Combined development of traditional Chinese medicine and interventional medicine

The combination of Traditional Chinese Medicine and Interventional Radiology has an excellent clinical effect.This paper reviews the principles and methods of the combined application of Traditional Chinese Medicine and Interventional Radiology,aiming to promote the complementary and coordinated development of Traditional Chinese Medicine and Interventional Radiology.

Analysis of the Effects on Self-Efficacy and Quality of Life of Patients Undergoing Coronary Intervention by Traditional Chinese Medicine Nursing Combined with Refined Nursing

OBJECTIVE: To study the effects on self-efficacy and quality of life in patients undergoing coronary intervention, by traditional Chinese medicine nursing combined with refined nursing. METHODS: A total of 124 patients, who needed to undergo coronary intervention in our hospital, were randomly divided into the fine group and the combined group, with 62 patients in each group. The two groups of patients were enrolled in the PCI routine nursing procedure, in which the fine group was given refined nursing, and the joint group, based on that, added the traditional Chinese medicine nursing. The self-management (self-management scale of coronary heart disease), self-efficacy (self-efficacy scale of coronary heart disease), quality of life score (Seattle angina questionaire (SAQ), TCM symptom score] of the two groups were observed before and after treatment. The incidence of postoperative complications after nursing intervention was recorded. RESULTS: After nursing intervention, each score and total scores of the self-administration scale of the combined group were higher than those of the fine group (P < 0.05). After the nursing intervention, each score and the total scores of the self-efficacy scale of the combined group were higher than the fine group (P < 0.05) After the nursing intervention, the SAQ score of the combined group was significantly higher than that of the fine group (P < 0.05). After the nursing intervention, TCM symptom score of the combined group was significantly lower than that of the fine group (P < 0.05). After nursing intervention, the postoperative complication rate of the combined group was 79.03%, which was lower than that of the fine group (59.68%)(P < 0.05). CONCLUSION: Patients with coronary intervention, who use traditional Chinese medicine combined with refined nursing, can improve their quality of life, clinical symptoms and postoperative complications by improving their self-management and efficacy, which is conducive to the recovery of patients' follow-up.

Construction of Complex Intervention in Traditional Chinese Medicine (TCM): A Preliminary Methodological Study Based on Text Mining and Interviewing Method

Aim: To explore and analyze the feasibility of establishing a program of complex intervention in Traditional Chinese Medicine (TCM) based on Text Mining and Interviewing method. Methods: According to MRC, Constructing the program of complex intervention in TCM by Text Mining and Interviewing method should include 4 steps: 1) establishment of interview framework via normalization of extraction of ancient documents and Effectiveness of collection of modern periodical literatures;2) materialization of interview outline based on Focus Group Interview;3) rudimentary construction of complex intervention program based on Semi-structured Interview;4) evaluation of curative effect of complex intervention. Conclusions: It is feasible and significative to establish a program of complex intervention in TCM based on Text Mining and Interviewing method.

Prevention of violence risk and interventions of Chinese and western medicine nursing on emotion

Accumulation of bad emotion with patients and their relations added violence risk.Workplace violence of nursing is an acute injury to nurse,and long-term threats and challenges to their physical and mental health and professional values. It also has an potential problem on parties negotiate the settlement of medical disputes,as well as boosting reform of national health system.Identifying and managing patients' emotion has positive impact on doubts and resentments elimination,anger escalation avoidance,violence prevention. This study proposed emotional intervention program in terms of traditional Chinese medicine and modern nursing care,which based on introducing the research status on nursing workplace violence. The purpose is to culture the ability of patients' self-identification and emotions regulation,take effective protective measure. The research provides the reference on perfecting the medical security system and related policy research.

