Lymph node dissection does not affect the survival of patients with tumor node metastasis stages Ⅰ and Ⅱ colorectal cancer

BACKGROUND The effect of the number of lymph node dissections(LNDs)during radical resection for colorectal cancer(CRC)on overall survival(OS)remains controver-sial.AIM To investigate the association between the number of LNDs and OS in patients with tumor node metastasis(TNM)stage Ⅰ–Ⅱ CRC undergoing radical resection.METHODS Patients who underwent radical resection for CRC at a single-center hospital between January 2011 and December 2021 were retrospectively analyzed.Cox regression analyses were performed to identify the independent predictors of OS at different T stages.RESULTS A total of 2850 patients who underwent laparoscopic radical resection for CRC were enrolled.At stage T1,age[P<0.01,hazard ratio(HR)=1.075,95%confidence interval(CI):1.019-1.134]and tumour size(P=0.021,HR=3.635,95%CI:1.210-10.917)were independent risk factors for OS.At stage T2,age(P<0.01,HR=1.064,95%CI:1.032-1.098)and overall complications(P=0.012,HR=2.297,95%CI:1.200-4.397)were independent risk factors for OS.At stage T3,only age(P<0.01,HR=1.047,95%CI:1.027-1.066)was an independent risk factor for OS.At stage T4,age(P<0.01,HR=1.057,95%CI:1.039-1.075)and body mass index(P=0.034,HR=0.941,95%CI:0.890-0.995)were independent risk factors for OS.However,there was no association between LNDs and OS in stages Ⅰ and Ⅱ.CONCLUSION The number of LDNs did not affect the survival of patients with TNM stages Ⅰ and Ⅱ CRC.Therefore,insufficient LNDs should not be a cause for alarm during the surgery.

Effects of disparity distribution on visual comfort for multiple objects of stereoscopic images

With the development of stereoscopic technology, more attention is attracted on the stereoscopic three-dimensional(S3 D) content and service, and researches on images and videos have emerged in large numbers. This paper focuses mainly on visual comfort affected by characteristics of disparity for multiple objects. To find the relationship between disparity distribution and visual comfort perception, several subject evaluation experiments are done. The study contains two spatial distribution types of disparity: 1) only one of the foreground objects has zero disparity; 2) one of the foreground objects has positive disparity, while the other one has negative disparity. The experimental results and relative regression analysis provide appropriate relationship between disparity distribution and visual comfort for both conditions, which is significant to meet the applicant field in S3 D content acquisition, display adjustment and quality evaluation.

Risk Factor Analyses for the Return of Spontaneous Circulation in the Asphyxiation Cardiac Arrest Porcine Model

Background： Animal models of asphyxiation cardiac arrest （ACA） are frequently used in basic research to mirror the clinical course of cardiac arrest （CA）. The rates of the return of spontaneous circulation （ROSC） inACA animal models are lower than those from studies that have utilized ventricular fibrillation （VF） animal models. The purpose of this study was to characterize the factors associated with the ROSC in the ACA porcine model. Methods： Forty-eight healthy miniature pigs underwent endotracheal tube clamping to induce CA. Once induced, CA was maintained untreated for a period of 8 min. Two minutes following the initiation of cardiopulmonary resuscitation （CPR）, defibrillation was attempted until ROSC was achieved or the animal died. To assess the factors associated with ROSC in this CA model, logistic regression analyses were performed to analyze gender, the time of preparation, the amplitude spectrum area （AMSA） from the beginning of CPR and the pH at the beginning of CPR. A receiver-operating characteristic （ROC） curve was used to evaluate the predictive value ofAMSA for ROSC. Results： ROSC was only 52.1% successful in this ACA porcine model. The multivariate logistic regression analyses revealed that ROSC significantly depended on the time of preparation, AMSA at the beginning of CPR and pH at the beginning of CPR. The area under the ROC curve in for AMSA at the beginning of CPR was 0.878 successful in predicting ROSC （95% confidence intervals： 0.773-0.983）, and the optimum cut-offvalue was 15.62 （specificity 95.7% and sensitivity 80.0%）. Conclusions： The time of preparation, AMSA and the pH at the beginning of CPR were associated with ROSC in this ACA porcine model. AMSA also predicted the likelihood of ROSC in this ACA animal model.