Dryness-wetness change and regional differentiation of flood-drought disasters in Guangdong during 1480-1940AD

Based on the historical records of the drought and flood disasters during 1480-1940AD, this paper reconstructs the sequences of wetness index （WI） and drought and flood disasters. We find a good identical relationship between the fluctuation of WI sequence and the δ^18O record of the GISP2 ice core in Greenland, which shows an apparent monsoonal disposal pattern of moisture and temperature. By applying the Morlet Wavelet Transform Method to deal with the data, several apparent periodicities, such as 7-8a, 11-15a, 20-23a and ca 50a, are revealed, among which some can be attributed to the solar forcing. Based on results of Cluster Analysis of dry-wet changes, we resume the regional differentiation pattern of flood-drought disasters all over Guangdong during different climatic intervals in the LIA and, find the western and northern parts of Guangdong have undergone drastic changes in drought-flood regional differentiation, but the eastern part is relatively stable, and the area of the Pearl River Delta shows stable condition of more flood disasters.

Regional Differentiation Regularity and Influencing Factors of Population Change in the Qinghai-Tibet Plateau, China

The Qinghai-Tibet Plateau(QTP) is the most unique region of human-land relations, and its main factor is population. By building a population and space dataset of the QTP at the township level from 1982 to 2017, this paper presents the pattern evolvement and regional distribution characteristics of township-level population in the QTP in detail for the first time. By using Geodetector method to analyze the influencing factors of township-level population change in the QTP, this paper provides scientific foundations for studying the Third Pole, ecological environment protection of the QTP, and human-land relations. The conclusions are as follows:1) The population spatial distribution is not balanced at the township level, presents the regional differentiation characteristics of ‘dense in southeast and sparse in northwest’ along the ‘Qilian-Jilong Line’, and demonstrates the phenomenon of population center of gravity moving to the hinterland of the plateau at an accelerated speed;2) The township-level population develops in a decentralized trend in general, and the cold-and hot-spot distribution of population has prominent spatial distribution characteristics. The population hot spots are concentrated in the surrounding areas of Xining, Golmud, Hotan and Lijiang;3) The population of the QTP is increasing, and the inter-annual change of township population has a relatively stable regional regularity;4) The level of per capita income is the leading factor in the change of township population, and its effect intensity is increasing continuously. The relative effect intensity of urbanization level and location conditions on population change has decreased significantly after 2000. The adaptability of living environment,such as topography and climate, has little influence on population change.

REGIONAL DIFFERENTIATION OF CRITICAL CONCENTRATION OF ARSENIC(As) AND CADMIUM (Cd) IN MAIN SOIL TYPES OF CHINA

Studies of critical concentration distribution features of polluted elements of Cd and As in main soil types of China, such as laterite, crimson soil, purplish soil, yellow brown soil, brunisolic soil, black soil, cinnamon soil and sierozem revealed that soil types vary in different zones, so do their critical concentrations.The critical concentration has a zonal differentiation with the distribution of soil types from south to north, and from east to west. The critical concentration of Cd increases from south to north (yellow brown soil,brunisolic soil and cinnamon soil),and from east to west (black soil and sierozem). This coincides With changes of climate zones and soil zones. On the contrary, the critical concentration of Asdecreases from south to north and from east to west.

GEOMORPHOLOGICAL CHARACTERISTICS AND REGIONAL DIFFERENTIATION OF LANDSCAPE OF NORTH SHAANXI

Northern Shaanxi is located on the Erdos syncline, a subdivision of North China Shield. The loess landforms are the main landform types, additionally, there are low rocky mountains and hills, valleys and eolian landforms. Changes of techonic bases and of water-heat conditions in the region cause obvious regional differentiations of the landcape. From south to north,accompanying with uprising of the relief and decrease of mean annual temperature and precipitation, the types of landforms, degree of dissection,vegetation cover-degree and intensity of soil and water loesses show clearly latitudinal zonation.