Traditional Chinese medicine for promoting mental health of patients with COVID-19:a scoping review

Objective:This study aimed to systematically review and depict the current studies of traditional Chinese medicine for the mental health of patients with coronavirus disease 2019(COVID-19).Methods:A scoping review was conducted by searching PubMed,Web of Science,CNKI,Wanfang database,VIP database,and SinoMed,with the retrieval time being from the establishment of the database to April 18,2022.The basic information of the included studies,objective,design,types of patients,interventions,outcomes,etc.,was reviewed and summarized narratively.Methodological quality was assessed using the Cochrane Risk of Bias assessment tool,the methodological index for nonrandomized studies or the Newcastle-Ottawa scale.Results:We identified 30 traditional Chinese medicine(TCM)studies from six databases.Among them,finished randomized controlled trials(n=16)accounted for most of the studies,followed by single-arm studies(n=9).In terms of study theme,20 studies defined the mental health of patients with COVID-19 as the research theme.Psychological assessment was included in the inclusion criteria(performed before participation)of nine studies,whereas the other studies only mentioned the mental outcomes.TCM interventions included TCM exercises(Yijinjing,Baduanjin,Liuzijue,Taichi),acupoint stimulation(auricular and body points),moxibustion,decoction,or granules based on TCM syndrome differentiation,decoction,or granules with fixed formulae(Baidu Jieduan granules,Xuanfei Baidu decoction,and Qingfei Paidu decoction),Chinese patent medicine(Jinhua Qinggan granules),TCM psychological therapy(TCM ideological therapy,TCM five-tone therapy,and TCM psychological sand table),and TCM nursing(dialectical care,dialectical diet,and psychological counseling).Anxiety and depression were the main outcomes evaluated in regard to mental health in patients with COVID-19.The limitations of methodological quality were predominantly from follow-up,blinding,and registration.Positive results were reported by 27 studies(90%,n=30).Conclusion:We summarized the existing literature about the impact of TCM on mental health in patients with COVID-19.The number of studies evaluating the impact of TCM on mental health is encouraging,but overall methodological quality was low.Several TCM interventions warrant further evaluation,particularly among populations outside of China,for the purpose of establishing supporting evidence.More importantly,research with stronger methodological quality needs to be developed.

Proteomics analysis of coronary atherosclerotic heart disease with different Traditional Chinese Medicine syndrome types before and after percutaneous coronary intervention

OBJECTIVE: To investigate the underlying protein molecular mechanisms of "Qi stagnation and blood stasis syndrome"(QS) and "Qi deficiency and blood stasis syndrome"(QD), as two subtypes of coronary artery disease(CAD) in Traditional Chinese Medicine(TCM),following percutaneous coronary intervention(PCI).METHODS: In this study, a total of 227 CAD patients with QS and 211 CAD patients with QD were enrolled;all participants underwent PCI. Label-free quantification proteomics were employed to analyze the changes in serum in two subtypes of CAD patients before and 6 months after PCI, aiming to elucidate the intervention mechanism of PCI in treating CAD characterized by two different TCM syndromes.RESULTS: Biochemical analysis revealed significant changes in tumor necrosis factor-α, high density lipoprotein cholesterol, blood stasis clinical symptoms observation, and Gensini levels in both patient groups post-PCI;Proteomic analysis identified 79 and 95 differentially expressed proteins in the QS and QD patient groups, respectively, compared to their control groups.complement C8 alpha chain, complement factor H,apolipoprotein H, apolipoprotein B, plasminogen,carbonic anhydrase 2, and complement factor Ⅰ were altered in both comparison groups. Furthermore,enrichment analysis demonstrated that cell adhesion and connectivity-related processes underwent changes in QS patients post-PCI, whereas lipid metabolism-related pathways, including the peroxisome proliferator-activated receptor signaling pathway and extracellular matrix receptor interaction, underwent changes in the QD group.The protein-protein interaction network analysis further enriched 52 node proteins, including apolipoprotein B,lipoprotein(a), complement C5, apolipoprotein A4,complement C8 alpha chain, complement C8 beta chain,complement C8 gamma chain, apolipoprotein H,apolipoprotein A-Ⅱ, albumin, complement C4-B,apolipoprotein C3, among others. The functional network of these proteins is posited to contribute to the pathophysiology of CAD characterized by TCM syndromes.CONCLUSION: The current quantitative proteomic study has preliminarily identified biomarkers of CAD in different TCM subtypes treated with PCI, potentially laying the groundwork for understanding the protein profiles associated with the treatment of various TCM subtypes of CAD.

