...Background Atypical meningioma is one of the rare subtypes of meningioma, which is lacking of optimal consensus on treatment strategies. This study aimed to investigate the radical treatment strategies to improve the long-term outcome of recurrent atypical meningiomas. Methods The prognostic factors including the age and gender of patients; the location, histology, recurrence pattern and mitotic cell rate of the tumors; and the resection extents, surgical strategies and adjuvant therapies of 15 cases of recurrent atypical meningiomas were analyzed retrospectively. Results The age and gender of patients were not associated with tumor recurrence. However, high recurrence rates and poor prognosis for atypical meningiomas were associated with the high mitotic cell rate, failure to achieve Simpson grade Ⅰ-Ⅱ resection, and without the dura and bone flap replacement intraoperatively. Post-operative radiotherapy improved the outcomes of tumors in patients after the second surgery. Conclusion Radical treatment strategies such as dura and bone flap replacements and radiotherapy should be considered in patients diagnosed with atypical meningiomas.展开更多
文摘The authors reported the case of a 35-year-old woman with an unusual huge recurrent meningioma in the left cerebral hemisphere confirmed by the pathological examination.This patient's clinical presentation was very unusual.Brain magnetic resonance imaging(MRI) demonstrated a huge tumor in the left frontal region.The extracranial surface dimensions of the mass were 12cm craniocaudal × 11cm transverse × 9cm anteroposterior;and the intracranial dimensions were 9cm craniocaudal × 7cm transverse × 10cm anteroposterior respectively.The patient underwent left frontal recurrent meningioma resection by microsurgery,with total tumor resection.Following which the patient was discharged in a stable condition.To the best of the authors' knowledge,such an unusual huge recurrent meningioma has not been reported.The authors reviewed the literatures with reference to recurrent meningioma,analyzed the unusual imaging appearances of this patient,and explored the mechanism underlying the huge volume formation.The fundamental principle to reducing or completely avoiding meningioma recurrence is to achieve total tumour resection.Recurrent meningiomas are also amenable to surgery.
文摘Background Atypical meningioma is one of the rare subtypes of meningioma, which is lacking of optimal consensus on treatment strategies. This study aimed to investigate the radical treatment strategies to improve the long-term outcome of recurrent atypical meningiomas. Methods The prognostic factors including the age and gender of patients; the location, histology, recurrence pattern and mitotic cell rate of the tumors; and the resection extents, surgical strategies and adjuvant therapies of 15 cases of recurrent atypical meningiomas were analyzed retrospectively. Results The age and gender of patients were not associated with tumor recurrence. However, high recurrence rates and poor prognosis for atypical meningiomas were associated with the high mitotic cell rate, failure to achieve Simpson grade Ⅰ-Ⅱ resection, and without the dura and bone flap replacement intraoperatively. Post-operative radiotherapy improved the outcomes of tumors in patients after the second surgery. Conclusion Radical treatment strategies such as dura and bone flap replacements and radiotherapy should be considered in patients diagnosed with atypical meningiomas.