Regional Environmental Differentiation in China Sincethe Mid-Pleistocene Inferred from Lake Recordsand Its Relation with East Asian Monsoons

Abstract: Comparative study of long lake records in different regions in China can provide some significant information about the regional differentiation of the environment and Asian monsoon activities. However, intensively studied lacustrine cores with a span of a few hundred thousand years are very rare in China. The available examples are only three long cores from the Zoigê basin in the eastern Qinghai-Tibet plateau, the Qaidam basin in the northern Qinghai-Tibet plateau and the Dianchi basin in the Yunnan plateau respectively. The results show that the regional environmental differentiation since the Mid-Pleistocene involved three stages, i.e. 780–480, 480–160, 160–0 ka B.P. In each of the three stages different regions of China had their own distinctive environmental characteristics, indicating that the uplift of the Qinghai-Tibet plateau played a major role in the environmental differentiation process.

Regional differentiation of ecological conservation and its zonal suitability at the county level in China

China＇s investments, financial incentives and deductions in terms of ecological conservation are based at the county level. Therefore, the monitoring and assessment of the effects of ecological conservation at the county level is important to provide a scientific basis for the assessment of the ecological and environmental quality at the county scale. This paper quantitatively estimated the dynamics of high-quality ecosystems and vegetation coverage over the past 15 years, and their relationships with the number of ecological conservation programs at the county level were analyzed. Then, the effects of ecological conservation measures on ecological changes at the county level and their regional suitability were as- sessed and discussed. The results showed that counties with a percentage of high-quality ecosystems greater than 50% were primarily distributed in northeastern China, southern subtropical China and the southeastern Qinghai-Tibet Plateau, and those with a percentage lower than 20% were mostly distributed in northwestern China, the southwestern karst region and the North China Plain. In recent decades, ecological conservation has focused on ecol- ogically fragile regions; more than five ecological conservation programs have been imple- mented in most counties of the Three River Source Region in Qinghai Province, southeastern Tibet, western Sichuan, the Qilian Mountains, southern Xinjiang and other western regions, while only one or zero have been implemented in the eastern coastal area of China. Over the past 15 years, the proportional area of high-quality ecosystems has increased in approxi- mately 53% of counties. The vegetation coverage of counties in the Loess Plateau, Huang-Huai-Hai Plain, Beijing-Tianjin-Hebei （Jing-Jin-Ji）, Sichuan-Guizhou-Chongqing, and Guangdong-Guangxi provincial-level areas has increased significantly. However, it decreased in northern Xinjiang, central Tibet, central and eastern Inner Mongolia, the Yangtze River Delta and other regions. The relationships between the numbers of ecological conservation programs and the indicators of ecosystem restoration response, such as high-quality eco- system and vegetation coverage, do not show positive correlations. These results suggest that ecological conservation programs should be planned and implemented according to the distribution patterns of high-quality ecosystems and that restoration measures such as af- forestation should follow natural principles and regional differentiation under the background of climate change.

The development of Fujian’s outward-oriented economy and its regional differentiation

Outward oriented economy in Fujian Province has been developed rapidly since the implementation of open door policy. Regional differentiation is obvious between ethnic Chinese hometown and non ethnic Chinese one; southeast Fujian and other part of the province; and different counties within southeast Fujian. Enterprises with foreign capital make great contribution to the economic development of Fujian.

Regional Differentiation and Classification for Carrying Constraints on the Resources and Environment of China

