Eastern Black Sea Region in northeastern part of Turkey has the highest precipitation total in the country, approaching 2500 mm per a year. It is therefore an important region as it frequently encounters with flash fl...Eastern Black Sea Region in northeastern part of Turkey has the highest precipitation total in the country, approaching 2500 mm per a year. It is therefore an important region as it frequently encounters with flash floods due to heavy rains. For future planning of water resources, environment and urbanization, it is important to know the expected behavior of hydrometeorological processes, mainly precipitation and flow. Due to these facts, in this study, homogeneity of long-term annual precipitation and streamflow series of the Eastern Black Sea Region, Turkey is checked using double mass curve method and trends are determined by means of the Mann-Kendall test. The data network consists of 38 precipitation gauging stations and 40 flow gauging stations across the Eastern Black Sea Region. It is found that 27 precipitation stations out of 38 are homogeneous and no trend is available. Out of the remaining stations, nine are found non-homogeneous and four with trend. For annual flow data, it is found that 22 stations out of 40 are homogeneous and no trend is available. The remaining 18 stations are found non-homogeneous, among which 5 stations have trend at the same time.展开更多
BACKGROUND Major depression disorder(MDD)constitutes a significant mental health concern.Epidemiological surveys indicate that the lifetime prevalence of depression in adolescents is much higher than that in adults,wi...BACKGROUND Major depression disorder(MDD)constitutes a significant mental health concern.Epidemiological surveys indicate that the lifetime prevalence of depression in adolescents is much higher than that in adults,with a corresponding increased risk of suicide.In studying brain dysfunction associated with MDD in adolescents,research on brain white matter(WM)is sparse.Some researchers even mistakenly regard the signals generated by the WM as noise points.In fact,studies have shown that WM exhibits similar blood oxygen level-dependent signal fluctuations.The alterations in WM signals and their relationship with disease severity in adolescents with MDD remain unclear.AIM To explore potential abnormalities in WM functional signals in adolescents with MDD.METHODS This study involved 48 adolescent patients with MDD and 31 healthy controls(HC).All participants were assessed using the Patient Health Questionnaire-9 Scale and the mini international neuropsychiatric interview(MINI)suicide inventory.In addition,a Siemens Skyra 3.0T magnetic resonance scanner was used to obtain the subjects'image data.The DPABI software was utilized to calculate the WM signal of the fractional amplitude of low frequency fluctuations(fALFF)and regional homogeneity,followed by a two-sample t-test between the MDD and HC groups.Independent component analysis(ICA)was also used to evaluate the WM functional signal.Pearson’s correlation was performed to assess the relationship between statistical test results and clinical scales.RESULTS Compared to HC,individuals with MDD demonstrated a decrease in the fALFF of WM in the corpus callosum body,left posterior limb of the internal capsule,right superior corona radiata,and bilateral posterior corona radiata[P<0.001,family-wise error(FWE)voxel correction].The regional homogeneity of WM increased in the right posterior limb of internal capsule and left superior corona radiata,and decreased in the left superior longitudinal fasciculus(P<0.001,FWE voxel correction).The ICA results of WM overlapped with those of regional homogeneity.The fALFF of WM signal in the left posterior limb of the internal capsule was negatively correlated with the MINI suicide scale(P=0.026,r=-0.32),and the right posterior corona radiata was also negatively correlated with the MINI suicide scale(P=0.047,r=-0.288).CONCLUSION Adolescents with MDD involves changes in WM functional signals,and these differences in brain regions may increase the risk of suicide.展开更多