Assessment of the Clinical Effect of Chinese Medicine Therapy Combined with Psychological Intervention for Treatment of Patients of Peri-menopausal Syndrome Complicated with Hyperlipidemia

Objective：To observe the effect of Chinese medicine therapy combined with psychological intervention（combined therapy） on the clinical symptoms and levels of blood lipids and sex hormones of patients of peri-menopausal syndrome complicated with hyperlipidemia.Methods：With the use of a randomizing digital table method,185 patients that fit the registration standard were randomly assigned to three groups.The 59 cases in Group A were treated with two Chinese patents,Kunbao Pill（坤宝丸） and Modified Xiaoyao Pill（加味逍遥丸）;the 63 in Group B received psychological intervention alone;and the 63 in Group C were treated with both（the combined therapy）,with the treatment course for all six months.The items of observation included： （1） scoring by SCL-90 on eight factors and seven symptoms;（2） scoring on Chinese medicine symptoms by Kupermann scale,including anxiety and bad temper,scorching sense ation with sweating,dizziness,tinnitus, soreness and weakness of the loin and knees,palpitation,insomnia,lassitude,weakness,and hyposexuality; （3） blood contents of total cholesterol（TC）,triglyceride（TG）,high-density lipoprotein cholesterol（HDL-C）, low-density lipoprotein cholesterol（LDL-C）,apoprotein Al（ApoAl） and B（ApoB）;（4） levels of sex hormones, including estradiol（E_2）,progesterone（P）,pituitary prolactin（PRL）,follicular stimulating hormone（FSH）,and luteinzing hormone（LH） in some randomly selected patients;（5） adverse reaction;and（6） one-year follow-up study on long-term effect.Results：A total of 21 patients（6,8,and 7 cases in Groups A,B,and C,respectively） dropped out;the drop-out rate was insignificant among groups.（1） The markedly effective rates in Group A, B,and C were 26.42%（14/53）,18.18%（10/55）,and 53.57%（30/56）,respectively,and the total effective rates in them were 64.15%（34/53）,50.91%（28/55）,and 87.50%（49/56）,respectively,suggesting the therapeutic efficacy in Group C was significantly better than that in Groups A and B（P〈0.01）.（2） SCL-90 scoring showed that the total scores decreased significantly after treatment in Group C（P〈0.01）,but remained unchanged in Groups A and B（P〉0.05）.（3） Scoring on Chinese medicine symptoms showed the same results as shown by SCL-90 scoring in terms of total scores and individual symptoms,except that menstrual disorder and amenorrhea were unchanged in all three groups（P〉0.05）.（4） Levels of HDL-C,ApoAl,and E_2 increased and those of TG,TC,LDL-C,ApoB,FSH,and LH decreased after treatment in Group C,reaching near normal levels;similar trends of blood lipids were shown in Group A,but the level of sex hormones was unchanged.In Group B all the above-mentioned indices were unchanged（P〉0.05）.（5） A one-year follow-up study showed the markedly effective rate and the total effective rate in Group C were higher than those in the other two groups respectively（P〈0.01）.（6） No adverse reaction was found.Conclusion：Chinese medicine therapy combined with psychological intervention could not only improve the nervous symptoms,but also regulate the blood levels of lipids and sex hormones in patients of peri-menopausal syndrome complicated with hyperlipidemia.

A comprehensive update:gastrointestinal microflora,gastric cancer and gastric premalignant condition,and intervention by traditional Chinese medicine

With the recent upsurge of studies in the field of microbiology,we have learned more about the complexity of the gastrointestinal microecosystem.More than 30 genera and 1000 species of gastrointestinal microflora have been found.The structure of the normal microflora is relatively stable,and is in an interdependent and restricted dynamic equilibrium with the body.In recent years,studies have shown that there is a potential relationship between gastrointestinal microflora imbalance and gastric cancer(GC)and precancerous lesions.So,restoring the balance of gastrointestinal microflora is of great significance.Moreover,intervention in gastric premalignant condition(GPC),also known as precancerous lesion of gastric cancer(PLGC),has been the focus of current clinical studies.The holistic view of traditional Chinese medicine(TCM)is consistent with the microecology concept,and oral TCM can play a two-way regulatory role directly with the microflora in the digestive tract,restoring the homeostasis of gastrointestinal microflora to prevent canceration.However,large gaps in knowledge remain to be addressed.This review aims to provide new ideas and a reference for clinical practice.