Research on the relationship between national resource constraint-region types and environmental carrying capacity is essential for the continued development of Chinese industrialization and urbanization.Thus,utilizing a series of key indexes including the per-capita potential of available land resources,the per-capita potential of available water resources,the degree of environmental stress,and the degree of ecological restriction,a step-by-step,integrated measuring method is presented here to understand the constrained carrying elements of water and land resources as well as environment and ecology.Spatial differences are analyzed and area types classified at the county level across China.Results reveal that：（1）Almost 90%of China is strongly constrained by both resources and the environment,while nearly 50%of national territory is strongly constrained by two elements,especially in areas of intensive population and industry to the east of the Helan-Longmen Mountain line;（2）Densely populated areas of eastern and central China,as well as on the Tibetan Plateau,are strongly constrained by a shortage of land resources,while North China,the northwest,northeast,the Sichuan basin,and some southern cities are experiencing strong constraints because of water shortages.In contrast,the North China plain,the Yangtze River delta,northern Jiangsu,Sichuan province,Chongqing municipality,Guizhou and Guangxi provinces,the northeast plain,and the northern Loess Plateau are constrained by high levels of environmental stress.Areas of China that are strongly ecologically constrained tend to be concentrated to the southwest of the Tianshan-Dabie Mountain line,as well as in the northeast on the Loess Plateau,in the Alashan of Inner Mongolia,in northeast China,and in the northern Jiangsu coastal area;（3）Constraints on national resources and environmental carrying capacity are diverse and cross-cut China,meanwhile,multi-element spatial distribution does reveal a degree of relative centralization.With the exception of the Tibetan Plateau which is resources-ecological constraint,other areas subject to cross constraints are mainly concentrated to the east of the Helan-Longmen Mountain line.

EVOLUTION AND DIFFERENTIATION OF THE PHYSICO-EOGRAPHICAL ENVIRONMENT OF THE QINGHAI-XIZANG (TIBETAN) PLATEAU

The intense uplift of the Qinghai-Xizang Plateau givesrise to drastic changes of natural environment and distinctdifferentiation of the Plateau proper. This paper focuses on theevolution of subtropical environment at low altitude to frigidenvironment at high altitude of the region since Pliocene and thechanges effected by cold-warm amplitude bf global change. Bycomparative study on the structure-type of the altitudinal belt, adistributional model diagram with close relevance to highlanduplift effect has been generalized. Based on regjonaldifferentiation of the Qinghai-Xizang Plateau, a number ofstriking geo-ecological phenomena such as moisture corridor, dryvalleys and high cold-arid core area are investigated anddiscussed.

Imprinting at the KBTBD6 locus involves species-specific m ternal methylation and monoallelic expression in livestock animals

Background The primary differentially methylated regions(DMRs) which are maternally hypermethylated serve as imprinting control regions(ICRs) that drive monoallelic gene expression, and these ICRs have been investigated due to their implications in mammalian development. Although a subset of genes has been identified as imprinted, in-depth comparative approach needs to be developed for identification of species-specific imprinted genes. Here, we examined DNA methylation status and allelic expression at the KBTBD6 locus across species and tissues and explored potential mechanisms of imprinting.Results Using whole-genome bisulfite sequencing and RNA-sequencing on parthenogenetic and normal porcine embryos, we identified a maternally hypermethylated DMR between the embryos at the KBTBD6 promoter Cp G island and paternal monoallelic expression of KBTBD6. Also, in analyzed domesticated mammals but not in humans, non-human primates and mice, the KBTBD6 promoter Cp G islands were methylated in oocytes and/or allelically methyl-ated in tissues, and monoallelic KBTBD6 expression was observed, indicating livestock-specific imprinting. Further analysis revealed that these Cp G islands were embedded within transcripts in porcine and bovine oocytes which coexisted with an active transcription mark and DNA methylation, implying the presence of transcription-dependent imprinting.Conclusions In this study, our comparative approach revealed an imprinted expression of the KBTBD6 gene in domesticated mammals, but not in humans, non-human primates, and mice which implicates species-specific evolution of genomic imprinting.

DNA methylation in poultry:a review

As an important epigenetic modification,DNA methylation is involved in many biological processes such as animal cell differentiation,embryonic development,genomic imprinting and sex chromosome inactivation.As DNA methylation sequencing becomes more sophisticated,it becomes possible to use it to solve more zoological problems.This paper reviews the characteristics of DNA methylation,with emphasis on the research and application of DNA methylation in poultry.