The world animal geographical regionalization scheme and the plant geographical regionalization scheme have been formulated by zoologists and botanists respectively since the biogeography has been established.This res...The world animal geographical regionalization scheme and the plant geographical regionalization scheme have been formulated by zoologists and botanists respectively since the biogeography has been established.This research team initially confirmed the homogeneity of Chinese animal and plant geography.To explore the relationship between the distribution pattern of global animals,plants,and microorganisms,global 141,814 genera of terrestrial animals,17,526 genera of plants,21,321 genera of microorganisms,and their major taxa were analyzed using their proposed SGF(Similarity General Formula)and a new multivariate similarity clustering analysis method.Almost identical analytical results were obtained,meeting the requirements of statistics,geography,ecology and biology respectively.The expected consistency of their distribution pattern was achieved for the first time.We prove that the earth’s ecological conditions affect the homogeneity and accumulation of the distribution of animals,plants and microorganisms.Homogeneity determines the distribution pattern of global kinds of biological consistency,accumulation determines the impact of the evolutionary period on the breadth of distribution,microorganisms appear earliest,plants second,animals later,and their average distribution domain decreases in turn,reflecting these differences.Therefore,this study not only provides a theoretical basis and quantitative basis for the establishment of geographical regionalization scheme but also advances the development of biogeography to a new stage and raises the theory of biogeographic analysis to a new height.展开更多
OBJECTIVE: To determine differences in cerebral activity evoked by acupuncture and conventional stroke treatment, and identify the treatment targets.METHODS: In total, 21 patients were randomly divided into two groups...OBJECTIVE: To determine differences in cerebral activity evoked by acupuncture and conventional stroke treatment, and identify the treatment targets.METHODS: In total, 21 patients were randomly divided into two groups. Group A(11 patients) received both acupuncture and conventional treatment, while group B(10 patients) received conventional treatment only. Resting-state functional magnetic resonance imaging(f MRI) was performed on each participant before and after treatment. Regional homogeneity analysis was performed to investigate the potential mechanism of acupuncture treatment by comparing differences in cerebral activity between treatments.RESULTS: Group A showed higher Re Ho in the frontal lobe(BA6, BA46), supra-marginal gyrus(BA40),middle temporal gyrus(BA21), cerebellum, and insula. Group B showed higher Re Ho in the frontal lobe(BA6) and parietal lobe(BA3, BA7).CONCLUSION: Acupuncture and conventional treatment triggered relatively different clinical efficacy and brain responses. Acupuncture treatment more significantly improved the symptoms of stroke patients. More marked changes in sensory,emotional, and motor areas(including the frontal lobe, middle temporal gyrus, cerebellum, and insula) might reflect the specific acupuncture mechanism.展开更多
目的运用静息态功能磁共振成像(resting-state function magnetic resonance imaging,rs-fMRI)探究太极拳零基础者在太极拳不同学习阶段的脑功能活动的局部一致性(regional homogeneity,ReHo)变化。材料与方法采用被试内设计,对18名太...目的运用静息态功能磁共振成像(resting-state function magnetic resonance imaging,rs-fMRI)探究太极拳零基础者在太极拳不同学习阶段的脑功能活动的局部一致性(regional homogeneity,ReHo)变化。材料与方法采用被试内设计,对18名太极拳零基础被试在太极拳学习初期(2周)和学习14周进行同样内容的静息态功能磁共振成像检查。然后分别计算前后两个不同时间点被试的全脑ReHo值并进行相关统计学分析。结果与太极拳学习2周比较,太极拳学习14周被试右侧梭状回的ReHo值显著增高,而右侧小脑和左侧顶上小叶的ReHo值显著降低(AlphaSim校正P<0.05);其中右侧小脑的ReHo的变化值与太极拳技能评分的变化值呈显著负相关(r=-0.507,P=0.032)。多元回归分析发现,太极拳学习2周被试的右侧颞中回、右侧前扣带回的ReHo值与太极拳技能评分的变化量呈显著正相关(r=0.908、0.818,P<0.01),而左侧枕下回及右侧颞上回的ReHo值与太极拳技能评分的变化量呈显著负相关(r=-0.474,P<0.05;r=-0.824,P<0.01)。结论研究结果表明,随着太极拳学习技能水平的提高,被试的静息态功能活动局部一致性变化,反映了相关脑区可塑性。另外,太极拳学习初期某些脑区的ReHo值对太极拳技能学习效果有一定的潜在预测作用。展开更多
文摘Eastern Black Sea Region in northeastern part of Turkey has the highest precipitation total in the country, approaching 2500 mm per a year. It is therefore an important region as it frequently encounters with flash floods due to heavy rains. For future planning of water resources, environment and urbanization, it is important to know the expected behavior of hydrometeorological processes, mainly precipitation and flow. Due to these facts, in this study, homogeneity of long-term annual precipitation and streamflow series of the Eastern Black Sea Region, Turkey is checked using double mass curve method and trends are determined by means of the Mann-Kendall test. The data network consists of 38 precipitation gauging stations and 40 flow gauging stations across the Eastern Black Sea Region. It is found that 27 precipitation stations out of 38 are homogeneous and no trend is available. Out of the remaining stations, nine are found non-homogeneous and four with trend. For annual flow data, it is found that 22 stations out of 40 are homogeneous and no trend is available. The remaining 18 stations are found non-homogeneous, among which 5 stations have trend at the same time.