Early therapeutic interventions of traditional Chinese medicine in COVID-19 patients:A retrospective cohort study

Objective:To observe the early interventions of traditional Chinese Medicine(TCM)on the conversion time of nucleic acid in patients with coronavirus disease 2019(COVID-19),and find possible underlying mechanisms of action.Methods:A retrospective cohort study was conducted on 300 confirmed COVID-19 patients who were treated with TCM,at a designated hospital in China.The patients were categorized into three groups:TCM1,TCM2 and TCM3,who respectively received TCM interventions within 7,8–14,and greater than15 days of hospitalization.Different indicators such as the conversion time of pharyngeal swab nucleic acid,the conversion time of fecal nucleic acid,length of hospital stay,and inflammatory markers(leukocyte count,and lymphocyte count and percentage)were analyzed to observe the impact of early TCM interventions on these groups.Results:The median conversion times of pharyngeal swab nucleic acid in the three groups were 5.5,7 and16 d(P<0.001),with TCM1 and TCM2 being statistically different from TCM3(P<0.01).TCM1(P<0.05)and TCM3(P<0.01)were statistically different from TCM2.The median conversion times of fecal nucleic acid in the three groups were 7,9 and 17 d(P<0.001).Conversion times of fecal nucleic acid in TCM1 were statistically different from TCM3 and TCM2(P<0.01).The median lengths of hospital stay in the three groups were 13,16 and 21 d(P<0.001).TCM1 and TCM2 were statistically different from TCM3(P<0.01);TCM1 and TCM3 were statistically different from TCM2(P<0.01).Both leucocyte and lymphocyte counts increased gradually with an increase in the length of hospital stay in TCM1 group patients,with a statistically significant difference observed at each time point in the group(P<0.001).Statistically significant differences in lymphocyte count and percentage in TCM2(P<0.001),and in leucocyte count(P=0.043)and lymphocyte count(P=0.038)in TCM3 were observed.The comparison among the three groups showed a statistically significant difference in lymphocyte percentage on the third day of admission(P=0.044).Conclusion:In this study,it was observed that in COVID-19 patients treated with a combination of Chinese and Western medicines,TCM intervention earlier in the hospital stay correlated with faster conversion time of pharyngeal swab and fecal nucleic acid,as well as shorter length of hospital stay,thus helping promote faster recovery of the patient.The underlying mechanism of action may be related to improving inflammation in patients with COVID-19.

A traditional Chinese herbal medicine compound preparation versus interventional therapy after resection of small hepatocellular carcinoma:22-year follow-up

OBJECTIVE:To compare the long-term effectiveness of compound Ruanjianhugan(RJH)tablets and interventional therapy(IT) in patients after resection of small hepatocellular carcinoma(HCC).METHODS:A retrospective study was conducted in 399 patients after resection of small HCC who were admitted between January 1987 and December 2008 in the Department of Hepatobiliary Surgery and Center of Minimlly Invasive Surgery,First Affiliated Hospital of Guangxi Medical University.Four groups were based on different therapy modes:a TCM-only(TCMO) group,a TCM combined with interventional therapy(TCM-IT) group,an interventional therapy-only(ITO) group,and a simple operation(SO) group.Prognostic factors were correlated with overall survival(OS) and OS rates were calculated with the Kaplan-Meier method,and multivariate analyses for factors affecting survival were evaluated by the Cox proportional hazard model.RESULTS:The median OS was 151.20 months in the TCM-IT group,43.87 months in the ITO group,and 20.77 months in the SO group.All survival rates of the TCMO group were higher than those of the other three groups(>50%).The 5-,10-,and 15-year OS in the TCMO and ITO patients were 83.94%,45.50%,and 71.22% and 33.34%,55.58%,and 9.26%,respectively(risk ratio,0.209;95% confidence interval,0.126-0.347;P=0.000).Multivariate analysis revealed that the independent risk factors were therapy mode(P=0.000),sex(P=0.005),family history(P=0.011),TNM Classification of Malignant Tumor staging(P=0.000),medical care-seeking behavior(P=0.021),and maximum diameter(P=0.030).CONCLUSION:Long-term oral use of compound RJH tablets may improve OS for small HCC after resection compared with IT.

