Regulative Effects of Auricular Acupuncture,Moxibustion and Chinese Herbs on Immunologic Function in the D-Galactose-induced Aging Mouse

Objective:To observe the regulative effect of auricular acupuncture, moxibustion and Chinese herbs on immunologic function in the D-galactose-induced aging mouse and to probe the feasibility and possible mechanisms for delaying aging, so as to provide experimental basis for acupuncture, moxibustion and Chinese herbs for delaying aging. Methods: Aging mouse model was established by subcutaneous injection of D-galactose, and treated by auricular acupuncture, auricular acupuncture plus moxibustion, and auricular acupuncture plus Chinese herbs respectively for 6 weeks and then serum interleukin-2 (IL-2) and IL-6 contents and splenic lymphocyte transformation rate were compared among the groups. Results: Compared with the young group, the serum IL-2 level and the splenic lymphocyte transformation rate significantly decreased and the IL-6 level significantly increased in the aging mouse. After treatment by auricular acupuncture, auricular acupuncture plus Chinese herbs, especially auricular acupuncture plus moxibustion, the serum IL-2 level and the splenic lymphocyte transformation rate significantly increased, and the IL-6 level significantly decreased as compared with the model group. Conclusions: Combined application of auricular acupuncture, moxibustion and Chinese herbs can improve the decline or dysfunction of immunological function in the aging organism to a certain extent.

Effects of Traditional Chinese Medicine herbs for tonifying Qi and kidney, and replenishing spleen on intermittent asthma in children aged 2 to 5 years old

OBJECTIVE: To evaluate the efficacy and safety of Traditional Chinese Medicine(TCM) herbs for tonifying Qi and kidney, and replenishing spleen on intermittent asthma in children aged 2 and 5 years.METHODS: A randomized, single-blind, placebo controlled trial was conducted. Children with intermittent asthma were enrolled and their baseline conditions were measured using a questionnaire. A total of 60 participants, aged 2 to 5, were randomized into either the treatment group(n = 40) or the placebo group(n = 20). The treatment group was treated with granules of TCM herbs for tonifying Qi and kidney, and replenishing spleen, and the placebo group was given placebo granules for 3 months.The number of asthma attacks was counted and TCM syndrome scores were measured at 1, 2, 3, 6, 9,and 12 months. The airway resistance and levels of eosinophil cationic protein for the two groups were observed before and after 3 months. The results were statistically analyzed.RESULTS: Compared with the placebo group, the number of asthma attacks significantly decreased in the treatment group(P < 0.05). For the treatment group, the TCM syndrome scores decreased after 1 and 2 months; there was also a significant difference in scores between the two groups(P < 0.05).The difference remained after the medicine was stopped for 9 months(P < 0.05). After the 3-month treatment, compared with the placebo group, the airway resistance decreased in the treatment group(P < 0.05). No adverse events were reported in the treatment group.CONCLUSION: The TCM herbs for tonifying Qi and kidney, and replenishing spleen reduced the number of intermittent asthma attacks, decreased the TCM syndrome scores, and reduced the airway resistance in the children aged 2 to 5.

李顺民“健脾益肾二补五通”法治疗慢性肾衰经验总结

李顺民教授从事中医肾病临床教学科研40多年,临床诊疗经验丰富。李教授认为慢性肾衰早中晚期的临床表现主要以脾胃化生气血功能异常为主,基本病机以脾肾气虚为本,湿瘀浊毒为标。治疗应精准把握本虚标实、脾虚气血生化乏源这一主要矛盾,倡导肾病从脾论治,补土生水,打通泄浊通路,祛湿化瘀排浊毒,主张“健脾益肾,二补五通”,即补脾补肾,通大便,通小便,通汗液,通呼吸,通血脉。只有脾旺土肥,胃气强健,气血生化有源,肾之精气得以充养,肾之气化功能才能正常发挥。只要脾肾功能正常,则大便顺,小便调;肺气宣,呼吸畅;心气足,血脉通。二补以固本,五通以祛邪。正气驱毒外出,邪去则正安。临床应用表明,该法对慢性肾衰的保健和康复有明显的治疗、阻断与延缓作用,可供同道借鉴和探讨。

升阳益气 固肾化瘀治疗慢性肾炎蛋白尿疗效观察

目的:观察升阳益气、固肾化瘀方法治疗慢性肾炎蛋白尿的临床疗效。方法:用升阳益气、固肾化瘀中药组方配合水蛭、冬虫夏草、五倍子等打粉装入胶囊服用,随机设常规西药治疗对照组。分别检测蛋白尿/24h、ALB、TP、BUN、Scr等。结果:中药治疗慢性肾炎蛋白尿52例,有效率92.31%,在纠正尿蛋白的同时改善低蛋白血症和肾功能,优于对照组的75%,有显著性差异(P<0.05)。结论:运用升阳益气、固肾化瘀方法辨证组方治疗慢性肾炎蛋白尿疗效可靠。