基金Supported by the Suzhou Clinical Medical Center for Mood Disorders,No.Szlcyxzx202109Jiangsu Provincial Department of Science and Technology for Social Development-General Project,No.BE2022735.
文摘BACKGROUND Major depression disorder(MDD)constitutes a significant mental health concern.Epidemiological surveys indicate that the lifetime prevalence of depression in adolescents is much higher than that in adults,with a corresponding increased risk of suicide.In studying brain dysfunction associated with MDD in adolescents,research on brain white matter(WM)is sparse.Some researchers even mistakenly regard the signals generated by the WM as noise points.In fact,studies have shown that WM exhibits similar blood oxygen level-dependent signal fluctuations.The alterations in WM signals and their relationship with disease severity in adolescents with MDD remain unclear.AIM To explore potential abnormalities in WM functional signals in adolescents with MDD.METHODS This study involved 48 adolescent patients with MDD and 31 healthy controls(HC).All participants were assessed using the Patient Health Questionnaire-9 Scale and the mini international neuropsychiatric interview(MINI)suicide inventory.In addition,a Siemens Skyra 3.0T magnetic resonance scanner was used to obtain the subjects'image data.The DPABI software was utilized to calculate the WM signal of the fractional amplitude of low frequency fluctuations(fALFF)and regional homogeneity,followed by a two-sample t-test between the MDD and HC groups.Independent component analysis(ICA)was also used to evaluate the WM functional signal.Pearson’s correlation was performed to assess the relationship between statistical test results and clinical scales.RESULTS Compared to HC,individuals with MDD demonstrated a decrease in the fALFF of WM in the corpus callosum body,left posterior limb of the internal capsule,right superior corona radiata,and bilateral posterior corona radiata[P<0.001,family-wise error(FWE)voxel correction].The regional homogeneity of WM increased in the right posterior limb of internal capsule and left superior corona radiata,and decreased in the left superior longitudinal fasciculus(P<0.001,FWE voxel correction).The ICA results of WM overlapped with those of regional homogeneity.The fALFF of WM signal in the left posterior limb of the internal capsule was negatively correlated with the MINI suicide scale(P=0.026,r=-0.32),and the right posterior corona radiata was also negatively correlated with the MINI suicide scale(P=0.047,r=-0.288).CONCLUSION Adolescents with MDD involves changes in WM functional signals,and these differences in brain regions may increase the risk of suicide.