Multi-centric clinical study of the effect of intervention time on efficacy of gastroparesis external application prescription treatment of gastrointestinal tumor postsurgical gastroparesis

Objective:This intervention has been shown to be clinically efficacious and safe.The aim of this study was to determine the effect of different intervention times on the efficacy of gastroparesis external application prescription versus placebo for the treatment of gastrointestinal tumor postoperative,postsurgical gastroparesis.Methods:A multicenter,randomized,double-blind,placebo controlled phaseⅢclinical trial was designed to demonstrate superiority and conducted at four grade 3A hospitals in Beijing.Patients diagnosed with gastrointestinal tumor postsurgical gastroparesis and local cold syndrome in the abdomen were enrolled and received conventional treatment(nutritional support,gastrointestinal decompression,and prokinetic medication).Treatment and control groups respectively received gastroparesis external application prescription or placebo acupoint application over a treatment course of 14 days or until the primary efficacy endpoint(clinical efficiency)was achieved.Results:A total of 120 patients were enrolled in the treatment and control groups(n Z 60 per group),and 15 patients dropped out of the study because of skin allergies(n Z 7)or poor efficacy(nZ8).The efficacy among patients in Class B of Group A(treatment group)was marginally better than that of Group B(control group)(64.28%vs.55.56%)although the difference between the two groups was not significant.However,the efficacy among patients in Class C of Group A was significantly better than that of Group B(79.49%vs.43.33%).For Group A,the time for patients in the three classes to achieve the efficacy endpoint increased significantly with disease progression(3.00,6.78,and 8.29 days for Class A,B,and C,respectively).Conclusions:Gastroparesis external application prescription can effectively treat gastrointestinal tumor postsurgical gastroparesis and may be more efficacious in progressive disease compared placebo.Patients with gastrointestinal tumor postsurgical gastroparesis should therefore undergo intervention at an earlier stage.

Classification of interventions in Traditional Chinese Medicine

OBJECTIVE: To describe the key systems used for Traditional Chinese Medicine(TCM) classification.METHODS: The TCM classifications used in the International Classification of Diseases-9 Clinical Modification(ICD-9-CM) volume 3, the ICD-10 Procedure Coding System, the International Classification of Health Interventions, and the Medical Subject Headings(Me SH) and Chinese Traditional Medicine and Materia Medica Subject Headings(TCMe SH) thesauruses were compared regarding descriptive terms, structure, and features of TCM interventions.RESULTS: The National Library of Medicine's Me SH thesaurus is ubiquitous. The ICD-9-CM(volume 3),ICD-10 Procedure Coding System, and International Classification of Health Interventions cover insufficient concepts of TCM, and cannot be used directly as classification systems for TCM interventions. In contrast, the TCM contents of the TCMe SH thesaurus are complete, systematic, and detailed, and its hierarchical structure can be used for effective TCM classification.CONCLUSION: TCM classification is very limited and flawed. The Me SH thesaurus helps decrease the detrimental effect of the language barrier. Similarly, the TCMe SH thesaurus can help those without full command of the Mandarin language to access Chinese literature, but the value of searches using TCMe SH could be improved by collaborative working with Information Specialists who are fluent in Mandarin and understand TCM.