Spatial-temporal Differentiation of Sauna Days with Different Intensities in China from 1961 to 2017

Sauna weather with high temperature, high humidity and long standby time has become one of the main meteorological hazards faced by urban residents. Based on the daily maximum temperature and relative humidity datasets of 545 meteorological observation stations in China from 1961 to 2017, the spatial-temporal evolution characteristics of sauna days with different intensities in China were studied from three aspects: climatic state, trend and fluctuation characteristics, using the standard of sauna days defined by the Central Meteorological Observatory of China Meteorological Administration. The results showed that: firstly, the spatial pattern of sauna days with different intensities in China was high in southeast China and low in northwest China from 1961 to 2017, and the spatial pattern of sauna days with the same intensity in different research periods had little difference, which was in good agreement with the spatial pattern of sauna days with corresponding intensities in the whole research period. With the increase of intensity, the sauna days in China decreases gradually. Secondly, the trend of sauna days with different intensities in China was bounded by Hu Huanyong Line from 1961 to 2017, showing a pattern of increasing or decreasing mosaic in the southeast China and mainly decreasing trend, while the spatial differentiation pattern in the northwest China changed little. The trend of sauna days with different intensities in China increased significantly in 1991-2017 compared with 1961-1990. Thirdly, the fluctuation of sauna days with different intensities in China was bounded by Hu Huanyong Line, showing a spatial pattern of large fluctuations in the southeast China and small fluctuations in the northwest China. And the fluctuation of sauna days and heavy sauna days showed obvious threeblock distribution characteristics. The fluctuation characteristics of sauna days with different intensities in China from 1961 to 1990 and 1991 to 2017 were in good agreement with the whole research period. The fluctuation difference before and after 1990 mainly concentrated in the vicinity of Hu Huanyong Line and its southeast area, and the fluctuation differences increased mainly, indicating that the variation of sauna days with different intensities in the southeast China increased from 1991 to 2017.

An Evaluation on the Effects of the Policy of the Great Campaign of Western Development of China in the First 10 Years Based on the Kuznets Regional Inverted-U Theory

In order to reduce the regional differentials or narrow the gap in economic development between eastern and western areas and prevent the intensification of contradictions resulting from the regional inequality during the development process, the government of China launched the Great Campaign of Western Development （GCWD） in 2000. In this paper, we will evaluate the effects of the first 10 years＇ GCWD and use the latest Chinese annual data from 1978 to 2010 to investigate the problem of regional differentials in the development process, evaluate the effects of GCWD policy and test whether there is a regional Kuznets inverted-U curve in the regional development of China. The result shows that there are both good and bad news： the good news is that the inverted U-shaped curve of absolute differential between eastern and western areas finally emerges （the previous studies showed that the inverted-U curve did not appear and the differentials between eastern and western areas became worse） and the bad news is that the differential is in the first half of the inverted U-shaped curve in our choice of time span （1978-2010）, that is, it is still in the situation of deterioration, and the turning better point will emerge in 2025. Although the western areas have benefitted from GCWD, the absolute gap has been still widened. To narrow the gap, the western areas should accelerate the industrial development and the government should adjust the policy and make more efforts to support the development of the industry in the western areas, especially cultivate and support the development of the western characteristic and advantageous industry rather than just supporting the construction of infrastructure in the western areas.

Reduced non-CpG methylation is a potential epigenetic target after spinal cord injury

DNA methylation is a critical epigenetic regulator in the occurrence and development of diseases and is closely related to various functional responses in relation to spinal cord injury.To investigate the role of DNA methylation in spinal cord injury,we constructed a library with reduced-representation bisulfite sequencing data obtained at various time points(day 0-42)after spinal cord injury in mice.Global DNA methylation levels,specifically non-CpG(CHG and CHH)methylation levels,decreased modestly following spinal cord injury.Stages post-spinal cord injury were classified as early(day 0-3),intermediate(day7-14),and late(day 28-42)based on similarity and hie rarchical cluste ring of global DNA methylation patterns.The non-CpG methylation level,which included CHG and CHH methylation levels,was markedly reduced despite accounting for a minor proportion of total methylation abundance.At multiple genomic sites,including the 5’untranslated regions,promoter,exon,intron,and 3’untranslated regions,the non-CpG methylation level was markedly decreased following spinal cord injury,whereas the CpG methylation level remained unchanged at these locations.Approximately one-half of the differentially methylated regions were located in intergenic areas;the other differentially methylated regions in both CpG and non-CpG regions were cluste red in intron regions,where the DNA methylation level was highest.The function of genes associated with differentially methylated regions in promoter regions was also investigated.From Gene Ontology analysis results,DNA methylation was implicated in a number of essential functional responses to spinal cord injury,including neuronal synaptic connection creation and axon regeneration.Notably,neither CpG methylation nor non-CpG methylation was implicated in the functional response of glial or inflammatory cells.In summary,our work elucidated the dynamic pattern of DNA methylation in the spinal co rd following injury and identified reduced nonCpG methylation as an epigenetic target after spinal cord injury in mice.