文摘The world animal geographical regionalization scheme and the plant geographical regionalization scheme have been formulated by zoologists and botanists respectively since the biogeography has been established.This research team initially confirmed the homogeneity of Chinese animal and plant geography.To explore the relationship between the distribution pattern of global animals,plants,and microorganisms,global 141,814 genera of terrestrial animals,17,526 genera of plants,21,321 genera of microorganisms,and their major taxa were analyzed using their proposed SGF(Similarity General Formula)and a new multivariate similarity clustering analysis method.Almost identical analytical results were obtained,meeting the requirements of statistics,geography,ecology and biology respectively.The expected consistency of their distribution pattern was achieved for the first time.We prove that the earth’s ecological conditions affect the homogeneity and accumulation of the distribution of animals,plants and microorganisms.Homogeneity determines the distribution pattern of global kinds of biological consistency,accumulation determines the impact of the evolutionary period on the breadth of distribution,microorganisms appear earliest,plants second,animals later,and their average distribution domain decreases in turn,reflecting these differences.Therefore,this study not only provides a theoretical basis and quantitative basis for the establishment of geographical regionalization scheme but also advances the development of biogeography to a new stage and raises the theory of biogeographic analysis to a new height.
基金Supported by the National Natural Science Foundation of China(NSFC):Acupoint Sensitization Research(No.81590950)the State Key Program for Basic Research of China:Clinical Evaluation of the Basic Rules of Acupoint Specification and Basic Biological Study on CNS Targeting Integration(No.2012CB518501)NSFC:Study on the CNS Integration Mechanism of Spine-dredging Technique in Treating Ischemia Stroke(No.81072864)
文摘OBJECTIVE: To determine differences in cerebral activity evoked by acupuncture and conventional stroke treatment, and identify the treatment targets.METHODS: In total, 21 patients were randomly divided into two groups. Group A(11 patients) received both acupuncture and conventional treatment, while group B(10 patients) received conventional treatment only. Resting-state functional magnetic resonance imaging(f MRI) was performed on each participant before and after treatment. Regional homogeneity analysis was performed to investigate the potential mechanism of acupuncture treatment by comparing differences in cerebral activity between treatments.RESULTS: Group A showed higher Re Ho in the frontal lobe(BA6, BA46), supra-marginal gyrus(BA40),middle temporal gyrus(BA21), cerebellum, and insula. Group B showed higher Re Ho in the frontal lobe(BA6) and parietal lobe(BA3, BA7).CONCLUSION: Acupuncture and conventional treatment triggered relatively different clinical efficacy and brain responses. Acupuncture treatment more significantly improved the symptoms of stroke patients. More marked changes in sensory,emotional, and motor areas(including the frontal lobe, middle temporal gyrus, cerebellum, and insula) might reflect the specific acupuncture mechanism.
文摘目的运用静息态功能磁共振成像(resting-state function magnetic resonance imaging,rs-fMRI)探究太极拳零基础者在太极拳不同学习阶段的脑功能活动的局部一致性(regional homogeneity,ReHo)变化。材料与方法采用被试内设计,对18名太极拳零基础被试在太极拳学习初期(2周)和学习14周进行同样内容的静息态功能磁共振成像检查。然后分别计算前后两个不同时间点被试的全脑ReHo值并进行相关统计学分析。结果与太极拳学习2周比较,太极拳学习14周被试右侧梭状回的ReHo值显著增高,而右侧小脑和左侧顶上小叶的ReHo值显著降低(AlphaSim校正P<0.05);其中右侧小脑的ReHo的变化值与太极拳技能评分的变化值呈显著负相关(r=-0.507,P=0.032)。多元回归分析发现,太极拳学习2周被试的右侧颞中回、右侧前扣带回的ReHo值与太极拳技能评分的变化量呈显著正相关(r=0.908、0.818,P<0.01),而左侧枕下回及右侧颞上回的ReHo值与太极拳技能评分的变化量呈显著负相关(r=-0.474,P<0.05;r=-0.824,P<0.01)。结论研究结果表明,随着太极拳学习技能水平的提高,被试的静息态功能活动局部一致性变化,反映了相关脑区可塑性。另外,太极拳学习初期某些脑区的ReHo值对太极拳技能学习效果有一定的潜在预测作用。