Spaceflight-associated neuro-ocular syndrome:a review of potential pathogenesis and intervention

With the continuing progress in space exploration,a new and perplexing condition related to spaceflight ocular syndrome has emerged in the past four decades.National Aeronautics and Space Administration(NASA) has named this condition "spaceflight-associated neuro-ocular syndrome"(SANS).This article gives an overview of the current research about SANS and traditional Chinese medicine(TCM) by analyzing the existing publications on Pub Med and CNKI and reports from NASA about SANS,summarizing the potential pathogenesis of SANS and physical interventions for treating SANS,and discussing the feasibility of treating SANS with TCM.Due to the unique characteristics of the space environment,it is infeasible to conduct large-scale human studies of SANS.SANS may be the result of the interaction of multiple factors,including inflammation and fluid displacement in the optic nerve sheath and cerebrospinal fluid.We should pay attention to SANS.Visual function is not only related to the health of astronauts but also closely related to space operations.TCM has antioxidative stress and antiapoptotic effects and is widely used for optic nerve diseases.TCM has great potential to prevent SANS.

Study on the Psychological Mechanism and Application of Horticultural Therapy

Horticultural therapy has a long history,and its application in China has been delayed for more than 20 years than that in the United States and the United Kingdom.The psychological mechanism of horticultural therapy is mainly to improve emotional cognition and emotional state,and promote physical and mental health.Based on the character of traditional Chinese medicine,combined with the modern probiotics and the environmental protection measures of sewage treatment,the research of preventing and treating insomnia and depression was carried out by using the living Chinese herbal medicine ecosystem,and good results were obtained.Based on the concepts of traditional Chinese medicine,big health and environment protection,the mechanism of horticultural therapy should be further studied.Horticultural therapy should be integrated extensively in the construction of landscaping,to construct horticultural therapy system with Chinese characteristics.

经皮穴位电刺激联合中医情志干预对腹腔镜直肠癌根治术患者免疫功能和心理应激的影响

【目的】评价经皮穴位电刺激(TEAS)联合中医情志干预对腹腔镜直肠癌根治术患者免疫功能和心理应激的影响。【方法】将100例住院拟行腹腔镜直肠癌根治术治疗的患者随机分为A、B、C、D 4组,每组各25例。A组给予麻醉前TEAS 30 min,B组给予持续TEAS至手术结束,C组给予麻醉前TEAS 30 min+中医情志干预,D组给予持续TEAS至手术结束+中医情志干预,其中,TEAS取穴足三里(双侧)、三阴交(双侧)、百会、内关(双侧)。观察各组围术期指标以及术前与术后3 d免疫功能指标、Th1/Th2细胞分子机制、心理应激反应指标的变化情况,并比较各组的不良反应发生情况。【结果】(1)围术期指标方面,4组患者的手术时间、出血量、输液量比较,差异均无统计学意义(P>0.05);D组的舒芬太尼用量、瑞芬太尼用量、术后苏醒时间、术后24 h痛觉模拟量表(VAS)评分均低于A组、B组、C组(P<0.05),而B组、C组的上述指标均低于A组(P<0.05)。(2)免疫功能指标方面,D组术后3 d的T淋巴细胞亚群CD3+、CD4+及自然杀伤(NK)细胞水平均高于A组、B组、C组(P<0.05),而B组、C组的上述指标均高于A组(P<0.05)。(3)Th1/Th2细胞分子机制方面,D组术后3 d的血清白细胞介素2(IL-2)、γ干扰素(IFN-γ)水平均高于A组、B组、C组(P<0.05),血清白细胞介素10(IL-10)水平均低于A组、B组、C组(P<0.05),而B组、C组的血清IL-2、IFN-γ水平均高于A组(P<0.05),血清IL-10水平均低于A组(P<0.05)。(4)心理应激反应指标方面,D组术后3 d的焦虑自评量表(SAS)和抑郁自评量表(SDS)评分均低于A组、B组、C组(P<0.05),而B组、C组的上述评分均低于A组(P<0.05)。(5)不良反应方面,A组出现1例恶心呕吐,B组出现2例恶心呕吐、1例头晕,C组无不良反应,D组出现1例恶心呕吐,不良反应发生率分别为4.0%(1/25)、12.0%(3/25)、0.0%(0/25)、4.0%(1/25),组间比较,差异无统计学意义(χ2=0.400,P=0.527)。【结论】针对腹腔镜直肠癌根治术患者,TEAS联合中医情志干预可有效调节患者围术期免疫功能,减轻应激反应,缓解患者紧张焦虑状态,同时可产生一定的镇痛作用,减少阿片类药物用量,提高患者围术期舒适度及手术耐受水平。