益肾健脾涤痰散结法治疗心脑血管疾病的机制研究

"益肾健脾,涤痰散结"在心脑血管疾病中的应用,源于临床实践,又经过长期的临床与系列实验研究验证、深化,已广泛应用于冠心病心绞痛、心律失常、高血压病、中风等心脑血管疾病临证治疗中。其代表方补肾抗衰片能够明显改善肾虚痰瘀型冠心病心绞痛患者胸痹心痛证候,具有良好的抗氧化、抗酪氨酸硝基化的作用,而活性氧自由基(ROS)和活性氮自由基(RNS)可能是"痰"的物质基础。补肾抗衰片的系列研究,进一步证实了"脾虚生痰,痰瘀互结"是心脑血管病的病理基础,而"益肾健脾,涤痰散结"法具有减轻动脉粥样硬化类疾病的作用,成为指导心脑血管疾病防治的一个重要应用理论。

基于“益火补土”理论探析脾肾阳虚型老年功能性便秘针刺治疗

功能性便秘是指排除了代谢性、器质性和系统性疾病之后的便秘,表现为排便次数和量的减少、排便困难或不畅,以及粪便质地硬等,是临床常见的消化系统疾病。中医学对便秘的认识由来已久,早在《黄帝内经》中就提到"大便难""不便"等。持续性的便秘可继发痔疮,诱发一系列胃肠道疾病。随着老龄化的不断深入,我国老年人口比重逐年上升,老年性功能性便秘受到高度关注。社会经济高速发展,生活质量不断提高,人们已逐渐认识到便秘给机体带来的严重危害性,因此,如何改善和预防功能性便秘引起医学工作者的热议。现代医学对此疾病的治疗大多选用手术、泻药等治疗方法,其副作用较大。中医治疗辨证施治,顾护脾胃,安全性高。该文主要在"益火补土"理论指导下,从针灸处方选穴原则出发,探讨针灸治疗老年功能性便秘的理论研究。

《临证指南医案》辨治情志致病的特色

情志是中医学常见的致病原因。清代著名医家叶天士对情志致病拥有丰富的临床经验。《临证指南医案》是反映其学术思想和临床经验的关键著作,记载着大量与情志相关的医案。阐释情志致病的内涵,并将其与情志病、心身疾病的概念加以区分;分析总结《临证指南医案》的情志致病以肝胆、心、脾为核心的辨治原则,主要采用泄肝培土、益(清)心补肾、理肺疏郁、辛开苦降、移情易性5种治疗方法,从而为临床诊疗提供更多的思路。

贾建华治疗结直肠癌术后患者经验

[目的]总结贾建华主任医师治疗结肠癌术后患者的经验。[方法]通过跟师学习、分析研究贾师的结直肠癌术后临床医案,从病因病机、治疗原则、治疗方法、经验用药等方面总结贾师治疗结直肠癌术后患者的临床思想,并附验案佐证。[结果]贾师认为结直肠癌的总病机是邪盛正衰,当采取扶正祛邪的治疗总则,临床上具体采用补脾益肾、化痰祛瘀、清热解毒的治法,疗效显著。所举验案以补脾益肾为主,兼以化痰祛瘀、清热解毒治疗,取得较好疗效。[结论]贾师以扶正祛邪为治则,以补脾益肾、化痰祛瘀、清热解毒为治法,治疗结直肠癌术后患者疗效显著,值得推广。

升阳益胃汤临床应用浅析

从《脾胃论》入手,运用中医学理论,对升阳益胃汤进行探讨,揭示本方立方宗旨、治疗功效、适应病证的理论依据,以及本方在药物组成、方剂配伍方面的特点。结合临床运用观察,显示本方对因脾胃虚损、清阳不升引起的多种疾病,有显著的疗效和广泛的应用前景。

“培土生金法”对肺癌中晚期化疗减毒增效作用探讨

化疗是目前治疗中晚期肺癌的主要手段,但由其带来的毒副作用以及并发症明显。中医所主张的"培土生金法",在于顾护脾胃、扶助正气,将中医中药与化疗相结合,可以保证化疗周期的顺利进行,减毒增效,提高生活质量,效果令人满意。

中西医结合治疗小儿肾病综合征临床研究

目的:观察中西医结合治疗小儿肾病综合征的临床疗效。方法:将80例原发性肾病综合征患儿按照随机数字表法分为观察组和对照组,每组各40例。对照组采用强的松治疗,观察组在对照组的基础上中医分期辨证施治,观察分析两组患者的治疗情况。结果:观察组患儿24小时尿蛋白定量、血浆白蛋白、肾功能变化、血液流变学指标显著优于对照组,差异有统计学意义(P<0.05)。观察组有效率为92.5%,对照组有效率为72.5%,两组有效率比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗小儿原发性肾病综合征疗效显著,改善临床症状。