Climate warming over 1961–2019 and impacts on permafrost zonation in Northeast China

In boreal forest ecosystems, permafrost and forest types are mutually interdependent;permafrost degradation impacts forest ecosystem structure and functions. The Xing’an permafrost in Northeast China is on the southern margin of the Eastern Asia latitudinal permafrost body. Under a warming climate, permafrost undergoes rapid and extensive degradation. In this study, the frost-number (Fn) model based on air temperatures and ground surface temperatures was used to predict the distribution of the Xing’an permafrost, and, temporal and spatial changes in air and ground-surface temperatures from 1961 to 2019 are analyzed. The results show that Northeast China has experienced a rapid and substantial climate warming over the past 60 years. The rises in mean annual air and mean annual ground-surface temperatures were higher in permafrost zones than those in the seasonal frost zone. The frost numbers of air and ground-surface temperatures were calculated for determining the southern limit of latitudinal permafrost and for permafrost zonation. The southern limits of discontinuous permafrost, sporadic permafrost, and latitudinal permafrost moved northward significantly. According to the air-temperature frost-number criteria for permafrost zoning, compared with that in the 1960s, the extent of Xing’an permafrost in Northeast China had decreased by 40.6% by the 2010s. With an average rate of increase in mean annual air temperatures at 0.03 ℃ a^(−1), the extent of permafrost in Northeast China will decrease to 26.42 × 10^(4) by 2020, 14.69 × 10^(4) by 2040 and to 11.24 × 10^(4) km^(2) by 2050. According to the ground-surface temperature frost-number criteria, the southern limit of latitudinal permafrost was at the 0.463. From the 1960s to the 2010s, the extent of latitudinal permafrost declined significantly. Due to the nature of the ecosystem-protected Xing’an-Baikal permafrost, management and protection (e.g., more prudent and effective forest fire management and proper logging of forests) of the Xing’an permafrost eco-environment should be strengthened.

Water pollution and its control in China

Based on comprehensive analysis of the status, major characteristics and regulation of regional differentiation of water pollution in China, the following counter measures for control water pollution were suggested: Overall planning and rational allocation; Comprehensive utilization and technical reform; Strengthening environmental management and the legal system.

Application of Systematic Clustering Method in the Classification and Changes of Atmospheric Ozone in Hunan Province

The cluster analysis method needs continuous improvement and perfection in the research and application of the spatial differentiation and change of pollutants.In this paper,the date of monthly highest concentration of ozone(O_(3))and the concentration value of that day were selected as the similarity coefficient between classes.Single-factor cluster analysis was performed on O_(3)during 2016-2019 and the COVID-19 outbreak of 2020 in Hunan Province using the Ward method.The clustering results showed that the spatial distribution of atmospheric O_(3)in the 14 regions of Hunan Province was most suitable to be classified according to class III clustering areas.That is,the Changsha-Zhuzhou-Xiangtan urban agglomeration was the center,and the high-value area was in northern Hunan.The transition area was in central and southern Hunan,while the low-value area was centered in western Hunan.The partition results were in good agreement with the homogeneous subset of one-way ANOVA and the distribution of monitoring values during the same period.The comparison showed that the inter-class plates in the two periods corresponded well,and the intra-class area showed a continuous geographical distribution,and there were dynamic changes in the spatial differentiation of the O_(3)plates in different periods.In 2020,the center of the O_(3)high-value area plate in Hunan Province moved eastward and extended southward,focusing on the middle and lower reaches of the Xiangjiang River basin,and extending to the upstream area;the regional plate in the transition area expanded significantly;the low-value area plate shrank to the two cities in western Hunan.The abnormal emissions and abnormal climate during the COVID-19 epidemic had an impact on the spatial differentiation of O_(3)in Hunan Province.