综合评估指导的中医护理干预在老年COPD患者中的应用效果

目的分析老年慢性阻塞性肺疾病(COPD)患者实施综合评估为指导的中医护理干预,对其衰弱状态、生活质量、肺功能及营养状态的影响,旨在改善老年COPD患者的衰弱状态,提高其生活质量和功能独立性,对于优化老年COPD患者的管理和护理提供依据。方法研究对象为启东市中医院呼吸内科在2021年4月—2023年3月收治且符合研究要求的COPD患者180例,基于组间基线资料具有可比性条件下将纳入患者分为对照组和观察组各90例。对照组行常规护理干预,观察组患者给予老年综合评估指导下的中医护理干预。比较观察两组患者衰弱状态、肺功能水平[第一秒用力呼气容积占用力肺活量百分比(FEV_(1)/FVC)、第一秒用力呼气容积占预计值百分比(FEV_(1)%)]、营养状况[血清总蛋白(TP)、白蛋白(ALB)水平和NRS-2002评分]以及生活质量[慢性阻塞性肺疾病评分(CAT)]变化情况。结果干预前两组患者衰弱状态分级、TP、ALB水平、NRS-2002评分、FEV_(1)/FVC、FEV_(1)%水平、CAT评分比较差异无统计学意义(P>0.05)。干预后,观察组患者衰弱状态轻于对照组,观察组TP、ALB水平高于对照组,NRS-2002评分低于对照组,观察组FEV_(1)/FVC、FEV_(1)%水平高于对照组,观察组CAT评分低于对照组,两组以上指标比较差异均有统计学意义(P<0.05)。结论老年综合评估指导下的中医护理干预策略可进一步提高患者营养水平和肺功能,最终改善患者衰弱状态,减轻COPD对生活质量的影响。

中医药干预白血病干细胞免疫逃逸研究进展

白血病是目前临床上高发的急危重症,病死率极高,其中白血病干细胞(leukemia stem cells,LSC)发生免疫逃逸是白血病诱导缓解后复发及进展的主要因素。中医药(Traditional Chinese Medicine,TCM)临床诊疗具有鲜明的辨证论治优势,基于“以平为期”的诊治目的,中医药辨治白血病强调恢复人体机能的“阴阳和谐”,有助于提高机体自身免疫力,符合干预肿瘤细胞免疫逃逸的机制。本文从文献研究及中医理论探讨中医药干预LSC免疫逃逸的机制及其研究进展。

中药雾化熏洗配合特定电磁波谱照射在肛瘘患者术后的应用效果

目的探讨中药雾化熏洗配合特定电磁波谱(TDP)照射在肛瘘患者术后干预的临床效果。方法选取2022年10月至2023年10月九江市第一人民医院120例肛瘘患者作为研究对象,根据治疗方法不同分为观察组(59例)与对照组(61例)。两组均采用肛瘘切除术治疗,对照组术后采用高锰酸钾溶液外洗联合TDP照射,观察组术后采用中药雾化熏洗配合TDP照射。比较两组的临床总有效率、术后创面恢复时间、未治疗、治疗下创面分泌物、红肿问题、肉芽形态、炎症因子、疼痛、并发症。结果观察组总有效率高于对照组,差异有统计学意义(P<0.05);观察组术后疼痛消失时间、水肿消失时间、渗血消失时间、便血消失时间、创面愈合时间短于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者创面分泌物评分、肉芽形态评分、红肿程度评分低于对照组,差异有统计学意义(P<0.05);观察组视觉模拟评分法(VAS)评分、并发症发生率低于对照组,差异有统计学意义(P<0.05);观察组超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)水平低于对照组,差异有统计学意义(P<0.05)。结论肛瘘患者在术后干预中采用中药雾化熏洗配合TDP照射的效果较显著,不仅可以有效缩短其术后创面恢复时间,改善创面分泌物、肉芽形态及红肿情况,还可以减轻其疼痛程度和炎症反应,减少并发症的发生。

基于中医情志护理的健康宣教结合五音疗法对冠心病经皮冠状动脉介入术术后患者焦虑抑郁及睡眠质量的影响

目的观察基于中医情志护理的健康宣教结合五音疗法对冠心病经皮冠状动脉介入术(PCI)术后患者焦虑抑郁及睡眠质量的影响。方法选择2022年1月至2023年8月赣南医学院第一附属医院收治的60例行PCI的冠心病患者为研究对象,按照随机数字表法将其分为对照组(30例)、观察组(30例),对照组采用常规护理,观察组采用基于中医情志护理的健康宣教结合五音疗法护理。比较两组患者的睡眠质量、焦虑和抑郁情绪、健康行为、中医证候积分情况。结果观察组护理后的Spiegel睡眠量表评分低于对照组,差异有统计学意义(P<0.05)。观察组护理后的焦虑自评量表(SAS)、抑郁自评量表(SDS)评分均低于对照组,差异有统计学意义(P<0.05)。观察组护理后的健康行为评分高于对照组,差异有统计学意义(P<0.05)。观察组护理后的心胸疼痛、胸闷、心悸、气短、心中烦躁、夜寐不安、精神不振评分均低于对照组,差异有统计学意义(P<0.05)。结论冠心病PCI术后给予患者基于中医情志护理的健康宣教结合五音疗法,可明显改善患者睡眠质量、心理状态,缓解患者心胸疼痛、胸闷、心悸等症状,改善患者健康行为,可广泛应用。

益气养阴化瘀汤对冠心病经皮冠状动脉介入治疗术后患者心功能和血管内皮功能的影响

目的观察益气养阴化瘀汤对冠心病经皮冠状动脉介入治疗(PCI)术后患者心功能及血管内皮功能的影响。方法将62例冠心病PCI术后患者按照随机数字表法分为2组。对照组31例予常规抗血小板聚集、稳定斑块等药物治疗,治疗组31例在对照组治疗基础上加用益气养阴化瘀汤治疗,均治疗4周。比较2组治疗前后中医症状评分、血管内皮功能[血清一氧化氮(NO)、血管内皮生长因子(VEGF)、内皮素-1(ET-1)]、心功能[心脏每搏输出量(SV)、左心室射血分数(LVEF)、左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)及左心室收缩末期容积(LVESV)]、血液流变学指标[全血黏度(CP)、血浆黏度(PV)、红细胞比容(Hct)及红细胞聚集指数(AI)]变化,并比较2组心绞痛疗效和不良事件发生率。结果治疗后,2组中医症状胸闷疼痛、心悸盗汗、五心烦热及失眠多梦评分及总分均较本组治疗前下降(P<0.05),且治疗组均低于对照组(P<0.05)。治疗后,2组NO及VEGF水平均较本组治疗前上升(P<0.05),且治疗组高于对照组(P<0.05);治疗后,2组ET-1水平均较本组治疗前下降(P<0.05),且治疗组低于对照组(P<0.05)。治疗后,2组LVEF及SV均较本组治疗前上升(P<0.05),且治疗组高于对照组(P<0.05);治疗后,2组LVEDD、LVESD及LVESV均较本组治疗前下降(P<0.05),且治疗组低于对照组(P<0.05)。治疗后,2组CP、PV、Hct及AI水平均较本组治疗前下降(P<0.05),且治疗组低于对照组(P<0.05)。治疗组心绞痛疗效总有效率为87.10%(27/31),不良事件发生率6.45%(2/31),对照组分别为64.52%(20/31)、16.13%(5/31),治疗组心绞痛疗效总有效率高于对照组(P<0.05),2组不良事件发生率比较差异无统计学意义(P>0.05)。结论益气养阴化瘀汤可有效改善冠心病PCI术后患者心功能和血管内皮功能,且未增加不良事件发生。