Biomechanical forces in atherosclerosis-susceptible and -resistant regions of human vasculature differentially regulate endothelial vaso-protective phenotypes

Introduction Atherosclerosis is a potentially life-threatening disease of large arteries that is strongly associated with systemic risk factors such as hypercholesterolemia,hypertension,smoking,and diabetes. However,atherosclerosis develops as a

The Genetic Structure and Diversity of Repomucenus curvicornis Inhabiting Liaoning Coast Based on Mitochondrial COⅠ Gene and Control Region

[Object] This study was conducted to explore the genetic diversity and structure of the wild Repomucenus curvicornis inhabiting Liaoning Coast, China. [Method] The mitochondrial COⅠ gene and control region（CR） were PCR amplified from the wild R. curvicornis populations from the Liaodong Bay（n=22） and the northern Yellow Sea（n=18）, sequenced and analyzed for genetic diversity. [Result] The contents of A, T, C and G of 624 bp COⅠ gene were 24.09%, 31.04%, 25.28%, and 19.59%, and those of 460 bp CR fragment were 32.96%, 32.80%, 14.86% and 19.38%, respectively. The total number of variable sites, average number of nucleotide differences（ k）, haplotype diversity（H） and nucleotide diversity（π） based on COⅠ gene were 38, 4.67,（0.96±0.02） and（0.007 5±0.004 2）, and those based on CR fragment were 26, 3.35,（0.97 ±0.02） and（0.007 3±0.004 3）, respectively. Based on mitochondrial COⅠ gene and CR, the genetic diversity of Liaodong Bay population was lower than that of the northern Yellow Sea population. The AMOVA analysis based on CR fragments revealed almost significant genetic divergence between the Liaodong Bay and the northern Yellow Sea populations, while there was no significant genetic divergence based on COⅠ gene. The results showed that CR and COⅠ gene are effective molecular markers for detecting the genetic diversity of R. curvicornis population, while CR is more reliable than COⅠ gene in detecting the genetic structure. [Conclusion] CR is an appropriate marker for genetic analysis of marine fish population.

Impact of cultivated land fragmentation on spatial heterogeneity of agricultural agglomeration in China

Systematically revealing the impact of cultivated land fragmentation(CLF)on the geographical agglomeration pattern of agricultural specialization(AS)has positive significance for national agricultural production management.Based on the data of the second national land survey and agricultural production,this study has explored the impact of CLF on spatial heterogeneity of agricultural agglomeration in China by comprehensively using the Theil index,ordinary least square model and geographically weighted regression.Results showed that:(1)the regional differentiation of the CLF in China is obvious,and the cultivated land fragmentation index is generally characterized by increasing pattern from northwest to southeast.(2)Spatially,the development level of AS in China has formed three high-value clusters in the Northeast China Plain,the Qinghai-Tibet Plateau,and the middle of the Middle-lower Yangtze Plain;and the low-value contiguous areas centered on the Yunnan-Guizhou Plateau and the Sichuan Basin and surrounding regions,with significant spatial differences.The contribution of grain crops,economic crops,and vegetables and melon to the level of AS was 74.63%,9.09%,and 16.28%,respectively,and the pattern of agricultural geographical aggregation dominated by grain crops has primarily taken in shape.(3)CLF is significantly negatively correlated with AS,and every 1%increase in the degree of CLF will result in a decrease of about 0.2%in AS.However,the impact of CLF on the geographic agglomeration of different crop categories or groups varies significantly.Among them,CLF has a prominent impact on the specialization level of grain crops and vegetables and melon.Each 1%increase in the CLF will reduce the specialization level of grain crops by 0.38%,and increase the level of vegetables and melon by about 0.22%.(4)According to the landscape characteristics of cultivated land,the degree of spatial division and agglomeration of cultivated land patches have a significant impact on the formation of geographical agglomerationpattern of AS,and the intensity and direction of influence show significant regional differentiation,while the patch size has no significant impact.